igfbp2a (igfbp2)



Basic Information


Item Value
gene id igfbp2a
gene name igfbp2
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information


Item Value
chromosome id NC_053135.1
NCBI id CM020932.1
chromosome length 21835524
location 11506509 ~ 11522886 (+)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence


>XM_039792848.1
AGCAAACCTGGGAATTTGTAGGACCCAGCAGACCTCCCAGCCCCCGGCTTCACCTGTTCGCATACACAtttcttccccctttttttcacTTGGGATTGCCTTCCATCGCCCCATGATAATGACCAAAAACCTCATGCCTTTAACAATGCTGTCGTACGCGGGCTGCAGCTTGCTGATCCTCGGTGCGTCTCTCGCCGGTGCCTCCCTGGCCGAGATGGTGTTCCGCTGTCCCGGCTGCACCGCGGAGCGCCAGGCGCTATGCCCAAGGCTCACCGAGACTTGTGCAGAGATAGTGCGCGAACCGGGCTGCGgatgttgccccgtgtgcgcccGGCAAGAGGGCGAGATGTGCGGCGTGTACACCCCGAGGTGCTCCACCGGTCTGCGATGCTACCCGACGCCAGACTCGGAGCTTCCTCTGGAGCAACTGGTGCAGGGCCAGGGGCAATGCCGGCGCAAAGTGGACACCGAGACGACCACGTACAGCCAGGAGCACCGGGAGCAAACAAGCGGCGAGGCTGTGGAGGCGCTGCCTGAGCAGGGTGTGAGTGAGATCCCGGCCATCCGAAAGCCCAGCAAAGAGACCACCTGGCTGGGACCCAAAGAGAGCGCTGTGCGCCAGCACAGACAGGAGATGAAGACCAAGATGAAGACCAACaaggtggaggaggtgaaacCTGCACGGCCCAAACAGACTCAGTGTCAGCAGGAGCTCGACCAGATCCTGGAGAGGATATCTAAGATGCCCTTCAGAGATAACCGAGGTCCCCTGGAAGACCTGTATGCCCTGCACATCCCCAACTGCGACAAGAGGGGGCAGTATAATCTCAAACAGTGCAAGATGTCTCTCCACGGTCAGAGGGGCGAGTGTTGGTGCGTCAACCCTCACACTGGCCGACCTATCCCATCAGCCCCTACTGTGAGGGGCGACCCCAACTGCAGCCAGTACCTCACCGAGCTGGAGCTAGAGCTTCCTGACATGGCCCAGATATAATGCGTCAtgaaacaaaaactgtaaaagtacTTGGGAACAAAGAACATCTGAGTAAGCTATATATTATCTTtccgtgtgtatgtgtctctagTTCATTTGATGAAATCTTAACCACCAGAAAGGATTAAATGATAGAATCCAGCTTGCTGAGGGTGTAACTGCAGATAATTTGTAGGTGAAGTAAAAAAATCAGGCTCCCTTTTCCTCGTAGCTATTCAGTAGACGTCAACTGGAGTGCCGGTGACTTTGCTTTACTAATTTTGACTTAGCTCAGATTTGCTCCGTTATCAGTGTTTTGTACTGTATTGTATGTGTTGAAAAATGAAAAGCCTtcaacatatttgttttttttaggtgcGTTTTCCTGTCCTAGCTTGCAGACTACTGTCACGCCTAATTAACAGATAATGCTAATAAAATGGTAATACATTCA

Function


symbol description
igfbp2 Enables insulin-like growth factor I binding activity. Involved in positive regulation of activated T cell proliferation. Located in extracellular space. Implicated in obesity. Biomarker of Alzheimer's disease; Kuhnt-Junius degeneration; and obesity.

NR:

description
PREDICTED: insulin-like growth factor-binding protein 2

GO:

id name namespace
GO:0043567 regulation of insulin-like growth factor receptor signaling pathway biological_process
GO:0007507 heart development biological_process
GO:0008156 negative regulation of DNA replication biological_process
GO:0001525 angiogenesis biological_process
GO:0001558 regulation of cell growth biological_process
GO:0008285 negative regulation of cell population proliferation biological_process
GO:0048640 negative regulation of developmental growth biological_process
GO:0040015 negative regulation of multicellular organism growth biological_process
GO:0005576 extracellular region cellular_component
GO:0031994 insulin-like growth factor I binding molecular_function
GO:0031995 insulin-like growth factor II binding molecular_function

KEGG:

id description
K23575 IGFBP2; insulin-like growth factor-binding protein 2

RNA


RNA id representative length rna type GC content exon number start site end site
XM_039792848.1 True 1427 mRNA 0.53 4 11506509 11522886

Neighbor


gene id symbol gene type direction distance location
inha NA coding upstream 47789 11456007 ~ 11458720 (+)
LOC120554163 NA coding upstream 56673 11441810 ~ 11449836 (+)
LOC120554145 NA coding upstream 175963 11324005 ~ 11330546 (+)
slc19a1 slc19a1 coding upstream 202176 11293687 ~ 11304333 (+)
LOC120554141 NA coding upstream 215395 11275005 ~ 11291114 (+)
mettl21a mettl21a,LOC102786790 coding downstream 193519 11716405 ~ 11717508 (+)
LOC120554157 LOC104957756,LOC104928318,LOC101466657,LOC100697713 coding downstream 264060 11786946 ~ 11821870 (+)
si:ch211-93g23.2 NA coding downstream 310371 11833257 ~ 11837137 (+)
lancl1 lancl1 coding downstream 666612 12189498 ~ 12201382 (+)
mylz3 LOC101075868,LOC104929359 coding downstream 682214 12205100 ~ 12208594 (+)
G234117 NA non-coding upstream 45939 11458967 ~ 11460570 (+)
LOC120554172 NA non-coding upstream 70307 11432670 ~ 11436202 (+)
G234088 NA non-coding upstream 163093 11343166 ~ 11343416 (+)
G234087 NA non-coding upstream 164219 11341980 ~ 11342290 (+)
G234081 NA non-coding upstream 168884 11337366 ~ 11337625 (+)
G234135 NA non-coding downstream 48122 11571008 ~ 11572562 (+)
G234137 NA non-coding downstream 51516 11574402 ~ 11577940 (+)
G234145 NA non-coding downstream 198669 11721555 ~ 11723072 (+)
G234187 NA non-coding downstream 265121 11788007 ~ 11800449 (+)
LOC120554173 NA non-coding downstream 319490 11842376 ~ 11844387 (+)
G234095 NA other upstream 111163 11393664 ~ 11395346 (+)
G234085 mest other upstream 126406 11362541 ~ 11380103 (+)
gemin8 gemin8 other upstream 457102 11046296 ~ 11049407 (+)
pln NA other upstream 916427 10579826 ~ 10590082 (+)
trnas-cga_10 NA other upstream 1117454 10388974 ~ 10389055 (+)
LOC120554149 erbb4,LOC102292440,LOC101467929,LOC100701577 other downstream 329503 11852389 ~ 12152440 (+)
LOC120554357 NA other downstream 776746 12299632 ~ 12357177 (+)
LOC120554058 obsl1,LOC102777652 other downstream 835141 12358027 ~ 12369221 (+)
LOC120554049 ect2l other downstream 1263755 12786641 ~ 12797654 (+)
G234425 tsc22d1,LOC106531085,LOC102196627 other downstream 1480077 13002963 ~ 13025520 (+)

Expression



Co-expression Network