XLOC_005070 (mapk8b)


Basic Information

Item Value
gene id XLOC_005070
gene name mapk8b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007123.7
NCBI id CM002896.2
chromosome length 49182954
location 2505519 ~ 2522487 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00009865
GTGCTTGTGTCTTGTGTGGAAAGACAAATACAACAACCCGCTGAGAAGACCCCAGTGTTTTTATGATTCTACACTTGAATTGTCTGTTCATCTTTTAGGAGGATTTTTGAAGGTGAAGCTCTTCTTGAATGCCCAGGATACAGTCAGTACGGTTTTCATCATGAACAGGAATAAGCGCGAGAAAGAATATTACAGCATAGATGTAGGAGATTCAACGTTCACCGTTTTGAAGCGCTATCAGAATTTAAGACCAATCGGGTCCGGAGCACAAGGCATCGTCTGCTCAGCGTATGACCACGTCCTCGATCGAAATGTGGCAATTAAGAAACTCAGCCGACCCTTTCAAAACCAAACTCATGCCAAACGGGCCTACAGAGAACTGGTCCTGATGAAATGCGTCAACCACAAAAATATAATTGGCTTACTAAACGTGTTCACACCACAGAAGACACTTGAAGAGTTCCAGGATGTTTATCTGGTGATGGAGCTGATGGATGCAAACCTGTGTCAGGTGATTCAGATGGAGCTGGACCACGAGAGGCTGTCCTACCTGCTCTATCAGATGCTCTGCGGCATTAAACACCTGCACGCTGCTGGCATCATACACAGGGATCTGAAACCCAGTAATATAGTAGTGAAATCGGACTGCACGCTGAAGATCCTGGATTTCGGTCTGGCCCGAACGGCTGCAACCGGCCTCCTCATGACTCCTTATGTCGTGACACGCTATTATCGGGCCCCAGAGGTCATCCTGGGCATGGGTTATCAAGCTAACGTTGATGTCTGGTCTATTGGCTGCATCATGGCTGAAATGGTCAGAGGTAGTGTGTTGTTTCCTGGCACAGACCATATTGACCAGTGGAATAAAGTGATCGAGCAGCTGGGCACGCCGTCACAGGAGTTCATGATGAAGCTGAATCAGTCTGTGAGGACGTATGTGGAGAACCGGCCTCGGTATGCGGGATACAGCTTTGAGAAGCTCTTCCCAGACGTGCTCTTCCCCGCAGACTCGGACCACAACAAACTCAAGGCGAGTCAGGCACGAGACTTGTTATCCAAAATGCTGGTAATAGATGCATCCAAGCGGATCTCTGTAGACGAGGCGCTTCAGCACCCCTACATCAACGTTTGGTACGACCCATCAGAAGTGGAGGCGCCGCCACCAGCGATCACGGATAAACAGCTCGATGAGAGAGAACACTCAGTGGAAGAGTGGAAagAGCTCATATACAAGGAAGTGCTGGAATGGGAGGAGCGAACAAAAAATGGAGTGATCAGAGGACAGCCGGCCTCGCTAGCACAGGTGCAGCAGTGAGCAGTGACTCCCATGAGCCCTCGACGTCGTCCTCCTCCATAAACGATGTGTCGTCCATGTCCACCGAGGTCACGCTGACCTCAGACACCGACAGCAGTCAGGAGACGTCCAACGGAGCGCTGCACTGCTGCAGATGACCATCCTTCTTCAACCTCCGTCACCCTCTGAAATCCTTCATCACCTTCCATTGTCTTCTGTCATGATTCTTCATCCTCCAAAATGCTTCATCACCTTCCAAAATCATCTATTGTTCTCTGTCATGGTTCTTCATCCTCCAAAATCCTCCCATTGGCCTTTTAAAATCCTCCATCCTCCCCTGTCACCTTCCAAAATCCTCTAGCCCCCTCAAATATGCTCTGTTACCCTCTAAAATCCTCCATCCTTCTTTGTTTACCATCCAAAATCCTCAATCGCCCTCCAAATTCCTCCATTCTCCTCAGTTACCTTCCAAAATCCTCCATTGTCTTCATTCACCCTCCAAAATCCTCCACTACCCCGTAAATCCTCCATTACCCTCCAAAATCCCTCATTGTGTTTGTCAGGATTCTTCATCCTCTGTCGCCCTCCAAAATCCTTCATTTTCCTCCAAAATCCTCTGTCACCGGCAAAATCCTCCTACATTATCCTTCAAAATCCTTAATTGCCCTCCATTTTCCTCCAGAGTCCTCTGTCACCTCCAAAATCTCTTCATTCACCCTTCAAAATACTCAGTTGCCCTCTAAAATCCTCTATTTTCCTCTAGAA
>TCONS_00009866
ATGAACAGGAATAAGCGCGAGAAAGAATATTACAGCATAGATGTAGGAGATTCAACGTTCACCGTTTTGAAGCGCTATCAGAATTTAAGACCAATCGGGTCCGGAGCACAAGGCATCGTCTGCTCAGCGTATGACCACGTCCTCGATCGAAATGTGGCAATTAAGAAACTCAGCCGACCCTTTCAAAACCAAACTCATGCCAAACGGGCCTACAGAGAACTGGTCCTGATGAAATGCGTCAACCACAAAAATATAATTGGCTTACTAAACGTGTTCACACCACAGAAGACACTTGAAGAGTTCCAGGATGTTTATCTGGTGATGGAGCTGATGGATGCAAACCTGTGTCAGGTGATTCAGATGGAGCTGGACCACGAGAGGCTGTCCTACCTGCTCTATCAGATGCTCTGCGGCATTAAACACCTGCACGCTGCTGGCATCATACACAGGGATCTGAAACCCAGTAATATAGTAGTGAAATCGGACTGCACGCTGAAGATCCTGGATTTCGGTCTGGCCCGAACGGCTGCAACCGGCCTCCTCATGACTCCTTATGTCGTGACACGCTATTATCGGGCCCCAGAGGTCATCCTGGGCATGGGTTATCAAGCTAACGTTGATGTCTGGTCTATTGGCTGCATCATGGCTGAAATGGTCAGAGGTAGTGTGTTGTTTCCTGGCACAGACCATATTGACCAGTGGAATAAAGTGATCGAGCAGCTGGGCACGCCGTCACAGGAGTTCATGATGAAGCTGAATCAGTCTGTGAGGACGTATGTGGAGAACCGGCCTCGGTATGCGGGATACAGCTTTGAGAAGCTCTTCCCAGACGTGCTCTTCCCCGCAGACTCGGACCACAACAAACTCAAGGCGAGTCAGGCACGAGACTTGTTATCCAAAATGCTGGTAATAGATGCATCCAAGCGGATCTCTGTAGACGAGGCGCTTCAGCACCCCTACATCAACGTTTGGTACGACCCATCAGAAGTGGAGGCGCCGCCACCAGCGATCACGGATAAACAGCTCGATGAGAGAGAACACTCAGTGGAAGAGTGGAAagAGCTCATATACAAGGAAGTGCTGGAATGGGAGGAGCGAACAAAAAATGGAGTGATCAGAGGACAGCCGGCCTCGCTAGGTGCAGCAGTGAGCAGTGACTCCCATGAGCCCTCGACGTCGTCCTCCTCCATAAACGATGTGTCGTCCATGTCCACCGAGGTCACGCTGACCTCAGACACCGACAGCAGTCAGGAGACGTCCAACGGAGCGCTGCACTGCTGCAGATGA
>TCONS_00009867
GTGCTTGTGTCTTGTGTGGAAAGACAAATACAACAACCCGCTGAGAAGACCCCAGTGTTTTTATGATTCTACACTTGAATTGTCTGTTCATCTTTTAGGAGGATTTTTGAAGGTGAAGCTCTTCTTGAATGCCCAGGATACAGTCAGTACGGTTTTCATCATGAACAGGAATAAGCGCGAGAAAGAATATTACAGCATAGATGTAGGAGATTCAACGTTCACCGTTTTGAAGCGCTATCAGAATTTAAGACCAATCGGGTCCGGAGCACAAGGCATCGTCTGCTCAGCGTATGACCACGTCCTCGATCGAAATGTGGCAATTAAGAAACTCAGCCGACCCTTTCAAAACCAAACTCATGCCAAACGGGCCTACAGAGAACTGGTCCTGATGAAATGCGTCAACCACAAAAATATAATTGGCTTACTAAACGTGTTCACACCACAGAAGACACTTGAAGAGTTCCAGGATGTTTATCTGGTGATGGAGCTGATGGATGCAAACCTGTGTCAGGTGATTCAGATGGAGCTGGACCACGAGAGGCTGTCCTACCTGCTCTATCAGATGCTCTGCGGCATTAAACACCTGCACGCTGCTGGCATCATACACAGGGATCTGAAACCCAGTAATATAGTAGTGAAATCGGACTGCACGCTGAAGATCCTGGATTTCGGTCTGGCCCGAACGGCTGCAACCGGCCTCCTCATGACTCCTTATGTCGTGACACGCTATTATCGGGCCCCAGAGGTCATCCTGGGCATGGGTTATCAAGCTAACGTTGATGTCTGGTCTATTGGCTGCATCATGGCTGAAATGGTCAGAGGTAGTGTGTTGTTTCCTGGCACAGACCGTATCCTTACCTGGTTGTCTTTACTGTCCCATTTTAAgtgttgtctgtttgtttgtttgtttgtttgttttattttaccttAATATGTGTTGCCATTGATGCCTGAGACCAAATGAAACAAAggtagttttgtttttaatatgatgaaaaaaaaaaaaaaaagtccttgttTTACTTTGGA
>TCONS_00009868
CAGGATACAGTCAGTACGGTTTTCATCATGAACAGGAATAAGCGCGAGAAAGAATATTACAGCATAGATGTAGGAGATTCAACGTTCACCGTTTTGAAGCGCTATCAGAATTTAAGACCAATCGGGTCCGGAGCACAAGGCATCGTCTGCTCAGCGTATGACCACGTCCTCGATCGAAATGTGGCAATTAAGAAACTCAGCCGACCCTTTCAAAACCAAACTCATGCCAAACGGGCCTACAGAGAACTGGTCCTGATGAAATGCGTCAACCACAAAAATATAATTGGCTTACTAAACGTGTTCACACCACAGAAGACACTTGAAGAGTTCCAGGATGTTTATCTGGTGATGGAGCTGATGGATGCAAACCTGTGTCAGGTGATTCAGATGGAGCTGGACCACGAGAGGCTGTCCTACCTGCTCTATCAGATGCTCTGCGGCATTAAACACCTGCACGCTGCTGGCATCATACACAGGGATCTGAAACCCAGTAATATAGTAGTGAAATCGGACTGCACGCTGAAGATCCTGGATTTCGGTCTGGCCCGAACGGCTGCAACCGGCCTCCTCATGACTCCTTATGTCGTGACACGCTATTATCGGGCCCCAGAGGTCATCCTGGGCATGGGTTATCAAGCTAACGTTGATGTCTGGTCTATTGGCTGCATCATGGCTGAAATGGTCAGAGGTAGTGTGTTGTTTCCTGGCACAGACCGTATCCTTACCTGGTTGTCTTTACTGTCCCATTTTAAgtgttgtctgtttgtttgtttgtttgtttgttttattttaccttAATATGTGTTGCCATTGATGCCTGAGACCAAATGAAACAAAggtagttttgt

Function

symbol description
mapk8b Predicted to enable JUN kinase activity. Involved in JNK cascade. Acts upstream of or within determination of dorsal identity. Predicted to be located in synapse. Predicted to be active in cytoplasm and nucleus. Is expressed in brain; gut; and pectoral fin. Human ortholog(s) of this gene implicated in abdominal aortic aneurysm; colorectal adenoma; rectal benign neoplasm; and type 2 diabetes mellitus. Orthologous to human MAPK8 (mitogen-activated protein kinase 8).

GO:

id name namespace
GO:0048511 rhythmic process biological_process
GO:0035556 intracellular signal transduction biological_process
GO:0007254 JNK cascade biological_process
GO:0048263 determination of dorsal identity biological_process
GO:0006468 protein phosphorylation biological_process
GO:0010468 regulation of gene expression biological_process
GO:0016310 phosphorylation biological_process
GO:0045202 synapse cellular_component
GO:0005634 nucleus cellular_component
GO:0030054 cell junction cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005737 cytoplasm cellular_component
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function
GO:0004705 JUN kinase activity molecular_function
GO:0004707 MAP kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-010202-1 Predicted to enable JUN kinase activity. Involved in JNK cascade. Acts upstream of or within determination of dorsal identity. Predicted to be located in synapse. Predicted to be active in cytoplasm and nucleus. Is expressed in brain; gut; and pectoral fin. Human ortholog(s) of this gene implicated in abdominal aortic aneurysm; colorectal adenoma; rectal benign neoplasm; and type 2 diabetes mellitus. Orthologous to human MAPK8 (mitogen-activated protein kinase 8).

Ensembl:

ensembl_id ENSDARG00000009870

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00009865 False 2059 mRNA 0.48 12 2505519 2522487
TCONS_00009866 False 1287 mRNA 0.51 11 2506126 2518178
TCONS_00009867 False 1029 mRNA 0.44 7 2511879 2522487
TCONS_00009868 True 848 mRNA 0.46 6 2511927 2518205

Neighbor

gene id symbol gene type direction distance location
XLOC_005069 NA coding downstream 25588 2067963 ~ 2479931 (-)
XLOC_005068 NA coding downstream 503695 2000636 ~ 2001824 (-)
XLOC_005067 NA coding downstream 504029 2000019 ~ 2001490 (-)
XLOC_005066 sox9a coding downstream 554235 1947593 ~ 1951284 (-)
XLOC_005065 CABZ01081830.2 coding downstream 811466 1693014 ~ 1694053 (-)
XLOC_005071 CU929359.1 coding upstream 56750 2579237 ~ 2617510 (-)
XLOC_005072 NA coding upstream 103182 2625669 ~ 2669500 (-)
XLOC_005073 NA coding upstream 180868 2703355 ~ 2744641 (-)
XLOC_005074 ubtd1b coding upstream 257703 2780190 ~ 2800859 (-)
XLOC_005075 zdhhc16b coding upstream 327097 2849584 ~ 2869584 (-)
XLOC_005063 CU694266.1 non-coding downstream 1014931 1490472 ~ 1490588 (-)
XLOC_005062 NA non-coding downstream 1052180 1452900 ~ 1453339 (-)
XLOC_005083 NA non-coding upstream 759269 3281756 ~ 3284909 (-)
XLOC_005086 NA non-coding upstream 996681 3519168 ~ 3544016 (-)

Expression


Co-expression Network