ctsba (ctsb)



Basic Information


Item Value
gene id ctsba
gene name ctsb
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information


Item Value
chromosome id NC_053114.1
NCBI id CM020911.1
chromosome length 46923577
location 30867774 ~ 30876711 (-)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence


>XM_039794025.1
GTGGTTCCTAAGCGATATAAAGAGAAGAGGCGGACCATTTCATTTCACATACTTAATAATCACAGAGTTTCTGTTTATAGTGACAGACAAGTACATGAAAAAGGGGGACCTGAAGATCTGAAGTTCACACTACAGCTGACATACAAGCTACAggcAAAATGTGGCGTGCCGCCTTTCTCTTATTGGCTGCCAGCTTGTCAGTGAGCCTGGCCAGACCCCGCCTCCAACCACTGTCCAGTGAGATGGTCAACTACATCAATAAGATCAACACTACCTGGaagGCTGGTCACAACTTCCATAATGTCGACTACAGTTATGTCAGGAGACTCTGCGGTACGATGCTGAAGGGGCCTAAACTGCCAGTCATGGTTCAGTATGCTGGAGACCTGAAGCTGCCTAAGAACTTTGACTCCAGAGAGCAGTGGCCCAACTGTCCCACTCTGAAGGAGATCCGAGACCAGGGCTCCTGTGGATCCTGCTGGGCTTTTGGCGCTGCAGAGGCCATCTCTGACCGTGTGTGTATCCACAGCAATGCCAAGGTTAGCGTGGAGATCTCCTCAGAGGATCTGCTGACCTGCTGCGACAGCTGTGGCATGGGATGTAATGGTGGCTACCCTTCATCTGCCTGGGACTTCTGGACCAAAGCAGGGCTGGTCTCTGGAGGTCTCTATGACTCCCACATTGGTTGTCGGCCCTACACCATCCCCCCCTGTGAACACCACGTGAATGGCAGCAGACCCGCCTGCTCTGGGGAGGGTGGAGACACACCCAAGTGCACCCAGAAGTGTGAAGCTGGATACACACCTGGCTACAAAGCGGACAAGCACTTTGGTAAAACTTCTTACAGCGTGCTGTCAGATGTGGAGCAGATTCAGAGTGAGATATACAAGAATGGCCCAGTAGAGGGAGCCTTCATCGTCTATGAAGACTTTGTGCAGTACAAGTCCGGTGTGTATCAGCACGTGTCTGGGTCTGCTGTGGGTGGCCATGCCATCAAGATCCTGGGCTGGGGAGAGGAGAATGGTGTTCCCTACTGGCTCTGTGCCAACTCCTGGAACACTGACTGGGGTGATAACGGATTCTTTAAGTTCCTGCGTGGATCGGATCACTGTGGTATTGAGTCTGAGGTTGTGGCGGGGATTCCCAAATAAATTCTATGGTTTTGAGCCAAGATGTCCATTACATATTCAATAGGGGACGGCCCACTCAACTTGCCTGCTCTAGAAAGAACTCGTTTAACAGCTTTTAGACCTTTTTAGTTAAGGCCCACTGATCACCTTGCACACAtggcatgtggttgttgttttttttaaagcacactGGAAAAAACTCCTTTAGGTGGATTAGCAGATgtatcactgttttttttaactgaatgtTTTTTGGGACTGAGCTGTTGTAAGGTCTTGTTCCTTCACCTCCTTAAGGCAAGGTCAATCAAAAAATGTGCACGGGAGGAAATCGTTTTTTAAGATTCATATGAGCATTTCATTTGATCTCAGGTGATTCGAAGCAGACTGTCACTGTTGtagaatttcattttttttattttttttttcccctgttgTCCCTATTCTGCACAAGTGTGGAGCATCTCAAGACTCTGCCCAATGCAGCAGAGGTctgtttttgaatgtttttaatttttaatgatCACAGCTTTcatatttgatatttttattCAACATTACTTCTCTGTGCCACAAATGCCACTCCATAATGTTAGGTACTCATTGTGATTGGTGCCTGTtaccgtttttattttttttatttttagatggTGGATATtggaatgtttttattttctacctGTGTTGATCAAAATATTGGCACATGAAGTGTTATGTtctgaattaaataaaacaatatttggTTCCCAATATGGTGTTGTTACTCTTGAATATCTTGCTGGCATTTGAAATAAATCTTTTTCTGATGGTTTGCACGCCTGATGGAATTGACTCGcagaaaaattaaaattacCAAGAAAATGTGGGCCGAGATACGATTGATGAATGGATAAGTAGATGTGAGTCAAAACTAATCTGATGGTAGTTGATAAATGTTGTAGGTGTCTGCTGTTTCTGACATTTAATCAGACTGTTAATATACTTTTaatccaaaaaggtgtaataaaaaGAATCTGATATACAATAA

Function


symbol description
ctsb Enables collagen binding activity; cysteine-type endopeptidase activity; and proteoglycan binding activity. Involved in several processes, including cellular response to thyroid hormone stimulus; collagen catabolic process; and proteolysis involved in cellular protein catabolic process. Located in extracellular space; lysosome; and perinuclear region of cytoplasm. Colocalizes with collagen-containing extracellular matrix. Implicated in diabetes mellitus. Biomarker of several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); glioblastoma; intracranial aneurysm; and type 2 diabetes mellitus.

NR:

description
PREDICTED: cathepsin B

GO:

id name namespace
GO:0031101 fin regeneration biological_process
GO:0006508 proteolysis biological_process
GO:0050790 regulation of catalytic activity biological_process
GO:0004197 cysteine-type endopeptidase activity molecular_function

KEGG:

id description
K01363 CTSB; cathepsin B

RNA


RNA id representative length rna type GC content exon number start site end site
XM_039794025.1 True 2157 mRNA 0.44 11 30867774 30876711

Neighbor


gene id symbol gene type direction distance location
adpgk2 LOC104966691,LOC103371218 coding downstream 482 30855174 ~ 30867292 (-)
LOC120555418 LOC104920151,LOC107092146,LOC106958996,LOC106906464 coding downstream 40081 30815396 ~ 30827693 (-)
abcb10 abcb10,LOC102798660 coding downstream 182575 30669879 ~ 30685199 (-)
acta1b acta1,LOC102689871,LOC100534413 coding downstream 202514 30661186 ~ 30665260 (-)
ccsapb NA coding downstream 207813 30654191 ~ 30659961 (-)
xkr5b LOC103371226 coding upstream 2230 30878941 ~ 30893299 (-)
eva1a LOC100700039,LOC103371220,LOC101476478 coding upstream 18766 30895477 ~ 30905669 (-)
itsn2b LOC103371221 coding upstream 36660 30913371 ~ 30952594 (-)
LOC120555807 sccpdh coding upstream 88391 30965102 ~ 30974214 (-)
kif26ba NA coding upstream 229300 31106011 ~ 31190077 (-)
G31155 NA non-coding downstream 82546 30782410 ~ 30785228 (-)
G31150 NA non-coding downstream 97965 30769583 ~ 30769809 (-)
G31146 NA non-coding downstream 141420 30699403 ~ 30726354 (-)
G31110 NA non-coding downstream 282318 30569887 ~ 30585456 (-)
G31274 NA non-coding upstream 164837 31041548 ~ 31050491 (-)
G31278 NA non-coding upstream 226097 31102808 ~ 31103063 (-)
G31279 NA non-coding upstream 227059 31103770 ~ 31105588 (-)
G31304 NA non-coding upstream 350508 31227219 ~ 31229674 (-)
G31397 NA non-coding upstream 744505 31621216 ~ 31634058 (-)
fam120b fam120b,LOC104944276 other downstream 335632 30515255 ~ 30532142 (-)
LOC120556497 csmd1,LOC102783723 other downstream 902027 29617320 ~ 29965747 (-)
elp4 elp4,LOC103373817 other downstream 1406538 29402035 ~ 29461236 (-)
prrg4 NA other downstream 1553065 29310550 ~ 29314709 (-)
LOC120555471 hipk3 other downstream 1598591 29217853 ~ 29269183 (-)
cdc42se2 cdc42se2,LOC103398548 other upstream 1231861 32108572 ~ 32117250 (-)
G31602 ddx28,LOC106597432 other upstream 2014788 32891499 ~ 32894405 (-)
wdr76 frmd5,LOC103354945,LOC103374291 other upstream 2465536 33342247 ~ 33353448 (-)
znf710b LOC104936257,LOC102799163,LOC101477128 other upstream 2560100 33436811 ~ 33471335 (-)
serf2 NA other upstream 2689660 33566371 ~ 33569379 (-)

Expression



Co-expression Network