LOC120556157 (chrna7)


Basic Information

Item Value
gene id LOC120556157
gene name chrna7
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053114.1
NCBI id CM020911.1
chromosome length 46923577
location 16260894 ~ 16294060 (-)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039795567.1
TGCTCTCACTCCTCGCTCGGTTCAACATGGACTCACTGAATGTTCTGCTCTTTCTCGCAGTCACCTTCCTCACAGTGAAAGTTTCTCTTCAAGGGCCAGATCAACGCAAACTGTACAACGACCTGATGGCTGGCTACAACCCACTGGTGAGACCAGTCTCCAATGACTCTCAGACTCTCACTGTTCAATTTGGCCTCACCCTCATGCAGATCATGGATGTGGATGAGAAGAACCAGGTTTTGACAACTAACATCTGGCTGCAGCTGCAGTGGGATGATCACTACTGGTGGAATACATCAGAGTATGGAGGTGTGACCAATGTTAGATTTCCTGACCATCTCATTTGGAAGCCAGACATTCTGCTGTATAACAGTGCTGATGAAAGATTTGATGCCACTTTCCACACCAACATTTTGGTTGACTCGTCGGGCACCTGTACCTACTTACCTCCAGGGATCTTCAAGAGCACCTGCTACATCGATGTGCGCTGGTTCCCCTTTGATGTCCAGAGATGTGACCTGAAGTTTGGCTCCTGGACATACGGGGGCTGGTCTCTGGACTTGAAGATGTTGGAGGCGGATATCACCGGCTACATCGCCAACGGAGAGTGGGACCTTGTTGAGGTTCCAGGACGGAAGAACGAGCGTTTCTATGCCTGCTGCGAGGAGCCGTACCCTGACGTCACCTTCACCTTGGTGATGCGGAGACGGACCCTCTACTACGGCCTCAACCTGCTCATTCCGTGTGTGCTGATCTCCACTCTGGCCCTCCTTGTCTTCCTTCTGCCTGCTGACTCTGGGGAGAAGATCTCACTGGGCATTACAGTCCTGCTCTCCCTGACTGTCTTTATGCTGCTGGTTGCAGAGATTATGCCCGCCACATCGGACTCGGTGCCTTTAATAGCTCAATACTTTGCCACTACCATGGTCATTGTTGGCCTCTCAGTAATTGCCACAGTTCTCGTCTTACAATATCACCACCATGACCCTGATGGAAGCAAGATGCCGAAGTGGACCCGTGTGATCCTGCTGAACTGGTGCGCCTGGTTCCTGCGCATGAAGCGCCCAGGTGAGGAGCGAGTGCGTTCAGCCTGTCACAACAAGGCTCCACGGAACAGCCTGACCAGCGTGGAGCTCAATGCAAGCACTTCAGCCTCCCATTCCACCAACGGCAACATGCTTTACGTTGGCATGCGTGGCCTGGAGAGCATCCACTACTCCACAGCTGCCACCTCTTGTGACTCCGGGGTCCTCTGCGGACGGCTGGTTGGACGAGCAGGTGAGGATGAGCTGCTCCTCCCCGCAGGTCACAGCTCCTCAGCTTGCAGAGTGGAACCAGAGCTGGCCAAGATCCTGGATGAGGTGCACTTTATTGCCAAGCGCTTCCGTGACCAAGACGAGGACGAGTTAGTGTGCAACGAGTGGAAATTTGCTGCGTCTGTTATCGACAGGCTTTGTCTCATGGCTTTCTCCCTCTTCACTATCCTCTGCACTATTGGGATCCTCATGTCAGCACCCAACTTTGTAGAGGCCATTTCAAAAGATTTCTTCACTTAAAGGGGAACACCACCCAAATAAAGAATTCATGGCCTAGGAAAGTTCAATCAATGTTTGTGTACATGAGCTACTCCCTGTCAAAGCCAGAAACCAGAGAAGTACAGTAAGTCTCAAACTTGTGATCATTGAGTATGAAGTCTAGAACTGCTCCATAGATAATGAATGAGagaatgatttttctttttttgttatacCCAAATGAGCTTTATTCTATTGTAGTACTcagttctgaaacagaaaatgtaccCATATATTAAAAAGATTCCCCTGGGTGCGGTTACtgtcatctttaacatctttcCCAATTAATTTTCTATGGAGCACTTCTGGACTTTATACTTGATAACATTACAAATTTGAGTTTTAGCCCTCTAGTTTTTATATTTGGGAAAGAGTTGTTCATGTTTGCTAATATTTGTGGACTGTCTTAGACCATAGGAATTACATGTATGAATTCTAAAAAAGGTTTGGAGTTCcccatttaaaggaacacggcgacttattgTGACTcagcgtatcccccagagttagatatgtccata

Function

symbol description
chrna7 Enables several functions, including acetylcholine binding activity; amyloid-beta binding activity; and postsynaptic neurotransmitter receptor activity. Involved in several processes, including negative regulation of amyloid-beta formation; positive regulation of MAPK cascade; and positive regulation of angiogenesis. Acts upstream of or within negative regulation of tumor necrosis factor production. Located in plasma membrane. Part of acetylcholine-gated channel complex. Implicated in schizophrenia. Biomarker of Alzheimer's disease and Lewy body dementia.

NR:

description
PREDICTED: neuronal acetylcholine receptor subunit alpha-7

GO:

id name namespace
GO:0034220 ion transmembrane transport biological_process
GO:0006812 cation transport biological_process
GO:0045211 postsynaptic membrane cellular_component
GO:0030054 cell junction cellular_component
GO:0016021 integral component of membrane cellular_component

KEGG:

id description
K04809 CHRNA7; nicotinic acetylcholine receptor alpha-7

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039795567.1 True 2098 mRNA 0.48 11 16260894 16294060

Neighbor

gene id symbol gene type direction distance location
trip4 trip4,LOC102789106 coding downstream 6289 16168475 ~ 16254605 (-)
gramd2aa gramd2,LOC102079700,LOC101472756 coding downstream 192359 16031670 ~ 16068535 (-)
myo9aa myo9a coding downstream 243182 15887011 ~ 16017712 (-)
scamp2l scamp2,LOC106512987,LOC107381771 coding downstream 376296 15872711 ~ 15884598 (-)
bbs4 bbs4,LOC102786181 coding downstream 388453 15856715 ~ 15872441 (-)
itga11a itga11 coding upstream 125803 16419863 ~ 16492643 (-)
anp32a anp32a,LOC104942769 coding upstream 251966 16546026 ~ 16551698 (-)
LOC120555746 tle3,LOC103353191 coding upstream 655581 16949641 ~ 16983198 (-)
uacab uaca coding upstream 813413 17107473 ~ 17172469 (-)
LOC120556297 LOC103353194,LOC104949848 coding upstream 879826 17173886 ~ 17185740 (-)
G27698 NA non-coding downstream 92473 16166959 ~ 16168421 (-)
G27659 NA non-coding downstream 231722 16028887 ~ 16029172 (-)
LOC120555431 NA non-coding downstream 412195 15818610 ~ 15848699 (-)
G27594 NA non-coding downstream 664027 15596613 ~ 15596867 (-)
G27587 NA non-coding downstream 714103 15546578 ~ 15546791 (-)
G27725 NA non-coding upstream 92836 16386896 ~ 16387172 (-)
G27729 NA non-coding upstream 115410 16409470 ~ 16409936 (-)
G27767 NA non-coding upstream 263473 16557533 ~ 16558521 (-)
G27768 NA non-coding upstream 264578 16558638 ~ 16559005 (-)
G27775 NA non-coding upstream 344857 16638917 ~ 16642809 (-)
LOC120556162 znf609 other downstream 101012 16071569 ~ 16159882 (-)
cfap70 LOC103368539,LOC102222702,LOC102790175,LOC102296598,LOC102204478,LOC104922799 other downstream 1182064 15050662 ~ 15078830 (-)
G27420 NA other downstream 1416989 14842713 ~ 14843905 (-)
LOC120556476 NA other downstream 1680883 14578027 ~ 14580011 (-)
G27321 NA other downstream 1790549 14469758 ~ 14470345 (-)
LOC120555730 adamts7 other upstream 27903 16321963 ~ 16408868 (-)
LOC120556401 LOC104927750,LOC104949847,LOC103353195 other upstream 899453 17193513 ~ 17284509 (-)
G27925 LOC103353204,LOC106512954,LOC102223374,LOC104951141 other upstream 1214063 17508123 ~ 17513168 (-)
c3h15orf48 clg1h15orf48,csgr07h15orf48,LOC103353210,LOC107085327,LOC104951152 other upstream 1305690 17599750 ~ 17601390 (-)
G28121 NA other upstream 1924062 18218122 ~ 18220550 (-)

Expression


Co-expression Network