kars1 (kars,LOC102775760)


Basic Information

Item Value
gene id kars1
gene name kars,LOC102775760
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053114.1
NCBI id CM020911.1
chromosome length 46923577
location 25931276 ~ 25942831 (+)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039795652.1
ACAAGCCGTTTTTTGTGGTACACTTTGGATATACTTTTGTTGTGTGAAGTATTCTTCTACTCTCTTTCTGAGTCTTCTGATTTCCGACAGTCAACCAAACGCACCATCAAGTTCTCGCGTTTTTGCGGTGCTTGCGCGACGGTTGATCTTTCTGAGCGCAGCATCTACAACATGGCTGACGTTACAGCGGTAGAAGAAGAGAAACTCAGCAAAAAGTCTGTCTGCTGACTGTGGTAGCTCAGCATGCTGTGTCTGGTCAGGGCAGCCAGGCAGCAGCTGTGCCAACTTGCCTTTGGGGTCAGGGGACAGTGGTTAAAATGTGCACCCCCATGTACAACTGCAGTCCCTGCTCAAATGTACGGGATCCGTTGGAGAGGTGACAAAAGTGAGCTGAAGAGACGAATGAAAGCTGAAAAGAAGGCGGCCGAGAAAGAAGCCAAGGTCAAAGAGCAGGTGGAGCAAAAGCAGGAATCCAATGACCAGGCGGCACAAAATGCCTGTGGGTTGGATGAGGAGACACTTGACCCAAATCAATATTACAAGATCCGCACCCAGGCCATTGAGGACCTGAAGGGCACAGCAGAGGACCCCTATCCTCACAAGTATCATGTAGACTTGTCACTTACAGAGTTCATCGAGAAATACAATAATCTACAACCTGGAGACCAGCTGACGGACGTTGTTCTCAATGTGTCAGgCCGCGTCCATGCAAAGAGGGCTTCTGGTGCCAAGCTGATTTTCTACGACCTGCGAGGTGAAGGCGTCAAGTTGCAAGTCATGGCAAACTCAAGGAGCTACAAGTCTGAGGAGGCCTTTGTAGCCATCAACAACAAACTGCGGCGCGGTGATATTATCGGTGTTCGCGGTAACCCAGGGAAGACCAAAAAAGGGGAGCTGAGCATCATTCCCATCGAGATGACCCTACTATCACCATGTTTGCACATGTTGCCCCACCTCCACTTTGGCCTCAAAGACAAGGAAACACGATTTCGCCAACGCTACTTGGATCTGATTCTCAATGACTACGTGAGACAAAAGTTTATAACTCGCGCCAAAATCATCACATACCTGCGCAGCTTCCTGGACCAGCTGGGCTTTTTGGAGATTGAGACACCAATGATGAACGTTATTCCTGGTGGAGCAGTGGCCCGTCCATTTGTTACTTACCACAATGAGCTGGATATGAACCTGTACATGAGGATTGCTCCTGAGCTCTACCACAAGATGCTCGTGGTTGGTGGAATAGACAGAGTGTATGAGATTGGTCGTCAGTTCAGGAATGAAGGCATCGATCTCACTCACAATCCAGAGTTCACCACCTGTGAATTCTACATGGCATATGCTGATTACCATGACTTGATGGAAATCACAGAGAAACTACTCTCAGGAATGGTGAAGCACATCACTGGAGGATACAAGGTGACTTATCACCCTGATGGTCCGGAGGGACAGGCCTGTGAGATTGACTTCACGCCGCCATTCAGGAGAGTAAGCATGACGCACGACCTGGAGAAGATTATGGGAGTGAAGTTCCCGCCTGCTACCAGCTACGACAGTGATGAGACGCGTGCATTCTTTGACAAGCTTTGTGCACAGAAAGGAGTTGAATGTCCTCAACCCCGAACCACTGCCCGCCTCCTTGACAAGTTGGTTGGAGATTTCCTTGAGGTCACCTGCATCAACCCCACATTCATCTGTGATCACCCTCAAATCATGAGTCCCTTAGCAAAATGGCACAGATCAGAGAAAGGCCTAACGGAGCGTTTCGAGCTCTTTGTGATGAAGAAGGAAATCTGCAATGCTTACACTGAGTTGAATGATCCAATAAGACAGAGACAGCTTTTCGCACAGCAAGCCATGGCCAAAGCTGAGGGTGATGATGAAGCCATGTTCGTTGATGAGACCTTCTGCACAGCTCTGGAATACGGACTGCCACCAACTGCCGGCTGGGGCATGGGCATCGATCGTCTCACCATGTTCCTCACTGACTCCAACAACATCAAGGAGGTGTTGCTCTTCCCAGCCATGAAGCCCGACGACAATAAGACCTCAGCGCCCACAGAGGGCACCTCTGTCTAATGacatgacctctgacctctcctGCTATCTGATCTGTGCAGGAGTCCGTATGGAGTAGGAGCCCTGACCTCACTTTGGTCATCAGTGGAGCTTACAGGTTCTGTCTTTTATTAATTAGTTAGTCTGTCAAATGTTTGATTCTTGCTGTCATTAAGGGAAATCATCTTCTCAGTTATATGGTTGGCTGATAAACGATGActaatgcttcttttttttttttttttttcttttgtatttcttACACTTTTGCCATCATATTTGCCACGTCCTCCTTGTTTGATGTAAGGAGACATTTTAATCCTTGGTGTCATCTAGACCGTAAATCAATGGTGTTTGATCAGAAAGTCATGCGTGATCTGCTGTTCTATGCAAACTTGGATAATATTTTTGAATATACTTTGAGATACTTCATGGGGGGCTTTATTCTGGCTACTAAATACAGAGTAGATAACCACATAACAAAGTTAAAGAACCTCTAATATTTTTAAGTATATTCATCCGTTTTTACCAGGTGTGCTTATATTCTGTCTGAGACTTTTCATAGACTCCATACATTACGTACTCCTCTGCGAAGATGTTTAAACATGGGTATGTCTGAATAAAGTACATATGAATCAACA
>XM_039795653.1
AAGCCGTTTTTTGTGGTACACTTTGGATATACTTTTGTTGTGTGAAGTATTCTTCTACTCTCTTTCTGAGTCTTCTGATTTCCGACAGTCAACCAAACGCACCATCAAGTTCTCGCGTTTTTGCGGTGCTTGCGCGACGGTTGATCTTTCTGAGCGCAGCATCTACAACATGGCTGACGTTACAGCGGTAGAAGAAGAGAAACTCAGCAAAAATGAGCTGAAGAGACGAATGAAAGCTGAAAAGAAGGCGGCCGAGAAAGAAGCCAAGGTCAAAGAGCAGGTGGAGCAAAAGCAGGAATCCAATGACCAGGCGGCACAAAATGCCTGTGGGTTGGATGAGGAGACACTTGACCCAAATCAATATTACAAGATCCGCACCCAGGCCATTGAGGACCTGAAGGGCACAGCAGAGGACCCCTATCCTCACAAGTATCATGTAGACTTGTCACTTACAGAGTTCATCGAGAAATACAATAATCTACAACCTGGAGACCAGCTGACGGACGTTGTTCTCAATGTGTCAGgCCGCGTCCATGCAAAGAGGGCTTCTGGTGCCAAGCTGATTTTCTACGACCTGCGAGGTGAAGGCGTCAAGTTGCAAGTCATGGCAAACTCAAGGAGCTACAAGTCTGAGGAGGCCTTTGTAGCCATCAACAACAAACTGCGGCGCGGTGATATTATCGGTGTTCGCGGTAACCCAGGGAAGACCAAAAAAGGGGAGCTGAGCATCATTCCCATCGAGATGACCCTACTATCACCATGTTTGCACATGTTGCCCCACCTCCACTTTGGCCTCAAAGACAAGGAAACACGATTTCGCCAACGCTACTTGGATCTGATTCTCAATGACTACGTGAGACAAAAGTTTATAACTCGCGCCAAAATCATCACATACCTGCGCAGCTTCCTGGACCAGCTGGGCTTTTTGGAGATTGAGACACCAATGATGAACGTTATTCCTGGTGGAGCAGTGGCCCGTCCATTTGTTACTTACCACAATGAGCTGGATATGAACCTGTACATGAGGATTGCTCCTGAGCTCTACCACAAGATGCTCGTGGTTGGTGGAATAGACAGAGTGTATGAGATTGGTCGTCAGTTCAGGAATGAAGGCATCGATCTCACTCACAATCCAGAGTTCACCACCTGTGAATTCTACATGGCATATGCTGATTACCATGACTTGATGGAAATCACAGAGAAACTACTCTCAGGAATGGTGAAGCACATCACTGGAGGATACAAGGTGACTTATCACCCTGATGGTCCGGAGGGACAGGCCTGTGAGATTGACTTCACGCCGCCATTCAGGAGAGTAAGCATGACGCACGACCTGGAGAAGATTATGGGAGTGAAGTTCCCGCCTGCTACCAGCTACGACAGTGATGAGACGCGTGCATTCTTTGACAAGCTTTGTGCACAGAAAGGAGTTGAATGTCCTCAACCCCGAACCACTGCCCGCCTCCTTGACAAGTTGGTTGGAGATTTCCTTGAGGTCACCTGCATCAACCCCACATTCATCTGTGATCACCCTCAAATCATGAGTCCCTTAGCAAAATGGCACAGATCAGAGAAAGGCCTAACGGAGCGTTTCGAGCTCTTTGTGATGAAGAAGGAAATCTGCAATGCTTACACTGAGTTGAATGATCCAATAAGACAGAGACAGCTTTTCGCACAGCAAGCCATGGCCAAAGCTGAGGGTGATGATGAAGCCATGTTCGTTGATGAGACCTTCTGCACAGCTCTGGAATACGGACTGCCACCAACTGCCGGCTGGGGCATGGGCATCGATCGTCTCACCATGTTCCTCACTGACTCCAACAACATCAAGGAGGTGTTGCTCTTCCCAGCCATGAAGCCCGACGACAATAAGACCTCAGCGCCCACAGAGGGCACCTCTGTCTAATGacatgacctctgacctctcctGCTATCTGATCTGTGCAGGAGTCCGTATGGAGTAGGAGCCCTGACCTCACTTTGGTCATCAGTGGAGCTTACAGGTTCTGTCTTTTATTAATTAGTTAGTCTGTCAAATGTTTGATTCTTGCTGTCATTAAGGGAAATCATCTTCTCAGTTATATGGTTGGCTGATAAACGATGActaatgcttcttttttttttttttttttcttttgtatttcttACACTTTTGCCATCATATTTGCCACGTCCTCCTTGTTTGATGTAAGGAGACATTTTAATCCTTGGTGTCATCTAGACCGTAAATCAATGGTGTTTGATCAGAAAGTCATGCGTGATCTGCTGTTCTATGCAAACTTGGATAATATTTTTGAATATACTTTGAGATACTTCATGGGGGGCTTTATTCTGGCTACTAAATACAGAGTAGATAACCACATAACAAAGTTAAAGAACCTCTAATATTTTTAAGTATATTCATCCGTTTTTACCAGGTGTGCTTATATTCTGTCTGAGACTTTTCATAGACTCCATACATTACGTACTCCTCTGCGAAGATGTTTAAACATGGGTATGTCTGAATAAAGTACATATGAATCAACA

Function

symbol description
kars Enables several functions, including ATP binding activity; lysine-tRNA ligase activity; and tRNA binding activity. Involved in several processes, including ERK1 and ERK2 cascade; diadenosine tetraphosphate biosynthetic process; and lysyl-tRNA aminoacylation. Located in cytosol and nucleus. Part of aminoacyl-tRNA synthetase multienzyme complex. Biomarker of sciatic neuropathy. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease recessive intermediate B and autosomal recessive nonsyndromic deafness 89. Orthologous to human KARS1 (lysyl-tRNA synthetase 1).

NR:

description
lysine--tRNA ligase-like isoform X1

GO:

id name namespace
GO:0006430 lysyl-tRNA aminoacylation biological_process
GO:0005737 cytoplasm cellular_component
GO:0005524 ATP binding molecular_function
GO:0004824 lysine-tRNA ligase activity molecular_function
GO:0003676 nucleic acid binding molecular_function

KEGG:

id description
K04567 KARS, lysS; lysyl-tRNA synthetase, class II

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039795652.1 True 2699 mRNA 0.47 15 25931276 25942831
XM_039795653.1 False 2526 mRNA 0.46 14 25931278 25942831

Neighbor

gene id symbol gene type direction distance location
dkk3a dkk3 coding upstream 120772 25805445 ~ 25810504 (+)
btbd10b btbd10,LOC103362377 coding upstream 280663 25639529 ~ 25650613 (+)
ctr9 ctr9 coding upstream 514490 25407601 ~ 25416786 (+)
ampd3a LOC104930104 coding upstream 575423 25326246 ~ 25355853 (+)
adma NA coding upstream 595797 25332984 ~ 25335479 (+)
gcshb gcsh coding downstream 10967 25953798 ~ 25957807 (+)
rpl13 rpl13 coding downstream 18087 25960918 ~ 25966638 (+)
LOC120556589 NA coding downstream 21848 25964679 ~ 25964758 (+)
LOC120556588 NA coding downstream 23346 25966177 ~ 25966255 (+)
cpne7 cpne7 coding downstream 29102 25971933 ~ 26003635 (+)
G29922 NA non-coding upstream 1303 25929747 ~ 25929973 (+)
G29915 NA non-coding upstream 68885 25861728 ~ 25862391 (+)
G29868 NA non-coding upstream 243168 25685840 ~ 25688108 (+)
G29851 NA non-coding upstream 294151 25624948 ~ 25637125 (+)
G29849 NA non-coding upstream 308824 25622189 ~ 25622452 (+)
G29964 NA non-coding downstream 62432 26005263 ~ 26006950 (+)
G29974 NA non-coding downstream 115097 26057928 ~ 26059434 (+)
G29975 LOC103361962,LOC107659108,LOC101069992,LOC107565377 non-coding downstream 118360 26061191 ~ 26063421 (+)
G30003 NA non-coding downstream 175334 26118165 ~ 26118521 (+)
G30006 NA non-coding downstream 221745 26164576 ~ 26164930 (+)
nfat5b nfat5 other upstream 3550 25883454 ~ 25927726 (+)
pkd1l2a vat1l,pkd1l2,LOC102776808 other upstream 47916 25855839 ~ 25883360 (+)
sox6 sox6,LOC103363464 other upstream 1475588 24320064 ~ 24455688 (+)
plekha7b NA other upstream 1616631 24235723 ~ 24314645 (+)
G29433 NA other upstream 2198805 23727012 ~ 23732471 (+)
LOC120556198 LOC103371916,LOC104965843 other downstream 1352926 27295757 ~ 27316181 (+)
nedd4a nedd4,LOC103371920,LOC102785817 other downstream 1375539 27318370 ~ 27351837 (+)
LOC120555577 NA other downstream 1466209 27409040 ~ 27410250 (+)
vrk3 NA other downstream 1483457 27426288 ~ 27440414 (+)
LOC120555924 LOC103398348,LOC104965831,LOC103374185 other downstream 1513585 27456416 ~ 27464759 (+)

Expression


Co-expression Network