erbb3a (erbb3)


Basic Information

Item Value
gene id erbb3a
gene name erbb3
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053115.1
NCBI id CM020912.1
chromosome length 44863486
location 15879790 ~ 15899901 (+)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039798378.1
TGTAAAGTTACGGCTcagtaaaatatcagaaaaggGAATACACGAACAGGTTTTCACTACAGCACGGATTTACTTCTTCATTTGAATACTAGAAGAAAGCAAAGGAAATAAATAAGAAAGGGAATCTGGATTAACTCAACAACGTTTCTAAATGGACTCTCTTGGATTGAAACCACCGAGAACCATTTATTATGAGACAAGGACACGCTTCTTATTAATGTGATGGCAATTTTTGTTTGAAACGTCACCATCTTGGGAATTTGAGTGAGGATGACCGCCCTCATGAGGAAGGTGCAACAAGTGCTGTGCGTCCTGCTGCCATGCGCTCTTCAACTCTGCAGCGCACAGACACAAGGAGTGGTTGTATGTTCCGGCACCCACAATGGTCTGAGCACGACAGGAAATTCAGAGGTCCAGTACAACTTGATGAAAGAGATGTACACCGGCTGTGAGATTGTGATGGGCAATCTTGAAATTACCATGATGGAGCACACCAGAGACTTCTCCTTCCTGCAGTCTATCAGGGAGGTGACAGGCTACATCCTTTTAGCCGTCACCGAGTTCAGCCGTCTGCCTCTGGACCGCCTGCGCGTCATCAGAGGTACCACGCTGTATGAGGACCAATACGCTTTGGCTGTGATGCTCAACTACCAGAAGGACGGACAGCATGGCCTTCAAGAACTGGGCCTGACACACCTCACAGAGATACTGGAAGGAGGAGTCAAGATCATCCAGAATAAGTACCTGAGCTACGCCCCGCAGGTGAACTGGCAGGACATAGTGAAGGATGGAACAGCTCATATTATGTTCGAAGGCAATGGGCTTGAAAAGCCTTGTAACAAAGCATGTGGAGACCTTCCATGTTGGGGTCCAGGAAATGACACTTGCCAGATCTTGACAAAGACTGTGTGTGCCCCTCAGTGTAACAGCCGATGCTTTGGTAGAAACCCGAGCGACTGTTGTCACAGTGAGTGTGCCGGAGGCTGCTCTGGAGCCCTGGATACAGACTGCTTTGCTTGCAGGAACTTCAACAACTCTGGCgcctgtgtgcctctgtgtcccCAGACCATCATCTACAACAAGCACACATTCAAAATGGAGCCCAACCCCAATGCCAAGTACCAGTATGGCTCCATCTGTGTGGCCCAGTGCCCCActaatTTTGTGGTGGATGGCAGCTCATGTGTGAGCAATTGCCCGTCTGATAAAATGGAGGTGGAGAAAAACGGAGTGAAAAGTTGTGAACCCTGTGGAGGCCTCTGTCCTAAAGCTTGCCATGGCACAGGAAGTCCAACCAGACAGACTGTAGATGCTCTTAACATTGACAGTTTCATAAACTGCACTAAGATCCAGGGCAGTCTGCACTTCCTGGTGACTGGTATCAAAGGTGATGATTACAACAATGTACCAGCCCTCGATCCAGAGAAACTGAAAGTCTTCAACACTGTGAGGGAGATTACAGATATCCTCAGTATACAGTCATGGCCTAAAAACATGCCTGACCTGTCAGTCTTCTCCAACCTCCAAACAATTCAGGGCAGAACACTTTACAAAGCAGTGACTTCTAAAAGGGGCTACTCTCTTCTGGTGATGAAGATCCCCTCTTTGACCTCCATGGGGTTACGCTCACTACAAAAAATAAACGACGGTGGCGTCTACATCACAGGAAACAAGAAGCTCTGCTACTATGACACTGTTAACTGGACGCGTATCATGACCAGCAACTCTCGCCCGCAGCGACGCCAGAAGAACATCGACCTCAAGGAGAACAGACCAATAAATCAGTGTGTTATTGAGGGCCATGTATGTGACCCCCTGTGCTCTTCTGATGGCTGCTGGGGCCCGAGGCCAAACCAGTGTCTGTCTTGTAAGAAATACAGCAGGGAAGGAACGTGCGTGCCAGACTGCATGTTCTTAACTGGGGAGAGGCGGGAGTTTGCTACTCAATCAGGAGAGTGTATGGCATGCCACCCTGAGTGTAAGGTCCAGGAGGGGAAGCAGACCTGCACAGGCCCGGGAGCAGATCAGTGTGTAGCATGTGCCAGGTTGCAGGACGGTCCACACTGTGTCTCCTTGTGTCCTGAGGGCGTGATGGGAGGGGACGAGGTCATCTTTAAATACCCCAACAAGCAAGGCAGCTGTGAAACATGCCACATCAACTGCACCCAAGGGTGCTACGGCCCAGGAATTGGAGACTGTGTGGGGTCATCTCGGTACATTTCTGGACAAGCGACCACAGCCATCGTACTGGGAGTGATTGCCATCCTCTTCGCTTCATTCTCTGTTTTTGCGCTGACTGTTCTGTACCGCCGAGGCCTTGCCATCCGTCGCAAGCGAGCCATGAGGAGATACATGGAGAGCGGAGAGAATTTTGAGCCTCTGGATCCTGGAGAGAAAGGGTCTAAAGTCCACGCTCGGATCTTAAAGCCCACAGAGCTGCGTAAGATCAAGCTCAATGGTAGTTTTTTAATAAGTCTGTCTGTAAATCTCTTTCTTATTTCACAGGGCATTTGGATCCCTGAGGGCGATACAGTGAAGCTTCCTGTGGCCATAAAGACTATTCATGATCGCTCCGGACGGCAGACCTTCTATGAGCTTACAGAACACATGATGACCATTGGAAGCATGGACCACATTAACGTTGTCAGGACCCTGGGTATCTGTCCCGGTGCCAGCCTGCAGCTCGTCACTCAGCTCAGCAGTCAGGGCTCTCTGCTGGAGCATGTCAGgaacagcaaaaacaaactgagccCGCAAAGGCTGCTCAACTGGTGTGTTCAAATCGCAAAGGGTATGTATTACCTGGAGGAGAACAAAATGATCCACAGGAACCTCGCTGCCAGAAATGTGCTCCTGAAGAATAATTACACCGCCCAGATCTCAGACTATGGCATTGCAGACCTACTTTACCCTGATGACAAGAAGTGCTTTTACAATGAGGTCAAGACACCAATCAAATGGATGGCCTTAGAGAGCATCATGTttcgcagacacacacatcagagCGATGTCTGGAGTTACGGTGTGACGGTATGGGAGATGATGTCCTATGGGGCAGAGCCGTATACTACGATGCGTCCACAGGACGTTCCTGATCTGCTGGAAAAGGGCGAGCGTCTGTCCCAGCCTCAAATTTGCACCATTGATGTCTACATGGTCATGGTTAAGTGTTGGATGATTGATGAGAATGTCCGTCCAACATTCAAAGAGCTGGCGAATGAATTTACCAGAATGGCCAGAGACCCGCCTCGCTACCTGGTGATCAAAGAGGACTGCAGCCAACAGGACTCGGCCCCGGATGAACTGGCCCAGCGGAGTGCAGACCTGGACGACCTGGCTGATCTAGACATTGAGCTAATggacaaggaggaggagggggtggtaGATGGTATGACTCCAGCCCCCCACTACTTGTCTCAGGCCAGAAGCTTTAGTCGCCTCTCCAGGATGGACACGCACAGAGTGGTTATTACTTCATCAAACCTGGCTGGATACCTGCCTATGACCCCAGGTGTTGACAACCCAGGACAGGCCATGTGGCAGTCGCGCTCTCGACTAAACTCGGCCCGCACTGTGTCTGAGAGCTCAGAGGGCTGCGGCACAGCAGTGGAGCTGGAGATGAGTGAGGACTTTTCCCTGACAGGGAGCCTGAAGAGACGACGTCAACGTGAGGACAGCGCTTACATATCGCAGAGGGACAGCTTGTCCGGCGGGCCACCAGAGACTCCATCACCAGATATGGAGGAAGAGGACCAGAATGGATACGTGCTTCCTGGAGACAGCCCAGAGAGAGatACCCTACTTTCCTCTCGAGCCTCTCCTGGCAGGATGGGCAAGTCTCATTCATCGGGCCTCCTCATTGACCCAGATGAGGAAGAATATGAGTACATGAACAAGCAGACATGTCTGACAGCTGTCTCACCCAGGCACAGCAGCCACTGGCCGAAGCCGAACAAGAAGCGCACCTCCTCTGTATCGTCAGCAGTGACAGCATGCTCTGGTGACACCACATCATCTGTGGAGGTCAGGGGAGGTCACACACTGAGCAATTACTACTCTGATTCAGAGCAGCAGGAATCTAATGAAGTTGAATATGAATACATGGACATCAGGGGTGAAAAAGATAAATGCCCTCCAGTGCCTGACCCTCCTCCGACTCCTACACCAGCAAGGATGGGcagagaggtggaggaggaggaggaggaggaagaggaggaggaatatGTGGACGACAGTAACTACCATTACACAAACAGACAGCCAAAGCTGCGTCAAGCTCTTCGAGACAGGAAGGAGCTGAAGATAGAAGGAGGGGACGAAGGTGAGGCGTATGAGTATGAGGACATGGACTCCTTTGCTGCCCTGCGGCCTGGAGATTCTGTGGTGTACCACAACCtgcagagggagggggagggagcaGTAGGGGGCACAGAGGCACATCGATCTGGCTTTGAGTCCTATGTAAAAGTGCGAGCTGGAGTCGGGGAACCTGCAGCTGGCGACAGATCTTTTGACAATCCAGACTACTGGCACAGCAGGATGTTTCTGAAGCCCAAAGCAGTGCCTACATGAGGAACATTTTAAATCTCACGAACTTTCCTCTGAGACATATTCATGAAGGACCTGAAACAGGAAATGCAATCAAAGCCATGTTAATAATGTAGCCTATGACACCCAGCATGTGTGACTTTTTTACACCTTTGTTTACTGTTACAGGCTGACGTTAGGTCTTGTATTTAGGCCTATGATTTTAGGGCATTTCCAGAAATAATAGCACTGAGTGTTGAAAACACTAACAGAAATGAACAGATTACAAGCTATATTTTTCTGTTTACATTCTGAAAATGAACAAAGCTTTTCTTGAACAAA

Function

symbol description
erbb3 Enables several functions, including ErbB-3 class receptor binding activity; neuregulin binding activity; and protein heterodimerization activity. Involved in several processes, including extrinsic apoptotic signaling pathway in absence of ligand; phosphatidylinositol 3-kinase signaling; and positive regulation of protein tyrosine kinase activity. Located in basolateral plasma membrane and extracellular space. Part of ERBB3:ERBB2 complex. Implicated in lethal congenital contracture syndrome 2; lung adenocarcinoma; and lung non-small cell carcinoma. Biomarker of carcinoma (multiple); ductal carcinoma in situ; prostate cancer; and urinary bladder cancer.

NR:

description
PREDICTED: receptor tyrosine-protein kinase erbB-3

GO: NA

KEGG:

id description
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039798378.1 True 4869 mRNA 0.50 29 15879790 15899901

Neighbor

gene id symbol gene type direction distance location
arf3b arf3,ARF3,arf3a,LOC102781726,LOC106921537,LOC106954774,LOC104956878 coding upstream 2930 15871718 ~ 15876860 (+)
LOC120557571 ikzf4 coding upstream 20019 15851997 ~ 15859771 (+)
LOC120556934 LOC104941416,LOC101064200 coding upstream 45856 15824383 ~ 15833934 (+)
ankrd33ab LOC103367911 coding upstream 56225 15818623 ~ 15823565 (+)
b4galnt1b b4galnt1,LOC104942127 coding upstream 89885 15772189 ~ 15789905 (+)
pa2g4a pa2g4,LOC104933448,LOC102793326 coding downstream 3599 15903500 ~ 15913619 (+)
vhl vhl,LOC104941408 coding downstream 42863 15942764 ~ 15945552 (+)
tatdn2 NA coding downstream 48548 15948449 ~ 15960280 (+)
LOC120558102 LOC104943766 coding downstream 91833 15991734 ~ 16011506 (+)
prkcda prkcd,LOC104933455 coding downstream 117078 16016979 ~ 16034962 (+)
G38885 LOC104942130 non-coding upstream 117475 15760792 ~ 15762315 (+)
G38852 NA non-coding upstream 124731 15673979 ~ 15755059 (+)
G38860 NA non-coding upstream 150390 15727979 ~ 15729400 (+)
G38858 NA non-coding upstream 157606 15718996 ~ 15722184 (+)
G38832 NA non-coding upstream 235391 15644061 ~ 15644399 (+)
G38948 NA non-coding downstream 14638 15914539 ~ 15914901 (+)
LOC120557201 NA non-coding downstream 19484 15919385 ~ 15921622 (+)
G38966 NA non-coding downstream 84723 15984624 ~ 15985096 (+)
G39052 LOC101067125,LOC103386161,LOC103365890 non-coding downstream 295478 16195379 ~ 16195784 (+)
G39076 LOC104930492,LOC103358728,LOC102300171,LOC101465142 non-coding downstream 335113 16235014 ~ 16251725 (+)
G38834 NA other upstream 231939 15645511 ~ 15647851 (+)
calcoco1b LOC104959845,LOC103376572 other upstream 1005331 14865059 ~ 14874459 (+)
znf740a LOC107385642,LOC101469799,LOC102214350,LOC102304359,LOC103376569,LOC107082105,LOC100709046 other upstream 1022721 14765297 ~ 14857069 (+)
G38517 NA other upstream 1063354 14808352 ~ 14816436 (+)
cdk4 LOC107684003,LOC107701179 other upstream 1122431 14740609 ~ 14757359 (+)
crbn crbn,LOC102793823 other downstream 23420 15923321 ~ 15937097 (+)
ccdc174 ccdc174 other downstream 65501 15965402 ~ 15974237 (+)
eefsec eefsec,LOC102787825 other downstream 149777 16049678 ~ 16060330 (+)
LOC120557902 rab7,rab7a,LOC102230535,LOC106583206,LOC105017191,LOC101061812 other downstream 249224 16149125 ~ 16158362 (+)
G39104 LOC103385912,LOC104930488,LOC103358732,LOC101079922 other downstream 533337 16433238 ~ 16435229 (+)

Expression


Co-expression Network