vhl (vhl,LOC104941408)


Basic Information

Item Value
gene id vhl
gene name vhl,LOC104941408
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053115.1
NCBI id CM020912.1
chromosome length 44863486
location 15942764 ~ 15945552 (+)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039798752.1
TTGACGTCCAGGGACTCTCAACTCAACCGGAAGagtaaatgtaaacaaagtagTTGAGATTTAAAAAAGTACAGTAGACTGTTCTCTCCTAGTGTTACTGAAACAGTTgcttgtattacatttttttttataaacgaTGTAATCTAATAAACGTTAGACAGACTAAGTGCTAAACCTATTGATTCAACGAACTCCATTTGTCGACAACATGGATTTCTTGCCATCTTgctgctagctagcgttagctaaacGGCTAATCTCACTGCGCTAACCATTAGCTAAGCGTTAATAAGCGACCAGCACCAATGCCTCAAGAGGGAGAACAGTCTCTTCCCCTGGTTCGCTCCCTGAACAGTCGAATACCGATTAAAGCTGTGTTTCGTAACCTCAGTCCCCGTGTCGTACGACCACTATGGATAGATTACCGCGGAGAACCCCGGGCGTACGTTGATTTACAGCCAGGAACGGGACGAGAAATGTCGACCTTTATCGGTCACCCATGGATGTTCAGAGATGCAGAGACTGATGAGCCACTGAGAGTGAACTGCAAAGAACTGTATCTTCCTAAACCAGCAGAGGGTAGAAATGCTATTATCACTTTACCAGTTTACAGCCTCAAGGATCGTGCTCTTCAGGTTATTCGGCGTCTGGTACGAGCAGAAGACTACAGGAGGTTGGAAATAGCACGGTGTCTCCACGAGGAGCTGGAAGATCTGCCCAATGTATTGAAAGATCTGCACCGCATGAACCAGCGGGTAGAGCAGCATCTGCTGGAGAGGATCCATTGCCAGGAGGAATGAGGCATGAAACTGGATGGATAATGGTCTCATATAGACAGCAATATTATATTCCACACTATTAGAAAGCACAGAAGCCAGAATTAATGAAATATAAGATACAACGTTGGAATTACTTCTTGGGTGAGTGAGCAGCTGTTGCAAAGACTTCCCTAGAGGTCTTACATTTGCTGCAAAGGAGTTTGATCTGCTGCCTGTTATATTCACTCATTGGCTTTGGCAAATGTCTTCccttgcagaaaaaaaactgtatgtaGCATTTACCTTTTAGGACAAGGAGTGTTCAGTTCATCTTCAGTTAAATAGTATTGTTTAACCTCTAAAATGGTATTTAAGGATTTGTTTAAGGAAGGTTTATTCCTAAAAGGCAATTAGAGAAATTTTTGTTATTGATGCCTATCTGATTATGTTACTCTCTACTTTATTTTGCCATATCGCCAGGTTCTGGCCTAAAATCCTATTCGATCATATGCACAAGACAGATCTTACAGTACAACTATGTTTTTGTCATGCATGCAGTGTTATAACTGCTCTTCTGTCCTAAATATCATGTTATAAAGGAGACTAAATAAAAAGTATATAGTCACATTAGATAGGAATTTCAGAGAGATATGTGTTGTTAATATTCTTATTGGGAATGCCTGAGATAAGGTGATCTTAACCAATTCAGTTTACTGCACCTCTCCCCTCAAAAAACATCTTACTTTGTTATTCTAGCAGTTTAAAGACTGAACTTTTCAGCAATCATCATAAAGCTTTTGCTTTGGCACTTGAAATCTGAAAAACATGGAGTGATTATGGGTGTATTTTCCAAGTTGTCCTATTCTGGTGAATGTAGACTTTTTGTCAGAATATACCTACCACCATAAATTGACCGAGTCTCTTCTAA

Function

symbol description
vhl Acts upstream of or within several processes, including hemopoiesis; pronephric duct development; and regulation of vascular endothelial growth factor receptor signaling pathway. Predicted to be part of VCB complex. Predicted to be active in nucleus. Is expressed in several structures, including lateral mesoderm; liver; nervous system; otic vesicle; and pleuroperitoneal region. Used to study clear cell renal cell carcinoma; familial erythrocytosis 2; and von Hippel-Lindau disease. Human ortholog(s) of this gene implicated in several diseases, including pancreatic cancer (multiple); pheochromocytoma; polycythemia (multiple); renal cell carcinoma; and von Hippel-Lindau disease. Orthologous to human VHL (von Hippel-Lindau tumor suppressor).

NR:

description
von Hippel-Lindau disease tumor suppressor

GO:

id name namespace
GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway biological_process
GO:0045765 regulation of angiogenesis biological_process
GO:0030218 erythrocyte differentiation biological_process
GO:0016567 protein ubiquitination biological_process
GO:0005634 nucleus cellular_component

KEGG:

id description
K03871 VHL; von Hippel-Lindau disease tumor supressor

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039798752.1 True 1686 mRNA 0.40 3 15942764 15945552

Neighbor

gene id symbol gene type direction distance location
pa2g4a pa2g4,LOC104933448,LOC102793326 coding upstream 29145 15903500 ~ 15913619 (+)
erbb3a erbb3 coding upstream 42863 15879790 ~ 15899901 (+)
arf3b arf3,ARF3,arf3a,LOC102781726,LOC106921537,LOC106954774,LOC104956878 coding upstream 65904 15871718 ~ 15876860 (+)
LOC120557571 ikzf4 coding upstream 82993 15851997 ~ 15859771 (+)
LOC120556934 LOC104941416,LOC101064200 coding upstream 108830 15824383 ~ 15833934 (+)
tatdn2 NA coding downstream 2897 15948449 ~ 15960280 (+)
LOC120558102 LOC104943766 coding downstream 46182 15991734 ~ 16011506 (+)
prkcda prkcd,LOC104933455 coding downstream 71427 16016979 ~ 16034962 (+)
rft1 rft1 coding downstream 90422 16035974 ~ 16039274 (+)
mustn1a mustn1 coding downstream 94261 16039813 ~ 16041213 (+)
LOC120557201 NA non-coding upstream 21142 15919385 ~ 15921622 (+)
G38948 NA non-coding upstream 27863 15914539 ~ 15914901 (+)
G38885 LOC104942130 non-coding upstream 180449 15760792 ~ 15762315 (+)
G38852 NA non-coding upstream 187705 15673979 ~ 15755059 (+)
G38860 NA non-coding upstream 213364 15727979 ~ 15729400 (+)
G38966 NA non-coding downstream 39072 15984624 ~ 15985096 (+)
G39052 LOC101067125,LOC103386161,LOC103365890 non-coding downstream 249827 16195379 ~ 16195784 (+)
G39076 LOC104930492,LOC103358728,LOC102300171,LOC101465142 non-coding downstream 289462 16235014 ~ 16251725 (+)
G39113 NA non-coding downstream 557886 16503438 ~ 16510185 (+)
G39134 NA non-coding downstream 607132 16552684 ~ 16556205 (+)
crbn crbn,LOC102793823 other upstream 5667 15923321 ~ 15937097 (+)
G38834 NA other upstream 294913 15645511 ~ 15647851 (+)
calcoco1b LOC104959845,LOC103376572 other upstream 1068305 14865059 ~ 14874459 (+)
znf740a LOC107385642,LOC101469799,LOC102214350,LOC102304359,LOC103376569,LOC107082105,LOC100709046 other upstream 1085695 14765297 ~ 14857069 (+)
G38517 NA other upstream 1126328 14808352 ~ 14816436 (+)
ccdc174 ccdc174 other downstream 19850 15965402 ~ 15974237 (+)
eefsec eefsec,LOC102787825 other downstream 104126 16049678 ~ 16060330 (+)
LOC120557902 rab7,rab7a,LOC102230535,LOC106583206,LOC105017191,LOC101061812 other downstream 203573 16149125 ~ 16158362 (+)
G39104 LOC103385912,LOC104930488,LOC103358732,LOC101079922 other downstream 487686 16433238 ~ 16435229 (+)
G39116 NA other downstream 571984 16517536 ~ 16543580 (+)

Expression


Co-expression Network