mthfr (mthfr)


Basic Information

Item Value
gene id mthfr
gene name mthfr
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053116.1
NCBI id CM020913.1
chromosome length 44101041
location 37297505 ~ 37329403 (-)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039800328.1
AGATGGGTTGTGTGGTTGTGTCAGCTTGACAGACTGCGATCAGTTCTTATTATACATCTGAATAGTCCCACCCTCCATGGTCCCACCCTTTTACACATATGGTGCCACCTTTTTATCATACATGCATGTGTCCCACGCGCTGCAGCAGTTAAAATTCTGTCCATATTTTGCCCTGGATGGGAGACAGTCGGGGAGACCTTTAGGACAACACGCCGGGAAAGcATACGATAATCTGCCGTCATGGTGAACCAGGTTCAGCGCGTGGACGGTAGTTGGCAGTCGTGCAAGAGCGACTCCAGCGGCgccagcaacaacaacagcggcGGCGAGAGCTCCAAGGAGAGCTCGCGGTGTTCCACGCCGGTGCTGGACGTGGACCGGTCCGACCGGCTGCGGGACAAGATGCGGAGAAGGATGGAGTCCGGGGACCGCTGGTTCTCGCTGGAGTTCTTTCCCCCGCGCACCGCCAGCGGAGCTGTGAACCTCATCTCAAGATTTGACCGTATGGGCACCGGAGGGCCCCTGTTTATCGACATCACCTGGCACCCAGCGGGGGACCCGGGCTCGGACAAGGAAACCTCGTCTCTGATGATCGCCAGCACAGCGGTGAATTACTGCGGCCTGGAGAGCATCCTCCACCTGACCTGCTGCAACCAGACCAAAGAGAAGATCAGCGGCCACCTGGCCAAAGCAAAGCACCTGGGCCTCAAAAACATCATGGCACTGAGGGGAGACCCAGTGGGAGCCGactgggaggaagaggagggaggctTCAACTACGCCACCGACCTCGTTAAACACATCCGGTCAGAGTTTGATGACTACTTTGACATCTGCGTTGCCGGCTACCCTACAGGCCACCCCGAGGCAGAGAGCTACGAGGAGGATCTCCGACACCTGAAGGAGAAGGTGGACGCTGGAGCCGACTTCATCATCACCCAGTTGTTCTTCAGGGCGGACACGTTCCTCAAGTTCCTGGACGACTGCAGGGCGATTGGTATCACGTGTCCCATCCTACCGGGAATCTTCCCCATTCAGGGTTACCAGTCTCTGCGTCAGCTCGTCAAGCTGTCGAAGCTCGAGGTACCGGAGGAGATCACCAGAGTCATCGAGCCCATCAAAGACAACGACGCCGCCATCCGTAACTACGGCATCAAACAGGCGGTGGAGATGTGCCGCGTGCTGCTGGACAGCGGCAAGGTACCGGGGCTCCACTTCTACACCCTGAACCGAGAGGTGGCCACCATGGAGGTGCTCCGCCAGCTGGGTCTGTGGATAGAGGACCCCAGGCGGCCTCTTCCCTGGGCAGTGAGCGCCCATCCCAAACGGAAGGTAGAAGACGTTCGACCCATCTTCTGGGCGTCTCGGCCCAAGAGCTACATCTACAGAACCCAGGACTGGGACGAGTTCCCCAACGGCCGATGGGGAAACTCCTCGTCTCCAGCGTTCGGCGAGCTGAACGACTACTACCTGTTCTACCTGAAGAGCAAGTCGTCTAAAGACGCTCTGCTGAAGATGTGGGGCGATGAGCTGATGAGTGAAGAGAGCGTCTACGAGGTCTTCACCTGCTACATCACAGCCCAGCCAAACCGCAGCGGACACAAGGTGATGTGTTTGCCGTGGAACGATGAGCCTTTGGCCCCGGAGACCAACCTGCTGAAGGACGAGCTGGAGAAGGTGAACCGACGAGGAGTCCTCACCATCAACTCCCAGCCCAACATCAACGGAAAACCCTCCACAGATCCCATAGCCGGCTGGGGGCCTGCAGGAGGCTACGTCTTCCAAAAGGCCTATCTGGAGTTCTTCACCTCCAGTGAAAATGTGAACGCTCTCCTCAAAGTACTGAAGAAGTACGAGCCCCGCGTCAACTACCACATTGTTAACGTGCACGGCCGTAACCTGACCAACGCCCCGGACATGCAGCCTAACGCTGTGACGTGGGGGATCTTTCCTGGCAGGGAGATCGTTCAGCCGACCGTGGTGGACCCTGACAGCTTCATGTATTGGAAGGACGAGGCCTTCGCCCTGTGGATCGAGCAGTGGGCGAAGCTCTACGAAGACGAGTCTCCTTCACGGATGATCATCAAGTACATCCACGACAACTACTTCCTGGTCAACCTGGTGGACAACGACTTCCCTCTGGAGAGCTGTCTGTGGCAGGTCATCGACGATATGTTCGAGCTGCTCGACGCGGCTCCGGAGACGCTCCACGATGCTCCGGAGACGCTCCACGCCGCTCCGGAGACGCTCGACGCCGCTCCGGAGACGCTCGACGCCGCTCCAGAGACGCTCCACGCCGCTCCGGAGACGCTCCACGATGCTCCGGAGACGCTCCACGCCGCTCCGGAGACGCTCCACGATGCTCCGGAGACGCTCCACGCCGCTCCGGAGACGCTCCACGATGCTCCGGAGACGCTCCACGATGCTCCGGAGACGCTCCACGCAGCCGCAGCTCCAGAGCCGGTGAAAGACGGCGCAGCCTccaaataaaaatttttttaggGACAGAAAGAAACACTACAGAATGGTCGATATTTTATGCATTgccaaaaaaaatgaaaaaatgctgcTACTTACAAAACCGATCGTAGCAAATATTAAGGATTGTACTtcacagtatttttttaaaaaggtttttatgaatgttttttaacatttaagtgAATGGAAAATGAAAACGTACTGTCTCACCGGAACTAAATAGGaaacattaaatattttttacctCCATGATCAGTAGCTTCATCCTTTTGTagcacttttatttttattttttaaagattcctCGAGGACAAATCTCactgaaaaacaacaattaaGAAAAACGACTCGTAAAgtgaaatgtgaaaatgaaatataCTTTAAAGGCTAGGTTCATATTTggcatcttttttatttttttacaagaaaaagttgactagggCGCTTTTGTAGTAAAAAAGGAAGAAACTGGCAGCGGATTTATTCCAAAAAGCAGCTGAGAGCGTCTTTTGTAGCTATTacaacagctactgctacagtatcctagagcgctatgtggagcggtgctaacgttagattaaaCAAAgaggtggagcgagctagagaaataatagagagagagaaagagagatgtgCTAATGTTAGATAAACAAAGAGGTGGAGCGACCTAGAGAAATAACCGAGAGAGCGAGAggtgctaatgctaacgttagattaaacaaagtggtggagcaagCTAGAG
>XM_039800329.1
GGTGTGCTAGCAGGCCGTTGcATACGATAATCTGCCGTCATGGTGAACCAGGTTCAGCGCGTGGACGGTAGTTGGCAGTCGTGCAAGAGCGACTCCAGCGGCgccagcaacaacaacagcggcGGCGAGAGCTCCAAGGAGAGCTCGCGGTGTTCCACGCCGGTGCTGGACGTGGACCGGTCCGACCGGCTGCGGGACAAGATGCGGAGAAGGATGGAGTCCGGGGACCGCTGGTTCTCGCTGGAGTTCTTTCCCCCGCGCACCGCCAGCGGAGCTGTGAACCTCATCTCAAGATTTGACCGTATGGGCACCGGAGGGCCCCTGTTTATCGACATCACCTGGCACCCAGCGGGGGACCCGGGCTCGGACAAGGAAACCTCGTCTCTGATGATCGCCAGCACAGCGGTGAATTACTGCGGCCTGGAGAGCATCCTCCACCTGACCTGCTGCAACCAGACCAAAGAGAAGATCAGCGGCCACCTGGCCAAAGCAAAGCACCTGGGCCTCAAAAACATCATGGCACTGAGGGGAGACCCAGTGGGAGCCGactgggaggaagaggagggaggctTCAACTACGCCACCGACCTCGTTAAACACATCCGGTCAGAGTTTGATGACTACTTTGACATCTGCGTTGCCGGCTACCCTACAGGCCACCCCGAGGCAGAGAGCTACGAGGAGGATCTCCGACACCTGAAGGAGAAGGTGGACGCTGGAGCCGACTTCATCATCACCCAGTTGTTCTTCAGGGCGGACACGTTCCTCAAGTTCCTGGACGACTGCAGGGCGATTGGTATCACGTGTCCCATCCTACCGGGAATCTTCCCCATTCAGGGTTACCAGTCTCTGCGTCAGCTCGTCAAGCTGTCGAAGCTCGAGGTACCGGAGGAGATCACCAGAGTCATCGAGCCCATCAAAGACAACGACGCCGCCATCCGTAACTACGGCATCAAACAGGCGGTGGAGATGTGCCGCGTGCTGCTGGACAGCGGCAAGGTACCGGGGCTCCACTTCTACACCCTGAACCGAGAGGTGGCCACCATGGAGGTGCTCCGCCAGCTGGGTCTGTGGATAGAGGACCCCAGGCGGCCTCTTCCCTGGGCAGTGAGCGCCCATCCCAAACGGAAGGTAGAAGACGTTCGACCCATCTTCTGGGCGTCTCGGCCCAAGAGCTACATCTACAGAACCCAGGACTGGGACGAGTTCCCCAACGGCCGATGGGGAAACTCCTCGTCTCCAGCGTTCGGCGAGCTGAACGACTACTACCTGTTCTACCTGAAGAGCAAGTCGTCTAAAGACGCTCTGCTGAAGATGTGGGGCGATGAGCTGATGAGTGAAGAGAGCGTCTACGAGGTCTTCACCTGCTACATCACAGCCCAGCCAAACCGCAGCGGACACAAGGTGATGTGTTTGCCGTGGAACGATGAGCCTTTGGCCCCGGAGACCAACCTGCTGAAGGACGAGCTGGAGAAGGTGAACCGACGAGGAGTCCTCACCATCAACTCCCAGCCCAACATCAACGGAAAACCCTCCACAGATCCCATAGCCGGCTGGGGGCCTGCAGGAGGCTACGTCTTCCAAAAGGCCTATCTGGAGTTCTTCACCTCCAGTGAAAATGTGAACGCTCTCCTCAAAGTACTGAAGAAGTACGAGCCCCGCGTCAACTACCACATTGTTAACGTGCACGGCCGTAACCTGACCAACGCCCCGGACATGCAGCCTAACGCTGTGACGTGGGGGATCTTTCCTGGCAGGGAGATCGTTCAGCCGACCGTGGTGGACCCTGACAGCTTCATGTATTGGAAGGACGAGGCCTTCGCCCTGTGGATCGAGCAGTGGGCGAAGCTCTACGAAGACGAGTCTCCTTCACGGATGATCATCAAGTACATCCACGACAACTACTTCCTGGTCAACCTGGTGGACAACGACTTCCCTCTGGAGAGCTGTCTGTGGCAGGTCATCGACGATATGTTCGAGCTGCTCGACGCGGCTCCGGAGACGCTCCACGATGCTCCGGAGACGCTCCACGCCGCTCCGGAGACGCTCGACGCCGCTCCGGAGACGCTCGACGCCGCTCCAGAGACGCTCCACGCCGCTCCGGAGACGCTCCACGATGCTCCGGAGACGCTCCACGCCGCTCCGGAGACGCTCCACGATGCTCCGGAGACGCTCCACGCCGCTCCGGAGACGCTCCACGATGCTCCGGAGACGCTCCACGATGCTCCGGAGACGCTCCACGCAGCCGCAGCTCCAGAGCCGGTGAAAGACGGCGCAGCCTccaaataaaaatttttttaggGACAGAAAGAAACACTACAGAATGGTCGATATTTTATGCATTgccaaaaaaaatgaaaaaatgctgcTACTTACAAAACCGATCGTAGCAAATATTAAGGATTGTACTtcacagtatttttttaaaaaggtttttatgaatgttttttaacatttaagtgAATGGAAAATGAAAACGTACTGTCTCACCGGAACTAAATAGGaaacattaaatattttttacctCCATGATCAGTAGCTTCATCCTTTTGTagcacttttatttttattttttaaagattcctCGAGGACAAATCTCactgaaaaacaacaattaaGAAAAACGACTCGTAAAgtgaaatgtgaaaatgaaatataCTTTAAAGGCTAGGTTCATATTTggcatcttttttatttttttacaagaaaaagttgactagggCGCTTTTGTAGTAAAAAAGGAAGAAACTGGCAGCGGATTTATTCCAAAAAGCAGCTGAGAGCGTCTTTTGTAGCTATTacaacagctactgctacagtatcctagagcgctatgtggagcggtgctaacgttagattaaaCAAAgaggtggagcgagctagagaaataatagagagagagaaagagagatgtgCTAATGTTAGATAAACAAAGAGGTGGAGCGACCTAGAGAAATAACCGAGAGAGCGAGAggtgctaatgctaacgttagattaaacaaagtggtggagcaagCTAGAG

Function

symbol description
mthfr Predicted to enable FAD binding activity and methylenetetrahydrofolate reductase (NAD(P)H) activity. Predicted to be involved in methionine biosynthetic process and tetrahydrofolate interconversion. Predicted to act upstream of or within methionine metabolic process. Predicted to be active in cytosol. Is expressed in anterior neural tube; optic cup; and somite. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); cardiovascular system disease (multiple); hematologic cancer (multiple); and kidney failure (multiple). Orthologous to human MTHFR (methylenetetrahydrofolate reductase).

NR:

description
PREDICTED: methylenetetrahydrofolate reductase

GO: NA

KEGG:

id description
K25004 MTHFR; methylenetetrahydrofolate reductase (NADPH)

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039800328.1 True 3223 mRNA 0.54 12 37297505 37329403
XM_039800329.1 False 3022 mRNA 0.54 12 37297505 37328918

Neighbor

gene id symbol gene type direction distance location
LOC120559612 LOC103363412,LOC108249421,LOC107391357 coding downstream 43464 37220534 ~ 37254041 (-)
tbc1d25 tbc1d25 coding downstream 125301 37156368 ~ 37172204 (-)
LOC120559725 rpl22,LOC102779685,LOC106566811,LOC106572248,LOC100699599,LOC101484027,LOC102785448,LOC103376530,LOC102235575,LOC104936395 coding downstream 235810 37053787 ~ 37061695 (-)
plod1a NA coding downstream 345226 36903077 ~ 36952279 (-)
gmeb2 gmeb2,LOC102776727 coding downstream 431203 36850850 ~ 36866302 (-)
LOC120559054 NA coding upstream 745014 38074417 ~ 38077028 (-)
LOC120559055 NA coding upstream 750478 38079881 ~ 38082216 (-)
tfe3a NA coding upstream 754419 38083822 ~ 38118628 (-)
fgd1 fgd1,LOC103367265 coding upstream 803819 38133222 ~ 38188792 (-)
LOC120559803 LOC102788279,LOC102300940,LOC107099231,LOC104961425 coding upstream 863857 38193260 ~ 38206091 (-)
G56316 NA non-coding downstream 2653 37294547 ~ 37294852 (-)
G56315 NA non-coding downstream 6999 37290148 ~ 37290506 (-)
G56314 NA non-coding downstream 9546 37287650 ~ 37287959 (-)
G56308 NA non-coding downstream 20780 37272393 ~ 37276725 (-)
G56305 NA non-coding downstream 36112 37239917 ~ 37261393 (-)
G56328 NA non-coding upstream 21736 37351139 ~ 37351573 (-)
G56330 NA non-coding upstream 29023 37358426 ~ 37408370 (-)
G56345 NA non-coding upstream 68529 37397932 ~ 37398341 (-)
G56348 NA non-coding upstream 81520 37410923 ~ 37509453 (-)
LOC120559592 NA non-coding upstream 135957 37465360 ~ 37472856 (-)
phc2a LOC103367632,LOC102778931,LOC100708466,LOC102197996 other downstream 296354 36984885 ~ 37001151 (-)
rhoaa LOC106529366,LOC107558917,LOC102777028,LOC107687289,LOC103367639,LOC107599000,LOC103384870,LOC106572042 other downstream 401965 36884803 ~ 36895540 (-)
LOC120559655 mtch1,LOC102799640 other downstream 553373 36723238 ~ 36744132 (-)
G56160 NA other downstream 573296 36681899 ~ 36724209 (-)
LOC120559361 NA other downstream 737546 36557530 ~ 36559959 (-)
G56335 NA other upstream 43232 37372635 ~ 37373316 (-)
G56376 NA other upstream 239657 37569060 ~ 37839849 (-)
LOC120559227 esd other upstream 552765 37882168 ~ 37900343 (-)
G56436 NA other upstream 596791 37926194 ~ 37940548 (-)
LOC120559229 NA other upstream 670599 38000002 ~ 38046669 (-)

Expression


Co-expression Network