chek2 (chek2,LOC102215705)



Basic Information


Item Value
gene id chek2
gene name chek2,LOC102215705
gene type misc
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information


Item Value
chromosome id NC_053117.1
NCBI id CM020914.1
chromosome length 43979800
location 43002255 ~ 43025050 (-)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence


>TU92737
gtgtgtgtgtgtgtgtctctgtgtgtgtgtgtctctgtgtgtgtgtgtgtgtgtgtttgtgtgtctctgtgtgtgtgtgtgtgtgtctctgtgtgtgtgtgtgtgtgtgtctctgtgtgtgtgtgtgtgtgtgtgtgtgtgtgttctctgtgtgtgtgtgtgtgtgtgtctctgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtcttgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtctctgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgttttctcagaGGAGTGTGTGGGGAGTTAAACTGGCCTTAGAGATGTCGTGCAGGAAGTTTGCCGTGAAAATAATTAATAAGAAGAACTTTCAGTCTGAAGGGACCGCGACGAGAAACGCGCAAACTGAGATTCAAATTCTGCAGAGAGTCGACCACCCATGTCTGATTAAAACAGAGGATTTCTATCAGACGGAGGACAGTTACTACATTGTGTTGGAGCTgatggagggaggagagttGTTTCACCGAGTTAAATCTCAGCAGCAGCTCGATGAGTCTGTCGCCAAACTGTATTTTTATCAGATGCTGAGAGCGGTCAAGtacCTCCACAGTGAAGGGATCATCCACAGAGATCTGAAACCGGAGAACATCCTGCTGTCCTCGCAGGACAACGAGTGTCTCATCAAGgtgacAGACTTCAACCAGTCCCGGATCCTGGACGAGTCCCTGCTGATGAGGAGTCTGTGTGGGACGCCGTCCTACCTCGCTCCTGAAGTCTTCACGTCCACGTCGGGATACGGGCTGGCCGTGGACGCGTGGAGCCTCGGAGTCCTGCTCTTCGTCTGtctgGGTGGTTATCCTCCGTTCCATGAAAACTTCAGCCGCCAGTCGATCACGGAGCAGATCATC
>TU92743
tgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtctctgtgtatgtctgttgtgtgtgtgtgtctcccagaAGGATGTGGTCAGGAAGCTGCTGGTAGTTGACCCCAGTAAGAGGATGACTATAGATGAAGCTCTGCAGCATCCCTGGCTCCAGGATGATGTCATGATGAAGACGGCTCACAGACTCATGTTCCCCCCCGacgctgatgctgctgctgccgccgctgccatgcagGAAGTGGAGTCAGCCTCCGGGAGGAAACGAGGACGCggtgaaggagaagaagaagaggaaccTCCAGCCAAACGCagccaagccccgccccctgcCCCGGAGTAGACCAATCACACTCAGCCACGTGTTCACTACTGAAACGCTGTAAATAAAGTTTACATTGATTGCTAATAAAGCCTTTTATGTTTTCCACTCCGTTTGCATCGGCTTTATTTTCTCCAAAGTTTCATAATATTTCTGTTTTGAGACGTCAACAAACTGAAAACCCTTAAAAATCATCGCCATGAcaacttaaaggagaactctgggcaatttttacgttaatcttgatcgctataaatatgcgagTACTGTCCAAtagcaaaaacaacaaacagaatcagtcttagcaaactggagttgctgcagctaatgcccagagctcccagttagctaac
>XM_039802527.1
GCACGGCTCAGCCCGCTTCGTCCTGGCGGTGTATATGAAGCAGCTCGGCGGGTAGGGAGCGGATTTGGAGCCCGGCTGCTGGGCGGGGTTAGTGACCCAGAACGGTACTGAGCCGGTTCTGGTCCCAGATCAGTTTTCATCTGCATCTCCGATACCGTCagtttgaaataaaaacatctCAGCCATCGACGGGCTCCATTAAAAAAACAGCTAATTTAACGTCGCCTTGTTCGCATGATAATATAGACGCTGTTGGATGTGACTGAAGAGAGATGAGGCCCCTCTTTAAAAACTTGAATGTTATTTCATGTTGACATTACGCCGAATTAAGGAGAAGACTATTAGATATTTGGAGGAATTTCCGCTCTTGTTGTCTACGTTCGTATTAGCTGGAAGATGTCTGAAGAGATTCCACATGAGGGGGAGCAGCCCCAGACCACTCAGTCTACCCAGTCCACCCTGTCCCAGGCCCAGTCTACCCAGTCCACCCTGTCCCAGCCCCAGTCTACCCAGTCTCCGTCCCAGGCCCAGTCTACCCAGTCTCCGTCCCAGGCCCAGTCTACCCAGTCTCCGTCCCAGGCCCAGTCTACCCAGTCTGCGTCCCAGGCCCAGTCCACCCAGCCTAAGTCCCAGACTGGTTCCAGTTCTTCCAGCGGGCCGAGGTCTTCCAGCGGCTCGGGGACCCTGAGCAGCGTGGACACCATTCCCGTGACGCTGGCGTCCGTCCCCGAGGAGCCCGAGCCTCAGCCGTGGGGCCGCCTGCTGCCGATGGCCCAGGGCTTCAGGAGCCTCGACTGTCTAGAGGACCAGTATCTGTTCGGCCGGGGGTCCAAGTGTAACTACGTTCTGGACGATCCCGATGAAAAAGGATCCAAAAAGTTCAGAATCTACAGCAAGAAACACTTCAGGATCTACAGAgaGGGCAGTGAGGTGTTCGTGGAGGACTCCAGTAACACGGGACCCTGTGGGCAGTGCTGGTGAGTAGAAGACAGGAAGCTTCCTCTGACCAACAACGCTGTGCTGGCTGGCTGAGCAACCAACAGAGtctttgTGTTCATCGACCTGATGTCAGCTGATGAGTCCAGCTTACCCAGAGAGCTTCAGGAGAAATCGTTCGGACTTACTATCCGGCACaGGAGTGTGTGGGGAGTTAAACTGGCCTTAGAGATGTCGTGCAGGAAGTTTGCCGTGAAAATAATTAATAAGAAGAACTTTCAGTCTGAAGGGACCGCGACGAGAAACGCGCAAACTGAGATTCAAATTCTGCAGAGAGTCGACCACCCATGTCTGATTAAAACAGAGGATTTCTATCAGACGGAGGACAGTTACTACATTGTGTTGGAGCTgatggagggaggagagttGTTTCACCGAGTTAAATCTCAGCAGCAGCTCGATGAGTCTGTCGCCAAACTGTATTTTTATCAGATGCTGAGAGCGGTCAAGtacCTCCACAGTGAAGGGATCATCCACAGAGATCTGAAACCGGAGAACATCCTGCTGTCCTCGCAGGACAACGAGTGTCTCATCAAGgtgACAGACTTCAACCAGTCCCGGATCCTGGGCGAGTCCCTGCTGATGAGGAGTCTGTGTGGGACGCCCTCCTACCCTCCTGAAGTCTTCACGTCCACGTCGGGATACGGGCTGGCCGTGGACGCGTGGAGCCTCGGAGTCCTGCTCTTCGTCTGtctgGGTGGTTATCCTCCGTTCCATGAAAACTTCAGCCGCCAGTCGATCACGGAGCAGATCATCCGCGGAGAGTTCACCATGGTGCCGTCCAAATGGAAACACATCTCTGACCCAGCTaAGGATGTGGTCAGGAAGCTGCTGGTAGTTGACCCCAGTAAGAGGATGACTATAGATGAAGCTCTGCAGCATCCCTGGCTCCAGGATGATGTCATGATGAAGACGGCTCACAGACTCATGTTCCCCCCCGacgctgatgctgctgctgccgccgctgccatgcagGAAGTGGAGTCAGCCTCCGGGAGGAAACGAGGACGCggtgaaggagaagaagaagaggaaccTCCAGCCAAACGCagccaagccccgccccctgcCCCGGAGTAGACCAATCACACTCAGCCACGTGTTCACTACTGAAACGCTGTAAATAAAGTTTACATTGATTGCTAATAAAGCCTTTTATGTTTTCCACTC

Function


symbol description
chek2 Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within cellular response to DNA damage stimulus. Predicted to be active in cytoplasm and nucleus. Is expressed in eye; head; optic tectum; and proliferative region. Human ortholog(s) of this gene implicated in several diseases, including Li-Fraumeni syndrome 2; breast cancer (multiple); colorectal cancer; osteosarcoma; and prostate cancer. Orthologous to human CHEK2 (checkpoint kinase 2).

NR:

description
unnamed protein product

GO:

id name namespace
GO:0006974 cellular response to DNA damage stimulus biological_process
GO:0006468 protein phosphorylation biological_process
GO:0005524 ATP binding molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function

KEGG:

id description
K06641 CHEK2; serine/threonine-protein kinase CHEK2

RNA


RNA id representative length rna type GC content exon number start site end site
TU92737 False 931 TUCP 0.51 7 43004586 43018251
TU92743 False 703 TUCP 0.48 3 43002255 43003347
XM_039802527.1 True 2166 mRNA 0.54 17 43002497 43025050

Neighbor


gene id symbol gene type direction distance location
LOC120560194 NA coding downstream 43982 42873897 ~ 42958273 (-)
LOC120561115 NA coding downstream 147913 42822405 ~ 42854342 (-)
LOC120560237 NA coding downstream 179610 42819874 ~ 42822645 (-)
LOC120560234 plpp7,LOC107097912,LOC106531399,LOC103368069,LOC105917130,LOC101484670,LOC108248082 coding downstream 340236 42658356 ~ 42662019 (-)
LOC120560191 NA coding downstream 731044 42262425 ~ 42271211 (-)
snapc4 NA coding upstream 80292 43105342 ~ 43141553 (-)
LOC120561120 NA coding upstream 276569 43301619 ~ 43304446 (-)
LOC120561121 NA coding upstream 283298 43308348 ~ 43310847 (-)
LOC120560199 LOC108248098,LOC101175325,LOC102290088,LOC101464010,LOC103156294,LOC103460382,LOC102193617 coding upstream 455911 43480961 ~ 43528118 (-)
fibcd1a fibcd1,LOC102791113,LOC101470696 coding upstream 532667 43557717 ~ 43582312 (-)
LOC120560258 NA non-coding downstream 30630 42970466 ~ 42971625 (-)
G69184 NA non-coding downstream 182921 42780818 ~ 42819334 (-)
LOC120560255 NA non-coding downstream 230822 42768403 ~ 42771433 (-)
G69189 NA non-coding downstream 298263 42696173 ~ 42703992 (-)
G69175 NA non-coding downstream 346333 42653635 ~ 42655922 (-)
G69258 NA non-coding upstream 12497 43037547 ~ 43038477 (-)
G69266 NA non-coding upstream 64591 43089641 ~ 43091900 (-)
G69246 NA non-coding upstream 78910 43103960 ~ 43104752 (-)
G69271 NA non-coding upstream 126812 43151862 ~ 43153110 (-)
G69251 NA non-coding upstream 141071 43166121 ~ 43194392 (-)
LOC120561114 NA other downstream 192633 42663363 ~ 42809622 (-)
G69140 NA other downstream 465297 42497565 ~ 42536958 (-)
G69105 NA other downstream 869674 42130611 ~ 42132581 (-)
G68921 NA other downstream 885994 42107630 ~ 42116261 (-)
card9 card9,LOC108245830 other upstream 51180 43076230 ~ 43099165 (-)
pomt1 pomt1,LOC103397945,LOC102782456,LOC103398975 other upstream 118338 43143388 ~ 43178989 (-)
G69249 NA other upstream 185969 43211019 ~ 43218894 (-)
LOC120561119 LOC102192266,LOC107386210,LOC101154874,LOC101486486 other upstream 198427 43223477 ~ 43251312 (-)
G69356 LOC106941104,LOC103460379 other upstream 346717 43371767 ~ 43380599 (-)

Expression



Co-expression Network