isl1a (isl1,LOC103469637,LOC107374027,LOC107661270,LOC103141950,LOC102231175)
Chromosome Information
Item |
Value |
chromosome id |
NC_053117.1 |
NCBI id |
CM020914.1
|
chromosome length |
43979800 |
location |
4103017 ~ 4109223 (-) |
genome version |
GENO_Pfluv_1.0_2020_eurasian_perch_Genome |
Sequence
>XM_039802069.1
CCGCTTGTCAGGATCAGAGCGCCACACATACCGGcaacacacactatacacacacactccctctccGAGCCGGACAGCACAGCCCCTGGCCCGGCAAGCCCCGGCAGCGGAGGACACATCCAGGCTTCCAGGCGCCGCAGCCCGCCGTGACAGTGGACCTAACATCGCCTTACTTTGTGGACATGGGAGACATGGGGGACCCGCCGAAAAAGAAGCGGCTGGTGTCTCTGTGCGTGGGCTGCGGGAACCAGATCCACGACCAGTACATCCTGCGGGTCTCCCCGGACCTGGAGTGGCACGCCGCCTGTCTCAAATGTGCCGAGTGCAGCCAGTACCTGGACGAGTCGTGCACGTGTTTCGTCAGGGACGGAAAGACGTACTGTAAACGGGACTACATCAGGTTGTACGGGATCAAATGCGCGAAATGCAACATTGGCTTCAGCAAGAACGACTTCGTGATGCGGGCCCGCTCCAAGGTCTACCACATCGAGTGTTTCCGCTGCGTGGCCTGCAGCCGGCAGCTCATCCCGGGGGACGAGTTCGCTCTGCGGGAGGACGGGCTCTTCTGCCGGGCCGACCACGACGTGGTGGAGCGGGCCAGCCTGGGCGCTGGAGACCCGCTCAGCCCGCTGCACCCCGCCAGACCGCTGCAGATGGCAGCAGAACCAATCTCGGCCCGGCAGCCCGCGCTTCGGCCTCACGTGCACAAACAGCCGGAGAAGACCACCCGGGTCCGGACGGTGCTGAACGAGAAGCAGCTGCACACGCTGCGGACTTGCTATAACGCCAACCCGAGGCCTGACGCCCTCATGAAGGAGCAGCTGGTGGAGATGACCGGCCTCAGCCCGCGGGTCATCCGGGTCTGGTTCCAGAACAAGCGGTGCAAGGACAAGAAGAGGAGCATCCTGAtgaagcagctgcagcagcaacagcccAACGACAAGACGAACATCCAGGGAATGACTGGCACCCCGATGGTGGCGGCCAGTCCGGAGCGGCACGACGGCGGCCTCCAGGCCAACCCGGTGGAGGTGCAGAGCTACCAGCCGCCCTGGAAGGTCCTCAGCGACTTCGCCCTGCAGAGCGACATCGACCAGCCGGCCTTCCAACAACTGGTCAGTTTCTCGGAGGGCGGTCCGGGATCGAACTCGACGGGCAGCGAGGTAGCGTCCATGTCGTCCCAGCTTCCAGACACGCCGAACAGCATGGTGTCCAGCCCCATCGAGGCCTgagccgccgccgccgccgccgccgacGCCGCATCCtccccatccatccatcccgaccgaccgaccgacggacggacggacggaccgCACCAAACAACCCCCCTGGTTGTATTATGACACTGTGAAGACAATCATGGGATTTTACCACAGCCACACATTCTAATGTCCatccagagagagacacacggaCGGACGGATGCGTCATCATGGCCCGGTGCTGCACGTTCGAGCGCCTGGTTACAGTTGCCAAAACGAGAGACACGAACCGGACTGCATCGATAC
>XM_039802070.1
CGCTTGTCAGGATCAGAGCGCCACACATACCGGcaacacacactatacacacacactccctctccGAGCCGGACAGCACAGCCCCTGGCCCGGCAAGCCCCGGCAGCGGAGGACACATCCAGGCTTCCAGGCGCCGCAGCCCGCCGTGACAGTGGACCTAACATCGCCTTACTTTGTGGACATGGGAGACATGGGGGACCCGCCGAAAAAGAAGCGGCTGGTGTCTCTGTGCGTGGGCTGCGGGAACCAGATCCACGACCAGTACATCCTGCGGGTCTCCCCGGACCTGGAGTGGCACGCCGCCTGTCTCAAATGTGCCGAGTGCAGCCAGTACCTGGACGAGTCGTGCACGTGTTTCGTCAGGGACGGAAAGACGTACTGTAAACGGGACTACATCAGGTTGTACGGGATCAAATGCGCGAAATGCAACATTGGCTTCAGCAAGAACGACTTCGTGATGCGGGCCCGCTCCAAGGTCTACCACATCGAGTGTTTCCGCTGCGTGGCCTGCAGCCGGCAGCTCATCCCGGGGGACGAGTTCGCTCTGCGGGAGGACGGGCTCTTCTGCCGGGCCGACCACGACGTGGTGGAGCGGGCCAGCCTGGGCGCTGGAGACCCGCTCAGCCCGCTGCACCCCGCCAGACCGCTGCAGATGGCAGAACCAATCTCGGCCCGGCAGCCCGCGCTTCGGCCTCACGTGCACAAACAGCCGGAGAAGACCACCCGGGTCCGGACGGTGCTGAACGAGAAGCAGCTGCACACGCTGCGGACTTGCTATAACGCCAACCCGAGGCCTGACGCCCTCATGAAGGAGCAGCTGGTGGAGATGACCGGCCTCAGCCCGCGGGTCATCCGGGTCTGGTTCCAGAACAAGCGGTGCAAGGACAAGAAGAGGAGCATCCTGAtgaagcagctgcagcagcaacagcccAACGACAAGACGAACATCCAGGGAATGACTGGCACCCCGATGGTGGCGGCCAGTCCGGAGCGGCACGACGGCGGCCTCCAGGCCAACCCGGTGGAGGTGCAGAGCTACCAGCCGCCCTGGAAGGTCCTCAGCGACTTCGCCCTGCAGAGCGACATCGACCAGCCGGCCTTCCAACAACTGGTCAGTTTCTCGGAGGGCGGTCCGGGATCGAACTCGACGGGCAGCGAGGTAGCGTCCATGTCGTCCCAGCTTCCAGACACGCCGAACAGCATGGTGTCCAGCCCCATCGAGGCCTgagccgccgccgccgccgccgccgacGCCGCATCCtccccatccatccatcccgaccgaccgaccgacggacggacggacggaccgCACCAAACAACCCCCCTGGTTGTATTATGACACTGTGAAGACAATCATGGGATTTTACCACAGCCACACATTCTAATGTCCatccagagagagacacacggaCGGACGGATGCGTCATCATGGCCCGGTGCTGCACGTTCGAGCGCCTGGTTACAGTTGCCAAAACGAGAGACACGAACCGGACTGCATCGATAC
Function
symbol |
description |
isl1
|
Enables DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor binding activity; and cis-regulatory region sequence-specific DNA binding activity. Involved in cardiac cell fate determination; positive regulation of transcription by RNA polymerase II; and secondary heart field specification. Predicted to be part of chromatin. Predicted to be active in nucleus. Implicated in type 1 diabetes mellitus and type 2 diabetes mellitus.
|
NR:
description |
PREDICTED: insulin gene enhancer protein ISL-1 |
GO:
id |
name |
namespace |
GO:0021522
|
spinal cord motor neuron differentiation |
biological_process |
GO:0006355
|
regulation of transcription, DNA-templated |
biological_process |
GO:0055011
|
atrial cardiac muscle cell differentiation |
biological_process |
GO:0055012
|
ventricular cardiac muscle cell differentiation |
biological_process |
GO:0031017
|
exocrine pancreas development |
biological_process |
GO:0008016
|
regulation of heart contraction |
biological_process |
GO:0048665
|
neuron fate specification |
biological_process |
GO:0048936
|
peripheral nervous system neuron axonogenesis |
biological_process |
GO:0005634
|
nucleus |
cellular_component |
GO:0043565
|
sequence-specific DNA binding |
molecular_function |
GO:0003700
|
DNA-binding transcription factor activity |
molecular_function |
GO:0008270
|
zinc ion binding |
molecular_function |
KEGG:
id |
description |
K09370
|
ISL1; insulin gene enhancer protein ISL-1 |
RNA
RNA id |
representative |
length |
rna type |
GC content |
exon number |
start site |
end site |
XM_039802069.1 |
True |
1511 |
mRNA |
0.63 |
6 |
4103017 |
4109223 |
XM_039802070.1 |
False |
1507 |
mRNA |
0.63 |
6 |
4103017 |
4109222 |
Neighbor
gene id |
symbol |
gene type |
direction |
distance |
location |
ak6 |
ak6
|
coding |
downstream |
254507 |
3844642 ~ 3848510 (-) |
ydjc |
ydjc
|
coding |
downstream |
258977 |
3830346 ~ 3844040 (-) |
pias2 |
pias2
|
coding |
downstream |
286197 |
3799032 ~ 3816820 (-) |
ptar1 |
ptar1
|
coding |
downstream |
481537 |
3606395 ~ 3621480 (-) |
apba1a |
apba1
|
coding |
downstream |
499859 |
3555073 ~ 3603158 (-) |
LOC120560167 |
NA
|
coding |
upstream |
352206 |
4461429 ~ 4471480 (-) |
pnpla7b |
pnpla7
|
coding |
upstream |
368052 |
4477275 ~ 4529746 (-) |
dph7 |
dph7
|
coding |
upstream |
422745 |
4531968 ~ 4543886 (-) |
LOC120559971 |
NA
|
coding |
upstream |
529881 |
4639104 ~ 4642738 (-) |
si:ch211-158d24.2 |
megf9,LOC102787576
|
coding |
upstream |
535381 |
4644604 ~ 4695210 (-) |
LOC120560054 |
NA
|
non-coding |
downstream |
103 |
4099798 ~ 4102914 (-) |
LOC120560115 |
NA
|
non-coding |
downstream |
110073 |
3985628 ~ 3992944 (-) |
G59039 |
NA
|
non-coding |
downstream |
206292 |
3895712 ~ 3896725 (-) |
G59029 |
NA
|
non-coding |
downstream |
236929 |
3861844 ~ 3866088 (-) |
G58995 |
LOC104961333,LOC107396654,LOC101067868,LOC102226353,LOC108248341,LOC107088009
|
non-coding |
downstream |
275591 |
3818433 ~ 3827426 (-) |
G59098 |
NA
|
non-coding |
upstream |
74130 |
4183353 ~ 4183917 (-) |
G59101 |
NA
|
non-coding |
upstream |
78038 |
4187261 ~ 4187472 (-) |
G59197 |
NA
|
non-coding |
upstream |
304536 |
4413759 ~ 4413981 (-) |
G59207 |
NA
|
non-coding |
upstream |
345467 |
4454690 ~ 4461071 (-) |
LOC120560046 |
LOC103358197
|
non-coding |
upstream |
439502 |
4548725 ~ 4557613 (-) |
G58994 |
NA
|
other |
downstream |
413679 |
3688629 ~ 3689338 (-) |
G58920 |
LOC106099046,LOC107687292,LOC107712180,LOC107663003
|
other |
downstream |
686163 |
3415627 ~ 3416854 (-) |
G58919 |
NA
|
other |
downstream |
705521 |
3397169 ~ 3397496 (-) |
si:ch211-102c2.4 |
NA
|
other |
downstream |
862954 |
3232606 ~ 3240063 (-) |
tnc |
tnc,LOC104930867,LOC103356464
|
other |
downstream |
968468 |
3049669 ~ 3134549 (-) |
golph3a |
golph3,LOC103397487,LOC108249570
|
other |
upstream |
100525 |
4209748 ~ 4224568 (-) |
sub1b |
sub1
|
other |
upstream |
314926 |
4424149 ~ 4430090 (-) |
LOC120560375 |
NA
|
other |
upstream |
323621 |
4432844 ~ 4436316 (-) |
LOC120561493 |
NA
|
other |
upstream |
1357000 |
5466223 ~ 5466437 (-) |
LOC120561494 |
NA
|
other |
upstream |
1480350 |
5589573 ~ 5591810 (-) |
Expression