mthfd2 (mthfd2,LOC103363193)


Basic Information

Item Value
gene id mthfd2
gene name mthfd2,LOC103363193
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053117.1
NCBI id CM020914.1
chromosome length 43979800
location 19883210 ~ 19887470 (+)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039803582.1
GtctatgcttcctcctccacagcTCCACAGACGTCGCTGACTGTCAGCCTAGGTGGTGTGTTACGTAACCgtgtttctcttctcttctcttttcttctcctctcagCCGGTCACAATGGCAGCGATCAGGGCTCTCAGGAAACTGTGCCAACACTCCCAGCATCAAGTCTGTAAACTGCACACGTCCGCCTCGAGACAGGAGGCGGTGGTCATCTCAGGAAAGAAACTAGCACGACAGATTCGAGAAGAGGTCCGGGCTGATGTGGATAAATGGGTTTTAGCTGGCCACAGGAGACCCCATCTGAGTGTGGTTCTGGTGGGAGAAAACCCAGCCAGCCACTCCTACGTCCTGAATAAGACACGATCTGCAGCTGATGTTGGAATCTCTAGTGAGACCATTGTCAAGCATTCAGACATCAGCGAGGAGGAGTTATTAGACCTGATCTACAAACTTAACACAGACCATCGTGTTGATGGCCTGCTGGTCCAGCTGCCTCTCCCAGATCACATTGATGAGCGGACAATCTGTAATGCAGTTTCCCCTACCAAGGACGTGGACGGTTTCCACGTAGTTAACGTGGGTCGCATGTGCCTGGATCAGTCCACCATGCTCCCTGCCACTCCCTGGGGAGTCATGGAAATTATTAAACGCACAGGTATTCCTACTATTGGGAAGAATGTCGTGGTTGCAGGACGCTCCAAGAATGTGGGCATGCCCATTGCCATGTTACTGCATACAGACGGCCGTCATGAGAGGCCCGGAGGTGATGCCACGGTAACCATTTCTCACCGTTACACCCCAAAGGAGCAACTTTGCCAACACACTAAAATTGCTGATATCATCGTGGCTGCTGCAGGGATTCCGAACCTCATTACCTCCGACATGATCAAAGAGGGAGCAGCGGTGATTGACGTTGGAATAAACAGAGTGCAGGACCCAGTCACAGGAAAGAGCAGACTGGTTGGAGATGTGGATTTTGAAGGCGTGAGACAGAAGGCGGGCTTCATCACCCCTGTGCCCGGAGGTGTGGGACCCATGACAGTGGCAATGCTAATGAAGAACACTGTCAAGGCAGCTAAGAACGTTCTGCTGTTTCCTCCAGAGAGGATCCGCATGGTGGCTACATCCTAATGGGCAGCAGAAAATCCAAGCCAGAGTGACACATTCCACCCCTGTTATTTTTTACTTGGAGCAACCTGAGGACCTTCATTTGCACACGGACTGGAAAGATGATAGCTTTAAGACTTTCTTCCTGCTGGCATCTTTAACCTCTTCTAACTTCAAGTTCAGCCATGTGTAGACTGTTACATTCACTCATGCAGCTGTGTTTTATGTAACAAGGTTTTTAGTATTTATCATTTGCAATgtatttttggggggttttaaGGAATCTTATGGGAggaatattattttatttattactatATTGACATAATATTTAAACATGAATGGAGGCAGGTTACAGCATATAGGCCTgtctgttgtgtttcttttccaTTAGTTTAGCCTTATGTACCAAGAGTGATAAGGGCTAACATCATCAGGAACACCTATATTTATCAATATACAAGCTTTAAAGATTCACAATTGCCtttgtaaaaactttgaaataaatactACAAATATGTTCACACATT

Function

symbol description
mthfd2 Predicted to enable methenyltetrahydrofolate cyclohydrolase activity; methylenetetrahydrofolate dehydrogenase (NAD+) activity; and methylenetetrahydrofolate dehydrogenase (NADP+) activity. Predicted to be involved in tetrahydrofolate interconversion. Predicted to act upstream of or within one-carbon metabolic process. Predicted to be active in mitochondrion. Is expressed in anterior neural tube and optic cup. Orthologous to human MTHFD2 (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase).

NR:

description
bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like

GO:

id name namespace
GO:0009396 folic acid-containing compound biosynthetic process biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity molecular_function

KEGG:

id description
K13403 MTHFD2; methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039803582.1 True 1638 mRNA 0.47 8 19883210 19887470

Neighbor

gene id symbol gene type direction distance location
selenom selenom,LOC100701119,LOC101070319,LOC101478641 coding upstream 76668 19800122 ~ 19806542 (+)
sftpbb sftpb coding upstream 129233 19749201 ~ 19753977 (+)
spaw NA coding upstream 335924 19544329 ~ 19547286 (+)
dguok LOC104941578,LOC108234509,LOC102204634,LOC103375338 coding upstream 338945 19540250 ~ 19544265 (+)
tcn2 NA coding upstream 343176 19536302 ~ 19540034 (+)
arl6ip4 arl6ip4,LOC102787162 coding downstream 1780 19889250 ~ 19891659 (+)
mtrfr clg12h12orf65,LOC102787453,LOC102198566,LOC102302482,LOC104962307 coding downstream 54003 19941473 ~ 19942849 (+)
kmt5ab LOC102787754 coding downstream 56358 19943828 ~ 19948469 (+)
LOC120560983 NA coding downstream 96365 19983835 ~ 19984968 (+)
LOC120560984 NA coding downstream 114480 20001950 ~ 20003895 (+)
G63128 NA non-coding upstream 8066 19873101 ~ 19875144 (+)
G63087 NA non-coding upstream 50883 19780965 ~ 19832327 (+)
G63076 LOC103376870 non-coding upstream 135741 19746949 ~ 19747469 (+)
G63068 LOC103148513,LOC106959092,LOC106925485,LOC102232144 non-coding upstream 165735 19716498 ~ 19717475 (+)
G63029 NA non-coding upstream 226714 19656232 ~ 19656496 (+)
G63189 NA non-coding downstream 127534 20015004 ~ 20015249 (+)
G63190 NA non-coding downstream 128762 20016232 ~ 20016661 (+)
G63192 NA non-coding downstream 130647 20018117 ~ 20018412 (+)
G63202 NA non-coding downstream 137443 20024913 ~ 20025748 (+)
G63203 NA non-coding downstream 138285 20025755 ~ 20026755 (+)
c6h2orf68 c21h2orf68,c9h2orf68,LOC104941594,LOC103363183,LOC104920309 other upstream 119686 19759596 ~ 19763524 (+)
rasl10a rasl10a other upstream 434260 19430401 ~ 19448950 (+)
tmem119a LOC103353570,LOC104946818 other upstream 801556 19076561 ~ 19081654 (+)
mvk mvk,LOC102798305 other upstream 1140811 18737518 ~ 18742399 (+)
acacb acacb other upstream 1197747 18661157 ~ 18685463 (+)
vps13a vps13a other downstream 513477 20400947 ~ 20442093 (+)
wdr31 wdr31,LOC102796061 other downstream 586181 20473651 ~ 20490586 (+)
G63480 rbm19 other downstream 788947 20676417 ~ 20677916 (+)
LOC120560787 NA other downstream 1701406 21588876 ~ 21599289 (+)
G63905 NA other downstream 3042429 22929899 ~ 22930205 (+)

Expression


Co-expression Network