XLOC_005181 (cyp26a1)



Basic Information


Item Value
gene id XLOC_005181
gene name cyp26a1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007123.7
NCBI id CM002896.2
chromosome length 49182954
location 8954761 ~ 8958353 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00009997
TTTGTGCGTAAAGACGCGTCTCCTCTCCAGAAGCTTGTTTTTCGTTTTGGCGATCAGTTGCGCGCTTCAACATGGGGCTGTACACCCTTATGGTCACCTTTCTCTGCACCATCGTGCTACCCGTTTTACTCTTTCTCGCCGCGGTGAAGTTGTGGGAGATGTTAATGATCCGACGAGTCGATCCGAACTGCAGAAGTCCTCTACCGCCAGGTACCATGGGCTTGCCGTTCATTGGAGAAACGCTCCAGCTGATCCTCCAGAGAAGGAAGTTTCTGCGCATGAAACGGCAGAAATACGGGTGCATCTACAAGACGCACCTCTTCGGGAACCCGACTGTCAGGGTGATGGGAGCTGATAATGTGAGGCAGATTCTGCTGGGCGAACACAAGCTGGTGTCTGTTCAGTGGCCAGCATCAGTGAGAACCATCCTGGGCTCTGACACCCTCTCCAATGTCCATGGAGTTCaacacaaaaacaagaaaaagGCCATTATGAGGGCGTTCTCTCGAGATGCTCTGGAGCACTACATTCCCGTGATCCAGCAGGAGGTGAAGAGCGCCATACAGGAATGGCTGCAAAAAGACTCCTGCGTGCTGGTTTATCCAGAAATGAAGAAACTCATGTTTCGGATAGCTATGAGAATCCTGCTTGGTTTTGAACCAGAGCAAATAAAGACGGACGAGCAAGAACTGGTGGAAGCTTTTGAGGAAATGATCAAAAACTTGTTCTCCTTGCCAATCGACGTTCCTTTCAGTGGTCTGTACAGGGGTTTGAGGGCACGCAATTTCATTCACTCTAAAATTGAGGAAAACATCAGGAAGAAAATTCAAGATGACGACAATGAAAACGAGCAGAAATACAAAGACGCTCTTCAGCTGTTGATCGAGAACAGCAGAAGAAGTGACGAACCTTTTAGTTTGCAGGCGATGAAAGAAGCAGCTACAGAGCTTCTATTTGGAGGTCATGAAACCACCGCCAGTACTGCAACCTCACTAGTCATGTTTCTGGGTCTGAACACAGAAGTGGTGCAGAAGGTCAGAGAGGAGGTTCAGGAGAAGGTTGAAATGGGCATGTATACACCGGGAAAAGGCTTGAGCATGGAGCTGTTGGACCAGCTGAAGTACACTGGATGTGTGATTAAAGAAACTCTCAGAATCAACCCTCCTGTTCCTGGAGGATTCAGAGTCGCACTCAAAACCTTTGAATTGAATGGTTACCAAATTCCTAAAGGATGGAACGTCATTTACAGCATCTGTGACACGCACGATGTGGCCGACGTCTTTCCAAACAAAGACGAGTTCCAGCCGGAGAGATTCATGAGCAAAGGTCTGGAGGACGGGTCCAGGTTTAACTACATCCCCTTCGGAGGAGGATCCAGGATGTGTGTGGGCAAAGAGTTCGCCAAAGTGTTACTCAAGATCTTTTTAGTTGAGTTAACGCAGCATTGCAATTGGATTCTCTCAAACGGACCCCCGACAATGAAAACAGGCCCGACTGTTTACCCAGTGGACAATCTCCCTACCAAATTCACTAGTTATGTCAGAAATTAGCCTAACCGGAGCTTTgtacatatgtttttattttagatgaaCTGTGATGTattggatattttctattttgtttatataaagcAGATGTGTATATAAGTCTATGCGAGGAAGCGAAAACGAGGGCACTACTTTCTCATGGATCACTGTAATGCTACAGAGTGTCTgtgatgtatatttataatgtagtTGTGTTATATAGCTTTTGTACTGTATGCAACTTATTTAACTCGCTCTTTATCTCAtgggttttatttaataaaacatgttctTACAAATTTCA
>TCONS_00009998
ACATGCATTTGTGAGCTTTGTGCCAATAACGCATCTCCATCACACACAGAGAAGGAAGTTTCTGCGCATGAAACGGCAGAAATACGGGTGCATCTACAAGACGCACCTCTTCGGGAACCCGACTGTCAGGGTGATGGGAGCTGATAATGTGAGGCAGATTCTGCTGGGCGAACACAAGCTGGTGTCTGTTCAGTGGCCAGCATCAGTGAGAACCATCCTGGGCTCTGACACCCTCTCCAATGTCCATGGAGTTCaacacaaaaacaagaaaaagGCCATTATGAGGGCGTTCTCTCGAGATGCTCTGGAGCACTACATTCCCGTGATCCAGCAGGAGGTGAAGAGCGCCATACAGGAATGGCTGCAAAAAGACTCCTGCGTGCTGGTTTATCCAGAAATGAAGAAACTCATGTTTCGGATAGCTATGAGAATCCTGCTTGGTTTTGAACCAGAGCAAATAAAGACGGACGAGCAAGAACTGGTGGAAGCTTTTGAGGAAATGATCAAAAACTTGTTCTCCTTGCCAATCGACGTTCCTTTCAGTGGTCTGTACAGGGGTTTGAGGGCACGCAATTTCATTCACTCTAAAATTGAGGAAAACATCAGGAAGAAAATTCAAGATGACGACAATGAAAACGAGCAGAAATACAAAGACGCTCTTCAGCTGTTGATCGAGAACAGCAGAAGAAGTGACGAACCTTTTAGTTTGCAGGCGATGAAAGAAGCAGCTACAGAGCTTCTATTTGGAGGTCATGAAACCACCGCCAGTACTGCAACCTCACTAGTCATGTTTCTGGGTCTGAACACAGAAGTGGTGCAGAAGGTCAGAGAGGAG

Function


symbol description
cyp26a1 Enables retinoic acid 4-hydroxylase activity. Acts upstream of or within several processes, including animal organ development; cellular response to vitamin A; and retinoid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Is expressed in several structures, including head; mesoderm; neural plate; pleuroperitoneal region; and presumptive neural plate. Used to study holoprosencephaly. Orthologous to human CYP26A1 (cytochrome P450 family 26 subfamily A member 1).

GO:

id name namespace
GO:0090242 retinoic acid receptor signaling pathway involved in somitogenesis biological_process
GO:0021797 forebrain anterior/posterior pattern specification biological_process
GO:0071299 cellular response to vitamin A biological_process
GO:0007507 heart development biological_process
GO:0001756 somitogenesis biological_process
GO:0003131 mesodermal-endodermal cell signaling biological_process
GO:0016125 sterol metabolic process biological_process
GO:0003151 outflow tract morphogenesis biological_process
GO:0031016 pancreas development biological_process
GO:0055014 atrial cardiac muscle cell development biological_process
GO:0048854 brain morphogenesis biological_process
GO:0021661 rhombomere 4 morphogenesis biological_process
GO:0001568 blood vessel development biological_process
GO:0042573 retinoic acid metabolic process biological_process
GO:0042574 retinal metabolic process biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0034653 retinoic acid catabolic process biological_process
GO:0030902 hindbrain development biological_process
GO:0001944 vasculature development biological_process
GO:0030917 midbrain-hindbrain boundary development biological_process
GO:0034672 anterior/posterior pattern specification involved in pronephros development biological_process
GO:0005783 endoplasmic reticulum cellular_component
GO:0005789 endoplasmic reticulum membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0043231 intracellular membrane-bounded organelle cellular_component
GO:0008401 retinoic acid 4-hydroxylase activity molecular_function
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen molecular_function
GO:0004497 monooxygenase activity molecular_function
GO:0005506 iron ion binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0016491 oxidoreductase activity molecular_function
GO:0020037 heme binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-990415-44 Enables retinoic acid 4-hydroxylase activity. Acts upstream of or within several processes, including animal organ development; cellular response to vitamin A; and retinoid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Is expressed in several structures, including head; mesoderm; neural plate; pleuroperitoneal region; and presumptive neural plate. Used to study holoprosencephaly. Orthologous to human CYP26A1 (cytochrome P450 family 26 subfamily A member 1).

Ensembl:

ensembl_id ENSDARG00000033999

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00009997 False 1830 mRNA 0.45 7 8954761 8958353
TCONS_00009998 True 835 mRNA 0.47 4 8956399 8958011

Neighbor


gene id symbol gene type direction distance location
XLOC_005180 CR354554.1 coding downstream 94454 8860193 ~ 8860307 (-)
XLOC_005179 jmjd1cb coding downstream 136762 8581875 ~ 8817999 (-)
XLOC_005178 NA coding downstream 379736 8573933 ~ 8575025 (-)
XLOC_005177 CR932364.1 coding downstream 443576 8509640 ~ 8511185 (-)
XLOC_005176 egr2b coding downstream 450483 8483838 ~ 8504278 (-)
XLOC_005182 exoc6 coding upstream 9922 8968275 ~ 9087566 (-)
XLOC_005183 adam8b coding upstream 138610 9096963 ~ 9132682 (-)
XLOC_005184 CR854953.1 coding upstream 158699 9117052 ~ 9117178 (-)
XLOC_005185 NA coding upstream 269033 9227386 ~ 9237794 (-)
XLOC_005186 pth3r coding upstream 299104 9257457 ~ 9294819 (-)
XLOC_005175 NA non-coding downstream 474053 8477459 ~ 8480708 (-)
XLOC_005174 CR354434.1 non-coding downstream 510740 8443904 ~ 8444021 (-)
XLOC_005173 NA non-coding downstream 560116 8388330 ~ 8394645 (-)
XLOC_005187 CR457459.1 non-coding upstream 387011 9345364 ~ 9345485 (-)
XLOC_005195 AL732629.1 non-coding upstream 689875 9648228 ~ 9648345 (-)
XLOC_005196 AL732629.2 non-coding upstream 711574 9669927 ~ 9671137 (-)

Expression



Co-expression Network