XLOC_005186 (pth3r)


Basic Information

Item Value
gene id XLOC_005186
gene name pth3r
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007123.7
NCBI id CM002896.2
chromosome length 49182954
location 9257457 ~ 9294819 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00010007
TTACACCACTAACCTCACAGGAGATCACATCTCTGGACACATCTCCACAAGTCTCTCTTTAAAACATCTACAATTGGACTGACAAATCTCTTCTTTAATCAAGGATCTgagttaatacaaaaaaaaatctgatgaatGGAAGAAAATCATCTGTGATGGTATTCCAGAAGTTAAAAtctcaacaaaaacaaacaacggGTCGGACTTCAACAGATGTGTGTCCGCTTGACACGGCAGCATCAGAAAGAAACAACATCTTTAACACAATGAAGAAGTAATGGCTGCAAACGTCTGCGCTTCTCTCCACATCGACGCGACTGCCATGTCCTGAAGAGAAACAGGAGCTCTCTGGAGAGCAGGAGTTCTGGAAAAGGTCAAAGGTCTTGGGTTAAGCATGGTGTCAGTGGAGGTCTCTGTGGCTTTAGTGCTGTGCTGTGTTTTGATGGGAGCCAGAGCTCTGATTGATTCAGATGATGTCATCACAAGAGATGAACAGATCTTTCTCCTCATTGGTGCGCGGTCGAGGTGTGAGAGAACCATCCGTGCACAGTCAGACGTGGTCAGAGAGAATAACTGCGCTCCTGAGTGGGATGGGATCATTTGCTGGCCCACAGGAAAACCCAATCAGATGGTGGCAGTTCTGTGTCCTGAGTACATCTATGACTTCAACCACAGAGgaTACGCGTATCGACACTGTGATGCATCAGGTAACTGGGAGCAGGTGTCCATTATAAACCGGACGTGGGCAAACTACACGGAATGCACCACTTACCTGCACACCAACCACAGTGATCAGGAGgaagtGTTTGAGCGCCTTTACCTCATGTACACTATTGGATACTCCATATCACTGGCAGCGTTACTGGTGGCGGTCTCTATCCTTTGCTATTTCAAACGTCTCCACTGCACTCGTAACTACATCCACATCCACCTCTTCACCTCGTTCATATGTCGAGCAATCAGTATTTTTGTGAAAGACGCCGTTCTTTACGCCGTCACGAATGATGGAGAACTAGAAGATGGGGCAGTGGAACAAAGACCCATGGTGGGCTGCAAGGCTGCTGTGACCCTCTTCCTGTATCTGTTGGCGACCAATCATTATTGGATCCTGGTGGAGGGTTTGTACTTGCATAGTCTGATCTTCATGGCCTTCCTGTCTGATAAGAACTGCCTGTGGGCTTTAACAATCATAGGCTGGGGGATCCCAGCAGTGTTTGTGTCTATATGGGTCAGTGCCAGGGTGTCTCTGGCAGACACACAGTGCTGGGATATCAGCGCAGGCAATCTAAAATGGATCTATCAAGTACCAATCCTGGCAGCCATTGTTGTAAACTTCTTCCTCTTCCTCAATATCATCAGGGTTTTGGCCTCTAAGTTGTGGGAAACAAACACGGGAAAACTGGACCCTAGACAGCAGTACAGGAAGCTGCTGAAGTCAACAATGGTGCTGATGCCACTGTTTGGAGTTCATTACATGCTGTTCATGGCTCTTCCGTACACTGATGTGACTGGTTTGCTGTGGCAGATTCAGATGCATTACGAGATGCTCTTCAATTCTTCACAGGGTTTCTTTGTGGCGTTTATTTACTGCTTCTGCAATGGGGAGGTGCAGGCAGAGGTGAAGAAGGCCTGGTTGCGACGCAGTCTTGCGTTAGACCTGAAGCAGAAGGCTCGAGTCCACAGCAGTGCGGGATGTGGAAGTGGTTACTATGGAGGAATGATGTCCCACACCACCACACAGAGCGTGTGTCTCAGTGTCAGTGGTGCTAAAGGCGGTCATTCTCTGCACACCATAGGAGCCAAAGGACAATCCCGTCTACAACATTCAGGAAACTTACCCGGCTACGCGCCTCAGGACACAGAGACTTTGTTTTACCCAGTGGTCCCAAAGCAGAAAGAGACTCCATGCAGACAGAGCAGCAGGAATGCAGAGGAAAGCGAGCATGATTTTGAGCCATATTTCGTAGCGGATGAGGAACATTCTGGATCCATGTCTTGGAAAGAACTAGAAACGATGCTTTGATGTAACTTGCTGGATATTATAAGTGGTGCTTGCTATTGTCAGAAGTTCTAagttataaaagcttgttttttttgCCACAGAATACaaaacattacaataataattgtaGCTTTTTATCTC

Function

symbol description
pth3r Enables parathyroid hormone receptor activity and peptide hormone binding activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and cell surface receptor signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in bone tissue; gill; liver; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Eiken syndrome; Jansen's metaphyseal chondrodysplasia; chondrodysplasia Blomstrand type; osteochondrodysplasia; and primary failure of tooth eruption. Orthologous to human PTH1R (parathyroid hormone 1 receptor).

GO:

id name namespace
GO:0007186 G protein-coupled receptor signaling pathway biological_process
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway biological_process
GO:0007165 signal transduction biological_process
GO:0007166 cell surface receptor signaling pathway biological_process
GO:0005886 plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0017046 peptide hormone binding molecular_function
GO:0008528 G protein-coupled peptide receptor activity molecular_function
GO:0004888 transmembrane signaling receptor activity molecular_function
GO:0004930 G protein-coupled receptor activity molecular_function
GO:0004991 parathyroid hormone receptor activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-991123-12 Enables parathyroid hormone receptor activity and peptide hormone binding activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and cell surface receptor signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in bone tissue; gill; liver; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Eiken syndrome; Jansen's metaphyseal chondrodysplasia; chondrodysplasia Blomstrand type; osteochondrodysplasia; and primary failure of tooth eruption. Orthologous to human PTH1R (parathyroid hormone 1 receptor).

Ensembl:

ensembl_id ENSDARG00000018418

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00010007 True 2143 mRNA 0.47 14 9257457 9294819

Neighbor

gene id symbol gene type direction distance location
XLOC_005185 NA coding downstream 19663 9227386 ~ 9237794 (-)
XLOC_005183 adam8b coding downstream 124775 9096963 ~ 9132682 (-)
XLOC_005184 CR854953.1 coding downstream 140279 9117052 ~ 9117178 (-)
XLOC_005182 exoc6 coding downstream 169891 8968275 ~ 9087566 (-)
XLOC_005181 cyp26a1 coding downstream 299104 8954761 ~ 8958353 (-)
XLOC_005187 CR457459.1 coding upstream 50545 9345364 ~ 9345485 (-)
XLOC_005188 erbb2 coding upstream 65497 9360316 ~ 9438227 (-)
XLOC_005189 pgap3 coding upstream 154846 9449665 ~ 9468618 (-)
XLOC_005190 si:ch211-207i20.2 coding upstream 188056 9482875 ~ 9498060 (-)
XLOC_005191 si:ch211-207i20.3 coding upstream 215658 9510477 ~ 9516981 (-)
XLOC_005180 CR354554.1 non-coding downstream 397150 8860193 ~ 8860307 (-)
XLOC_005178 NA non-coding downstream 682432 8573933 ~ 8575025 (-)
XLOC_005175 NA non-coding downstream 776749 8477459 ~ 8480708 (-)
XLOC_005195 AL732629.1 non-coding upstream 353409 9648228 ~ 9648345 (-)
XLOC_005196 AL732629.2 non-coding upstream 375108 9669927 ~ 9671137 (-)
XLOC_005199 BX928755.1 non-coding upstream 765817 10060636 ~ 10063668 (-)
XLOC_005200 NA non-coding upstream 829841 10124660 ~ 10129902 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000047_00248944_00266154 PTH1RB coding CI01000047 null 248944 ~ 266207 (+)