XLOC_005209 (rac1a)



Basic Information


Item Value
gene id XLOC_005209
gene name rac1a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007123.7
NCBI id CM002896.2
chromosome length 49182954
location 10464897 ~ 10476448 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00010041
GCAGCTCTTCTCCAGTCCATCAGGAGGCAGCAGAGAGTCTGTTTATTGTTCGGGACGGGACgggatatatatgtgtgtgcgtgcggaCCGGGATCTGAGATTTTTTGGGTGGTGGCTGTTTGTTTAACTGGAAGCAGCGGCAGTAAATGCGCCGGAATGCAGGATTCCAGCTAACTTTTCTCCGTCGAGTTTGAGCGAAATTCCTCATTTTCTGTCGACTTCTATCGACTCCGCTCTTGTTTTGCGTGTTGAATTGTGAGGGCGGGTGTCTCTGGCACAGCAgcttttattgattcattcacaGATACAGCTAGCGGGATAGCGTGCTAAACGAACACAGATGCAGGCCATAAAGTGTGTGGTCGTCGGGGACGGggCTGTGGGAAAAACATGCCTTCTGATCAGCTACACCACCAATGCTTTTCCTGGGGAATACATTCCCACTGTgtTTGATAATTATTCTGCAAATGTGATGGTCGATGGGAAACCAGTAAACCTGGGATTGTGGGATACAGCAGGACAAGAGGATTATGACAGGCTTCGACCGCTTTCCTACCCTCAGACGGATGTGTTCCTGATCTGCTTCTCTCTTGTGAGTCCGGCCTCATTTGAAAACGTCCGTGCAAAGTGGTATCCGGAGGTCAGACATCATTGCCCTAACACTCCAATAATTCTTGTTGGGACTAAGCTTGATTTGCGAGATGACAAGGACACCATCGAAAAGTTAAAGGAGAAGAAACTCACTCCCATCACCTACCCTCAAGGCCTTGCTATGGCCAAAGAAATAGGAGCTGTGAAGTACCTGGAGTGCTCTGCCTTAACCCAACGCGGCCTTAAAACTGTGTTCGATGAAGCCATCCGTGCAGTGCTGTGTCCACCTCCggtgaagaggaggaggagaagatgtCTCCTTCTGTGAACTGACTGCGCCCACAGCACCAGCTGCAATCTGAGCTCACCTGAGAGAAGAACAATGGAAGCGGGGATGACGGGAAATGATATGGTGTATTCATACAGatatttctctttctctctctcttgaaTTGTAATTATAATTACGCCACTAACTAGCTGTTAAGATGCCAGAGTATTTACTTTGAGAGATGAAGAGCGGCATCCATAGTCATTTCCCAATGTACACTAAGAAATTCCTGCTGCCTTCTAATGACCTTCTTTCTTTTCCCTTCATTTTGATGTTAGGAAACTACATACTCCTTTTCTCTTTCTCCATCTTTGTGAGTCCACGTGTTTTGTTTACAATCTGCGTTTTTGTAGAGAATGAAATATTGCCAAAAGTTAAACCTGCATCTCAGTTTGCTCACACTAACGCTCTCGTTTTCCTTGAGCACTTGGGAAGGGGGGCGGTTGTCAGAGGCAGATTGCAGTAATACTGAAGGAACTATTTTACAAGAGGAAAGTtgaagaaacacttttttttcccccGATGCTAGagactttatttttctttaagtgTATAAGAAACAAACCTAGTTAAATGCATATAACAGCTTTGTTTTGTCAAGAGTATAGCATATTTTCACTACTGTATCTGAATTTAAGAAGACATGTCATGTTTAAACTCTCTGTGTTTTAGTCTGTCTATTGGATGAGTCTGGCAGTGTTTTATCCACTTTTACAGTCCCAGTGTTGTATTTAGACTACAGAAACATCTCTACTGTATACTTGATAACAGTAATTGTTAGGGTCATCAAGTATTAAATCTCTAATTGATCTTCACACATGATCCGGTGGTTGTGATTAGCCACATGGAGTGTTCAATTTTGACAGTTCAGTAATGACGATTGAAATGCttcatttattcatgcttttacTGTCTCCACTAAATCTACAGTGTATTAACCTTTGTgtctaaaatacaaaaatgtaaaaaca
>TCONS_00010042
TTTGTCATTGTCATTCAGGCACAAACCTCTCTGTGTTTCTGTGGCTCTGTTTCACTCAGGGAAACAAGTGGAGTCAATTTACAGTTCATTAATGCAGCAGGCTAACCAGTGCTTTGTTTTTACTGAATAGTTTAATAATTCTTAAGAAAAGCTGAACAAAAGGAGAGATTTGTCTGATTGTGTTTTTCATTTGTGTAGGATGTGTTCCTGATCTGCTTCTCTCTTGTGAGTCCGGCCTCATTTGAAAACGTCCGTGCAAAGTGGTATCCGGAGGTCAGACATCATTGCCCTAACACTCCAATAATTCTTGTTGGGACTAAGCTTGATTTGCGAGATGACAAGGACACCATCGAAAAGTTAAAGGAGAAGAAACTCACTCCCATCACCTACCCTCAAGGCCTTGCTATGGCCAAAGAAATAGGAGCTGTGAAGTACCTGGAGTGCTCTGCCTTAACCCAACGCGGCCTTAAAACTGTGTTCGATGAAGCCATCCGTGCAGTGCTGTGTCCACCTCCggtgaagaggaggaggagaagatgtCTCCTTCTGTGAACTGACTGCGCCCACAGCACCAGCTGCAATCTGAGCTCACCTGAGAGAAGAACAATGGAAGCGGGGATGACGGGAAATGATATGGTGTATTCATACAGatatttctctttctctctctcttgaaTTGTAATTATAATTACGCCACTAACTAGCTGTTAAGATGCCAGAGTATTTACTTTGAGAGATGAAGAGCGGCATCCATAGTCATTTCCCAATGTACACTAAGAAATTCCTGCTGCCTTCTAA

Function


symbol description
rac1a Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Acts upstream of or within cell migration involved in gastrulation; myoblast fusion; and neutrophil chemotaxis. Predicted to be active in several cellular components, including cell cortex; cytoplasmic vesicle; and dendritic spine. Is expressed in liver; retina; and retinal ganglion cell layer. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 48; colon adenocarcinoma; and pancreatic adenocarcinoma. Orthologous to human RAC1 (Rac family small GTPase 1).

GO:

id name namespace
GO:0042074 cell migration involved in gastrulation biological_process
GO:0007520 myoblast fusion biological_process
GO:1902622 regulation of neutrophil migration biological_process
GO:0007264 small GTPase mediated signal transduction biological_process
GO:0043652 engulfment of apoptotic cell biological_process
GO:0032956 regulation of actin cytoskeleton organization biological_process
GO:0007015 actin filament organization biological_process
GO:0016601 Rac protein signal transduction biological_process
GO:0030593 neutrophil chemotaxis biological_process
GO:0030865 cortical cytoskeleton organization biological_process
GO:0030031 cell projection assembly biological_process
GO:0030036 actin cytoskeleton organization biological_process
GO:0008045 motor neuron axon guidance biological_process
GO:0008360 regulation of cell shape biological_process
GO:0007163 establishment or maintenance of cell polarity biological_process
GO:0042995 cell projection cellular_component
GO:0005856 cytoskeleton cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005938 cell cortex cellular_component
GO:0031410 cytoplasmic vesicle cellular_component
GO:0043197 dendritic spine cellular_component
GO:0031982 vesicle cellular_component
GO:0043231 intracellular membrane-bounded organelle cellular_component
GO:0005737 cytoplasm cellular_component
GO:0003924 GTPase activity molecular_function
GO:0005525 GTP binding molecular_function
GO:0019901 protein kinase binding molecular_function
GO:0000166 nucleotide binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030131-5415 Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Acts upstream of or within cell migration involved in gastrulation; myoblast fusion; and neutrophil chemotaxis. Predicted to be active in several cellular components, including cell cortex; cytoplasmic vesicle; and dendritic spine. Is expressed in liver; retina; and retinal ganglion cell layer. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 48; colon adenocarcinoma; and pancreatic adenocarcinoma. Orthologous to human RAC1 (Rac family small GTPase 1).

Ensembl:

ensembl_id ENSDARG00000074849

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00010041 False 1893 mRNA 0.43 6 10464897 10476448
TCONS_00010042 True 798 lncRNA 0.44 3 10465625 10470405

Neighbor


gene id symbol gene type direction distance location
XLOC_005208 uqcrc2b coding downstream 23236 10424676 ~ 10441661 (-)
XLOC_005207 mosmob coding downstream 42942 10412009 ~ 10421955 (-)
XLOC_005206 eef2k coding downstream 54927 10381957 ~ 10409970 (-)
XLOC_005205 mki67 coding downstream 83615 10366617 ~ 10381282 (-)
XLOC_005204 ndc80 coding downstream 98928 10353333 ~ 10365969 (-)
XLOC_005210 zgc:152977 coding upstream 2218 10478666 ~ 10512911 (-)
XLOC_005211 myof coding upstream 41025 10517473 ~ 10567188 (-)
XLOC_005212 med24 coding upstream 167626 10644074 ~ 10674606 (-)
XLOC_005213 FO704786.1 coding upstream 202578 10679026 ~ 10705916 (-)
XLOC_005214 NA coding upstream 292683 10769131 ~ 10772946 (-)
XLOC_005200 NA non-coding downstream 334995 10124660 ~ 10129902 (-)
XLOC_005199 BX928755.1 non-coding downstream 401229 10060636 ~ 10063668 (-)
XLOC_005196 AL732629.2 non-coding downstream 793760 9669927 ~ 9671137 (-)
XLOC_005195 AL732629.1 non-coding downstream 816552 9648228 ~ 9648345 (-)
XLOC_005187 CR457459.1 non-coding downstream 1119412 9345364 ~ 9345485 (-)
XLOC_005222 BX572641.1 non-coding upstream 1858768 12335216 ~ 12335331 (-)
XLOC_005224 NA non-coding upstream 2626418 13102866 ~ 13106223 (-)
XLOC_005237 NA non-coding upstream 3661838 14138286 ~ 14144159 (-)
XLOC_005240 NA non-coding upstream 4363339 14839787 ~ 14840559 (-)

Expression



Co-expression Network