XLOC_005218 (htra1b)


Basic Information

Item Value
gene id XLOC_005218
gene name htra1b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007123.7
NCBI id CM002896.2
chromosome length 49182954
location 11388724 ~ 11457625 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00010054
AGCACATCAAACTTGGTCAAGTTCACTGCAGTTTAACCTTTTATTTGTCCCGTGACGTTTTCCAAATCTCATTAACTTGGAAATATTTGACTTGAAAGTTTTCTGCTTCTGATTATAGTCGTAAAATGCGTCTTTTGATTCTGTGCGCGTCTATTATTCTGGTACCGCTGCTGTGCGATGCGCGGATCATTAAGCGTTATGTGATCGGCTGTCCGGAGCGCTGTGATAAGAGTCTTTGTCCGCCTATACCGCCCGACTGTCTGGCCGGTGACATCCTGGACCAGTGCGACTGCTGCCCAGTGTGCGCGGCCGGCGAGGGTGAGTCCTGCGGCGGCACAGGGAAACTGGGAGACCCGGAGTGTGGAGAAGGTCTGGAATGCGCTGTGTCTGACGGGGTTGGTGCAACGACTACCGTGAGACGGAGAGGAAAGACCGGCGTGTGCGTGTGCAAGAGTTCTGAACCGGTCTGCGGCAGTGATGGGGTGTCCTACAGGAACATCTGCGAACTCAAGAGGGTCAGTAACCGGGCGCAGAAGCTTCAGCAGCCACCCATCATCTTCATCCAGAGAGGAGCCTGCGGGAAAGGCCACGAGGAGAATCCAGATAGTCTCCGGCACAGATATAACTTCATCGCTGATGTGGTGGAGAAGATCGCTCCAGCTGTGGTTCACATTGAATTATTCCGCAAAAATGTCTTCAATCGGGAAGTGGCGGTGGCCAGCGGCTCTGGTTTTGTGGTGTCTGAAGATGGTCTGATTGTAACTAATGCTCATGTGGTAGCCAACAAACATCGGGTGAAGGTCGAACTGAAGACAGGGACCACCTATGATGCCAAAATCAAAGACGTAGATGAGAAAGCAGACATCGCTCTCATCAAAATAGACGCCCCGATGAAGCTCCCTGTGCTGTTGTTGGGCCGGTCAGCTGATCTGAGACCAGGTGAATTTGTGGTGGCAATTGGCAGTCCGTTCTCCCTTCAGAACACAGTGACCACAGGCATCGTCAGCACTACCCAGAGAGGTGGCAAAGAGCTGGGCCTGCGCAACTCTGATATGGACTACATCCAGACAGATGCCATCATCAATTATGGTAATTCCGGAGGGCCCCTGGTGAATCTGGATGGGGAAGTGATTGGAATCAACACACTGAAGGTGACCGCAGGAATATCCTTCGCCATTCCCTCTGACAAGATCCGACAGTTCCTGGCTGAGTCTCACGACAGGCAGGCTAAAGGAAAAACAGCCACAAAAAAGAAGTATATTGGTGTGAGGATGATGACGTTAACTCCAACACTTGCTAAGGAGCTAAAGCAGAGAAAAAATGATTTCCCAGATGTCACCTCTGGTGCTTACGTCATTGAAGTTATTCCCAAAACACCAGCTGAAGTTGGCGGTTTGAAGGAGAGTGACGTCATAATCAGCATTAACGGTCAGAGGATCACATCGGCCAGCGACGTCAGCACGGCCATCAAGACAGACGAAAGCCTGAGAGCAGTGGTACGGCGCGGAAATGAAGACATTATCCTCACCATCATTCCTGAAGAGATCGACCCTTGACCACCCTCACGCTCACCTTGAGCTGGTTCTCAGACTTTTACTGAGAGTGTGTCTGGAGTCGCACTCAATCTAGAAATCAATCATAATGAACACttccaaacccaaccatcatcaaaACTTAGAACAGCAAatgtcctttgtttttttttttgccttttctcATATATGAAGCCATTTTCTGCTTATTCATTAGCATACCATCTTAGAATAAGTCTTTTGTAAATAGATATGAGAATTTAGCGCTGTGTTCACACTATacaagcattttttgttattgtttaaaggagcgcttcattttttttaaataactcccctagagttaaacagtttaccatttttaaatccactGAGCTGATCTTTAGGTATGGTAGAAGCACTTTTATTTTAGCTTAGCATGAATCATTGAATTTGATTATAGGCCATTGGCATCTAAATTAAAAAAGATACAAATTGTTCATCTTTAAATAGTCAAGCTTTACATAGGAAGATTATTGACACTCTtgattgaaatattttaattggATGCTAAAGGTCTGGATGCGAttgaatgatttatgctaagctaagctaagctaaaagtgctccctggagattggctgaatggattaactCTAGGGGAATTGTAAaatttccaaaaaagtggagtgtttctttaaaaggcgtctaatagacgtctaaactgTGACATCTTGGCTAATACAAGGCTATGTTTGGACTGTCAGTGAATAGTGAAAATCTAAAAGATGTCTAACAGTAGTTAAAAAATAGacaggaatgaatgaatacagaggtgaagtctgtctaatatgtttatttgatgacttgtTTTAGCCAGGATGCCTGCGTTTATACATCTAGTTGATGTCTTTTAAAAATGCTTGGTGGGCTGACATTcggaaatgtatatatttttttctgttccaAAACCTAGTGAACTGCTTTCGAAGGTTCCATTCGGGATggttgcacaggtttattttaaCTATCAGTAACTGAAACCTAtatctacaaaaaataaataaataaatcagtggaaTTAAACAGGAATGTTTGATTCaacgtgtgtgtttatgtgtgtaatgtacagttgaagtcagaatgattagcccccctgaattattagcccccctgtttatttttctcccattttccccaatttgtttttttctctattctgtttaacagatagcAGATTttctcaatacatttctaaacattattgttttaataactcatctctaataactgatttattttatttttgccatgatgacagtaaaaaatatttaactagatatttttcaagacacttataaagcttaatgtgacatttaaaggcttaactgggttaattaagttacctaggcaagttagggtaattaggcaagttattttataacgattgtttttctgtagactatcataaaaaaataattagcttaaaggggctaataattttgaccttaaaattgttcacAAAAATCAAAAACTCAAAAATCaagtctccagaagaaaaaatattatcagacaaactgtaaaaagttatttgctctattaaacataatttggaaaatatttagaaaagaacacaaattcaaaggggggctaataattctgactttaactgtgtagtTTGCCCAAAAGTTTACTCATATTTACTTACCCTTGGGTGGTTCCAAACCTTAAGGTGTTTCTTTATTCTGTGAAACGCAAAGAAggcattttaaagaaaaataaaaaaaacgtgtACTCTTTGAAATCCATAaataaacactatggaagtcaataatcacgtttccagctttcttcagaatatcttcttttctgttcaacagaaaacattcaaacaggtttggaacaagcaaagggtgagtaaacaacACAATGTTCatggttttttttattaaaattcctCCCAGAATGAATCATGGGAAAACCTGAAGCAAGGACAGCAAAGCATATTTCAGAAGAGCTATTGTTTATACAAAGATACAGACAAAGGCTTGATTCATGCATAAATAGCACAGTATATAAAAACAACTACAAAGAATGCTACAGTAAGCCCAAAAAAGCTGAAGTTTATCCATCCTGAAAGATGACTAAGTGGAATGCCGAAACATGAACAGGCGCGCTCTGAACAATACGGTGTGCACAtgtttgtactgtatgtattttgttCATTTGGAAATATTGCCTTATTAAAGCTAAATAAATTACAA

Function

symbol description
htra1b Predicted to enable insulin-like growth factor binding activity; serine-type endopeptidase activity; and serine-type exopeptidase activity. Predicted to act upstream of or within proteolysis. Predicted to be located in cytosol and extracellular region. Human ortholog(s) of this gene implicated in CADASIL (multiple); hypertension; and macular degeneration (multiple). Orthologous to human HTRA1 (HtrA serine peptidase 1).

GO:

id name namespace
GO:0006508 proteolysis biological_process
GO:0005829 cytosol cellular_component
GO:0005576 extracellular region cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005520 insulin-like growth factor binding molecular_function
GO:0019838 growth factor binding molecular_function
GO:0004252 serine-type endopeptidase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008233 peptidase activity molecular_function
GO:0008236 serine-type peptidase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-080219-7 Predicted to enable insulin-like growth factor binding activity; serine-type endopeptidase activity; and serine-type exopeptidase activity. Predicted to act upstream of or within proteolysis. Predicted to be located in cytosol and extracellular region. Human ortholog(s) of this gene implicated in CADASIL (multiple); hypertension; and macular degeneration (multiple). Orthologous to human HTRA1 (HtrA serine peptidase 1).

Ensembl:

ensembl_id ENSDARG00000014907

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00010054 True 3775 mRNA 0.40 9 11388724 11457625

Neighbor

gene id symbol gene type direction distance location
XLOC_005217 zgc:174164 coding downstream 38825 11315849 ~ 11349899 (-)
XLOC_005216 get4 coding downstream 81958 11262954 ~ 11306766 (-)
XLOC_005215 si:ch73-30l9.1 coding downstream 130320 11244914 ~ 11258404 (-)
XLOC_005214 NA coding downstream 615778 10769131 ~ 10772946 (-)
XLOC_005213 FO704786.1 coding downstream 682808 10679026 ~ 10705916 (-)
XLOC_005219 plekha1b coding upstream 39115 11496740 ~ 11593436 (-)
XLOC_005220 btbd16 coding upstream 143934 11601559 ~ 11649690 (-)
XLOC_005221 atoh1c coding upstream 310489 11768114 ~ 11768889 (-)
XLOC_005222 BX572641.1 coding upstream 877591 12335216 ~ 12335331 (-)
XLOC_005223 ccser2b coding upstream 1497313 12954938 ~ 13081229 (-)
XLOC_005200 NA non-coding downstream 1258822 10124660 ~ 10129902 (-)
XLOC_005199 BX928755.1 non-coding downstream 1325056 10060636 ~ 10063668 (-)
XLOC_005196 AL732629.2 non-coding downstream 1717587 9669927 ~ 9671137 (-)
XLOC_005195 AL732629.1 non-coding downstream 1740379 9648228 ~ 9648345 (-)
XLOC_005224 NA non-coding upstream 1645241 13102866 ~ 13106223 (-)
XLOC_005237 NA non-coding upstream 2680661 14138286 ~ 14144159 (-)
XLOC_005240 NA non-coding upstream 3382162 14839787 ~ 14840559 (-)
XLOC_005243 NA non-coding upstream 3660262 15117887 ~ 15120113 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000161_02552972_02601762 HTRA1B, HTRA1, HTRA1A coding CI01000161 null 2552972 ~ 2601762 (+)
bowfin (Amia calva) AMCG00002818 LOC107660481,LOC107745581,LOC106578991,LOC107598034 coding CM030139.1 CM030139.1 3270489 ~ 3293427 (-)