Gene
RNA
| Item | Value |
|---|---|
| gene id | lrrk2 |
| gene name | lrrk2 |
| gene type | coding |
| species | striped catfish (Pangasianodon hypophthalmus) |
| category of species | economic fish |
| Item | Value |
|---|---|
| chromosome id | NC_047603.1 |
| NCBI id | CM018549.1 |
| chromosome length | 29458963 |
| location | 15577183 ~ 15605737 (+) |
| genome version | GENO_Phyp_1.0_2019_striped_catfish_Genome |
| symbol | description |
|---|---|
| lrrk2 | Predicted to enable several functions, including SNARE binding activity; protein kinase A binding activity; and protein serine/threonine phosphatase activity. Predicted to be involved in several processes, including protein localization to endoplasmic reticulum exit site; regulation of autophagy; and regulation of signal transduction. Predicted to act upstream of or within cell differentiation and phosphorylation. Predicted to be active in several cellular components, including endoplasmic reticulum exit site; mitochondrial outer membrane; and perikaryon. Is expressed in gut; heart; muscle; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Crohn's disease; Parkinson's disease; Parkinson's disease 8; Parkinsonism; and cancer. Orthologous to human LRRK2 (leucine rich repeat kinase 2). |
| description |
|---|
| leucine-rich repeat serine/threonine-protein kinase 2 |
| id | name | namespace |
|---|---|---|
| GO:0007264 | small GTPase mediated signal transduction | biological_process |
| GO:0006468 | protein phosphorylation | biological_process |
| GO:0016310 | phosphorylation | biological_process |
| GO:0005622 | intracellular anatomical structure | cellular_component |
| GO:0005524 | ATP binding | molecular_function |
| GO:0005525 | GTP binding | molecular_function |
| GO:0035639 | purine ribonucleoside triphosphate binding | molecular_function |
| GO:0004672 | protein kinase activity | molecular_function |
| GO:0004674 | protein serine/threonine kinase activity | molecular_function |
| GO:0032550 | purine ribonucleoside binding | molecular_function |
| GO:0032555 | purine ribonucleotide binding | molecular_function |
| id | description |
|---|---|
| K08844 | LRRK2; leucine-rich repeat kinase 2 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| XM_026919060.2 | True | 9028 | mRNA | 0.48 | 51 | 15577183 | 15605737 |
| XM_026919061.2 | False | 9025 | mRNA | 0.48 | 51 | 15577183 | 15605737 |
| XM_026919062.2 | False | 9007 | mRNA | 0.48 | 51 | 15577183 | 15605737 |
| XM_026919063.2 | False | 9004 | mRNA | 0.48 | 51 | 15577183 | 15605737 |
| XM_034307317.1 | False | 8803 | mRNA | 0.48 | 50 | 15577183 | 15605737 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| mphosph6 | mphosph6 | coding | upstream | 128442 | 15446796 ~ 15448741 (+) |
| snx20 | snx20 | coding | upstream | 131128 | 15444108 ~ 15446055 (+) |
| sall1b | LOC108274520 | coding | upstream | 143644 | 15427516 ~ 15433539 (+) |
| rbl2 | rbl2,LOC107659865 | coding | upstream | 155330 | 15406172 ~ 15421853 (+) |
| irx3b | LOC108275042 | coding | upstream | 228619 | 15346438 ~ 15348564 (+) |
| clpxb | clpx,LOC108275190,LOC105913134,LOC108442679 | coding | downstream | 3703 | 15609440 ~ 15620419 (+) |
| si:ch211-87j1.4 | LOC108274534,LOC103040017,LOC108442681,LOC105913127,LOC107701590,LOC107695923,LOC107555711,LOC107723960,LOC107752489,LOC107571669 | coding | downstream | 25318 | 15631055 ~ 15634990 (+) |
| fancf | fancf | coding | downstream | 145402 | 15751139 ~ 15752526 (+) |
| sigirr | sigirr | coding | downstream | 226442 | 15832179 ~ 15841507 (+) |
| hexa | hexa | coding | downstream | 269126 | 15874863 ~ 15882172 (+) |
| G149131 | NA | non-coding | upstream | 7696 | 15567836 ~ 15569487 (+) |
| G149091 | cpne8,LOC108274474 | non-coding | upstream | 93280 | 15483074 ~ 15483903 (+) |
| G149089 | NA | non-coding | upstream | 95155 | 15481687 ~ 15482028 (+) |
| G149088 | NA | non-coding | upstream | 95613 | 15481252 ~ 15481570 (+) |
| G149027 | NA | non-coding | upstream | 125279 | 15451576 ~ 15451904 (+) |
| G149248 | NA | non-coding | downstream | 105276 | 15711013 ~ 15711917 (+) |
| G149268 | NA | non-coding | downstream | 148928 | 15754665 ~ 15754912 (+) |
| G149276 | NA | non-coding | downstream | 166101 | 15771838 ~ 15818368 (+) |
| G149427 | NA | non-coding | downstream | 419107 | 16024844 ~ 16026512 (+) |
| G149428 | NA | non-coding | downstream | 421870 | 16027607 ~ 16028019 (+) |
| fanci | fanci,LOC107673243,LOC107670230,LOC107564606 | other | upstream | 1747852 | 13790973 ~ 13829331 (+) |
| ces2b | LOC108275184 | other | upstream | 1800312 | 13761334 ~ 13776871 (+) |
| prr33 | prr33,LOC108428828,LOC107595228,LOC107742059,LOC107675453 | other | upstream | 2187987 | 13372872 ~ 13389196 (+) |
| zgc:172145 | LOC108275003 | other | upstream | 2223921 | 13349323 ~ 13353262 (+) |
| G147542 | NA | other | upstream | 2659929 | 12916919 ~ 12917254 (+) |
| svip | svip | other | downstream | 115541 | 15721278 ~ 15725091 (+) |
| LOC113529564 | ano9,LOC108442698 | other | downstream | 202253 | 15807990 ~ 15822591 (+) |
| G150589 | LOC108274445 | other | downstream | 2228500 | 17834237 ~ 17842535 (+) |
| tmem17 | tmem17,znf774,LOC107678976 | other | downstream | 2576817 | 18182554 ~ 18184033 (+) |
| rfwd3 | rfwd3,LOC107754982 | other | downstream | 3069273 | 18675010 ~ 18683428 (+) |
