isl2a (isl2,isl2a,LOC107589357,LOC107662481,LOC107712508)


Basic Information

Item Value
gene id isl2a
gene name isl2,isl2a,LOC107589357,LOC107662481,LOC107712508
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047603.1
NCBI id CM018549.1
chromosome length 29458963
location 17130857 ~ 17136035 (+)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026919583.2
TCGGCTACAAGTTCTCGGTGTGCTCGGGCCGCTGCCCACTCCCACTGTGTCCCCTCATCTATAGCAGTGCGCGCTGACCATCCTTTATGCTGGATATTCTACTCCACTCTTCTTTCTTGGGTGATATGGGGGATCATTCAAAAAAGAAGACCGGGATCGCCATGTGTGTGGGCTGCGGAAGTCAGATCCATGACCAGTACATCCTGCGGGTCTCCCCGGACCTGGAGTGGCACGCGGCGTGTCTGAAGTGCGCGGAGTGCAGTCAGTACCTGGACGAGACGTGCACTTGCTTCGTCCGGGACGGCAAGACCTACTGCAAAAGAGACTACGTAAGGTTATTCGGGATTAAATGTGCGAAATGTAACGTGGGCTTCTGCAGCAGTGACCTGGTAATGCGGGCTCGGGACAACGTTTACCACATGGAGTGTTTCAGGTGCTCGGTGTGCAGCAGACACCTCCTGCCGGGAGATGAGTTCTCTCTGCGGGAAGAGGAGCTGCTGTGCCGGGCTGATCACGGGCTGCTGCTGGAGCGCTCCGCGGCGGGCAGCCCACCAATCAGCCCGggaaacacacactccaccagaGCCCTGCACATGGCCGAGCCGGTACCTGTGCGGCAGCCCCCACACCGCAACCACGTCCACAAGCAGTCGGAGAAGACGACCCGGGTGCGCACTGTGCTCAACGAGAAGCAGCTGCACACACTGCGCACATGCTACAACGCCAACCCGCGGCCCGACGCGCTCATGAAGGAGCAGCTGGTGGAGATGACGGGCCTCAGTCCGCGAGTTATCCGCGTCTGGTTCCAGAACAAACGCTGCAAGGACAAGAAGAGGTCCATGCTCATGAAGCaactccagcagcagcagcacagcgACAAAACCAATCTGCAAGGCCTAACAGGGACACCTCTAGTGGCAGGTAGTCCCATCCGGCATGATAACACGGTGCAGGGGAATCCTGTAGAAGTGCAGACGTACCAGCCTCCATGGAAAGCGCTGAGCGAGTTCGCGCTACAGAGTGACCTGGAGCAGCCCGCCTTCCAGCAGCTGGTGTCCTTCTCTGAGTCGGGCTCTCTGGGCACCTCCTCGGGCAGTGATGTGACTTCGCTGTCATCGCAGTTACCCGACACCCCCAACAGCATGGTGTCCAGTCCTGTGGAGACGTGATGGAGTCCAGCGACCTCTGTCCACCCCAGCATGCTGAACCCCACCCCGATCTGCATGAACACAGAGCACCTCACCACCTCCACCTGAGGAACACGACGGAATCACGGAAAACGACATACAGCAACACAGTGGATTTAACTCGGAACGCACAAGTCTGCCAAAACACACGGAGCCAAGCCCCAGGGACTCTCCACACGCGTTTACTCCAGGCGTCAAGACGCGAATCCACAGGGATCCGAGATCTTCCCGAGGAATATGAACAAGTTGACCCACTGTCAACAGCATAACAAATAACAATCATGTCGTTACCAGTATTCATTATGTAGTTTTATCAACACCTGATGACATTTCCCTAATTCAGTGAGACAACAGAGCCACGTTTGTCTTAATGCGCATGATCTCCGAAGACAGTGTATAAAAGTGACATGTAAACTATTTTATCTTTACGGATGGAGGACAAATTGTTTGAACTTCtcgagagaaaaaaagtaagttattgttatttattgtcAGGACAAGAGTCCAAGCGAGAATTAAGAAATGATCTTAATAAACTATGCTAAGTGTTG

Function

symbol description
isl2a Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within blood vessel morphogenesis; exocrine pancreas development; and neuron differentiation. Predicted to be active in nucleus. Is expressed in several structures, including ectoderm; gut; liver and biliary system; nervous system; and neural tube. Orthologous to human ISL2 (ISL LIM homeobox 2).
isl2 Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in axonogenesis; neuron fate specification; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of neuron differentiation and neuron differentiation. Predicted to be part of chromatin. Predicted to be active in nucleus.

NR:

description
insulin gene enhancer protein ISL-2A isoform X2

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0048665 neuron fate specification biological_process
GO:0048675 axon extension biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG:

id description
K18492 ISL2; insulin gene enhancer protein ISL-2

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026919583.2 True 1738 mRNA 0.54 6 17130857 17136035

Neighbor

gene id symbol gene type direction distance location
tmem266 tmem266 coding upstream 17254 17061938 ~ 17113603 (+)
lactb lactb coding upstream 78646 17046001 ~ 17052211 (+)
tpm1 tpm1,LOC106573503,LOC107659515,LOC107739081,LOC107712528,LOC106946143,LOC103141214,LOC107589334 coding upstream 88379 17028077 ~ 17042478 (+)
tln2b tln2,LOC108433629,LOC107659514,LOC107703225,LOC107739102 coding upstream 119007 16895710 ~ 17011850 (+)
foxb1a foxb1,LOC103353681 coding upstream 630749 16498524 ~ 16500108 (+)
atp8b4 atp8b4 coding downstream 126398 17262433 ~ 17283926 (+)
cops2 cops2,LOC107557994,LOC107589327 coding downstream 155352 17291387 ~ 17298220 (+)
cep152 cep152 coding downstream 162706 17298741 ~ 17315242 (+)
zgc:101540 slc27a2,LOC108414297 coding downstream 180638 17316673 ~ 17322858 (+)
duox2 duoxa1 coding downstream 284173 17420208 ~ 17423465 (+)
G149729 NA non-coding upstream 556985 16540599 ~ 16573872 (+)
LOC117597920 NA non-coding upstream 656629 16460380 ~ 16474228 (+)
G149723 NA non-coding upstream 681717 16446039 ~ 16449140 (+)
G149722 NA non-coding upstream 690803 16439706 ~ 16440054 (+)
LOC117597940 NA non-coding upstream 788894 16338590 ~ 16341963 (+)
G150148 NA non-coding downstream 100606 17236641 ~ 17236946 (+)
G150152 sqrdl non-coding downstream 117632 17253667 ~ 17255337 (+)
G150261 LOC108275011 non-coding downstream 294108 17430143 ~ 17434377 (+)
G150265 NA non-coding downstream 310214 17446249 ~ 17446460 (+)
G150268 NA non-coding downstream 320885 17456920 ~ 17457135 (+)
LOC113529564 ano9,LOC108442698 other upstream 1308266 15807990 ~ 15822591 (+)
svip svip other upstream 1405766 15721278 ~ 15725091 (+)
slc5a12 slc5a12 other upstream 1478173 15563306 ~ 15652684 (+)
fanci fanci,LOC107673243,LOC107670230,LOC107564606 other upstream 3301526 13790973 ~ 13829331 (+)
ces2b LOC108275184 other upstream 3353986 13761334 ~ 13776871 (+)
G150589 LOC108274445 other downstream 698202 17834237 ~ 17842535 (+)
tmem17 tmem17,znf774,LOC107678976 other downstream 1046519 18182554 ~ 18184033 (+)
rfwd3 rfwd3,LOC107754982 other downstream 1538975 18675010 ~ 18683428 (+)
urahb LOC108274538 other downstream 1585560 18721595 ~ 18724686 (+)
nfat5a LOC108274760,LOC108428435 other downstream 1611792 18747827 ~ 18796259 (+)

Expression


Co-expression Network