drd4a (drd4,drd4a,LOC107561186,LOC107655149,LOC107726856)


Basic Information

Item Value
gene id drd4a
gene name drd4,drd4a,LOC107561186,LOC107655149,LOC107726856
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047603.1
NCBI id CM018549.1
chromosome length 29458963
location 22184002 ~ 22190803 (+)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026919643.2
cagcactcagcactctGTCAGTCAGAGCTGTGGAACCGAGCAGAGCTGAAAAACACCCCCACACCAGGACCAGAAAGCAGCACCCTGCTGTGTGGGAGCCAATCCTGCATCTCACAGCGGCGGAGAACACAGTATGAGCAACTCTGCTGAGAAGCAGAAAAGTTACTTCTGGAGTTTGGAGTCGTTTTATTTGTTAACGCGCAGATTTGGTGATTGTGTTTGTGCGTAAGGCGCGCGCGTTAATGCGCTTAAAGGAACGTGACGCGCGCCCAGGCTCGAGCGCAGGAGACAGCTCGAAGGGGAAAtcggtctgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgagaaaggcAGAGGTGGTCACAGTGGTTCGGATAATGGCAAAGAGGAGAGTGTTTTTGGACGGAAACTGGTGCAGACGCCTGGCAGATGAGAGGACAGCCTTCAGGCGCAGCTGCCCGCGGTGTGGGGGCTCGTGCTGAAGCGGAGACGCGCGTGGCGCTGAGGAGGAGAGGCACCGGATTTCTACAGAAATGCACACCAACCTCACTGCTTCTGCCAACCACACCGCACAGCTCTCGGCCACGACCCACAACTTTCCCGCACTCATATTTGGGATATTGCTCATCGTCGTGATTATCTGCGGGAACCTGCTCGTGTGCCTCAGCGTGTACAGAGAAAAGGCTTTAAAAACTACAACCAATTACTTTATAGTAAGTTTAGCCGTCGCGGACCTGCTCCTCGCAGTGCTGGTTCTACCCCTGTTTGTGTACGCAGAGTTCCAGGATGGAGTCTGGTCCCTGAACATGACCGTGTGTGATGGCCTGATGACCATGGACGTGATGCTGTGTACTGCCTCCATATTCAACCTTTGCGCAATTAGCATTGACAGGTTTATTGCTGTGTCCATCCCACTGAATTACAACCGCAAACATGTGGACCAGCGGCAGATTGTCCTGCTGTCTGCCACGTGGATCCTGGCACTAGCCGTGGCCTCACCTGTGCTGTTCGGCATCAACGATGTGCCAAATCGGGACCACAGCGAGTGCAAGCTGGAGAACAACAACTATGTGGTCTACTCCTCTGTCTGCTCATTCTTTGTGCCCTGCCCCATCATGCTGCTGCTCTACTGTGGAATATTTCAGGGCCTCAGGAGGTGGGAGGAGGCGAGGAAAGCCAAGCTGAAGAGCAGCACGCAGGCCTGTCAGAAACTTGAGGAGCCACCAGCATCTCTACTGCCACTGGTTTCTCTACCACCACCTCTTCCCCCAGTCATAGAGAATGACTTTACAGACCTTAATCTGAAAGAGACAGACCAGGATCCTGTCCCAGACAGTCCTTATACATTAGACTGTAAGAATGGGCCTGAAGCTTCGCTGACCTTCTCTGATAGTGGTTACAACCAATATCAGAACCAGGAGAAGAAGAGGGCGAAGATTAATGGGAGGGAGAGGAAGGCCATGAGGGTGCTTCCTGTCGTGGTCGGTGCCTTCCTGTTCTGCTGGACTCCGTTCTTCGTGGTGCACACGATGCGTGCTCTGTGTGAGGACTGCGACATTCCCAGCAGTCTCATTAGCATCGTCACATGGTTGGGTTATGTTAACAGTGCCCTCAACCCCATCATCTATACTGTCTTCAACACAGAGTTCAGGAAGTTCTTCAGGAATTTTTTACCTAAATGCTGCTAGACACACTGCATGCCTAATGTTCATTTGGCCAATAAGCTCTGAGCTTGACCATGATTGTAAAATACGGCAATGCTTACATCTCGTCTTTAGTAGAATGTGTATTTTGCGATCACATTGCTGttacattgttttgcatttacacttgaattgaattgctataacagcagaattTCAGTGGGACAGTTGGTTAATTTTAATGGCCTCACTCATAGGTTCTTATTGCATGTTGAACATGACTGACTTTGTTCTTCAGCCTACatctatttcccaaaatgtagtaatttaaatcacagtgaccctgaccaggataaagcatttacttaagatgaatgaatgaacacagtAAATGCAACATGACGTGAGCACTTTGCTTTGTTCAATATGCTCAAACGTTATAAGCCCGTGGCCTTTCATTGTCCCCTGAGCTTCACACATGTCCACTAGCTCCCAcatgcatgagagtaaaaacaacctgctctcatttttttgttggttCCTGTGAGATCTTCTCCTGCCAAATGACTACAGATTTTAGTTTTTACACCACACTGAAATGAATCTGCACTGAAAGAAACATCAGgtttttccacacacactctcaaaatgtatttacttGATGATTATGTATAAGTAAACTTCATCCACCATAGGCCTGTGTGGCTGCAGATTTTCGTTTGAACCAAGTGATTCCTGATTCTCGCATTAAGGAACAGctactttttattctttacaataaacactacatacacttgcaaaggttaaaaaaaattgcctcaATGTTATTATTCTCTCTGTAATTTTCTTAT

Function

symbol description
drd4a Predicted to enable G protein-coupled receptor activity and dopamine neurotransmitter receptor activity, coupled via Gi/Go. Acts upstream of or within spinal cord motor neuron cell fate specification and ventral spinal cord interneuron differentiation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in nervous system. Human ortholog(s) of this gene implicated in several diseases, including Gilles de la Tourette syndrome; antisocial personality disorder; attention deficit hyperactivity disorder; conduct disorder; and dyslexia. Orthologous to human DRD4 (dopamine receptor D4).
drd4 Enables several functions, including SH3 domain binding activity; catecholamine binding activity; and dopamine neurotransmitter receptor activity, coupled via Gi/Go. Involved in several processes, including adenylate cyclase-inhibiting dopamine receptor signaling pathway; arachidonic acid secretion; and regulation of ion transmembrane transporter activity. Located in plasma membrane. Is integral component of plasma membrane. Implicated in several diseases, including Gilles de la Tourette syndrome; antisocial personality disorder; attention deficit hyperactivity disorder; conduct disorder; and dyslexia. Biomarker of Alzheimer's disease; attention deficit hyperactivity disorder; pervasive developmental disorder; and schizophrenia.

NR:

description
PREDICTED: D(4) dopamine receptor-like

GO:

id name namespace
GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway biological_process
GO:0005887 integral component of plasma membrane cellular_component
GO:0004952 dopamine neurotransmitter receptor activity molecular_function

KEGG:

id description
K04147 DRD4; dopamine receptor D4

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026919643.2 True 2493 mRNA 0.48 5 22184002 22190803

Neighbor

gene id symbol gene type direction distance location
ap4e1 ap4e1 coding upstream 27204 22139633 ~ 22156798 (+)
gnb5a gnb5,LOC108432683,LOC106584742,LOC105018176 coding upstream 46910 22129488 ~ 22137092 (+)
myo5c myo5c,LOC106561779 coding upstream 55211 22108347 ~ 22128791 (+)
myo5ab LOC108275443,LOC108432640 coding upstream 76809 22081919 ~ 22107193 (+)
bet1l bet1l,LOC107740886,LOC107559993,LOC107569707 coding upstream 109992 22070646 ~ 22074010 (+)
pidd1 pidd1 coding downstream 92869 22283672 ~ 22296360 (+)
slc25a22a si:dkey-201c1.2,slc25a22,LOC107561181,LOC107732297,LOC107551436,LOC106096417 coding downstream 106224 22297027 ~ 22326565 (+)
ppp1r32 ppp1r32 coding downstream 263397 22454200 ~ 22464122 (+)
LOC113529790 fads2,LOC100305117,LOC108275104 coding downstream 290187 22480990 ~ 22491255 (+)
LOC113529791 LOC108275104 coding downstream 306959 22497762 ~ 22515818 (+)
G152987 NA non-coding upstream 23130 22160658 ~ 22160872 (+)
G152985 NA non-coding upstream 25348 22158432 ~ 22158654 (+)
G152984 LOC100304581 non-coding upstream 25906 22157867 ~ 22158096 (+)
G152838 NA non-coding upstream 372403 21810911 ~ 21811599 (+)
G152736 NA non-coding upstream 559338 21624450 ~ 21624664 (+)
G153013 NA non-coding downstream 24451 22215254 ~ 22215502 (+)
G153026 NA non-coding downstream 39502 22230305 ~ 22231430 (+)
G153063 NA non-coding downstream 113955 22304758 ~ 22306096 (+)
LOC113529793 NA non-coding downstream 358169 22548972 ~ 22550482 (+)
G153439 NA non-coding downstream 581892 22772695 ~ 22772903 (+)
arpp19b arpp19,LOC108275368,LOC107740885,LOC107569706,LOC103909813,LOC107673248,LOC107670207,LOC107559970 other upstream 105506 22076849 ~ 22078496 (+)
LOC113529593 LOC108275426,LOC108432651,LOC103374925,LOC107389115,LOC106531033 other upstream 125844 22052614 ~ 22058158 (+)
LOC113529760 adamts20,LOC107733613,LOC106907901 other upstream 2435922 19661843 ~ 19748080 (+)
srpk2 srpk2,LOC106907745,LOC108428417,LOC103366878,LOC101063511,LOC103134474 other upstream 2799098 19323331 ~ 19384904 (+)
G151401 NA other upstream 2920109 19260624 ~ 19263893 (+)
G153014 zmp:0000001167,LOC108274702,LOC107754369,LOC107551438,LOC107561184,LOC107655150 other downstream 25472 22216275 ~ 22266382 (+)
syt7a syt7,LOC108432693,LOC107655153,LOC107754343,LOC107551433 other downstream 139960 22330763 ~ 22446147 (+)
LOC113529801 LOC108274632,LOC108274583 other downstream 408991 22599794 ~ 22623807 (+)
LOC113529608 NA other downstream 940763 23131566 ~ 23139656 (+)
oaz2a oaz2,LOC108275215,LOC108432726 other downstream 1237035 23427838 ~ 23436830 (+)

Expression


Co-expression Network