anxa2a (anxa2,anxa2a,LOC108433632,LOC107739086,LOC107724175)


Basic Information

Item Value
gene id anxa2a
gene name anxa2,anxa2a,LOC108433632,LOC107739086,LOC107724175
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047603.1
NCBI id CM018549.1
chromosome length 29458963
location 16540852 ~ 16546270 (-)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026919690.2
TCTTGAATACACTTTATGGGTGATTGGCATTTTTTCAACATAAGCACGGTGGTGTTTTTCCTGCTGTGCACTGGAGGAGGAGGCATTACTGCACTGAAGGGAGGGAACAACTCCTGGCAGAGGCTGTGGTATTTAACCACCACACCCTTTTCACTTCTCATAGCTGGAACTCTTCTGTGCATCATCTGCTCACTTAGGACATCTAAGATGGCTTTGGTATCTGAATTCCTGGGTCAGCTGACCCTCAATTTTGGGTCGAGCGATCCCACCTACCCCACTGTGGTTCCTGCAGCTGATTTTGATCCAGACAAAGATGCCACCAGAATAGAGACAGCTATCAAAACTAAAGGTGTGGATGAACAGACCATTATTCAGATCCTCACCAAACGGACATACAGCCAAAGACGAGAAATTGCCTTTGCATATGAGAGGAGAGCCAAGAAGGATATGATTACTGCCCTGAAGGGGGCACTGTCTGGCTCACTCGAGACTGTTATTTTGGGCCTGATGAAGAGCACTGCTCAGTACGATGCCTCTGAGATTAAAGCCTCCATAAAAGGTTTAGGAACAGATGAGGAGACCCTGATTGAGATCCTCTGCTCTCGAAGCAATGCAGAGCTGGTGGAGATTAAGAAAGTCTACAAAGAACtgttCAAAAAGGACCTGGAGAAGGATGTGGCTGGAGACACCTCAGGAGACTTCGCTAAGCTGCTGCTCGCCCTAGTGGCGGCCAAGCGGGATGAGCCAAGCACTGTAGTTGACTATGGGAAAATTGATGAAGATGCCAGAGCACTGTATGAAGCTGGAGTGAAACGGAAGGGCACTGATGTCAAAACCTGGATTAGCATCATGTCAGAGAGGAGTGTCCCTCATCTGCAGAAAGTATTTGACAGATACAAGAGCTACAGTCCCTATGACATGCAGGAGAGCATCAGGAAGGAAGTAAAAGGAGATCTGGAGATGTCCTTCCTTACACTCGTCCAGTGCTTTGAAAACAAACAGCTCTACTTTGCCAGCAGACTCAACGATGCCATGAAGagTAAAGGCGCAAAGGAGAAAGTGGTGACGAGGATCATGATCTCACGCTGTGAGGTTGACCTTAAGAAGATCAGGTCTGAGTTCAAGGCCCAGTTTGGAAAGTCTCTGTACCAGACCCTCTCTGAGCACACTAAAGGAGACTATCAGCAGGCTCTGCTAAGTTTGTGTGGAGGAGATGATTAAAGCAGAGCAGGTAACTGGTTCCAGGACCCTCAGATGCTGTGATCCTCAGGAGCCTTTCGTCTGCTCAGCCCTCGGCTCTCACGTACTGTTCTAGCTTTATGGATAGTCTATAATCTATATGGATCAGTCTATCTCTAACTGGAGTCACAGTGTTTCAAAGAGACCAAAGACAAAAATCCCAATTATGTCATTTGTAGGCTTCTGAAGTAATgactgttgaatgctcaaatctggGGTTGGTAAGCTCAACTGATTGAGTTACATTATCCACAAAGAAGGCAAATGTATTTCTGCATCCCATAAATAAAGGGACAACGCTGTATTAAACTGTGCCATAGTTGACCAttctaatgcttttttttttttttt

Function

symbol description
anxa2a Predicted to enable calcium ion binding activity. Predicted to be located in basement membrane; extracellular region; and membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including EVL; gill; integument; notochord; and periderm. Human ortholog(s) of this gene implicated in osteonecrosis. Orthologous to several human genes including ANXA2 (annexin A2).
anxa2 Enables several functions, including S100 protein binding activity; enzyme inhibitor activity; and phospholipid binding activity. Involved in several processes, including negative regulation of low-density lipoprotein particle receptor catabolic process; positive regulation of cellular component organization; and positive regulation of low-density lipoprotein particle clearance. Located in several cellular components, including bounding membrane of organelle; extracellular exosome; and lipid droplet. Part of AnxA2-p11 complex and PCSK9-AnxA2 complex. Colocalizes with membrane raft. Implicated in osteonecrosis. Biomarker of cholangiocarcinoma; invasive ductal carcinoma; pancreatic ductal carcinoma; and paranasal sinus benign neoplasm.

NR:

description
PREDICTED: annexin A2-A

GO:

id name namespace
GO:0005509 calcium ion binding molecular_function
GO:0005544 calcium-dependent phospholipid binding molecular_function
GO:0004859 phospholipase inhibitor activity molecular_function
GO:0008092 cytoskeletal protein binding molecular_function

KEGG:

id description
K17092 ANXA2; annexin A2

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026919690.2 True 1590 mRNA 0.46 14 16540852 16546270

Neighbor

gene id symbol gene type direction distance location
bnip2 bnip2 coding downstream 82457 16443455 ~ 16458395 (-)
otud7a otud7a,LOC108275340,LOC107715690,LOC107659507,LOC107752330,LOC107698115,LOC107550219,LOC107598848 coding downstream 178477 16325942 ~ 16362375 (-)
trpm1b LOC108274564,LOC108433637,LOC107585966,LOC107750517 coding downstream 272866 16265562 ~ 16267986 (-)
LOC113529693 LOC108274564,LOC108433637,LOC108441836,LOC107750517 coding downstream 277913 16256510 ~ 16262939 (-)
LOC113530180 LOC108274564 coding downstream 286356 16251344 ~ 16254496 (-)
ice2 ice2 coding upstream 1055 16547325 ~ 16566002 (-)
roraa rora,roraa,LOC108433630,LOC106561150,LOC107703215,LOC106573506 coding upstream 21025 16567295 ~ 16800368 (-)
LOC113530224 NA coding upstream 206906 16753176 ~ 16753281 (-)
c2cd4a LOC108275248,LOC108433606 coding upstream 342067 16888337 ~ 16890007 (-)
etfa etfa,LOC107712526,LOC107557988 coding upstream 567484 17113754 ~ 17128284 (-)
G149841 NA non-coding downstream 42391 16496171 ~ 16498461 (-)
G149836 NA non-coding downstream 79807 16460791 ~ 16461045 (-)
G149718 NA non-coding downstream 116248 16422666 ~ 16424604 (-)
G149632 klf13,znf746,LOC108274922,LOC107550220,LOC107598847,LOC107752329 non-coding downstream 222926 16309890 ~ 16317926 (-)
G149649 NA non-coding downstream 285366 16254647 ~ 16255486 (-)
G149854 NA non-coding upstream 66714 16612984 ~ 16614416 (-)
G150089 NA non-coding upstream 472686 17018956 ~ 17019183 (-)
G150036 NA non-coding upstream 481847 17028117 ~ 17052512 (-)
LOC117597939 NA non-coding upstream 528976 17075246 ~ 17078085 (-)
G150130 NA non-coding upstream 579144 17125414 ~ 17150481 (-)
acsbg1 acsbg1 other downstream 312518 16141119 ~ 16228334 (-)
islr2 islr2,LOC107662462 other downstream 548758 15981164 ~ 15992094 (-)
LOC113529470 LOC108275326 other downstream 821277 15711993 ~ 15719575 (-)
LOC113529695 NA other downstream 1311867 15219970 ~ 15228985 (-)
dynlrb2 dynlrb2,LOC103025073,LOC106573385 other downstream 1452792 15086113 ~ 15088060 (-)
LOC113529460 nrg4 other upstream 507083 17053353 ~ 17058906 (-)
fnbp4 fnbp4,LOC107753624,LOC107678983,LOC107573585 other upstream 1658381 18204651 ~ 18214487 (-)
etfbkmt etfbkmt other upstream 1756872 18303142 ~ 18305329 (-)
LOC113530223 NA other upstream 1758368 18304638 ~ 18304801 (-)
parp6b parp6,parp6b,LOC108275327,LOC108436940,LOC107661437,LOC107753615,LOC107598827,LOC107665100 other upstream 1807704 18353974 ~ 18364036 (-)

Expression


Co-expression Network