XLOC_005261 (ctslb)



Basic Information


Item Value
gene id XLOC_005261
gene name ctslb
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007123.7
NCBI id CM002896.2
chromosome length 49182954
location 16617138 ~ 16619757 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00010118
AGCCAATAAGAGACCGCCTCTATGTTCGGACAGGCTATAAAACACACTCAATTGTATGGAATTACAGTCAGTAAGGTTTGCTTGTGAAAGtcCTCCAGGCAGGATGATGTTTGCTTTGCTCGTCACGCTGTACATAAGTGCAGTGTTTGCTGCTCCATCTATAGACATCCAGTTAGATGACCACTGGAACTCCTGGAAGAGCCAGCATGGAAAAAGCTATCATGAGGACGTAGAGGTCGGGAGGAGAATGATTTGGGAGGAGAACTTGAGAAAAATTGAGCAACACAACTTTGAGTATTCCTATGGAAATCACACCTTTAAAATGGGAATGAATCAATTTGGTGACATGACAAATGAGGAGTTCAGACAGGCAATGAATGGTTATACGCATGACCCCAACCAGACGTCACAGGGCCCGTTGTTCATGGAACCGAGCTTTTTTGCAGCCCCACAACAGGTTGACTGGAGACAGAGGGGCTATGTTACTCCTGTCAAAGACCAGAAACAATGTGGATCTTGCTGGTCTTTCAGTTCAACGGGTGCCTTGGAAGGTCAGCTCTTCCGTAAAACTGGAAAGCTGATTTCTATGAGTGAGCAAAACTTGGTGGACTGTTCCAGACCACAGGGCAATCAAGGGTGTAATGGAGGCCTCATGGACCAGGCCTTCCAGTATGTTAAAGAAAACAAGGGGCTGGATTCTGAGCAGTCATACCCTTATCTTGCAAGGGATGATCTGCCATGCCGGTATGACCCCCGTTTTAATGTCGCTAAAATCACCGGATTCGTGGACATTCCCAGCGGTAATGAGCTTGCCCTAATGAATGCTGTTGCTGCTGTGGGTCCTGTATCTGTTGCTATTGACGCATCACATCAATCCCTACAGTTCTATCAGTCTGGCATCTATTATGAGAGAGCATGTAGCAGTAGTCGACTTGATCATGCAGTCTTGGTGGTTGGCTATGGTTATCAGGGTGCTGATGTTGCTGGGAATAGATACTGGATTGTGAAGAACAGCTGGTCTGACAAATGGGGTGACAAAGGCTACATCTACAtggcaaaagacaaaaacaatcaCTGTGGCGTTGCGACAAAGGCCAGCTATCCCCTAATGTAAGGTCACTGGAGCCTTCTCTGCATTCTGAAAAAGACACGTTTATGGTTTctctattttaatgtgtttttatttcttctaTTTTATCAAGTTGTTCTGCTGTTAGGGCTATGATAGTGGTATTTTAGGAAATTCCATTTTTCTTGTGtttcatatattttgtttatcCAAGAAGAAGAATTTTGTACTGGATCTATTTGACCTGCAAAtggataaataataaattttctgGCATGGCAA
>TCONS_00010119
GGATGATGTTTGCTTTGCTCGTCACGCTGTACATAAGTGCAGTGTTTGCTGCTCCATCTATAGACATCCAGTTAGATGACCACTGGAACTCCTGGAAGAGCCAGCATGGAAAAAGCTATCATGAGGACGTAGAGGTCGGGAGGAGAATGATTTGGGAGGAGAACTTGAGAAAAATTGAGCAACACAACTTTGAGTATTCCTATGGAAATCACACCTTTAAAATGGGAATGAATCAATTTGGTGACATGACAAATGAGGAGTTCAGACAGGCAATGAATGGTTATACGCATGACCCCAACCAGACGTCACAGGGCCCGTTGTTCATGGAACCGAGCTTTTTTGCAGCCCCACAACAGGTTGACTGGAGACAGAGGGGCTATGTTACTCCTGTCAAAGACCAGAAACAATGTGGATCTTGCTGGTCTTTCAGTTCAACGGGTGCCTTGGAAGGTCAGCTCTTCCGTAAAACTGGAAAGCTGATTTCTATGAGTGAGCAAAACTTGGTGGACTGTTCCAGACCACAGGGCAATCAAGGGTGTAATGGAGGCCTCATGGACCAGGCCTTCCAGTATGTTAAAGAAAACAAGGGGCTGGATTCTGAGCAGTCATACCCTTATCTTGCAAGGGATGATCTGCCATGCCGGTATGACCCCCGTTTTAATGTCGCTAAAATCACCGGATTCGTGGACATTCCCAGCGGTAATGAGCTTGCCCTAATGAATGCTGTTGCTGCTGTGGGTCCTGTATCTGTTGCTATTGACGCATCACATCAATCCCTACAGTTCTATCAGTCTGGCATCTATTATGAGAGAGCATGTAGCAGTAGTCGACTTGATCATGCAGTCTTGGTGGTTGGCTATGGTTATCAGGGTGCTGATGTTGCTGGGAATAGATACTGGATTGTGAAGAACAGCTGGTCTGACAAATGGGGTGACAAAGGCTACATCTACAtggcaaaagacaaaaacaatcaCTGTGGCGTTGCGACAAAGGCCAGCTATCCCCTAATGTAAGGTCACTGGAGCCTTCTCTGCATTCTGAAAAAGACACGTTTATGGTTTctctattttaatgtgtttttatttcttctaTTTTATCAAGTTGTTCTGCTGTTAGGGCTATGATAGTGGTATTTTAGGAAATTCCATTTTTCTTGTGtttcatatattttgtttatcCAAGAAGAAGAATTTTGTACTGGATCTATTTGACCTGCAAAtggataaataataaattttctgGCATGGC

Function


symbol description
ctslb Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in immune response and proteolysis involved in cellular protein catabolic process. Predicted to act upstream of or within proteolysis. Located in extracellular region. Is expressed in several structures, including hatching gland; hatching gland cell; hypoblast; mesoderm; and swim bladder. Human ortholog(s) of this gene implicated in hypertrophic cardiomyopathy. Orthologous to several human genes including CTSL (cathepsin L).

GO:

id name namespace
GO:0006955 immune response biological_process
GO:0006508 proteolysis biological_process
GO:0051603 proteolysis involved in cellular protein catabolic process biological_process
GO:0005764 lysosome cellular_component
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0004197 cysteine-type endopeptidase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008233 peptidase activity molecular_function
GO:0008234 cysteine-type peptidase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-980526-285 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in immune response and proteolysis involved in cellular protein catabolic process. Predicted to act upstream of or within proteolysis. Located in extracellular region. Is expressed in several structures, including hatching gland; hatching gland cell; hypoblast; mesoderm; and swim bladder. Human ortholog(s) of this gene implicated in hypertrophic cardiomyopathy. Orthologous to several human genes including CTSL (cathepsin L).

Ensembl:

ensembl_id ENSDARG00000039173

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00010118 False 1351 mRNA 0.44 8 16617138 16619757
TCONS_00010119 True 1248 mRNA 0.44 7 16617140 16619449

Neighbor


gene id symbol gene type direction distance location
XLOC_005260 BX465840.1 coding downstream 18281 16598743 ~ 16598857 (-)
XLOC_005259 si:dkey-239j18.2 coding downstream 21732 16592408 ~ 16595406 (-)
XLOC_005258 FO704724.2 coding downstream 44829 16572195 ~ 16572309 (-)
XLOC_005257 si:dkey-269i1.4 coding downstream 59032 16555603 ~ 16558106 (-)
XLOC_005256 HTR7 coding downstream 92411 16522472 ~ 16524727 (-)
XLOC_005262 si:dkey-239j18.3 coding upstream 14685 16634442 ~ 16636627 (-)
XLOC_005263 BX465840.2 coding upstream 34924 16654681 ~ 16654795 (-)
XLOC_005264 ctslb coding upstream 71827 16691584 ~ 16720434 (-)
XLOC_005265 BX322603.1 coding upstream 123295 16743052 ~ 16746547 (-)
XLOC_005266 zgc:174154 coding upstream 139215 16758972 ~ 16764751 (-)
XLOC_005255 CABZ01044816.1 non-coding downstream 123670 16493352 ~ 16493468 (-)
XLOC_005250 NA non-coding downstream 757269 15857732 ~ 15859869 (-)
XLOC_005247 NA non-coding downstream 1166880 15445574 ~ 15450258 (-)
XLOC_005269 BX000534.2 non-coding upstream 281888 16901645 ~ 16901759 (-)
XLOC_005272 NA non-coding upstream 322447 16942204 ~ 16943248 (-)
XLOC_005273 NA non-coding upstream 344899 16964656 ~ 16966808 (-)

Expression



Co-expression Network