tbk1 (tbk1)


Basic Information

Item Value
gene id tbk1
gene name tbk1
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047612.1
NCBI id CM018558.1
chromosome length 23372418
location 11773891 ~ 11795925 (-)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026923205.2
CACGTGACCGTGTGGCGTCACAGGCGAAAACGGAAGAGGATATCGTGCGCCTGGGGTTCCTCTGAAGAAGATCATCATGCAGAGTACGACAAACTACCTGTGGTTGATCTCGGACCTGCTGGGCCAAGGGGCCACAGCCAACGTGTACCGTGGCAGGCACAAGAAAACGGGTGACCTCTATGCCGTCAAGGTCTTCAACAACCTGAGCTTCCTGCGGCCTCTGGACGTGCAGATGAGAGAGTTTGAGGTGCTAAAGAAACTCAACCACAAGAACATCGTCAAGCTTTTCGCCGTTGAGGAGGAGTCAAACACACGTCACAAGGTCTTGGTTATGGAATACTGTCCATATGGCAGTCTCTACACAGTACTGGAGGAGCCATCTAATGCTTACGGTCTCCCTGAAGATGAGTTCCTCATCGTGCTGCAGGATGTTGTGGCTGGAATGAACCACCTGCGGGAGTACGGAATAGTCCACCGAGACATTAAGCCAGGGAACATCATGCGAGTAATTGGAGAAGATGGACGCTCTGTATACAAACTTACAGATTTCGGGGCGGCGAGAGAGCTAGAAGATGATGAACAATTTGTGTCATTGTACGGAACAGAGGAGTACTTGcatCCAGACATGTATGAGCGAGCTGTGTTGAGAAAAGATCACCAGAAGAAGTACGGAGCCACAGTGGACCTATGGAGCATTGGAGTCACGTTCTACCACGCAGCTACTGGCAGCCTGCCGTTCCGACCTTTCGAAGGACCTCGAAGGAACAAGGAAGTTATGTATAAGATTATTACCGAGAAGCCCTCAGGAGCCATCTCAGGACAGCAGAAGTTTGAGAATGGCAAGATCGAGTGGAGCACAGAGATGCCAGTGTCCTGCAGCCTCTCCAAAGGCCTACAAAGTCTGCTAACCCCAGTTCTGGCCAACATATTGGAGGCAGACCAGGAGAAGTGCTGGGGATTTGACCAGTTCTTTGCAGAGACGAGCGACATCCTGCACCGCACAGTGGTTTACGTCTTCAGCCTGCAGCAAGCCACGCTACACCACGTCTACATCCACACGTATAACACagcCACACTTTTTCAGGAACTGCTCTTCAGACGCACCAACATCAGCCCTCCCAATCAGGAGCTCCTGTATGAGGGCCGACACCTCATGCTGGACCCCAACAGACAGGCGCAGACATTCCCACGTACCAGCAGGGACAATCCCATCATGCTCCTCAGCAGAGAACTTGTCAACACCGTTGGGCTTATCTTTGAAGACCcaagcCCTCCTAAAGTGCAGCCACGGTACGATTTGGACTTGGATGCCAGCTATGCTAAGACATTTGCCGGTGACGTGGGCCACCTGTGGAAAACCTCTGAGTCGTTACTCGTCTATCAGGAGTTGGTGAGGAAAGGAGTGAGGGGTCTCATagAGTTGATGAAAGAGGACTTCAATGAGGCGGCACATAAGAAAGCTGAGGTTTTCCACATGTGTAACCACTGCAATCAAACCCTGGAGAAGACTGAAAAGCTatGTGCAACTTTAATGCAGGGAAATATGTTATCAGCCGAATATGATGAAATCCTGGACTTACACAAGAAAGTGATGAGACTGTCTAACTCACTAAGCTCCATGGATCAGACCATGCAAGACCTCAAAAACAAATTCCTTCCTGGAGGAATGCTGACAGATACATGGACACAGCAAGTGGGCACACACCCTGAAGACAGAAACGTGGAGAAAATCAAAGTTCTTCTTGACGCCATTACAGCCATCTATCAGCAGTTCAAGAAGGACAAAGCTGAACGACgCCTACCTTACAATGAAGAACAAATCCACAAATTCGACAAGCAGAAGCTGGTGTTTCATGCCACCAAAGCCCGTGCCCTGTTCACAGACGAGTGTGCAATGAAGTATCGGCTCTTCATCTCCAAGAGCGAGGAGTGGATGAGGAAGGTGCATCAAGTTAGAAAGCAGCTGCTGTCACTGAACAAACAGTTTCTCAatatggaacaggaagtgaccgTGATCATGCAGCGTGTGTACAAGattcAGGAACAGCTCCCACAGAAGATCATGCCCATTGCGTCAAGTGGCATCAAGCCCCAGGCTTACCTCAGCCAGAGCACTCTCGTGGAAATGACAGCgggGATGAAGAAATTGAAagaggagatggaaggagtaGTCAAAGAACTGGCAGAAAACAATCTCTTTCTGGAGAGGTTTGGCACTCTGACAGTAGATGGTGGGCTGAGAAATGTGGACAGAATCTGAGAGCACAGCACGGCTACAAGACAGCACTGTTTAAAGAAATAGttcagacaaaaatgaaaatggtgtGCATTGCATTTTTGGttaaactattcctttaaagcCAAGGTTTATTTTGAAGGGATAAATAAGATTGccaaatatatatttctgtatatatgttaatgtaaatacTGATCATCTagagagattttatttcactgtctttccttttcttaATTATATCTGTAAGTTAAATAAGAGATGCCTGCTTTTAAGCCTGATGACCTGCTTATCTTGACGTCCATCCATCTGTGCTTGTACccagttcatttttttccctgcactTAATATTTCTAAGGCGCATACAACCTTCGGATAATTAGACTGTACTGTATTCGTCTCTGAATGCTGCACATGTGCAACATTAAAGACTGCAAACCTGc
>XM_026923206.2
aaaaaaaaaaacaccatgtcGAATTGGCCGCATGAAGTTTTTTGTTGGTTGTGTTGGGAATTTCCCACAGTCGTGACGTCACTCTGTAACCCAATCCACCAGCCTGGGCTTTGAATCTCTTCTTTTATCACTTAATCTTTTATCTTCTTTTATCACTTAGCATATCTGAAGCACAATCAGTTCTGATCTGCTCATATTAATTAACTAGCCTAGTAAGCTGAAAGAGTAAGAAATGTGGTGAAAAGACATCAAGAAACTGCTAGAAGGTTCCTCTGAAGAAGATCATCATGCAGAGTACGACAAACTACCTGTGGTTGATCTCGGACCTGCTGGGCCAAGGGGCCACAGCCAACGTGTACCGTGGCAGGCACAAGAAAACGGGTGACCTCTATGCCGTCAAGGTCTTCAACAACCTGAGCTTCCTGCGGCCTCTGGACGTGCAGATGAGAGAGTTTGAGGTGCTAAAGAAACTCAACCACAAGAACATCGTCAAGCTTTTCGCCGTTGAGGAGGAGTCAAACACACGTCACAAGGTCTTGGTTATGGAATACTGTCCATATGGCAGTCTCTACACAGTACTGGAGGAGCCATCTAATGCTTACGGTCTCCCTGAAGATGAGTTCCTCATCGTGCTGCAGGATGTTGTGGCTGGAATGAACCACCTGCGGGAGTACGGAATAGTCCACCGAGACATTAAGCCAGGGAACATCATGCGAGTAATTGGAGAAGATGGACGCTCTGTATACAAACTTACAGATTTCGGGGCGGCGAGAGAGCTAGAAGATGATGAACAATTTGTGTCATTGTACGGAACAGAGGAGTACTTGcatCCAGACATGTATGAGCGAGCTGTGTTGAGAAAAGATCACCAGAAGAAGTACGGAGCCACAGTGGACCTATGGAGCATTGGAGTCACGTTCTACCACGCAGCTACTGGCAGCCTGCCGTTCCGACCTTTCGAAGGACCTCGAAGGAACAAGGAAGTTATGTATAAGATTATTACCGAGAAGCCCTCAGGAGCCATCTCAGGACAGCAGAAGTTTGAGAATGGCAAGATCGAGTGGAGCACAGAGATGCCAGTGTCCTGCAGCCTCTCCAAAGGCCTACAAAGTCTGCTAACCCCAGTTCTGGCCAACATATTGGAGGCAGACCAGGAGAAGTGCTGGGGATTTGACCAGTTCTTTGCAGAGACGAGCGACATCCTGCACCGCACAGTGGTTTACGTCTTCAGCCTGCAGCAAGCCACGCTACACCACGTCTACATCCACACGTATAACACagcCACACTTTTTCAGGAACTGCTCTTCAGACGCACCAACATCAGCCCTCCCAATCAGGAGCTCCTGTATGAGGGCCGACACCTCATGCTGGACCCCAACAGACAGGCGCAGACATTCCCACGTACCAGCAGGGACAATCCCATCATGCTCCTCAGCAGAGAACTTGTCAACACCGTTGGGCTTATCTTTGAAGACCcaagcCCTCCTAAAGTGCAGCCACGGTACGATTTGGACTTGGATGCCAGCTATGCTAAGACATTTGCCGGTGACGTGGGCCACCTGTGGAAAACCTCTGAGTCGTTACTCGTCTATCAGGAGTTGGTGAGGAAAGGAGTGAGGGGTCTCATagAGTTGATGAAAGAGGACTTCAATGAGGCGGCACATAAGAAAGCTGAGGTTTTCCACATGTGTAACCACTGCAATCAAACCCTGGAGAAGACTGAAAAGCTatGTGCAACTTTAATGCAGGGAAATATGTTATCAGCCGAATATGATGAAATCCTGGACTTACACAAGAAAGTGATGAGACTGTCTAACTCACTAAGCTCCATGGATCAGACCATGCAAGACCTCAAAAACAAATTCCTTCCTGGAGGAATGCTGACAGATACATGGACACAGCAAGTGGGCACACACCCTGAAGACAGAAACGTGGAGAAAATCAAAGTTCTTCTTGACGCCATTACAGCCATCTATCAGCAGTTCAAGAAGGACAAAGCTGAACGACgCCTACCTTACAATGAAGAACAAATCCACAAATTCGACAAGCAGAAGCTGGTGTTTCATGCCACCAAAGCCCGTGCCCTGTTCACAGACGAGTGTGCAATGAAGTATCGGCTCTTCATCTCCAAGAGCGAGGAGTGGATGAGGAAGGTGCATCAAGTTAGAAAGCAGCTGCTGTCACTGAACAAACAGTTTCTCAatatggaacaggaagtgaccgTGATCATGCAGCGTGTGTACAAGattcAGGAACAGCTCCCACAGAAGATCATGCCCATTGCGTCAAGTGGCATCAAGCCCCAGGCTTACCTCAGCCAGAGCACTCTCGTGGAAATGACAGCgggGATGAAGAAATTGAAagaggagatggaaggagtaGTCAAAGAACTGGCAGAAAACAATCTCTTTCTGGAGAGGTTTGGCACTCTGACAGTAGATGGTGGGCTGAGAAATGTGGACAGAATCTGAGAGCACAGCACGGCTACAAGACAGCACTGTTTAAAGAAATAGttcagacaaaaatgaaaatggtgtGCATTGCATTTTTGGttaaactattcctttaaagcCAAGGTTTATTTTGAAGGGATAAATAAGATTGccaaatatatatttctgtatatatgttaatgtaaatacTGATCATCTagagagattttatttcactgtctttccttttcttaATTATATCTGTAAGTTAAATAAGAGATGCCTGCTTTTAAGCCTGATGACCTGCTTATCTTGACGTCCATCCATCTGTGCTTGTACccagttcatttttttccctgcactTAATATTTCTAAGGCGCATACAACCTTCGGATAATTAGACTGTACTGTATTCGTCTCTGAATGCTGCACATGTGCAACATTAAAGACTGCAAACCTGc

Function

symbol description
tbk1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in peptidyl-serine phosphorylation. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in brain disease and frontotemporal dementia and/or amyotrophic lateral sclerosis-4. Orthologous to human TBK1 (TANK binding kinase 1).

NR:

description
serine/threonine-protein kinase TBK1-like

GO:

id name namespace
GO:0006468 protein phosphorylation biological_process
GO:0005515 protein binding molecular_function
GO:0005524 ATP binding molecular_function
GO:0004672 protein kinase activity molecular_function

KEGG:

id description
K05410 TBK1; TANK-binding kinase 1

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026923205.2 False 2682 mRNA 0.48 21 11773891 11795925
XM_026923206.2 True 2893 mRNA 0.46 21 11773891 11795414

Neighbor

gene id symbol gene type direction distance location
gpr19 gpr19,LOC107707975,LOC107710070,LOC107658992,LOC107662212 coding downstream 4972 11760781 ~ 11768919 (-)
snap91b LOC108279885,LOC108443062 coding downstream 134160 11610133 ~ 11639731 (-)
LOC117599572 LOC108279885 coding downstream 152703 11618064 ~ 11621188 (-)
atp6v1e1b atp6v1e1,atp6v1e1b,LOC108442797,LOC103026244,LOC107583987,LOC107658907,LOC100708725,LOC102784574 coding downstream 172486 11596768 ~ 11601405 (-)
ada2b LOC108279883 coding downstream 177314 11589813 ~ 11596577 (-)
ptpro ptpro coding upstream 69867 11865792 ~ 11925507 (-)
syn3 syn3,LOC108279673,LOC108412895 coding upstream 193219 11989144 ~ 12081771 (-)
LOC113532343 NA coding upstream 287201 12083126 ~ 12093099 (-)
LOC113532368 NA coding upstream 301596 12097521 ~ 12108662 (-)
LOC113532307 LOC108279675 coding upstream 314318 12110243 ~ 12122771 (-)
G281102 lrp6,LOC102306404,LOC101476287 non-coding downstream 62907 11707690 ~ 11710984 (-)
G281075 NA non-coding downstream 184204 11589003 ~ 11589687 (-)
G281070 NA non-coding downstream 190254 11583393 ~ 11583637 (-)
G281057 NA non-coding downstream 211827 11561725 ~ 11562064 (-)
G281021 NA non-coding downstream 414255 11359362 ~ 11359636 (-)
G281362 NA non-coding upstream 237171 12033096 ~ 12036362 (-)
G281373 NA non-coding upstream 297932 12093857 ~ 12094059 (-)
G281455 NA non-coding upstream 455389 12251314 ~ 12254155 (-)
G281486 NA non-coding upstream 573034 12368959 ~ 12369265 (-)
G281510 LOC108279795,LOC108442313 non-coding upstream 661638 12457563 ~ 12459092 (-)
dusp16 dusp16 other downstream 20978 11721063 ~ 11752913 (-)
G281092 mansc1 other downstream 113564 11657890 ~ 11660327 (-)
G281074 rad51ap1 other downstream 185867 11586304 ~ 11588024 (-)
vegfab vegfa,LOC108435123 other downstream 514479 11238935 ~ 11259412 (-)
sobpb LOC108279441 other downstream 679715 11079168 ~ 11094176 (-)
LOC113531972 muc19,LOC108280038 other upstream 3344000 15139925 ~ 15184075 (-)
alg12 alg12 other upstream 4604996 16400921 ~ 16406863 (-)
LOC113532230 LOC108280029,LOC107562148,LOC107687569,LOC107741714,LOC105912408 other upstream 5042610 16838535 ~ 16853395 (-)
phf21b phf21b other upstream 5162587 16958512 ~ 17027865 (-)
LOC113532261 smkr1 other upstream 6182838 17978763 ~ 17988280 (-)

Expression


Co-expression Network