mettl3 (mettl3,LOC107659734,LOC107595277)


Basic Information

Item Value
gene id mettl3
gene name mettl3,LOC107659734,LOC107595277
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047598.1
NCBI id CM018544.1
chromosome length 33267568
location 13245985 ~ 13251814 (+)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026935834.2
GCCGGCTTTCAGTTTCCGGTACATGGCGGAAGTTTAGTGCCTGTGTTTGATGCAGGAGTTTGTTAACTGTTTGTTGGCGCCACTAAAGCGAGTATTTGAATCATTTAGTCATTAAGTATCCTTCAGTTTGAGTTTAAGATGTCAGATACATGGAGCGACATTCAGGCACACAAAAAGAAGCTGGACTCTCTGAGAGAGAGGctgcagaggaggaggaaagatCCAACACAGCTGGGTATCGAggttggtggtggtgatggggCACCCACACGCAGTGACAGTCCAGGGCCAACCCTCCAAACCCCCacagagatggaggaggagcGTCCCCCTGACCCTGAATTAGAGAGAAGACTTCTGGAATACCTGTCCGAACTGAGCCTCACACTCCCCACTGACTCTCTGGCCATCACCAACCAGCTCAACTCTTCTGAATCACCAGTATCACACGCCTGCATCCAGAGTCTTCTACTTAAATTTTCGGCTCAGGAATTGATCGAAGTCCGACAGCCAACCAACAATACCTCGTCTTCGTCCTCGTCTTCATCCACCTTAGTTGTCTCTGTCGATCATACCAAACTGTGGGCAATGATTAGTAGTTCCACACCACAACCTCAGAAAGCTGgtgtgaaaagaaaaggagatgATATTATTCACCAAAAGAGGGCTCCTGGCTCCTCCCCTTTGCTTCAGTCGTCTTCTTCGCCATCCAAAACATCATCTACCTCTTCTGCTTCCAGTTCACAGCTGGCTgggacttctgattggaagtCGGGATCTGGAGGAGTTGGGGCTGAGAAAAAGGGCCGAACCAATAAGGGAAAGACGTCTCACTTGGATATGGAGATAGAGAGCTTATTGAGTCAGCAGTCAACCAAggagcaacaaaacaaaaaggtgagcaGGGAAATCCTTGAGTTACTGAACACTAGCTCGGCCAGGGAGCAGTCCATTGTAGAGAAATTTCGTTCACGGGGTCGAGCACAGGTGCAGGAATTCTGCGATCATGGGACTAAGGAGGAGTGCATGCGATATGGAGACACCCCACAACCCTGCAACAAGCTGCATTTCAGGCGGATCATCAACAAGCACACAGACGAGAGTCTTGGAGACTGCTCCTTCCTGAACACCTGTTTCCACATGGACACCTGTAAATATGTACACTACGAGATTGACAGCCCACCTGAAGCCGAGAGCGGCTCCACGGGACCTCAGCCCGGCACCACTGAGCTCACTCTGCATGCTAGAGACGGAGACAGCAATGTGGGGAAACTGTTTCCAGCTCAGTGGATCTGTTGTGATATCCGCTACCTGGATGTGTCCATCCTGGGGAAGTTTGCGGTGGTGATGGCTGACCCTCCATGGGACATTCACATGGAGCTTCCATATGGAACTCTGACAGATGATGAGATGAGGAAACTTAACATTCCTATTCTGCAGGATGATggcttcctcttcctctgggTGACTGGAAGAGCAATGGAGCTTGGCAGAGAGTGTCTAAGCCTCTGGGGGTATGAGCGTGTTGATGAGATCATTTGGGTGAAGACCAATCAGCTCCAGCGTATTATTCGGACAGGACGGACTGGACACTGGCTGAACCACGGCAAAGAGCACTGCttgGTAGGAGTGAAAGGAAACCTTCAAGGATTCAACAGAGGCCTGGACTGTGATGTGATTGTCGCAGAGGTGCGTTCTACCAGTCACAAACCAGATGAGATCTATGGAATGATTGAGCGTTTGTCTCCTGGCACTAGGAAGATTGAACTGTTTGGGAGGCCCCATAATGTCCAACCAAACTGGGTAACTTTGGGGAATCAGTTGGATGGAATTCATTTGTTGGACCCTGATGTAGTAGCACGTTTTAAAAAGCGCTATCCAGATGGAGTCATTTCCAAACCCAAAAACATGTGAAGACATACCCAGCTCACAGTGACTGCTACATGTTCAGTCTTCTCAGAGACTTTCAGGATCATTTAAATGCGGGAAATCTTTTGTATTgtcaatcatttttaataaaacaactaggtgaatta
>XM_034303705.1
CGCCGGCTTTCAGTTTCCGGTACATGGCGGAAGTTTAGTGCCTGTGTTTGATGCAGGAGTTTGTTAACTGTTTGTTGGCGCCACTAAAGCGAGTATTTGAATCATTTAGTCATTAAGTATCCTTCAGTTTGAGTTTAAGATGTCAGATACATGGAGCGACATTCAGGCACACAAAAAGAAGCTGGACTCTCTGAGAGAGAGGctgcagaggaggaggaaagatCCAACACAGCTGGAggttggtggtggtgatggggCACCCACACGCAGTGACAGTCCAGGGCCAACCCTCCAAACCCCCacagagatggaggaggagcGTCCCCCTGACCCTGAATTAGAGAGAAGACTTCTGGAATACCTGTCCGAACTGAGCCTCACACTCCCCACTGACTCTCTGGCCATCACCAACCAGCTCAACTCTTCTGAATCACCAGTATCACACGCCTGCATCCAGAGTCTTCTACTTAAATTTTCGGCTCAGGAATTGATCGAAGTCCGACAGCCAACCAACAATACCTCGTCTTCGTCCTCGTCTTCATCCACCTTAGTTGTCTCTGTCGATCATACCAAACTGTGGGCAATGATTAGTAGTTCCACACCACAACCTCAGAAAGCTGgtgtgaaaagaaaaggagatgATATTATTCACCAAAAGAGGGCTCCTGGCTCCTCCCCTTTGCTTCAGTCGTCTTCTTCGCCATCCAAAACATCATCTACCTCTTCTGCTTCCAGTTCACAGCTGGCTgggacttctgattggaagtCGGGATCTGGAGGAGTTGGGGCTGAGAAAAAGGGCCGAACCAATAAGGGAAAGACGTCTCACTTGGATATGGAGATAGAGAGCTTATTGAGTCAGCAGTCAACCAAggagcaacaaaacaaaaaggtgagcaGGGAAATCCTTGAGTTACTGAACACTAGCTCGGCCAGGGAGCAGTCCATTGTAGAGAAATTTCGTTCACGGGGTCGAGCACAGGTGCAGGAATTCTGCGATCATGGGACTAAGGAGGAGTGCATGCGATATGGAGACACCCCACAACCCTGCAACAAGCTGCATTTCAGGCGGATCATCAACAAGCACACAGACGAGAGTCTTGGAGACTGCTCCTTCCTGAACACCTGTTTCCACATGGACACCTGTAAATATGTACACTACGAGATTGACAGCCCACCTGAAGCCGAGAGCGGCTCCACGGGACCTCAGCCCGGCACCACTGAGCTCACTCTGCATGCTAGAGACGGAGACAGCAATGTGGGGAAACTGTTTCCAGCTCAGTGGATCTGTTGTGATATCCGCTACCTGGATGTGTCCATCCTGGGGAAGTTTGCGGTGGTGATGGCTGACCCTCCATGGGACATTCACATGGAGCTTCCATATGGAACTCTGACAGATGATGAGATGAGGAAACTTAACATTCCTATTCTGCAGGATGATggcttcctcttcctctgggTGACTGGAAGAGCAATGGAGCTTGGCAGAGAGTGTCTAAGCCTCTGGGGGTATGAGCGTGTTGATGAGATCATTTGGGTGAAGACCAATCAGCTCCAGCGTATTATTCGGACAGGACGGACTGGACACTGGCTGAACCACGGCAAAGAGCACTGCttgGTAGGAGTGAAAGGAAACCTTCAAGGATTCAACAGAGGCCTGGACTGTGATGTGATTGTCGCAGAGGTGCGTTCTACCAGTCACAAACCAGATGAGATCTATGGAATGATTGAGCGTTTGTCTCCTGGCACTAGGAAGATTGAACTGTTTGGGAGGCCCCATAATGTCCAACCAAACTGGGTAACTTTGGGGAATCAGTTGGATGGAATTCATTTGTTGGACCCTGATGTAGTAGCACGTTTTAAAAAGCGCTATCCAGATGGAGTCATTTCCAAACCCAAAAACATGTGAAGACATACCCAGCTCACAGTGACTGCTACATGTTCAGTCTTCTCAGAGACTTTCAGGATCATTTAAATGCGGGAAATCTTTTGTATTgtcaatcatttttaataaaacaactaggtgaatta

Function

symbol description
mettl3 Enables mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity and mRNA (N6-adenosine)-methyltransferase activity. Involved in endothelial to hematopoietic transition and regulation of hematopoietic stem cell differentiation. Acts upstream of or within several processes, including Notch signaling pathway involved in arterial endothelial cell fate commitment; hematopoietic stem cell proliferation; and oocyte maturation. Predicted to be located in cytoplasm. Predicted to be part of RNA N6-methyladenosine methyltransferase complex. Predicted to be active in nuclear speck. Is expressed in several structures, including gill; heart; liver; nervous system; and pleuroperitoneal region. Used to study infertility. Orthologous to human METTL3 (methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit).

NR:

description
PREDICTED: N6-adenosine-methyltransferase 70 kDa subunit

GO:

id name namespace
GO:0080009 mRNA methylation biological_process
GO:0005634 nucleus cellular_component
GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity molecular_function

KEGG:

id description
K05925 METTL3; mRNA m6A methyltransferase catalytic subunit

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026935834.2 True 2036 mRNA 0.49 11 13245986 13251814
XM_034303705.1 False 2031 mRNA 0.49 11 13245985 13251814

Neighbor

gene id symbol gene type direction distance location
trip6 trip6,LOC103041331 coding upstream 3585 13232634 ~ 13242400 (+)
kdm6ba kdm6b,LOC106608825 coding upstream 47436 13116216 ~ 13198549 (+)
dnah2 dnah2 coding upstream 130818 12980849 ~ 13115167 (+)
serpinh2 LOC108267141,LOC108412061 coding upstream 269548 12951069 ~ 12976437 (+)
efnb3b efnb3,efnb3b,LOC107597046,LOC106577756 coding upstream 384768 12795941 ~ 12861217 (+)
agfg2 LOC108267520,LOC108442826 coding downstream 60066 13311880 ~ 13327219 (+)
si:ch73-335l21.1 LOC108267519,LOC105020633 coding downstream 76219 13328033 ~ 13375050 (+)
si:ch73-335l21.2 LOC108268347,LOC108442822 coding downstream 139995 13391809 ~ 13394172 (+)
dvl2 dvl2 coding downstream 147621 13399435 ~ 13416861 (+)
acadvl acadvl,LOC107738021,LOC107595296,LOC107731915 coding downstream 168719 13420533 ~ 13436596 (+)
G63666 NA non-coding upstream 46123 13199007 ~ 13199862 (+)
G63696 NA non-coding upstream 110125 13135659 ~ 13135860 (+)
G63685 NA non-coding upstream 126308 13119468 ~ 13119677 (+)
LOC117596991 NA non-coding upstream 318998 12922870 ~ 12926987 (+)
G63547 NA non-coding upstream 411655 12801894 ~ 12834330 (+)
LOC117597082 NA non-coding downstream 7060 13258874 ~ 13267034 (+)
G63889 NA non-coding downstream 135784 13387598 ~ 13387954 (+)
G63901 NA non-coding downstream 165407 13417221 ~ 13417441 (+)
G63898 NA non-coding downstream 207548 13459362 ~ 13467726 (+)
G63936 NA non-coding downstream 252646 13504460 ~ 13504719 (+)
tmem88b tmem88,bcl6b,LOC108267673 other upstream 26126 13206657 ~ 13219859 (+)
si:dkey-112a7.4 LOC108268066 other upstream 950852 12292491 ~ 12295133 (+)
si:ch211-200p22.4 LOC108267499,LOC108434851 other upstream 1540649 11644901 ~ 11705336 (+)
LOC117596972 LOC108267738,LOC108267932,LOC108267931,LOC108267739,LOC108267937,LOC108261673,LOC108267938,LOC108267933,LOC108267935,LOC108267740 other upstream 1640755 11590715 ~ 11605230 (+)
c4h4orf48 c7h4orf48 other upstream 2582574 10657357 ~ 10663411 (+)
slc16a13 slc16a13 other downstream 23648 13275462 ~ 13285834 (+)
G63903 NA other downstream 166563 13418377 ~ 13418696 (+)
LOC113539889 LOC108267838 other downstream 216738 13468552 ~ 13475037 (+)
cited1 cited1 other downstream 306809 13558623 ~ 13562266 (+)
gc2 LOC108267421,LOC108412585 other downstream 453603 13705417 ~ 13719454 (+)

Expression


Co-expression Network