serpine1 (serpine1,LOC101154654)


Basic Information

Item Value
gene id serpine1
gene name serpine1,LOC101154654
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047598.1
NCBI id CM018544.1
chromosome length 33267568
location 17747955 ~ 17751639 (-)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026936054.2
AGCTCATGCTTGACAGGCAGATCCAGAAGAACAGTCTGCAAGGTTAACTCATTGGAAGAGCCTACAAAACCTACTCAGGATGCAGAGACTGTGTGTACTGGTGATTCTCACCTTTTGTGGGTCAGCTCTGGGTAACCTCCTACAGAAGCAGCAGACAGATTTTGGACTACGTGTGTTTTCAGAAGCTGCCCAATCCCATCCACATCAAAATCTCATTCTGTCTCCTTATGGCATCTCCTCAATGCTGGGGATGGCTCAGCTGGGAGCCAAGGGTGCCACTTTTCAGACTCTCAAACAACACATGGGCTACTCTCTGCGAGATCGTGGAATGTCACGTCAACAGAGGCTTCTTCAGAGAGACCTGGCCAGTGAAGAAGGAGTGGAAGTGGCGAGTGCCATAATGGTAGACAGGAAGGTAGTCTTGGAGAAAATCTTCCGACGTAGCCTATTAAAGGCATTTCAGAGTGTGCCACACCAGGTGGACTTCAGTCATCCTGACAGTGCCCTGGAGGTCATCAACTCCTGGATGTCAGACAACActggagGCATGATCCCAAATTTCCTACAACCTGGAGTGCTGAGTGACCAGACACGTTTGTTGCTGTTGAATGCCCTCCACTTCCATGGGCTTTGGAAGAACCCTTTTGACCCTAGGCTGACTGCAGAGGCGACCTTCCACACAGCTAATGGCAGTGCAGTGTCAGTGTCAATGATGAGATCAACACAGAAGTTCAACTACGGTGAGTTTGTTACACAGGACGGCATTGAATATGATGTTATTGAGGTGCCATACGCAGGGGACTCACTGAGCATGCTCATTGTATCGTCATTTGAGAGGGATGTACCACTTTCTGCCCTAACCGGAGAGCTGAGCAGCAACAAAATCCAAGAATGGAGAGAGCAGTTGAGGAAGGTTAACCGAGAGCTGGTGATTCCCagGTTTTCCTTAGACACAGAAGTCGATCTGAAGTCAGCACTGAGTAAACTGGGTCTTGGCAAAATCTTCAGTCAGACTGAGGCTGATTTCTCCCGCATTACTACTGATGAGCCATTGTATGTATCAAAGATTTTACAGCGAGTAAAGTTTGAGGTGAATGAAGAGGGAACCAAAGGATCTTCTGCTGGAGGTGTCATCATCTACTCTCGCATGGCCATAACAGAGCATATTTTGAACCGTCCATTCCTCTTCCTTGTACAGCACAAGCCAACAGGTGCTGTGCTATTCACGGGTCAAGTGAACCAACCTCAGAATCATTAGCAATCCCAGAAGCACAAAGACTAAGAAGATTACTGTCACTCTCTTCAAAGAAATTACTACTGAGTCAGTGCAGGTTTGGGAACAAGATAAAGAAGCAATAATCTTACATGCAACCTGGAGACCACTAGAAGGTGTACTTAACGTAAGCCTCCAAACAAAAGGATCAATAAGTTTGAAGAAGATTTCCTAAATTTAAGTCCTTTGTTTGACTGGAAGGTCTCTCATCACTAACTGGAAATTATATATCAGTAAagacagtatagtgtagtgtgtgtgtggaggaagacaTTGTAAAAACTATTTGTCAATGAAGGAAAACACCTGTGTAgtttaaaacacaacaaatgttACTATTGCTGTAGGATTATATTGGCACtttttaaatacagacagaTTTATAAAAGCCATTATcccatttttataattaaaaaagcaGTATTctgaaacaatatttttaacCTGCAAGGACAAGGTGATGTATGAAATTTGCTAGGGAATATTTTGATATCATGATGTTTactttacatattatatttaatgcaaagttgtattttttttaagacatatatttatttctatatgaAGACTTTTATTTGTGTGAAGATGGCATATTTGTACATGGAGcataataaactataataataaacatacttTATAATGAAAAA
>XM_026936055.2
GAAGAAATTTGCTGAGACTCAGCTCATGCTTGACAGGCAGATCCAGAAGAACAGTCTGCAAGGTTAACTCATTGGAAGAGCCTACAAAACCTACTCAGCAGGATGCAGAGACTGTGTGTACTGGTGATTCTCACCTTTTGTGGGTCAGCTCTGGGTAACCTCCTACAGAAGCAGCAGACAGATTTTGGACTACGTGTGTTTTCAGAAGCTGCCCAATCCCATCCACATCAAAATCTCATTCTGTCTCCTTATGGCATCTCCTCAATGCTGGGGATGGCTCAGCTGGGAGCCAAGGGTGCCACTTTTCAGACTCTCAAACAACACATGGGCTACTCTCTGCGAGATCGTGGAATGTCACGTCAACAGAGGCTTCTTCAGAGAGACCTGGCCAGTGAAGAAGGAGTGGAAGTGGCGAGTGCCATAATGGTAGACAGGAAGGTAGTCTTGGAGAAAATCTTCCGACGTAGCCTATTAAAGGCATTTCAGAGTGTGCCACACCAGGTGGACTTCAGTCATCCTGACAGTGCCCTGGAGGTCATCAACTCCTGGATGTCAGACAACActggagGCATGATCCCAAATTTCCTACAACCTGGAGTGCTGAGTGACCAGACACGTTTGTTGCTGTTGAATGCCCTCCACTTCCATGGGCTTTGGAAGAACCCTTTTGACCCTAGGCTGACTGCAGAGGCGACCTTCCACACAGCTAATGGCAGTGCAGTGTCAGTGTCAATGATGAGATCAACACAGAAGTTCAACTACGGTGAGTTTGTTACACAGGACGGCATTGAATATGATGTTATTGAGGTGCCATACGCAGGGGACTCACTGAGCATGCTCATTGTATCGTCATTTGAGAGGGATGTACCACTTTCTGCCCTAACCGGAGAGCTGAGCAGCAACAAAATCCAAGAATGGAGAGAGCAGTTGAGGAAGGTTAACCGAGAGCTGGTGATTCCCagGTTTTCCTTAGACACAGAAGTCGATCTGAAGTCAGCACTGAGTAAACTGGGTCTTGGCAAAATCTTCAGTCAGACTGAGGCTGATTTCTCCCGCATTACTACTGATGAGCCATTGTATGTATCAAAGATTTTACAGCGAGTAAAGTTTGAGGTGAATGAAGAGGGAACCAAAGGATCTTCTGCTGGAGGTGTCATCATCTACTCTCGCATGGCCATAACAGAGCATATTTTGAACCGTCCATTCCTCTTCCTTGTACAGCACAAGCCAACAGGTGCTGTGCTATTCACGGGTCAAGTGAACCAACCTCAGAATCATTAGCAATCCCAGAAGCACAAAGACTAAGAAGATTACTGTCACTCTCTTCAAAGAAATTACTACTGAGTCAGTGCAGGTTTGGGAACAAGATAAAGAAGCAATAATCTTACATGCAACCTGGAGACCACTAGAAGGTGTACTTAACGTAAGCCTCCAAACAAAAGGATCAATAAGTTTGAAGAAGATTTCCTAAATTTAAGTCCTTTGTTTGACTGGAAGGTCTCTCATCACTAACTGGAAATTATATATCAGTAAagacagtatagtgtagtgtgtgtgtggaggaagacaTTGTAAAAACTATTTGTCAATGAAGGAAAACACCTGTGTAgtttaaaacacaacaaatgttACTATTGCTGTAGGATTATATTGGCACtttttaaatacagacagaTTTATAAAAGCCATTATcccatttttataattaaaaaagcaGTATTctgaaacaatatttttaacCTGCAAGGACAAGGTGATGTATGAAATTTGCTAGGGAATATTTTGATATCATGATGTTTactttacatattatatttaatgcaaagttgtattttttttaagacatatatttatttctatatgaAGACTTTTATTTGTGTGAAGATGGCATATTTGTACATGGAGcataataaactataataataaacatacttTATAATGAAAAA

Function

symbol description
serpine1 Enables serine-type endopeptidase inhibitor activity. Acts upstream of or within negative regulation of plasminogen activation. Predicted to be active in extracellular space. Is expressed in heart. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); diabetic retinopathy (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human SERPINE1 (serpin family E member 1).

NR:

description
plasminogen activator inhibitor 1-like

GO:

id name namespace
GO:0006955 immune response biological_process
GO:0010951 negative regulation of endopeptidase activity biological_process
GO:0010757 negative regulation of plasminogen activation biological_process
GO:0005615 extracellular space cellular_component
GO:0004867 serine-type endopeptidase inhibitor activity molecular_function
GO:0008009 chemokine activity molecular_function

KEGG:

id description
K03982 SERPINE1, PAI1; plasminogen activator inhibitor 1

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026936054.2 False 1923 mRNA 0.42 9 17747955 17751619
XM_026936055.2 True 1946 mRNA 0.42 9 17747955 17751639

Neighbor

gene id symbol gene type direction distance location
ap1s1 ap1s1,LOC105921790,LOC107666294,LOC103148860,LOC107593725,LOC108443977 coding downstream 820 17737776 ~ 17747135 (-)
LOC113539922 snapc2 coding downstream 96035 17648230 ~ 17651920 (-)
ache ache,LOC108267799,LOC107668174,LOC107593784,LOC107750572,LOC107749789 coding downstream 194815 17540590 ~ 17553140 (-)
zgc:92664 cssa04h17orf49,clg07h17orf49,LOC108267800,LOC108434657,LOC103038770,LOC107561866,LOC107594707,LOC107668195,LOC107678180,LOC105902403,LOC105027650 coding downstream 211182 17533165 ~ 17536773 (-)
cd99l2 cd99l2 coding downstream 404673 17329547 ~ 17343282 (-)
zgc:77439 LOC108268285,LOC108443975,LOC107666303,LOC107561800,LOC107750567,LOC107669018 coding upstream 13509 17765148 ~ 17769886 (-)
trnas-uga NA coding upstream 19511 17771150 ~ 17771231 (-)
gal3st4 gal3st4,LOC108443973,LOC107593694 coding upstream 91515 17843154 ~ 17853369 (-)
her8a her8a,LOC108267186,LOC108262021,LOC107750660,LOC107563304,LOC107754663,LOC107666285 coding upstream 116988 17868627 ~ 17870914 (-)
LOC113539930 LOC108268343 coding upstream 123528 17875167 ~ 17880384 (-)
G66318 NA non-coding downstream 46701 17696777 ~ 17701254 (-)
G66311 NA non-coding downstream 60857 17686886 ~ 17687098 (-)
G66310 NA non-coding downstream 61721 17686021 ~ 17686234 (-)
G66274 NA non-coding downstream 109969 17571331 ~ 17637986 (-)
G66349 NA non-coding upstream 47483 17799122 ~ 17812526 (-)
G66350 NA non-coding upstream 50027 17801666 ~ 17809014 (-)
G66355 NA non-coding upstream 112371 17864010 ~ 17864883 (-)
G66387 NA non-coding upstream 263505 18015144 ~ 18020809 (-)
G66651 NA non-coding upstream 634922 18386561 ~ 18386990 (-)
G66281 NA other downstream 113087 17593748 ~ 17634868 (-)
rnaseka LOC108267746 other downstream 303767 17439477 ~ 17444188 (-)
G66053 NA other downstream 345491 17400594 ~ 17402464 (-)
bmp15 LOC108267203 other downstream 1142238 16603809 ~ 16605717 (-)
leap2 LOC100304644 other downstream 1153450 16592562 ~ 16594505 (-)
map11 c7h7orf43,cunh7orf43,si:dkey-3k24.5,LOC107687048,LOC107594676,LOC107754664,LOC107561780,LOC105895567 other upstream 40587 17792226 ~ 17839915 (-)
LOC113540242 adamtsl1 other upstream 1298511 19050150 ~ 19155221 (-)
zgc:112271 bola2,LOC105907194,LOC108436240,LOC105020731,LOC107569065,LOC106511278 other upstream 2128329 19879968 ~ 19881640 (-)
G67587 NA other upstream 2136540 19888179 ~ 19888726 (-)
LOC113539792 LOC108267751,LOC108440128 other upstream 2167841 19919480 ~ 19943834 (-)

Expression


Co-expression Network