foxc1a (foxc1,foxc1a,LOC107726170,LOC106532673,LOC101078665)


Basic Information

Item Value
gene id foxc1a
gene name foxc1,foxc1a,LOC107726170,LOC106532673,LOC101078665
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047598.1
NCBI id CM018544.1
chromosome length 33267568
location 6202522 ~ 6204890 (+)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026947472.2
aggcagagaaGGGAAAGAAATGAACGTGCACGAAAAAAGTCCCGCGTCTTGACGGATGCCCTGAAGTTCAGAAAGTTTTTCCAATGCGCGCTTCGgcgaagagaaagagagtgaaagagtgagcgAGGTGGCTGCAGAGACAGTACCGAGGCCCTGGACGAGAGCTGAACATTTTGTGGACTTTTTACTCTCCTtggactctttttttttcttttaaagctaGGAAAAGAAACTTAAAGTGGATTTGTGCCGTTTCGGATCTCTCGGTGGTGCTTTTCGGTCGTCGGCGGAATAATCACCATGCAGGCGCGCTACTCGGTGTCGAGCCCTAACTCTCTGGGCGTCGTGCCGTACATTAGCGGCGAGCAGAGCTACTATCGCGCGGCGGCGGCCGGCGGCGGCTACGCGGGCATGGCGGCGCCCATGAGCATGTACTCGCACGCCGCGCACGAGCAGTACCCGGGCGGCATGGCGCGGGCGTACGGGCCGTACGCGCCTCAGCCGCAGCCCAAGGACATGGTCAAGCCGCCGTACAGCTACATCGCGCTCATCACCATGGCCATCCAGAACTCTCCGGATAAGAAGATCACCCTGAACGGGATCTATCAGTTCATCATGGAGCGCTTCCCCTTCTACCGGGACAACAAGCAAGGCTGGCAGAACAGCATTCGCCATAACCTGTCGCTCAACGAGTGCTTCGTTAAAGTTCCGCGCGATGACAAGAAGCCGGGTAAGGGCAGCTACTGGACGCTTGACCCGGACTCGTACAACATGTTTGAGAACGGCAGCTTCCTGCGACGGCGGCGTCGCTTCAAGAAGAAGGACGCTCTGAAAGAGAAGGAAGACCGGCAGATCAAGGAGGCCACGTCCTCTCGCCAGCagccgcagcagcagcagcaacagggCCGCGAGCAGCAGGAGCCGACTGCTGCGCCACCAGTGCGCATTCAGGACATCAAGACGGAGAACGGTGCGTGCACGCCGCCGCAGGCCGTGTCACCCGCGCTCGGTGCGGTTCCCAAGATCGAGAGCcctgacagcagcagcagtagcatgTCAAGCGGCAGCCCGCACAGCGTGCCGTCATCTTCAGCTCGCTCCGTGGGCCTGGACGGCGGCGGTGCTGGAGagccgcagcagcagcagcagcagcagcagcatcacgCACACCACCAGCAACAACACCCACACCACGGCCACGGGCACGCGCAGGGCTTCAGCGTGGACAACATCATGACCTCGTTGCGCGGCTCGCCGCAGGGCGCCGGGGACCTCACGCCGTCTCTCGCGGCCTCCACGCGGACAGGTATAAGCCCTTCGTTGTCCCTTAACTACTCGCCGAGCCAGGCGGCCGCGTACAGCTCGCCCTGCAACCAGAGCGCCGTCTCCACTACCTCGCACGCCACCTACCACTGCAACATGCAGGCCATGAGCTTGTACGCGGCGGAGCGCGCCGGCACCACCGCCGCCAGCACCACCTCGGTGGACGAGACTTTGCCCGACTACTCCATCACGACCACCGCCGCCTCGTCGTCCTCGCTGGGCCACGCCGGCCACCTTGGCTCAGGCCAGGAGGGACACCATCCTCACTCGCATCAGGGCCGCCTCGCCTCGTGGTACCTGAACCAGGCCGGAGACCTGGGCCACCTCGGCGCCACCTACCCGACACAGCAGCAGAACTTTCACTCGGTGCGAGAAATGTTCGAGTCACAGCGGATCGGCTTGAATAACTCCCCGGTGAACGGAAATAACAGCTGTCAGATGTCCTTTCCTTCCAGCCAGTCCATATACCGCGCGTCTGGGGCTTTTGTCTACGACTGCAGCAAGTTCTGACCAAAAGTCCACTTTTGTgcgatatttttttttttatattttatttccccCTCAtttcccctttctttttttctccataaacAGAGAATCTTTGATACTTATTACCCTCTCCTCGCCATGgactgaacacacaaacacatggtgTGGGTTTATTATGGACAGTGTTACTGCAAATAACACGTAAGTCTCCTTTTTCGCTTTTGCGAGCTATatgctttgctttaaaaaaaaaaaaaaacaagaaagacaaagaaaaaaaaaacgccagcTTTTCACGGACTTGTTATTACGTGTAAATTGCATATagtaatttatttctgaaatgtaaCCGGAATATTATGGACCAAACACCCGAACCGTTTTGTTTCTAAAACTGAGTTGCCTTTAATTGTGCAGAAATGTTCCATTATAACAAGGGAACAGAAACGTGTATATCGCAATATTCATTCAAATTATCTcattttgttgaaaaaaaaaagtattctgaAGGATCTGCattctttgtttaataaattaccATTTTATTTGAGTTAAA

Function

symbol description
foxc1a Enables chromatin binding activity. Acts upstream of or within with a positive effect on vascular associated smooth muscle cell differentiation. Acts upstream of or within several processes, including animal organ development; regulation of signal transduction; and vasculature development. Predicted to be located in nucleus. Is expressed in several structures, including cardiovascular system; head; mesenchyme; mesoderm; and somite. Human ortholog(s) of this gene implicated in several diseases, including eye disease (multiple); lymphedema; lymphedema-distichiasis syndrome; obesity; and type 2 diabetes mellitus. Orthologous to several human genes including FOXC1 (forkhead box C1).
foxc1 Enables DNA binding activity, bending; DNA-binding transcription activator activity, RNA polymerase II-specific; and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; odontogenesis of dentin-containing tooth; and positive regulation of cell differentiation. Acts upstream of or within eye development; heart development; and positive regulation of transcription, DNA-templated. Located in cytosol; heterochromatin; and nucleoplasm. Implicated in Axenfeld-Rieger syndrome; Axenfeld-Rieger syndrome type 3; anterior segment dysgenesis 3; and glaucoma. Biomarker of congestive heart failure and invasive ductal carcinoma.

NR:

description
PREDICTED: forkhead box C1-A

GO:

id name namespace
GO:0006351 transcription, DNA-templated biological_process
GO:0003677 DNA binding molecular_function

KEGG:

id description
K09396 FOXC; forkhead box protein C

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026947472.2 True 2368 mRNA 0.55 2 6202522 6204890

Neighbor

gene id symbol gene type direction distance location
foxf2a LOC108267118 coding upstream 25363 6171029 ~ 6177159 (+)
foxq1a LOC108268192 coding upstream 38682 6162153 ~ 6163840 (+)
trnat-ugu_1 NA coding upstream 63150 6139300 ~ 6139372 (+)
irf4a irf4a,LOC108267998,LOC107565529 coding upstream 165290 6014920 ~ 6037232 (+)
dusp22b dusp22,LOC103368952,LOC100701332 coding upstream 192738 5991928 ~ 6009784 (+)
wrnip1 wrnip1 coding downstream 346095 6550985 ~ 6572077 (+)
LOC113547283 NA coding downstream 367178 6572068 ~ 6576902 (+)
dhx30 dhx30 coding downstream 375465 6580355 ~ 6602411 (+)
LOC113547232 LOC108262378 coding downstream 439638 6644528 ~ 6683316 (+)
LOC113547277 NA coding downstream 503491 6708381 ~ 6713301 (+)
G60036 NA non-coding upstream 303532 5897899 ~ 5898990 (+)
G60033 NA non-coding upstream 348634 5853669 ~ 5853888 (+)
G60029 NA non-coding upstream 359448 5842775 ~ 5843074 (+)
G59993 NA non-coding upstream 475081 5726602 ~ 5727441 (+)
G59990 NA non-coding upstream 476854 5725446 ~ 5725668 (+)
G60232 NA non-coding downstream 3212 6208102 ~ 6208314 (+)
LOC117596998 NA non-coding downstream 72715 6277605 ~ 6295446 (+)
G60267 NA non-coding downstream 91101 6295991 ~ 6296234 (+)
LOC117596997 NA non-coding downstream 96435 6301325 ~ 6305562 (+)
G60312 NA non-coding downstream 175355 6380245 ~ 6380462 (+)
trnat-ugu_2 NA other upstream 58720 6143532 ~ 6143802 (+)
LOC113547291 LOC108268023 other upstream 606297 5579796 ~ 5596225 (+)
LOC113547289 LOC108267851 other upstream 810693 5388368 ~ 5391829 (+)
LOC113547261 LOC108262218,LOC108267254,LOC108261847,LOC108268075 other upstream 1012809 5179554 ~ 5189713 (+)
G59492 LOC108268230,LOC108268219 other upstream 1187709 4974195 ~ 5014813 (+)
LOC117597080 NA other downstream 390236 6595126 ~ 6596601 (+)
LOC113547228 NA other downstream 479446 6684336 ~ 6704346 (+)
LOC113526345 LOC108268111,LOC103023736,LOC105899422,LOC108436874,LOC101065160 other downstream 1851166 8056056 ~ 8062839 (+)
LOC117597156 NA other downstream 2490462 8695352 ~ 8724440 (+)
LOC113539869 LOC108267273,LOC108267272,LOC108267212,LOC108267213,LOC108267290,LOC108261494,LOC108267722 other downstream 2519655 8724545 ~ 9370485 (+)

Expression


Co-expression Network