hand2 (hand2)


Basic Information

Item Value
gene id hand2
gene name hand2
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047597.1
NCBI id CM018543.1
chromosome length 33776708
location 3802564 ~ 3805829 (+)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026933871.2
TTCGAGCAGCACAACATGAAGCTGCGACTCACACATCAAACGGAGAAAAAATCCACATGAGAGCTGCACAAACACAACTGCAACAGTGTATGGAAACTTTCTCGTTTGGTTTTTGTGTCCAGCAGGGATTTGTGGCTCGGACACACTCACATGACCGAGAGATTGTCTGAGATGACTTTCTCAGCCTGCACTGGTTTCTAATGGGACGTTTGCTCGTGCTGGGATGTGCACTATGGAGCCTGCACGCGAGTAAGTAGGTGACTTTCAGAAGTTCTAAACACATTTCAGGTCCACTGTCTAAAATATGTGTTGCTTGGTATCAGTTCTCCATTGTGTGATGGACAGATAGAGCCTGATTCATTTCACCGACCCAGGAAGAACGAGTGTTGCACGACtactcctttttttattttcacggCAAGTCGATGATCGCTACAAAACATAGGTACAATCTGAGAGAgtgagggggggaaaaaaaggaaaaaattaaatacagaagAGCAAAAGCGCGCTCTGTTTTTGCAGGACTTTATCATGAGTTTGGTAGGAGGCTTTCCTCACCACCCGGTCGTGCACCATGACGGCTACTCGTCCTCCTTCGCCGCAGCAGCCGCAGCCGCAGCCGCCGCGAGCCGCTGTCATGAGGAAAGCCCTTATTTCCACGGGTGGCTCATCGGGCACGCGGACATGTCGCCGCCGCCGGACTACGGCATGGCGCCTTCGTCCTACAGCCCCGAGTACACCGCCAATAACGCCGCCGGCGGTGTGTGCGCGCCCGGGCCTGGCTTGGAGCACGGGCCCTACGGAGCAGGCGGCGCGGGAGCACTCGTACCGGGCATGATGGTGGTGCCGCGCGCCGTGAAGCGGAGGCCCACGGCGAACCGGAAGGAGAGACGCAGGACTCAGAGCATCAACAGCGCGTTCGCCGAGCTGCGCGAGTGCATCCCTAACGTGCCCGCAGACACCAAGCTGTCCAAGATAAAAACATTGCGCCTCGCTACCAGCTACATCGCCTACCTCATGGACATCCTGGACAAACACGAGCAGCACGGCGGCGGCGAGACGGAGGCCTTCAAGGCCGAGTTCAGGAAGGCGGACTccaaagaggagaggaggaagaaagaaacgAATGAAGTTTTGAAATGTTCAGGGAGCAGCAATGACAAGAAACCCAAAGGGAGAACTGGTTGGCCGCAACACGTCTGGGCTTTGGAACTGAAACagtgaacttaaaaaaaacacctttgaATTGAGGCCTTtccttgtcatgtttttttacaCTAACTTTATTTAATGGAATATTTATGTGCAATTTCTACGGACAGTGGATCCttgaagacaaaacaaaaacaaaaaaaaaacattccagtttTAAGAGGAGGATGCCCCTCTTGGTAAGggattgtgttgttgttgttgttgctattgTTGTCTAGTTTGTGGTGAATGTCTGCCACTAAAGTGAAAGTGTaggtctctctctttctcgctccaTTTCTCtgaatagaaaaaatatatcaaatgaGCGGTCGAGGAAGTTCTGAAACAGTTTGAAACAACGTTTtatttggagaaagaaaaaaaaaacacaaatgtcaTGAAGTGTTATGTTGTGATGTTTTGTTGTGGTCGTATATATAGGAATCTCTCTGGTCGTGTTTGAAACCTAATGTTGAGTCCACTCAAGTGCACTTCCGTCCAGACACCagaagtttataaaaaaaaaataataataataaatatctgaaGATGTAAACGATGTAATTAATTCAATAAACCACTGTGTTTTAAATGA

Function

symbol description
hand2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including animal organ development; determination of intestine left/right asymmetry; and nervous system development. Predicted to be located in nucleus. Is expressed in several structures, including cardiovascular system; digestive system; head; mesoderm; and pectoral fin. Orthologous to human HAND2 (heart and neural crest derivatives expressed 2).

NR:

description
heart- and neural crest derivatives-expressed protein 2

GO:

id name namespace
GO:0003342 proepicardium development biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0003142 cardiogenic plate morphogenesis biological_process
GO:0003144 embryonic heart tube formation biological_process
GO:0071908 determination of intestine left/right asymmetry biological_process
GO:0035118 embryonic pectoral fin morphogenesis biological_process
GO:0030859 polarized epithelial cell differentiation biological_process
GO:0010002 cardioblast differentiation biological_process
GO:0030878 thyroid gland development biological_process
GO:0048703 embryonic viscerocranium morphogenesis biological_process
GO:0060047 heart contraction biological_process
GO:0005634 nucleus cellular_component
GO:0003677 DNA binding molecular_function
GO:0046983 protein dimerization activity molecular_function

KEGG:

id description
K18486 HAND2; heart-and neural crest derivatives-expressed protein 2

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026933871.2 True 1795 mRNA 0.48 2 3802564 3805829

Neighbor

gene id symbol gene type direction distance location
fbxo8 fbxo8,LOC107670846,LOC107752227 coding upstream 89728 3700579 ~ 3712836 (+)
hpgd hpgd,LOC107752225,LOC107552502,LOC107737128,LOC107676678,LOC107558775 coding upstream 134072 3644478 ~ 3668492 (+)
glra3 glra3,LOC106610166,LOC107670853,LOC106602381,LOC107752223,LOC106935306 coding upstream 160816 3572427 ~ 3641748 (+)
gpm6ab gpm6a,gpm6ab,LOC107670876,LOC107737106,LOC107752222,LOC107676686 coding upstream 299444 3434345 ~ 3503120 (+)
LOC113541773 NA coding upstream 426448 3373213 ~ 3376116 (+)
hmgb2a hmgb2,hmgb2a,LOC107752228,LOC107670798,LOC102792727,LOC100707400 coding downstream 32897 3838726 ~ 3840862 (+)
scpp1 LOC108262830 coding downstream 677719 4483548 ~ 4487275 (+)
tnip2 tnip2 coding downstream 689803 4495632 ~ 4500384 (+)
prmt9 prmt9 coding downstream 1077167 4882996 ~ 4892379 (+)
si:dkey-27h10.2 NA coding downstream 1794056 5599885 ~ 5626477 (+)
G40287 NA non-coding upstream 117359 3683343 ~ 3685205 (+)
LOC117596918 NA non-coding upstream 277443 3515101 ~ 3525121 (+)
LOC117596855 NA non-coding upstream 399458 3400795 ~ 3403106 (+)
G38962 NA non-coding upstream 1371477 2427812 ~ 2431087 (+)
G38948 NA non-coding upstream 1375964 2411201 ~ 2426600 (+)
G40374 NA non-coding downstream 58867 3864696 ~ 3865000 (+)
G40586 NA non-coding downstream 324286 4130115 ~ 4130322 (+)
G40590 NA non-coding downstream 421364 4227193 ~ 4227431 (+)
G40591 NA non-coding downstream 422353 4228182 ~ 4228548 (+)
G40592 NA non-coding downstream 423563 4229392 ~ 4229622 (+)
stox2a stox2,stox2a,LOC108434127,LOC107559650,LOC107550915,LOC107748824,LOC107671062,LOC107684970 other upstream 1711221 2025488 ~ 2091343 (+)
cdk2ap2 cdk2ap2 other upstream 1805299 1983647 ~ 1997265 (+)
sh3gl2a sh3gl2,LOC107595059,LOC107714635,LOC107757631,LOC107700329 other upstream 2577963 1194219 ~ 1224601 (+)
trmo trmo other upstream 2613970 1165845 ~ 1188594 (+)
coro2a coro2a other upstream 2660630 1102778 ~ 1141934 (+)
LOC113545357 NA other downstream 26038 3831867 ~ 3834626 (+)
nr3c2 nr3c2,LOC107598757 other downstream 858487 4664316 ~ 4771604 (+)
znf827 znf827 other downstream 1457753 5263582 ~ 5357860 (+)
G41047 NA other downstream 1512705 5318534 ~ 5341750 (+)
inpp4b inpp4b,LOC107703845,LOC107657998 other downstream 2089602 5895431 ~ 6228685 (+)

Expression


Co-expression Network