calm2a (calm1,LOC102293206,LOC102778633,LOC107396020)



Basic Information


Item Value
gene id calm2a
gene name calm1,LOC102293206,LOC102778633,LOC107396020
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information


Item Value
chromosome id NC_047597.1
NCBI id CM018543.1
chromosome length 33776708
location 21569456 ~ 21574081 (-)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence


>XM_026935733.2
GTTTCATAGCGACCATTAAAGGCGCGCCAGGCACTCTCCTATTGCATCCTGTTTGTTTGCCAGCTGCGAACTGTTGGACTTGTGGAACTACATTTTATTAACCAGCGCGATGGCCGACCAGCTGACAGAGGAGCAGATTGCCGAGTTCAAAGAGGCATTCTCACTCTTTGACAAGGATGGAGATGGCACCATTACGACCAAAGAGTTGGGTACTGTCATGCGTTCTCTTGGTCAGAACCCAACAGAGGCTGAGCTGCAGGACATGATCAATGAAGTGGATGCTGATGGAAATGGGACGATAGACTTCCCTGAGTTCCTGACAATGATGGCAAGGAAGATGAAGGACACAGACAGTGAGGAGGAGATCAGGGAAGCATTCCGTGTCTTCGATAAGGACGGGAACGGATACATCAGTGCTGCTGAGCTGCGTCATGTGATGACAAACCTGGGAGAGAAGCTAACTGATGAGGAGGTCGATGAGATGATCAGAGAAGCAGACATTGATGGAGATGGACAGGTGAACTATGAAGAGTTCGTACAGATGATGACGGCAAAGTGAAAGCCCTGTACagatcctctctctctttctctcctataaataatttgcctttttttgtttaatttatctGTAAAACGTTAAGTCCCCCCTCTTCCTCCCGGCTGTCCAAAGGAACTGCATGTAAACTGCATAGGATCTAACTCCTCATGTCCCTTTCTTTTGCTGTCATCGTGTTTTTTGGAGTGACGGTGCGGTTACACGATCAGGTGCTTGTTGCGGCGATACGGGGGCGGTGGCGCGCAAAACCCTGCACGTCACATCTGTCTGCCCCCCACCCGATGCGTAGCAAGAGCGGAGACCTGTCAGCTGGCTTGCCACCCGGCAACAATGTTGGCAGGGCAACAATGTAGAGGAGTAACTCTGCATGGACTATGGAcaaagtatataatatatatgaaattTATCAGCATTGCActactgcaaaagaaaaaaatatattaaaaaaaaaaaaaagacacggGTGTATCTTCTAGATACTCGTACATAAACTCTTTTTGTATCTGCTGTTCTGTACCAGAGAACTTGTTTGAATCTTATGAtgcttttaatggtttattcactttcactttttttttttttttttttttttttttttttaaaaacagcttaACATCATTGTCATGCCTCAAATAATCCATTCCaagttgtatatttttgttttccaaTAAAATTTACAACCCAGAATTGAAAGGTTTCCTTGTTTGTAGAGCATCCTTAAGCCCTTGAGAACGCGAAGCTCTTGAGTATGTTGGCCGTTATGCATCCCTGAGctgattttagttttattttttttttgggtttattattttttttaagtggtttCAATCCACTTACATCAACCAGAATGTTTACAATTATTGTAGTAGAAATTGTTCATTTGTAAATCATCATACAATGTATCTCTGAGTCAACTGGTCAAATTACTATGTGTAATCACAGGATAGGATCGGGGGTACGGCCTCCTTGTCAAAGCAAAATAAACGTTCATTAAAGTACTCTTAAAAA

Function


symbol description
calm1 Enables several functions, including N-terminal myristoylation domain binding activity; enzyme activator activity; and enzyme binding activity. Involved in several processes, including positive regulation of hydrolase activity; regulation of calcium ion transmembrane transport; and regulation of heart contraction. Located in microtubule cytoskeleton and sarcomere. Part of calcium channel complex and catalytic complex. Implicated in catecholaminergic polymorphic ventricular tachycardia 4 and long QT syndrome 14. Biomarker of Alzheimer's disease.

NR:

description
unnamed protein product

GO:

id name namespace
GO:0022400 regulation of rhodopsin mediated signaling pathway biological_process
GO:0001975 response to amphetamine biological_process
GO:0007190 activation of adenylate cyclase activity biological_process
GO:0045087 innate immune response biological_process
GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion biological_process
GO:0051412 response to corticosterone biological_process
GO:0007202 activation of phospholipase C activity biological_process
GO:0005513 detection of calcium ion biological_process
GO:0002027 regulation of heart rate biological_process
GO:0000086 G2/M transition of mitotic cell cycle biological_process
GO:0030168 platelet activation biological_process
GO:0002576 platelet degranulation biological_process
GO:0038095 Fc-epsilon receptor signaling pathway biological_process
GO:0007268 chemical synaptic transmission biological_process
GO:0035307 positive regulation of protein dephosphorylation biological_process
GO:1901841 regulation of high voltage-gated calcium channel activity biological_process
GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction biological_process
GO:0043647 inositol phosphate metabolic process biological_process
GO:0043388 positive regulation of DNA binding biological_process
GO:1901339 regulation of store-operated calcium channel activity biological_process
GO:0008543 fibroblast growth factor receptor signaling pathway biological_process
GO:0051000 positive regulation of nitric-oxide synthase activity biological_process
GO:0048011 neurotrophin TRK receptor signaling pathway biological_process
GO:0032465 regulation of cytokinesis biological_process
GO:0005980 glycogen catabolic process biological_process
GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity biological_process
GO:0032516 positive regulation of phosphoprotein phosphatase activity biological_process
GO:0016310 phosphorylation biological_process
GO:0046209 nitric oxide metabolic process biological_process
GO:0006006 glucose metabolic process biological_process
GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity biological_process
GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity biological_process
GO:0007173 epidermal growth factor receptor signaling pathway biological_process
GO:0034704 calcium channel complex cellular_component
GO:0030426 growth cone cellular_component
GO:0005813 centrosome cellular_component
GO:0000922 spindle pole cellular_component
GO:0005829 cytosol cellular_component
GO:0005576 extracellular region cellular_component
GO:0005876 spindle microtubule cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005654 nucleoplasm cellular_component
GO:0030017 sarcomere cellular_component
GO:0043548 phosphatidylinositol 3-kinase binding molecular_function
GO:0043274 phospholipase binding molecular_function
GO:0017022 myosin binding molecular_function
GO:0031800 type 3 metabotropic glutamate receptor binding molecular_function
GO:0005509 calcium ion binding molecular_function
GO:0008179 adenylate cyclase binding molecular_function
GO:0030235 nitric-oxide synthase regulator activity molecular_function
GO:0019904 protein domain specific binding molecular_function
GO:0050998 nitric-oxide synthase binding molecular_function
GO:0048306 calcium-dependent protein binding molecular_function
GO:0005246 calcium channel regulator activity molecular_function
GO:0072542 protein phosphatase activator activity molecular_function
GO:0031432 titin binding molecular_function
GO:0044325 ion channel binding molecular_function
GO:0016301 kinase activity molecular_function
GO:0031996 thioesterase binding molecular_function
GO:0031997 N-terminal myristoylation domain binding molecular_function

KEGG:

id description
K02183 CALM; calmodulin

RNA


RNA id representative length rna type GC content exon number start site end site
XM_026935733.2 True 1564 mRNA 0.42 6 21569456 21574081

Neighbor


gene id symbol gene type direction distance location
stpg4 NA coding downstream 1214 21562717 ~ 21568242 (-)
mcfd2 mcfd2,LOC105900047,LOC107699287 coding downstream 42679 21522208 ~ 21526777 (-)
epas1b epas1 coding downstream 185340 21348210 ~ 21384116 (-)
srbd1 srbd1 coding downstream 238398 21276785 ~ 21331058 (-)
six2a six2,six2a,LOC107666385,LOC107602488,LOC107602487,LOC107711421 coding downstream 359082 21207017 ~ 21210374 (-)
si:ch73-105b23.6 LOC108262810 coding upstream 3782 21577863 ~ 21602259 (-)
LOC113544981 NA coding upstream 334900 21908981 ~ 21910793 (-)
pkdcca pkdcc coding upstream 606066 22180147 ~ 22204975 (-)
ubr2 ubr2 coding upstream 692615 22266696 ~ 22299362 (-)
LOC113538327 LOC108263699,LOC108420514 coding upstream 726836 22300917 ~ 22317379 (-)
G50626 NA non-coding downstream 51378 21517815 ~ 21518078 (-)
G50624 NA non-coding downstream 53814 21515152 ~ 21515642 (-)
G50619 NA non-coding downstream 56634 21512605 ~ 21512822 (-)
G50433 NA non-coding downstream 183959 21346142 ~ 21385497 (-)
G50318 NA non-coding downstream 352570 21216658 ~ 21216886 (-)
G50647 NA non-coding upstream 32347 21606428 ~ 21610897 (-)
G50656 NA non-coding upstream 85577 21659658 ~ 21737394 (-)
LOC117596829 NA non-coding upstream 193733 21767814 ~ 21786645 (-)
G50802 NA non-coding upstream 307805 21881886 ~ 21882106 (-)
LOC113544235 NA non-coding upstream 319453 21893534 ~ 21899039 (-)
prkceb prkceb,prkce,LOC108263296,LOC108422423,LOC107699301,LOC107727364,LOC107708403 other downstream 90751 21387743 ~ 21478705 (-)
gng2 gbg2,gng2,LOC108239039,LOC106603227 other downstream 1200011 20357934 ~ 20369445 (-)
atp10d atp10d,LOC107556926 other downstream 1312936 20224909 ~ 20256520 (-)
metap1 metap1,LOC107556924 other downstream 1363863 20182053 ~ 20205593 (-)
slc4a11 slc4a11,LOC107695019 other downstream 1801322 19716600 ~ 19768134 (-)
plekhh2 plekhh2 other upstream 37582 21611663 ~ 21645512 (-)
G50837 NA other upstream 375774 21949855 ~ 21950189 (-)
LOC113540944 eml4,LOC107586470,LOC107698167 other upstream 461204 22035285 ~ 22123649 (-)
LOC113541574 LOC108263228 other upstream 991690 22565771 ~ 22571868 (-)
znf318 znf318 other upstream 1200274 22774355 ~ 22788804 (-)

Expression



Co-expression Network