hif1aa (hif1a)


Basic Information

Item Value
gene id hif1aa
gene name hif1a
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047597.1
NCBI id CM018543.1
chromosome length 33776708
location 33306312 ~ 33321663 (-)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026939217.2
ATCACAGTGGCTGATTTTTTGGCACTAAGGTGGTTTTGGTCGAGTGGATGTTATGCGGCTGGCTTCCTGCAGTGGATTGGAGAAAGGAAGTTggagaaataatgaaaatatttgccTCTAAACGTGAGGAATACGGGGGACGTTTGTTGGCCGTTGCCTAGTGACGACTCCGATAAAGAGgctcgcgcgcgcgcgctcacGCGATTCCAGAGAGCGAGCGCGGCTCAGATGACGCTCGAGCGACGCGCGAGACCGAGCCAGCGTCAGTTTGTTTAGCTAAAAGTTTAGCATTTGGACGCGACGTTTTCTGAAACGGTttccttgtttatttatttatttatttattttcgcGGTTTTTTGAAACAATCTCCTTTCTCCACGGGCCACTGAGTTGGTCAGTAATCTCCATAATGACTTCAGGAGCCACAGCTGAAAAGAAAAGacAGAGCTGTGAGCGGAGGAAGGCGAGGTGTCGTGATGCGGCACGCTGTAGGCGGGTGAAGGAGACGGAGGTGTTTAATCAGCTGGCCAATCAGCTTCCTCTCCATCACAGCATCACCGAGAGCCTCGATAAAGCCTCGATCATCCGTCTCACGCTGAGCTACCTGCACCTGCGCTCGGCCCTCAGCACAGTGATGATGGGCGAGCAGTCCGAGTTGGACACTCAGTGGAGCGCTTCCTGTCTGAAGGCCCTCGACGGCTTCCTCATGATTCTCTCTCAGGATGGAGACGTCGTTTACGCTTCAGAAACCGTCAGCAAGTGTCTGGGGATTCCCcagATCGATCTTTCAGGACAGAGTGTGTTTGATTTCACTCACCCCTGTGACCATGAAGAGATCAGAGAGATGCTGGTTAACAGaacaggtTCCTGTAAGAAAACGAGAGATGAGCAGAGTTGCTTGTTGCGCATGAAGTGCACTCTGACCAGCAGGGGGCGCACCGTCAACCTCAGATCTGCTACGTGGAAGGTTCTACACTGTTCCGGTCACATCCGCGTGGAGTGCACGCAGAACAGCGTGTGTGAAGAGAGCGGTACGACGGTGTCATACCTGGTGCTGATCTGTGAACCGATCCCACATCCAGCCAGCATCGAGGTTCTTCTAGACTCCAGAACGTTCCTGAGCAAACACACGCTGGACATGCGCTTCTCCTACTGCGACGAACGgatcaCACAGTTGTTGGGGTATGACCCTGAGGATCTCCTTCAGTGTTCTGTGTACGAGTTTTATCACGCTCTGGACTCGGACAGtctcacaaaaacacaccacaacTtgtttgtgaaGGGCCAGGCATGTACAGGTCAGTACCGTATGCTGGTGAAGGGCGGAGGCTTTGTGTGGGTCGAGACTCAGGCCACCGTcatttacaacaacaaaaactctCAACCGCAGTGTGTCATCTGCCTCAACTAcgtcctcagCGGTGTTGAAGAACCCGAgctcgttctctctctccatcagtcAGCGATAAAGCAGGAGAAGGAGGACGGGTGCgggacggagagagagacacagagccaGGAAGCAGTGACTCGGATAAACGAGGACaggaaagaggagaagagagagggagaaacagagtTACAGGCTGACGCTGACGTCACACTGGACTTCACGAACACAGGGACAGAAACGTCAGTGCTCAAGGACGCTCCTCTCTACAACGACGTCATGCTGCCCTCCACCAGCGTCCTGTCACCTCTGTCTCCGCCCACCGAACCACCCTGCGCCACCCTGCCCCGGCTGGACGACCTCCCCTTCCCATCATCCTCTGCTCCGAACTCGTCCGGTCGCGGTTCCACTCAGGCGGTGGAGGATCTGGAGTTGGAGATGTTAGCTCCCTACATCTCCATGGATAATGATTATCAGCTCcacacgcatgcacacgcaGAGGGTTCAGAGTATCCTCACTCCGGCCAGAAAAACACCAGAAAGCACACAGATCCCAGCGGTACACAGCACAGAGAACAGCCGGATGAAGATCTGTCTTCCGCAAGTCGGTCGAGCCAAAAGAGAAAATTTGAAACGATTTCTCTGCGTCATGCCACAGGgctgGTGGTAACAGACTCACCTCAGGTCAAGAGGTCAAAGGTGACGGTGTCAGAGGCTCGTCCACCAGCCGCCATGCCAGAGACTCTGACTATACTGCTGCTCCCCTCAGACGTGTTAAACCAATTAGTGGTAGGAGGAGCCATCATTAAGCCCCTCCCACACATCACTCTAGGATGTGAAGTTGACGCACCTGTCACTGCGCGGAGAAACCTGCTGCAGGGGGGCGGGAGGAGCTTCGGCACGCACCGCACTGAACCTGcaaaagatttttaatatttaatatatttcatcattttagaGATTTTATACTTTGTCTAATtatatgttattaaatgttactttttattaaatgttacttttactttcctatattttatattattttaaggcatttttgtttaaaccaAAGTGCTCGTTATAGATAATTATAAAACTCATGACTcgttgttttaattttttaactttattagcTATATTTCAACATACAGTCAAATCCATACATGGATACAAGAACCATTCATCTCCTCATACatgaaattatttgaaataagtaattttttaaaaaatatttagattCAAATTTCAATATGTAGAAATTCAAGTGAACAACTGTGATGTGGTGAGATTTTTCGTGTGATTTACGCTAAAGCTAAATCTGCCTCTAACCCCGCCTCTAAACCTACCTCAACCGCTCACTCCTCCTCTAACCAGGCACGAGACGACACGAGACGTATCCCGATACAGGCTTCACGAGACGATAGTGACgcaaatacagtataaaatttTAACGTGTTTATTTTGTAACGACATTAAATCGAATCGCTGTGATATCAGTACATTGTATTGAAggaaaagtagatcaggatttataatataaggtgtaattttcccctattattaacattattttaatattttcagtgccataaatgtatttcatggcaATGTTCCTAATATGGAAAGATGGTTGGACAAGATTAGTTTGTGccttaaatgatgaaatatgaatcaaaaataaaaaagcagtttaATTGTACTGATGAGAAAATAAGAGTGATGTTAGTTTCCTCATCTCACCAAAATGAATTTCTGGTTGCGCCCGCACGTCGTGCTTCTGAATCGTTTCAGACgcgagtgtgacttacatcaagcgcAGCTCACAGGTCGTTGCTTTTAACCTGCGTTTCAGACCACGTTCAAGCCAGCCGTGTCAGAAACCGGGGTGCACATATATACGGTTTACGGTAACTACCTTCGGATGGCTACGCTACAGATCCGCTGTGAATCCTGGACAGTGTGAAAAcgttaaaatattattttttccaagttCACGCGGGTCGAATGAAACGGGGCTGCGAGCCTTGTGTTTGTCACACGTGCCGGAAAGCTTCCTTCGgattagtttcattttttgggCTATCGAGAAGGCAGGCTTCGAGACAGAAATATCGCAGTCCACATCAAAGAAGCAAAATTCGTCTCGCCAGTATTTTGTATCGTGAAATTCTCTCATGCCTACCTCGAACACTAACCCCGCCTCTAATCCTAACCATAACCCTGCCTCTAATCCTAACCATAACCCCACCTCTAATCCTAACCATAACCCCGCCTCTAATCCTAACCATAACCCCGCCTCTAATCCTAACCTAACCCCGCCTCTAATCCTAACCATAACCCGCCTCTAATCCTAACCATAACCCCGCCTCTAATCCTAACCATAACCCCACCTCTAATCCTAACCATAACCCCGCCTCTAATTTTAACACTAACCCCGACTCTaatcctaacactaaccccGCCTCTAATCCTAACACTAAACCCGCCTCTAATCCTAACACTAACCCGCCTCTAATCCTAACACTAAACCCACCTCTaatcctaacactaaccccGCCTCTAATCCTAACCAT

Function

symbol description
hif1a Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; Hsp90 protein binding activity; and enzyme binding activity. Contributes to DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in several processes, including oxygen homeostasis; regulation of gene expression; and vascular endothelial growth factor production. Acts upstream of or within regulation of transcription, DNA-templated and response to hypoxia. Located in chromatin; cytosol; and nuclear body. Part of RNA polymerase II transcription regulator complex. Implicated in lung non-small cell carcinoma; myocardial infarction; prostate cancer; and type 2 diabetes mellitus. Biomarker of several diseases, including arthritis (multiple); invasive ductal carcinoma; kidney cancer (multiple); morbid obesity; and mycosis fungoides.

NR:

description
PREDICTED: hypoxia-inducible factor 1-alpha

GO: NA

KEGG: NA

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026939217.2 True 3961 mRNA 0.47 15 33306312 33321663

Neighbor

gene id symbol gene type direction distance location
LOC113542112 NA coding downstream 12969 33286801 ~ 33293343 (-)
osr1 osr1,LOC108440809,LOC107548611,LOC107588719,LOC107668777,LOC107757107,LOC107675531 coding downstream 202069 33095656 ~ 33104243 (-)
rdh14a rdh14,LOC105895584,LOC104955673 coding downstream 437957 32865245 ~ 32868355 (-)
mtres1 c3h6orf203 coding downstream 541968 32759671 ~ 32764344 (-)
sobpa sobp,LOC107706905,LOC107588585 coding downstream 596101 32669506 ~ 32710211 (-)
prkcha prkch,LOC107707065,LOC107675581,LOC107757130 coding upstream 7342 33329005 ~ 33336795 (-)
dhrs7 dhrs7 coding upstream 35367 33357030 ~ 33361865 (-)
six1a six1,six1b,LOC108263091,LOC108414064,LOC108257556,LOC107697302,LOC107589069,LOC108434988 coding upstream 63451 33385114 ~ 33387819 (-)
six4a NA coding upstream 67830 33389493 ~ 33403724 (-)
tdrd9 tdrd9,LOC104966444 coding upstream 146360 33468023 ~ 33484082 (-)
G57292 NA non-coding downstream 794 33303570 ~ 33305518 (-)
G57290 NA non-coding downstream 7999 33296819 ~ 33298313 (-)
G57275 syt14 non-coding downstream 48520 33257229 ~ 33257792 (-)
G57267 NA non-coding downstream 70600 33234666 ~ 33235712 (-)
G57215 NA non-coding downstream 237627 33067534 ~ 33068685 (-)
G57294 NA non-coding upstream 4417 33326080 ~ 33360691 (-)
G57300 NA non-coding upstream 41941 33363604 ~ 33364547 (-)
G57302 ppm1a,LOC106571506 non-coding upstream 43394 33365057 ~ 33410771 (-)
G57224 NA non-coding upstream 48197 33369860 ~ 33375501 (-)
G57232 NA non-coding upstream 49112 33370775 ~ 33406126 (-)
G57210 NA other downstream 206740 33019278 ~ 33099572 (-)
G57124 pdss2,LOC102782659 other downstream 577571 32715827 ~ 32728741 (-)
slc66a3 pqlc3 other downstream 644700 32653836 ~ 32661612 (-)
ndufaf1 ndufaf1,LOC107588570 other downstream 917168 32374336 ~ 32389144 (-)
tmem39b tmem39b,LOC107675583,LOC107705392 other downstream 951812 32346755 ~ 32354500 (-)
slc38a6 slc38a6 other upstream 15740 33337403 ~ 33344836 (-)
lrrc9 LOC108262921 other upstream 102001 33423664 ~ 33442815 (-)
G57322 NA other upstream 133559 33455222 ~ 33462342 (-)
mycla LOC108263077 other upstream 158685 33480348 ~ 33524819 (-)
trnag-gcc_5 NA other upstream 208264 33529927 ~ 33529997 (-)

Expression


Co-expression Network