sirt1 (sirt1)


Basic Information

Item Value
gene id sirt1
gene name sirt1
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047597.1
NCBI id CM018543.1
chromosome length 33776708
location 25365115 ~ 25386138 (+)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026939297.2
ATTTCCTGGGCTTGGTGGCCTAAACGCGCATTTAAAAGATGGCGGACACGGAACATAAATCGGTCGCCGATTGTGATAGAACAAGCGAGCCGGTCCGTAAGAAATCACGGAGTAGTGTTCTTCAGAACTGTGGTCCAGACGCTATTAACGGAGGTCAAGTAACAAGTGGAGACCAGTTAGGTGGGAGTTGTGCGGTGGAGATTTCGGTACGGCCCGAAGATGCAGAACCGGAGATGGGGGTGGCTCAGGCCACAGAGGGTGCACAAGAAAACAGCAATGAGCCTGTGACCTCGGAGCTCACAAAAGATTACGCTAATGCAGATAAGACTCTAATGTCTGGACCTGAAAGTGAGGTGTTAGGGTTAATGGACGATGATATTCACCGCAATGGATTTTATTCACCTGAGTTAGGTGATGATGAGGACTGCTCTTCTCATGCCAGTTCTAGTGACTGGACTCCCCAGCCACGTATTGGTTCTTACCGCTTTATTCAGCAACAAATAATGAGAGAGACTGATCCACGGACTATTCTAAATGACCTGCTTCCAGACACTGCCATTCCACCAGATCTTGATGACATGACACTATGGCAGATTGTCATCAACATCTCGGAGCCTCCAAAGAGAAAGAAACGCAAAGATATTAACACCATAGAGGATGTCATCAGACTGCTTCATGATTCCAAAAAGATACTTGTCCTGACTGGTGCTGGGgtttctGTTTCCTGTGGAATACCTGATTTTAGGTCTAGAGATGGGATTTATGCTCGACTTGCTGTTGATTTTCCAGACCTTCCAGATCCTCAAGCAATGTTTGATATTGAGTACTTCCGAAGGGATCCAaggccattttttaaatttgcgaAGGAAATCTACCCTGGACAATTTCGGCCATCACTTTGTCACAGATTTATTGCTATGCTGGATAAGAAAGAGAAGATTCTCAGGAACTACACTCAGAACATTGACACTCTGGAGCAGGTTGCGGGAGTCCAAAGGGTCATGCAGTGTCATGGTTCCTTTGCAACTGCATCCTGCCTTGTGTGTAAACACAAAGTTGATTGTGATGCCATAAGGGAAGATATATTCAGACAGGTTGTTCCCCATTGTCCAAAGTGCTCTAATATCCCTTTCGCTATTATGAAACCAGACATCGTCTTCTTTGGTGAGAACCTTCCAGAAGCTTTTCATAGGGCCATGAAGCAGGACAAGGATGAGGTGGATCTCCTCATTGTTATTGGATCCTCTTTGAAAGTGCGACCAGTGGCTCTTATCCCAAgCGCTGTTCCCCATGAAGTGCCTCAAGTTTTGATCAACCGTGAGCCCCTGCTTCACTTGAACTTTGACGTAGAACTGCTAGGAGACTGTGATGTCATTGTCAACGAATTATGTCACCGACTGGGTGGTGACTTTGAGGAGCTTTGCTACAACTCTTCTCGACTAAGTGAGATCACAGACTTGCCGCCTCCTCTGCCAACTACTCTACCTGAACAGGCATGTGCTAAAGTCCAAACATCTGAAGTTCAAAATACAGGACACTTTTTCACAAAACAAGATGAGACAGTTGCAGAAACATCGGAGACAGTAACAGTTATAGACTCTTGTCCAAGTGCACAGTTCCCAAATGTTGGGGATTTGAACACATCTTGTACATCCAAAGAAGCAAGACCCTCTTCAGAGCTAGAAAACAGATCAAGCTCACCAAAACCTTCAACACAAGAAAATGATGGGTGTCCTAATGCACAGCCAAGGCCCTCCCAAAAGAGCTCAGATGCCTATCAGAATGCACCATTGGAGGCTGTTAGAAATAGTCCACATATAcaacaagagagagaggggataaTGGAGATGCTGGATATGCAAATTGAAGAGAAgcataaaaatcaaacaaatgatGTCGGCAAACGATGCTGGCTTAAACAGATCTGTCGAAATCCAATCAGTAATCGCCTTGGAACTTCCCAATACTTGTTTCAGGCTCCGAATCGTTACATTTTCCATGGAGCTGAAGTGTACTCCTGCTCAGAAGATGAGACATCCAGTTCCTCTGACAATGAGGGCTCCTGCTGCAGTGGCAGTGGTTTAGAGGAACAAGAAAGCGATGCAGAGGAGGAATGCACACCTGGCGACTGTCCAAGACCTGGGGAAGGTGGTGTTGGAGAGACAGGGGATGAAAATACATACATgtcaaacattcacacacacagtataatgGAGAATCTCGACACACAATGACAGACCTCTAAAATATGGTCTCCCTGTTCTCTATAAGTACTATGTATAGGTTTTGTGCTTACTTCTGTTTGagactgtatatttttgtactCTCCTGCCGCCAGTCCCACCCTTGTACTGTTACAGCGTGCTCCAAGTCTCTTTGGACGGGGAATTCACAGtagtgttttttattgtttattcagttttgaTTAGAGATGAAAGGTTGATGGATTCAAAGTATTGGTTACTTGTATTAAggtatttcaatattttatatgtGCTGCATTATTTTGGTTGTATAGCTCTTGTGTCCAGTCCCCCATTTGATGAACATATGTTTGGAtaaattaagttaatgtcaATTTA

Function

symbol description
sirt1 Predicted to enable several functions, including NAD+ binding activity; NAD-dependent histone deacetylase activity; and p53 binding activity. Acts upstream of or within cell migration involved in sprouting angiogenesis; positive regulation of angiogenesis; and regulation of gliogenesis. Predicted to be active in nuclear inner membrane; nucleoplasm; and rDNA heterochromatin. Is expressed in female organism; liver; male organism; and retina. Human ortholog(s) of this gene implicated in Huntington's disease and prostate cancer. Orthologous to human SIRT1 (sirtuin 1).

NR:

description
PREDICTED: NAD-dependent protein deacetylase sirtuin-1

GO:

id name namespace
GO:0002042 cell migration involved in sprouting angiogenesis biological_process

KEGG:

id description
K11411 SIRT1, SIR2L1; NAD+-dependent protein deacetylase sirtuin 1

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026939297.2 True 2582 mRNA 0.44 9 25365115 25386138

Neighbor

gene id symbol gene type direction distance location
LOC113541878 NA coding upstream 1098 25357389 ~ 25364017 (+)
tsnax tsnax,LOC107564242,LOC107557734,LOC107690806,LOC107730374 coding upstream 125946 25205139 ~ 25239169 (+)
gpatch11 gpatch11 coding upstream 173267 25183153 ~ 25191848 (+)
cacul1 cacul1 coding upstream 924660 24416490 ~ 24440455 (+)
ggps1 ggps1,LOC107728322 coding upstream 1019747 24316703 ~ 24345368 (+)
LOC113542106 NA coding downstream 64400 25450538 ~ 25459746 (+)
fbxo11a fbxo11a,LOC108263457,LOC108413220,LOC106590975,LOC107725019,LOC107679165 coding downstream 85337 25471475 ~ 25494533 (+)
kcnk12 LOC108430255,LOC107679129,LOC107688640,LOC107585442 coding downstream 129079 25515217 ~ 25538325 (+)
itga9 itga9,LOC107679186,LOC107688464,LOC107585444 coding downstream 211147 25597285 ~ 25672004 (+)
LOC117596833 NA coding downstream 290724 25676862 ~ 25685781 (+)
G52406 NA non-coding upstream 71844 25293033 ~ 25293271 (+)
LOC113542024 NA non-coding upstream 76528 25265631 ~ 25288587 (+)
G52363 NA non-coding upstream 109083 25255512 ~ 25256032 (+)
G52360 NA non-coding upstream 113853 25250975 ~ 25251262 (+)
G52359 NA non-coding upstream 114609 25250049 ~ 25250506 (+)
G52483 NA non-coding downstream 97665 25483803 ~ 25484191 (+)
G52683 NA non-coding downstream 502413 25888551 ~ 25888782 (+)
G52873 NA non-coding downstream 835175 26221313 ~ 26221544 (+)
G52858 NA non-coding downstream 870504 26256642 ~ 26344302 (+)
G52884 NA non-coding downstream 977301 26363439 ~ 26363733 (+)
b3galnt2 b3galnt2 other upstream 962661 24350184 ~ 24402454 (+)
LOC113540163 NA other upstream 1307217 24055154 ~ 24057898 (+)
slc29a3 slc29a3 other upstream 1530264 23793680 ~ 23834851 (+)
G51749 NA other upstream 1667821 23697032 ~ 23697294 (+)
G51562 NA other upstream 1909566 23454428 ~ 23455549 (+)
golga4 golga4 other downstream 176264 25562402 ~ 25594936 (+)
acoxl acoxl other downstream 415834 25801972 ~ 25846903 (+)
bcl2l11 bcl2l11 other downstream 464462 25850600 ~ 25864346 (+)
G53328 NA other downstream 1599840 26985978 ~ 26992711 (+)
znf451 znf451 other downstream 1811771 27197909 ~ 27207245 (+)

Expression


Co-expression Network