fgf8a (fgf8a,fgf8,LOC107673879,LOC107716294,LOC107696243,LOC108442712,LOC107585369)


Basic Information

Item Value
gene id fgf8a
gene name fgf8a,fgf8,LOC107673879,LOC107716294,LOC107696243,LOC108442712,LOC107585369
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047597.1
NCBI id CM018543.1
chromosome length 33776708
location 14898822 ~ 14904713 (+)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_034301895.1
TTAACCGCGGCTGTAAAGCGCGAACGGGGTTGACATTGGAGCCTGCATGGGAATGGGAGAAGAGGAGGGGATAAGAGAGGCTGCTCAGTACAGCAGCACCGTGTCCTGAAgagacatcatcatcatcatcatcattctcatcatcctcatcctcagcagcagcagtagtgcGGGATGCGTCGTCCTGATTCCACACACTGACACCCAAACGGAGTTGTGTCCACAGCAGGGACATCCGACTGGGACAAAACGTCAACGGAGTCCTCGCTGGAAATACACGCAGCCACCATTattttgctgtcattttttttaaatggacacCATGACTCAACTCGCTCTTATTTCAGTTAGTTTTACTTGAAAGATATCATTATAGATGCGTTTTGTGGTGTAACTTGGGAAGCTCATACTGCACGAActcgtggttttttttttttttttttttgcattaagtGCACTTAAGCCTTTCTTACTGAGCAGAAAATTGACCGCTGTCGGTTTGGGCTCGTCTCAAACCTACTTTTCAGCCTGCGCTGGTTGTCGTGTGCTGAGGCGTCCTTCATATTTCGGATTTTCCTCTCTGCTCCTGGGCAGATTGTACAGGCTACTGATCGCATCCTCGTCCTGTGAGCCATCCTTTGGATGTCCAAGAAGATCACCCTTTTCAGGGAGAGGACCTTGTCCATTTCCACTGGGAGACCCTGAGCTGTTATCTCTTCAAATCAGACGCTAATTTGGTCTACTAACTTTTATCTACGAGGTCAACAATGAGATTAATTCCGTCACGATTAAGTTATCTGTTCCTTCACCTCTTTGCATTTTGCTACTATGCTCAGGTAACCATTCAGTCCCCGCCTAATTTTACACAGCATGTGAATGAGCAGAGTAGGGTGACGGACCGGGTCAGCCGCAGACTCATCCGGACCTACCAGCTTTACAGCAGAACCAGTGGCAAGCATGTACAGGTCCTGGCCAACAAAAAAATCAACGCCATGGCCGAGGACGGAGACGTGCACGCAAAACTCATTGTGGAGACAGACACGTTCGGCAGTCGAGTTCGAATTAAAGGAGCTGAGACAGGATTCTACATCTGCATGAATAGGAGAGGAAAGTTGATTGGCAAgAGGAACGGTCAGGGGAAAGACTGCATTTTCACAGAGATAGTGCTGGAGAATAACTACACGGCTCTCCAGAATGTAAAGTATGAAGGCTGGTACATGGCATTTACACGCAAAGGAAGACCTCGCAAGGGCTCCAAAACCAGGCAACACCAGCGGGAAGTCCATTTCATGAAGCGAATGCCCAAAGGACACCACATTGCAGAGCACAGACCGTTTGATTTCATCAACTACCCTTTCAACAGACGGACTAAACGCACCCGTTACTCAGGAGAGCGCTGAAGAGTAATGCAGGAGAAAAGAGggggacagtgagtgagagtgagaaaataCCATCTCAGATAATGAACAGAATCCTCTTGTGGACtcctaaaatgatttttgtaCTGAGCATTAATATACCTAACatatagttttttaaataattttctagaaaagaaaaacacactctggaaaaaatacatggaaaaagttctatttttgtACTCCAGACTTTTAGTACTGACTTGTGTAAAAGTGTTAGGAAAGTGAAGCACATGGCTTGAGATACATGTGAGACATCAGAACTGACATTTTAGTAGTGTGTGGATTTCACCGTctcattgtttcattttgttttgtcagttttaGAGTAATTTATACTCTTCATATTGCTGCTCATGGGGACTTGGAGGGCCTGAGAGAAtgcactgacaaaaaaaaaaatgctgtattgAGTTACATGTACAGCCAAGGCACCTCTCGACCACCCAGTGATAAGACACCCAGCTCATCTGAGTAACCTCTGTGGCTCTTGGTTCTGGATTGTCCTTGAGATAAACAGTTAAAGCAAACACAGctttaaatacatatataattgtGGCAGCTACATTTTGATAATCAACACATTTCCTACCATGGTTTAACTGTTGAGGTGTTCAAGGTGTATAAATGCATTGTATGAAACGTAGGAAAGATGTTGTTCTTTGTGGcattgtgtctgtctgtttttatacatatataaatctatttttatttgaggatgtgtaaaataattttaatgatggaaatatttatttaaaaatgtgtaataaatttaCAT
>XM_034301900.1
ACTTTAACCGCGGCTGTAAAGCGCGAACGGGGTTGACATTGGAGCCTGCATGGGAATGGGAGAAGAGGAGGGGATAAGAGAGGCTGCTCAGTACAGCAGCACCGTGTCCTGAAgagacatcatcatcatcatcatcattctcatcatcctcatcctcagcagcagcagtagtgcGGGATGCGTCGTCCTGATTCCACACACTGACACCCAAACGGAGTTGTGTCCACAGCAGGGACATCCGACTGGGACAAAACGTCAACGGAGTCCTCGCTGGAAATACACGCAGCCACCATTattttgctgtcattttttttaaatggacacCATGACTCAACTCGCTCTTATTTCAGTTAGTTTTACTTGAAAGATATCATTATAGATGCGTTTTGTGGTGTAACTTGGGAAGCTCATACTGCACGAActcgtggttttttttttttttttttttgcattaagtGCACTTAAGCCTTTCTTACTGAGCAGAAAATTGACCGCTGTCGGTTTGGGCTCGTCTCAAACCTACTTTTCAGCCTGCGCTGGTTGTCGTGTGCTGAGGCGTCCTTCATATTTCGGATTTTCCTCTCTGCTCCTGGGCAGATTGTACAGGCTACTGATCGCATCCTCGTCCTGTGAGCCATCCTTTGGATGTCCAAGAAGATCACCCTTTTCAGGGAGAGGACCTTGTCCATTTCCACTGGGAGACCCTGAGCTGTTATCTCTTCAAATCAGACGCTAATTTGGTCTACTAACTTTTATCTACGAGGTCAACAATGAGATTAATTCCGTCACGATTAAGTTATCTGTTCCTTCACCTCTTTGCATTTTGCTACTATGCTCAGCATGTGAATGAGCAGAGTAGGGTGACGGACCGGGTCAGCCGCAGACTCATCCGGACCTACCAGCTTTACAGCAGAACCAGTGGCAAGCATGTACAGGTCCTGGCCAACAAAAAAATCAACGCCATGGCCGAGGACGGAGACGTGCACGCAAAACTCATTGTGGAGACAGACACGTTCGGCAGTCGAGTTCGAATTAAAGGAGCTGAGACAGGATTCTACATCTGCATGAATAGGAGAGGAAAGTTGATTGGCAAgAGGAACGGTCAGGGGAAAGACTGCATTTTCACAGAGATAGTGCTGGAGAATAACTACACGGCTCTCCAGAATGTAAAGTATGAAGGCTGGTACATGGCATTTACACGCAAAGGAAGACCTCGCAAGGGCTCCAAAACCAGGCAACACCAGCGGGAAGTCCATTTCATGAAGCGAATGCCCAAAGGACACCACATTGCAGAGCACAGACCGTTTGATTTCATCAACTACCCTTTCAACAGACGGACTAAACGCACCCGTTACTCAGGAGAGCGCTGAAGAGTAATGCAGGAGAAAAGAGggggacagtgagtgagagtgagaaaataCCATCTCAGATAATGAACAGAATCCTCTTGTGGACtcctaaaatgatttttgtaCTGAGCATTAATATACCTAACatatagttttttaaataattttctagaaaagaaaaacacactctggaaaaaatacatggaaaaagttctatttttgtACTCCAGACTTTTAGTACTGACTTGTGTAAAAGTGTTAGGAAAGTGAAGCACATGGCTTGAGATACATGTGAGACATCAGAACTGACATTTTAGTAGTGTGTGGATTTCACCGTctcattgtttcattttgttttgtcagttttaGAGTAATTTATACTCTTCATATTGCTGCTCATGGGGACTTGGAGGGCCTGAGAGAAtgcactgacaaaaaaaaaaatgctgtattgAGTTACATGTACAGCCAAGGCACCTCTCGACCACCCAGTGATAAGACACCCAGCTCATCTGAGTAACCTCTGTGGCTCTTGGTTCTGGATTGTCCTTGAGATAAACAGTTAAAGCAAACACAGctttaaatacatatataattgtGGCAGCTACATTTTGATAATCAACACATTTCCTACCATGGTTTAACTGTTGAGGTGTTCAAGGTGTATAAATGCATTGTATGAAACGTAGGAAAGATGTTGTTCTTTGTGGcattgtgtctgtctgtttttatacatatataaatctatttttatttgaggatgtgtaaaataattttaatgatggaaatatttatttaaaaatgtgtaataaatttaCAT

Function

symbol description
fgf8a Predicted to enable growth factor activity; type 1 fibroblast growth factor receptor binding activity; and type 2 fibroblast growth factor receptor binding activity. Involved in positive regulation of somitomeric trunk muscle development. Acts upstream of or within several processes, including animal organ development; determination of bilateral symmetry; and nervous system development. Located in extracellular space and lysosome. Is expressed in several structures, including germ ring; head; mesoderm; nervous system; and neural keel. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 6 with or without anosmia and prostate carcinoma in situ. Orthologous to human FGF8 (fibroblast growth factor 8).
fgf8 Enables growth factor activity; type 1 fibroblast growth factor receptor binding activity; and type 2 fibroblast growth factor receptor binding activity. Involved in several processes, including animal organ development; dopaminergic neuron differentiation; and negative regulation of cardiac muscle tissue development. Acts upstream of or within fibroblast growth factor receptor signaling pathway. Located in extracellular space. Implicated in hypogonadotropic hypogonadism 6 with or without anosmia and prostate carcinoma in situ. Biomarker of breast cancer; choriocarcinoma; embryonal carcinoma; endodermal sinus tumor; and prostatic hypertrophy.

NR:

description
PREDICTED: fibroblast growth factor 8-like isoform X1

GO:

id name namespace
GO:0021555 midbrain-hindbrain boundary morphogenesis biological_process
GO:0046850 regulation of bone remodeling biological_process
GO:0001756 somitogenesis biological_process
GO:0021571 rhombomere 5 development biological_process
GO:0021572 rhombomere 6 development biological_process
GO:0021588 cerebellum formation biological_process
GO:0055011 atrial cardiac muscle cell differentiation biological_process
GO:0055012 ventricular cardiac muscle cell differentiation biological_process
GO:0030177 positive regulation of Wnt signaling pathway biological_process
GO:0061195 taste bud formation biological_process
GO:0009880 embryonic pattern specification biological_process
GO:0043049 otic placode formation biological_process
GO:0051216 cartilage development biological_process
GO:0035050 embryonic heart tube development biological_process
GO:0048263 determination of dorsal identity biological_process
GO:0003208 cardiac ventricle morphogenesis biological_process
GO:0008543 fibroblast growth factor receptor signaling pathway biological_process
GO:0031076 embryonic camera-type eye development biological_process
GO:0070121 Kupffer's vesicle development biological_process
GO:0007368 determination of left/right symmetry biological_process
GO:0048339 paraxial mesoderm development biological_process
GO:0021703 locus ceruleus development biological_process
GO:0048665 neuron fate specification biological_process
GO:0060271 cilium assembly biological_process
GO:0010002 cardioblast differentiation biological_process
GO:0030878 thyroid gland development biological_process
GO:0007422 peripheral nervous system development biological_process
GO:0030901 midbrain development biological_process
GO:0060037 pharyngeal system development biological_process
GO:0030903 notochord development biological_process
GO:0030335 positive regulation of cell migration biological_process
GO:0048705 skeletal system morphogenesis biological_process
GO:0042664 negative regulation of endodermal cell fate specification biological_process
GO:0048709 oligodendrocyte differentiation biological_process
GO:0060059 embryonic retina morphogenesis in camera-type eye biological_process
GO:0005764 lysosome cellular_component
GO:0005615 extracellular space cellular_component
GO:0005104 fibroblast growth factor receptor binding molecular_function
GO:0008083 growth factor activity molecular_function

KEGG:

id description
K04358 FGF; fibroblast growth factor

RNA

RNA id representative length rna type GC content exon number start site end site
XM_034301895.1 True 2199 mRNA 0.43 5 14898825 14904713
XM_034301900.1 False 2169 mRNA 0.43 5 14898822 14904713

Neighbor

gene id symbol gene type direction distance location
slc2a15a slc2a15a,LOC108262874,LOC103035008,LOC108442702,LOC107716293,LOC107673883,LOC107708408,LOC107696166,LOC107585370 coding upstream 27723 14857929 ~ 14871099 (+)
b3gat2 b3gat2,LOC107718837,LOC107694338,LOC107588666 coding upstream 225823 14658756 ~ 14672999 (+)
asrgl1 asrgl1,LOC105911569,LOC103032358,LOC108442615,LOC107695955,LOC107585330,LOC107673965 coding upstream 286852 14595202 ~ 14611970 (+)
eef1a1a LOC108263602,LOC108441988,LOC108442579,LOC108258313,LOC107704332,LOC107602754 coding upstream 547587 14346597 ~ 14351235 (+)
slc17a5 slc17a5,LOC107673875,LOC107585335,LOC107693696,LOC107588676 coding upstream 557534 14331492 ~ 14341288 (+)
fbxw4 fbxw4,LOC107707737,LOC107716323 coding downstream 6186 14910899 ~ 14936204 (+)
wbp1la wbp1l coding downstream 42120 14946833 ~ 14961193 (+)
cnnm2a cnnm2,cnnm2a,LOC107585325,LOC107716327,LOC107673921,LOC107588659 coding downstream 73012 14977725 ~ 14994070 (+)
polr1c polr1c,rpac1 coding downstream 120211 15024924 ~ 15029815 (+)
ldb1a ldb1,ldb1a,LOC108442788,LOC108444470,LOC107707596 coding downstream 129350 15034063 ~ 15058779 (+)
LOC113541837 NA non-coding upstream 272332 14617608 ~ 14626490 (+)
G46337 NA non-coding upstream 510511 14388029 ~ 14388311 (+)
G46217 NA non-coding upstream 610535 14286650 ~ 14288287 (+)
G46176 NA non-coding upstream 715176 14183437 ~ 14183646 (+)
G46175 NA non-coding upstream 715629 14182991 ~ 14183193 (+)
G46638 NA non-coding downstream 61193 14965906 ~ 15011989 (+)
G46713 NA non-coding downstream 109410 15014123 ~ 15015181 (+)
G46765 hps6 non-coding downstream 175100 15079813 ~ 15084310 (+)
G46833 NA non-coding downstream 514316 15419029 ~ 15419642 (+)
G46849 NA non-coding downstream 568488 15473201 ~ 15473870 (+)
cgas NA other upstream 530722 14361367 ~ 14368100 (+)
slc24a3 slc24a3,LOC107693448,LOC107718828,LOC107716313,LOC107673935 other upstream 612280 14213369 ~ 14286542 (+)
pcbd1 pcbd1,LOC107743500,LOC107601888,LOC107655445,LOC107559335 other upstream 1397772 13498048 ~ 13501050 (+)
si:ch211-223p8.8 si:ch211-223p8.8,LOC108262662,LOC108426807,LOC107552909,LOC107743613,LOC107552922 other upstream 1864472 13032050 ~ 13034350 (+)
col17a1b LOC108263226,LOC108426809 other upstream 1893499 12982406 ~ 13005323 (+)
borcs7 borcs7 other downstream 67855 14972568 ~ 14974068 (+)
eif4ebp2 eif4ebp2,LOC107564345,LOC107668794,LOC107716353 other downstream 888693 15793406 ~ 15797204 (+)
cxcl18a.1 LOC108263637 other downstream 1166001 16070714 ~ 16075650 (+)
cxcl12a cxcl12 other downstream 1219914 16124627 ~ 16134002 (+)
lrrc18a lrrc18,LOC108263378 other downstream 1329801 16234514 ~ 16237542 (+)

Expression


Co-expression Network