egr2a (egr2a,LOC108269483)


Basic Information

Item Value
gene id egr2a
gene name egr2a,LOC108269483
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047604.1
NCBI id CM018550.1
chromosome length 29376037
location 15906357 ~ 15914710 (-)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_034308030.1
ATGGGCAATACCTATCATGCTTTGGGAGTGTGGTCATCCATCTTCCTGGGCTCTCCACCCACACACTGGGTAGAAGGGGTGAGAATTAACAACATACCAGCGAGCAGTGCCTCATATTTAACATATCCAATAAACAGAGATATCCGTTGTAATCATTTCTATATCCTCAATTATAATGCCTGGTTAAACCCGAACTTCAAAACTCAGTGCTTTTGGGCAACTTTGCAGTGGCTTAAAATGACAGCTAACAGTGTGGATAAAGTCGCTGAGTCGCTAACTGATTTCATACGCTCCATTGCAACGGATGCTTGTCCTATGGATGAAATCCCTACAGACTTACCGAGCGGCTTTCCTCATGTAGACCTGGGAAGCGAGGCATCAGGAGGTGGCCTGGGCGCGGACAGTTTCTCTAAGGAAAAGCGCACTGCTGACTTTATAGACCCGAATAACACGCAGAGCTCTCCTGTCGCCTACACGGGCAAGATTTCCATCGGCGCTCAGTGCGCACACGGCAGCTGGAACGCAGACAGCCTGATAAACTTTGTCTGCGCAGAGGTACAAAGCGCGACACCTGCCCTCACCCCTTTCCCTACCTCCTCTCCAGGACCCACAGACCTCTCAGGGGCTCCAGCTTGTCCCAAAGGCCACGAGAAGGATATGGAGCACATGTACACATCACCTCCACCTTACACCTGTAGTGCGGACGGCTACCAGGACCCCTCGACCTACCTATCAACCAGTACATGTCCGATCACGTACCCGCCAGCTTCTTACACATCCCCGAAGTCCACCATAGACGGTGCGCTTTTCTCCATCATACCAGATTACGGGGGTTTTTACCAGAGCAGCAGCCAAAGGGATGCGCCAGTCTTCCAGGACCGAAAACCGTTTTCCTGCTCTCTGGACACCGTTAGAGTTCCTCCGCCCCTCACTCCGCTGAACATGATAAGAAATTTTACTCTTTCGTGTCCCATGGACGGATTGAGGCCGCCCACGGACTCCAACCCTCAGAGTGTCCCGTTACGACCAATACTGCGACCGAGGAAGTACCCGACCCGGCCGTGTAAGACCCCGGTGCATGAGCGGCCGTACCCGTGTCCAGCGGAGGGCTGCGACCGCAGGTTCTCGCGCTCCGACGAGCTCACGCGCCACGTGCGCATCCACACCGGCCACAAGCCGTTTCAGTGCCGCATCTGCATGCGCAGCTTCAGCCGCAGCGACCACCTAACCACCCACATCCGCACGCACACGGGCGAGAAGCCCTTCTCCTGCGACTTCTGCGGCCGGAAGTTCGCCCGGAGCGACGAGCGAAGGAGGCACACGAAAATTCaccaaagacagagagagaaaagggcgAGCGCTCCTCCTGCCCACACATCAGGCGCTCAGGGCTCCATGTGAGAAAGAAACGGCCTCCTGAACCCTGACCACGTGATAAGGAAAGGGCGCTGGACAGAGGACCTTGTTTACCACCTTTCAGCTCGAGACGCCATATTGTTTAAATGGGTACGTCCTAAACTGTGTACTACCTTACTTAACCAGGACATGCAGAGTTCTTCAGGGGGACGagctcagatttaaaaaaaaaaaaaaaaaacggaatcCACACGTTCCCAGCCCTGGTCTTGGAGTACCCCTGTCCTTGCGCATTTTGATgtctttgctgctgtaacacatcTGATTCAACTTATCAATATTGTACAATAttgagttgaagtgggtgtgttagagcagggaaaacactaaaatgttcaGGACAGGGCTAGTCCAGGACCCTTATCATGGGCAGAGTGCTCGCTGCAGTGGAAAGACTGACCTGGAGTCAGGGTCCCTGGAAAATGGGTCCTCAAAGGGTCTAATGTTAGCATTTTCAACAGGTAGATGAGGTTGCCCACAGAGACTGCATTTGCACAGGGCCTAGAAATGTAGAATACtgaatgtaaacaaacacattctTAACtggatatattttttacatttttatttcaatgtgtaataaatatgaaagtGGCTTGCCTTGCAGCCTCTATCTCAGTCCTACTTTCAGTAGGACAAACATTTAGCCCCATAGCTGCCTCCTTTCTCACTCACTATGGAATATTGAGTAAATTTGCTACTGAATCATGTTCCAAACAGCAACATTGAAGTTTGTTTTCCAACTTAGCTGTTAAACCTCTATTCAGTGTATATGGCATTTTTTTCAGTAGAAATTGTTTAAATCTTCTTCAAGAAGGTAAGGTACGAAGCTGAACTGAAATACAGAGTAAAACAATAATGTTTTCTTAGCAGCTGGGAGCTAACTAACTGATAAACATTAGAGTTCCAAGGTTAAACCTACATATGCTGGTTGGAAATAATCACGTACATGTTCAACTGATTTAGACGTATTAACAaagttctgtgattttttttttttatctatacCTACTTTAgcttactatttattttttcctcttacttTACCTATAACTTTTATACAGCAGGTTAGTTATTTAGGAagaaaatgcagatttttttttaattgtctgctgctttttttcctcaagcCATTTTGCTCATGTCATTGTTGTAATTCATACTTTGCCTAAAAACATGTCTGTAATTTATACTGAAATGGGGCACTTCTGCTTTAAAGGGAGCTCTGAAAGAAGTGCCCCACCCTCTGCATGTGCCTGGTAATAAGTGGTATATAAAAACAGTATGATATTGCACGGTACTATGAGATTTCTGACCTGGCCTGTGTGTGCAAATCAAAGGCAGCTTTATATGAGCCTTGTGTATGACACTGTTTATGTATTTCACATGATCAGGGGGGAAAACCCTGCTGTTACAAATACCCTGTTTGGGCTCTGTATATTCTGTTTCTTGAAAGTCTAGGTCtgctgtttaaatgtttgtaacTGATGATTTCCTTTGTAACATTCACAGATCACTGTATAGAATTAACCGCTGCTTTTCGTAACTGGTGAAGTAACGCTCACTTTACTATCTTACTGTGATTTTTATGCTGACTTTTTGTGAAACTGGGCCCTTCTCAAGAACTGAATTTGTTCCTAGTGTGCCCTAATAACATTTGTTCTGTATACAAAAGAAGTGTGTCCAAATCATGTTATAAGGTGTTAATCTGtgaatgatttaattaatacaatGTAGATATGCTTTACATGCAGTGTTGCAAGTGGGCAAGTTTAAAGTGCCAGGCATTACATAGTCATACCACTAGAGGCTACCCTTTGACATCTTTGGGTAAGACAGGAAGGTAAGGTGTAAGTGAACCCAGGATCCCACTTACACCCGGACATTTCATAAGTCTTGTATACTTTGTTTCCTGCTAAGATTTTAACCACATGCACTTACACTTGTAGACAAATGCATCTCTGGTCAGACTGAAATCTGCATTTATGagttaatatgcaaattacattCGAACACCAATTTGCACTGTTTCTCATTTTTAGTTAGTTTTATTTGAAAGTTGCCACATCAGgatttttcataaccttttaAATCTTACTAGTTTTAATGGCACCAATATTAACAAGTGCATCAAATTCATTTATACCTGTACTGTATAACATGGCTGCATTCATTAGTGGTTTGGATGATcagatttaaatgtttaaaatgtatcttttgGGTGAATTTACACTTTCATTATTATGTGTATAATCTGGATGTAATCCTGATACTCAGGACACATGAACCAAAGTGTAAATGGAATCTAGAATacttg

Function

symbol description
egr2a Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in hindbrain and hindbrain neural keel. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 1D; Charcot-Marie-Tooth disease type 3; Charcot-Marie-Tooth disease type 4E; and motor peripheral neuropathy. Orthologous to human EGR2 (early growth response 2).

NR:

description
PREDICTED: early growth response protein 2b-like

GO:

id name namespace
GO:0048168 regulation of neuronal synaptic plasticity biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0071320 cellular response to cAMP biological_process
GO:0071371 cellular response to gonadotropin stimulus biological_process
GO:0043066 negative regulation of apoptotic process biological_process
GO:0042552 myelination biological_process
GO:0035914 skeletal muscle cell differentiation biological_process
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0046872 metal ion binding molecular_function
GO:0003676 nucleic acid binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function

KEGG:

id description
K09203 EGR1; early growth response protein 1

RNA

RNA id representative length rna type GC content exon number start site end site
XM_034308030.1 True 3733 mRNA 0.44 3 15906357 15914710

Neighbor

gene id symbol gene type direction distance location
rtkn2a LOC108269925 coding downstream 16819 15883398 ~ 15889538 (-)
zfyve28 zfyve28 coding downstream 28013 15864120 ~ 15878344 (-)
nt5c1ab LOC108269929,LOC108425685,LOC106610886 coding downstream 42729 15858730 ~ 15863628 (-)
si:dkey-21a6.5 NA coding downstream 51174 15848037 ~ 15855183 (-)
mrpl35 mrpl35 coding downstream 58982 15843470 ~ 15847375 (-)
jmjd1ca LOC108270245 coding upstream 3091 15917801 ~ 15981784 (-)
ahsa1b ahsa1,LOC108425677,LOC107732084 coding upstream 72376 15987086 ~ 15992896 (-)
si:dkey-229e3.2 LOC108269466 coding upstream 86352 16001062 ~ 16007423 (-)
eprs1 eprs,LOC107732550 coding upstream 95767 16010477 ~ 16035433 (-)
LOC113539022 NA coding upstream 101642 16016352 ~ 16016484 (-)
G166319 NA non-coding downstream 9787 15895667 ~ 15896570 (-)
G166289 NA non-coding downstream 60102 15664486 ~ 15846255 (-)
G166286 NA non-coding downstream 298835 15605903 ~ 15607522 (-)
LOC113539013 NA non-coding downstream 415349 15481130 ~ 15491008 (-)
G165951 NA non-coding downstream 660448 15245584 ~ 15245909 (-)
G166380 NA non-coding upstream 18447 15933157 ~ 15933437 (-)
G166390 NA non-coding upstream 85509 16000219 ~ 16000512 (-)
G166484 NA non-coding upstream 352519 16267229 ~ 16267515 (-)
G166633 NA non-coding upstream 530131 16444841 ~ 16446005 (-)
G166865 NA non-coding upstream 829896 16744606 ~ 16744822 (-)
eml5 eml5,LOC108435760 other downstream 143639 15715560 ~ 15762718 (-)
ktn1 ktn1,LOC107668535 other downstream 242862 15633002 ~ 15663495 (-)
pgfb pgf,LOC108435746 other downstream 584306 15303235 ~ 15322051 (-)
capn3a capn3,LOC108269768,LOC108435782 other downstream 788993 15107120 ~ 15117364 (-)
nenf nenf other downstream 824152 15079696 ~ 15082205 (-)
mideasb elmsan1 other upstream 958569 16873279 ~ 16898730 (-)
htr1b htr1e,LOC108269541 other upstream 1252158 17166868 ~ 17247823 (-)
cmpk2 cmpk2 other upstream 1701028 17615738 ~ 17624534 (-)
G167566 apob other upstream 2391033 18305743 ~ 18316207 (-)
gdf7 LOC108270114 other upstream 2460693 18375403 ~ 18382455 (-)

Expression


Co-expression Network