aurkb (aurkb,plk4,LOC108431899,LOC107704466,LOC107712916,LOC107705065,LOC105908766)


Basic Information

Item Value
gene id aurkb
gene name aurkb,plk4,LOC108431899,LOC107704466,LOC107712916,LOC107705065,LOC105908766
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047607.1
NCBI id CM018553.1
chromosome length 26458119
location 20414100 ~ 20418381 (-)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026916159.2
CTCACGGCGAGGAAGTACCTCAGCCAATCACGGACAGGAGGATGTGGCGTTGTTCGTTTTGAAAACGTTGGCGGTTTGTCCAGGAAAGAAGAGAGCGACGAGTGCTGCTGCTAAACCAATAAAAGAAATTGAGATtttaaagctgatttttttgtaatacGTTTTGGAGACATGCAGAACAAGGAGAACCGTGAACCCAGAAGCCTCCTCACACAGACGGTCGGACCTCTCAGAGAAGAGATGAACCCTGGTGCTGTCATGGGCACTGGTCCTGGCCGAGTCCCGGTGAAACCCAGCACACAGAAGAAGTTCTCAATTAAGGACTTTGATATTGGTCGGCCGCTGGGAAAAGGAAAGTTTGGGAATGTGTATTTGGCGCGAGAAAAGAAGCTGAAGACCATCGTGGCACTGAAGGTGCTCTTTAAATCCCAGATGGAAAAGGAAGGAGTGGAACACCAGCTCAGGAGAGAGATTGAAATCCAGTCTCACCTCAGGCATCCGAACATCCTGCGCTTCTATAACTACTTCCACGATTCGTCGCGTGTGTTCCTCATTCTGGAGTATGCACCACGTGGAGAGATGTACAAAGAGCTGCAGCGTTGTGGCCGCTTCAGTGATCAGCGCACAGCCACGtttaTGGAGGAGGTTGCAGACGCTCTTCAGTACTGCCATGAGAAGAAAGTGATCCATCGCGATATTAAACCTGAGAATCTGCTCCTGGGCTTCAGAGGAGAGCTCAAAATTGCGGACTTCGGCTGGTCTGTCCATGCGCCGTCGCTACGgcgaCGCACCATGTGTGGCACTCTGGATTATCTTCCTCCTGAGATGATTGAAGGGCATTCTCATGATGAGAAGGTGGATCTGTGGTGCATCGGTGTGCTGTGTTACGAGTGTTTGGTGGGAAATCCTCCATTCGAGACAGCCAGCCATTCAGAAACATACAAACGCATCACCAAGGTGGATCTACAGTTTCCCAAAGTGGTTTCAGACGGCGCCCGTGATCTGATCTCCAAGCTGCTGAGACACAGCCCCTCCATGCGTCTGCCTCTAAAGAGCGTTATGGAGCACCCATGGGTGAAGGCCAACTCGCGCAGAGTCCTGCCCCCTGTCTGTCAGCCCAAACCCACTCCTTCACACTAGCCTAAATTCCTACTCAGtgcttttaatctttttaataaaaaaaatatttaatgagta

Function

symbol description
aurkb Predicted to enable histone serine kinase activity. Acts upstream of or within chromosome segregation; cytoskeleton-dependent cytokinesis; and microtubule cytoskeleton organization. Predicted to be located in midbody and nucleus. Predicted to be part of chromosome passenger complex. Predicted to be active in spindle microtubule; spindle midzone; and spindle pole centrosome. Is expressed in several structures, including blastomere; midbrain hindbrain boundary; nervous system; and proliferative region. Human ortholog(s) of this gene implicated in spermatogenic failure 5. Orthologous to human AURKB (aurora kinase B) and AURKC (aurora kinase C).
plk4 Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within centriole assembly; cilium assembly; and developmental growth. Predicted to be located in centriole; deuterosome; and nucleolus. Predicted to be active in cytoplasm; microtubule cytoskeleton; and nucleus. Is expressed in brain; eye; nervous system; and pronephros. Used to study ciliopathy. Human ortholog(s) of this gene implicated in microcephaly and chorioretinopathy 2. Orthologous to human PLK4 (polo like kinase 4).

NR:

description
PREDICTED: F-box/LRR-repeat protein 12

GO:

id name namespace
GO:0036089 cleavage furrow formation biological_process
GO:0034501 protein localization to kinetochore biological_process
GO:0007275 multicellular organism development biological_process
GO:0000122 negative regulation of transcription by RNA polymerase II biological_process
GO:0051256 mitotic spindle midzone assembly biological_process
GO:0002903 negative regulation of B cell apoptotic process biological_process
GO:0007059 chromosome segregation biological_process
GO:0043988 histone H3-S28 phosphorylation biological_process
GO:0032467 positive regulation of cytokinesis biological_process
GO:0034644 cellular response to UV biological_process
GO:0000281 mitotic cytokinesis biological_process
GO:0005634 nucleus cellular_component
GO:0005694 chromosome cellular_component
GO:0005524 ATP binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0035174 histone serine kinase activity molecular_function

KEGG:

id description
K11479 AURKB; aurora kinase B

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026916159.2 True 1197 mRNA 0.50 9 20414100 20418381

Neighbor

gene id symbol gene type direction distance location
trnal-aag_9 NA coding downstream 1170 20412849 ~ 20412930 (-)
bod1l1 bod1l1,LOC107705061 coding downstream 1972 20400480 ~ 20412128 (-)
LOC117598840 bod1l1 coding downstream 13625 20394684 ~ 20400475 (-)
nkx3-2 nkx3-2 coding downstream 27475 20383757 ~ 20386625 (-)
rab28 rab28,LOC102780097,LOC106600633,LOC107712918 coding downstream 39524 20342473 ~ 20374576 (-)
tmem107 tmem107,LOC108274527 coding upstream 1377 20419758 ~ 20424672 (-)
LOC113528321 fbxl12 coding upstream 8378 20426759 ~ 20430515 (-)
LOC113528637 fat4,LOC107717300,LOC107694441 coding upstream 189243 20607624 ~ 20697160 (-)
spata5 spata5 coding upstream 486143 20904524 ~ 21003477 (-)
LOC113528290 LOC108273900 coding upstream 663638 21082019 ~ 21143863 (-)
G214159 NA non-coding downstream 357956 20020552 ~ 20056144 (-)
G213879 NA non-coding downstream 750338 19663337 ~ 19663762 (-)
G213716 tnrc6a non-coding downstream 991685 19417184 ~ 19422415 (-)
G213549 NA non-coding downstream 1341115 19023758 ~ 19072985 (-)
G213407 NA non-coding downstream 1564953 18792435 ~ 18849147 (-)
G214325 NA non-coding upstream 17671 20436052 ~ 20438834 (-)
G214331 NA non-coding upstream 27142 20445523 ~ 20445748 (-)
G214493 NA non-coding upstream 360384 20778765 ~ 20781702 (-)
G214526 NA non-coding upstream 423050 20841431 ~ 20841634 (-)
G214626 NA non-coding upstream 484717 20903098 ~ 20903837 (-)
hs3st1 hs3st1 other downstream 200471 20205339 ~ 20213629 (-)
slc2a9l2 slc2a9 other downstream 275887 20039787 ~ 20138213 (-)
lyar lyar other downstream 429951 19940354 ~ 19984149 (-)
rbbp6 rbbp6 other downstream 965541 19429217 ~ 19448559 (-)
si:dkey-204f11.64 LOC108274053 other downstream 1586366 18823471 ~ 18827734 (-)
spry1 spry1 other upstream 481676 20900057 ~ 20905271 (-)
fgf2 fgf2,LOC107717315 other upstream 596058 21014439 ~ 21028081 (-)
slc16a2 LOC108279893,LOC107596364 other upstream 818421 21236802 ~ 21272507 (-)
LOC113528016 thegl other upstream 933900 21352281 ~ 21359190 (-)
G215187 NA other upstream 1257890 21676271 ~ 22269092 (-)

Expression


Co-expression Network