rest (rest)


Basic Information

Item Value
gene id rest
gene name rest
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047607.1
NCBI id CM018553.1
chromosome length 26458119
location 21620631 ~ 21631906 (+)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_034309812.1
GAGTGTACCTATCTAGGGAGTCTGCAGGCGTTTGGGACTCCGCCACGCAGCGCTGTGTTGGAATGCGTCGAGACTCGTACTTCCCTGAACAAGTTTAGCTGAAAAGTTAGTTTTGAGAGAGTCTAAAACTTCGAAGAAGCTTCTCGAAAATATCGACAGACGTCGAACGAAAGTGCAGGCTGATCGAGCATGGCCTCTCAGACAGCATTTAATCTCTGCACGGACGTCTTTGTGACCTCTAGAAGTGCTTCACTGCCCGAAGAACCTGAAGTAAGTGCAATTTCTGGTACAGAGCTTCCTGCGCCTCAGCTTGTGATGCTGGCCAACGTGGCCCTAAACACAGAGTCGCCGCCAGAGGAGGAGAAGCAGATGGCAGAACTGAAAAACGTCGGATGCTGTGGCTACTCGGACAGCGAGGACGAGAACGTGGTCCACTACAGCTACGATGAGACAGCAGAAAATGTGGACGAAGGGACCGGGATGGGAGAAAACAGAGTAGAAAAAGTCATCGAAACTGCTGAGACGGTGCCAACCGACCTTTCAAAGAAATCTCCTGAAACCGAACCTTCTGCAAAACCTAAACAAGGTTCTGTTGCTGTGCCAAATGTGGCAACAGAACctgcaaagaaaaagaaaaagccattCTACTGCAAGCCGTGCCACTTTCAAGCTGAGTGTGAAGAGGAATTCGTACAGCACATCCGTGTCCACAGCGCTAAAAAACTGATTGCTGAAAAGGCAGGGAGTGTAAATTCGGATGACGAATCGAATCAGGCACAGCAAAAATCTGCAGAAAACTGTGTCAAGGGCGTGATCCGCTGTGAGCGCTGCGGCTACAACACCAACCGTTACGACCACTATGTAGCACATCTGAGGCACCACAAGAACGAAGGGGACGAGCAGCGAGTGTTCAGGTGCACCATCTGCCCATACTCCACCGTCAGCCAGTATCACTGGAAGAAGCACCTGAGGAACCATTTTCCCAGCAAGCTGTTCACATGCGGCCAGTGCAGCTACTTCTCTGACAGGAAGAACAACTACATCCAGCACATTCGCACACACACCGGTGAGCGTCCTTTCCAGTGTGTTTACTGTGACTACTCAAGCTCTCAGAAGACCCATCTCACGCGGCACATGAGAACACACTCTGGTGAGCGACCGTTCAAGTGCGACAGCTGCAGCTATTTGGCAGCCAATCAACACGAGGTGACACGTCATGCCAGGCAGGTGCATAACGGACCCAAGCCGCTCAGCTGTCCTTACTGCCAGTACAAAACAGCCGATCGCAGCAACTTCAAAAAGCATGTGGAGCTGCATGTCAATCCAAGGCAGTTTCTTTGCCCCGTCTGCAAGTATGCTGCATCCAAGAAATGCAACCTGCAGTACCACATCAAGTCCAGGCACCCGGGATGCTCAGATATCTCCATGGACGTGTCCAAGGTCAGGCTGAGGGTGAAGAAGGCAGACGGGGATGATTTGAAGCCAGTTTCAGAACCAAGGACAAGGGATAGACGAAAAGCAGAGGTGTCCGAGGATGCCGATTCAATCGTAGGCCCCATCAACCTCTCCATTAAAAAGAGTGGAAAGACGAATTTGGATGGTGAGAGTGCCAAAAAACCCGCTTCCGAACCCACAAAAGAAAAATCGTGTGAGAAGAGAGCAGAGAAAAGAGCTGCACCaagaaatgaaggaaaagaaacaagCAGCAAGAAAGCGAGAATCAAAGAAACTGTCCCCTGTGTCGAGAAacaagatggaaagaaagacaaGGAGGTGAAAAACGCAGAGAAAGTTGCTAAATCTTCAGACAGAGTCACTAAAAGTCGAgctaaaaaagaagaaaaggctGCAAAGGAAACGAAAGAGACACTCACCAAAAATCATGATGGTTCTGAAGAGGAAAACAGAACAGATCTTGAGAAGAGGCAGCAGACTCAAAGGATGGAGAAAGAAATGAGGGCAAAGGAGcagaagcagagagaggaggaggaaaggagagaaagaaagaggcagGAAGATGAAAGTCTGGAGagaatgaagaaagagaaagaacataagcagagggaggaggaggaaaagagaacGGCAAGAGAGCgacaggagaaagaaagaaaagagaaaaaggaggaggaaCAGAGGGAAAGGGAAAGGctggagagagaaatgagagcgaaagaggaggaggaaagaagagaaagtgagagagtagagagagaaatgagtgaGAAGGAGCTGAagcagaaggaggaggaggaacggagagaaagagagaggctggagaAGGAAAGCAAACTTCAGAAATATGATGTACAGAAAAGAGAGGTGGAAAATGTTAAAGGTTCCAAAATGGCCAGGAAAGCAACCAAGAAACATACAGGAACAGTGAATTGTGATATGGAGAAGTCTCAGAATTGCGAGAAAGCCGAGACGAAAACGGTGAAACGCAAAAAAGCAGAGTGTGCACCTTCTCCTCAGGCAGAGAAAGCCAAACGCAGGAAGGCGAAGGTTACAAACAGCCCATGCACAAGCATGAGCACACCTGGAGAAGTGAAGAGGTCAAAGGGCAGTGGCAGgcaaaacagaaagacaaacaagcTGGAGGTTAGTGTTAAGGTTAAGGCAGCAAAAGCTCTGGAATGTTCCTCCAAGCCTGAAAAAGTGCAATCTGGCCCAATAAAAGATCAAATTTCAACAGAGAAAGTGTCTCACACTTCTGAGGAGCTGAGCATAACAAAAAATCTATCGGAGAAGCCGTCTTCAGAAGACAAAGTCACAAGAGTGAAGGCCACCACTGAAGGAAAGGGCACCGCGGAAGCACAGACATCTTCAGATATTGATAGTGGGACGGATAGTCCAACACTGGACTTGTCCAAACCTCCGTGTAGCAAATCTCAGGACGGTGAAGACGACGAGGGCATCCACAGCCACGACGGAGGAAGTGACATCAGCGACTGTGCCTCGGAGGTAAGTTACGACTCCGGGCTCAACGGGAAGCTTCCGGAAACACCGACTGAAGAACTTCCGTCACCCACGCAACTGCTCAGCCACACATGCGTGTTCTGTGACCGCACGTTCCCTCTGGAGATGGACTACAGGCGGCATCTCAATCGCCATCTGGTTAATGTCTATTACCTGGACACTGCGACACAGGGGAACAAGTAGACTTCATTTCTACTTAAGGTTTTCAGTCATCTGGGTCATTTAAAAGTGTCCAGCAGTAACCATAATTCAAGGCAGCTGGACTTGGactatcatttaaaaaaaggccGCCTTGACTCTAGTCACCTTGACGTAAGGTCTCAGCATTCTTTTTGCAGAGACAACAGTTGGAAGATTTAGCATACACCGTGCTTAGGAGGCACTCTTCACCATTTaatcatcattttgtcatttacagctctctgtgagctttttgggtgtggctaaatgtcAATCAGCTGTGCCATAAATGCGGTTGGTCATTTCTGGaagattggcatttatcaaaaTGTGCACcagaatatgaagaaaatcagcgttaaCTGAGCTTTTGTAAATCTgcctggaatttttttttgttcagtttggccTATGAAGATATTTGCACacaacgtttttttttaaagacggATAACTGAGGCCTGTTGTTAGCACTCCTGAAGAAAGCAGCCTAGTTGTCAGAAATTCTGGGCAGCCTTTATTTAAGGGTAACTGTCTTGTATGGTTGCTTGTTTTGGacaaatttgaagaaaaaaatgctgcGTGTATCCCTCTCAGAAGGTAATTGCATAATTCCATTTATCAGACAAAAGTTCTGTGAATGTTCTCAGAACTGTTacacaaaatcatgataatATTGCAAACTGTGATATCAGCGCATGTCTGATAATTATCTTATTATGTAATCCTATGGGAATTAATCGTAATATGTAGAAACAAGCAAGTGTTACTTTGTACATTGACTTTCATCTTAAAAGTTATCTTAGAGCACTCGAGTGGAGATTCTGAATATTCTGTTCTTTTTCAGCTTCATAATTCGGTCCAAAGATTGTTTAAGACTGTTTATGACTGTCTCCCGCTCTTGTTTCCTTAAAAGAaaagtttggccaaaaatgaaatgcacacaTTGTTCCCCTTGGACTGTATACCGTAAGCTTCTTTTATTTGTTAGCAATGTGAACTTCGTAGCTCAAGTGCAAAGCTAAACAAGCAAACTACATATGGGGTAGGGAGAAAAACGTTGAGCTTTACACTGTATATGTCACTccagttgttgtttttccttttttttttaatgcttctgacaatcgtttttttttttcccctttggtaattttgtactttttgttgTTAGTTTGACTTTCTCTTTCCTGCTTTCTCTGCTAATTGTCATCAAACTGAATTATGATTCTAACCTTGTGCCACTGATCTGATGTGTGTGGAATAGAACCATGCTTGATTTTCATGGCCATCTAAATCAACATgtctgtctttaaaaaaaaaaaaaaaaaaactagattttttattattattatttttattaagtgcAATATTATATATTGGGTATACCAAAGTGGAAAAATTCCCCTGCCCTGCATCTAACTCtcttttgtaaaaaataaaacttcgATTAGATGGATAGATTAGAATTACTATTACTATAAATGTTTCTTGGAGATTTTACTTAAATATGGATGTAAGAAATAGCATATTTCTTTTACAGATGTAATCTAGAGTGCTTTATAGTTCATAGTAGGTACAAGTACTAACATCGGAtttgttgaaatgttttgtggAGGAAATCTGCGTTTTAGAAAATGTACTAGTATGTAATGAACCAATACatcaataaaatattgcactCTTAAA

Function

symbol description
rest Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including negative regulation of neuron maturation; negative regulation of smoothened signaling pathway; and nervous system development. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in ectoderm; endoderm; fin; head mesenchyme; and nervous system. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 27; gingival fibromatosis 5; and nephroblastoma. Orthologous to human REST (RE1 silencing transcription factor).

NR:

description
RE1-silencing transcription factor

GO:

id name namespace
GO:0021785 branchiomotor neuron axon guidance biological_process
GO:0010629 negative regulation of gene expression biological_process
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0001764 neuron migration biological_process
GO:0021610 facial nerve morphogenesis biological_process
GO:0045879 negative regulation of smoothened signaling pathway biological_process
GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning biological_process
GO:0005634 nucleus cellular_component
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function

KEGG:

id description
K09222 REST; RE1-silencing transcription factor

RNA

RNA id representative length rna type GC content exon number start site end site
XM_034309812.1 True 4848 mRNA 0.44 5 21620631 21631906

Neighbor

gene id symbol gene type direction distance location
LOC113540583 NA coding upstream 74539 21541990 ~ 21546092 (+)
LOC117598820 LOC108280985,LOC108277545 coding upstream 140189 21454118 ~ 21480442 (+)
LOC117598821 NA coding upstream 190173 21405340 ~ 21430458 (+)
LOC113527856 NA coding upstream 217907 21390903 ~ 21402724 (+)
LOC113527892 NA coding upstream 233544 21381780 ~ 21387087 (+)
LOC117598747 NA coding downstream 13946 21645852 ~ 21646623 (+)
LOC117598748 NA coding downstream 15330 21647236 ~ 21647803 (+)
LOC117598992 NA coding downstream 26596 21658502 ~ 21659107 (+)
LOC117599000 NA coding downstream 28519 21660425 ~ 21661039 (+)
LOC117598848 NA coding downstream 31189 21663095 ~ 21663540 (+)
G214825 NA non-coding upstream 3337 21617095 ~ 21617294 (+)
G214747 LOC108280967 non-coding upstream 64230 21551549 ~ 21556401 (+)
LOC117598827 LOC108280967,LOC108277545,LOC108277574 non-coding upstream 114845 21502137 ~ 21505786 (+)
G214807 NA non-coding upstream 145668 21474633 ~ 21474963 (+)
G214804 NA non-coding upstream 153905 21447993 ~ 21466726 (+)
G214829 NA non-coding downstream 2945 21634851 ~ 21635074 (+)
G215042 NA non-coding downstream 24355 21656261 ~ 21656835 (+)
G215055 NA non-coding downstream 85786 21717692 ~ 21718076 (+)
G215059 NA non-coding downstream 92705 21724611 ~ 22137078 (+)
G215064 NA non-coding downstream 142317 21774223 ~ 21807343 (+)
LOC113540569 LOC108280981,LOC108280985,LOC108277545,LOC108277574,LOC108280967 other upstream 55255 21514573 ~ 21565376 (+)
LOC113540568 LOC108280981,LOC108280985,LOC108277574,LOC108277545,LOC108280967 other upstream 107591 21482022 ~ 21513040 (+)
hopx hopx other upstream 271545 21340416 ~ 21349086 (+)
nudt6 nudt6 other upstream 596544 21011774 ~ 21024087 (+)
LOC113528520 znf518b other upstream 1447279 20022509 ~ 20173352 (+)
G215015 LOC108275153 other downstream 14174 21646080 ~ 21649152 (+)
G215022 NA other downstream 31178 21663084 ~ 22000809 (+)
G215010 LOC108275153 other downstream 32652 21664558 ~ 21711769 (+)
G215008 LOC108275153 other downstream 79288 21711194 ~ 21721059 (+)
LOC117598918 LOC108275153 other downstream 79409 21711315 ~ 21711778 (+)

Expression


Co-expression Network