nfe2l2a (nfe2l2,LOC107579917)


Basic Information

Item Value
gene id nfe2l2a
gene name nfe2l2,LOC107579917
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047599.1
NCBI id CM018545.1
chromosome length 32114633
location 17881771 ~ 17896933 (-)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026912536.2
TGTACTTCCGTCATCATCTGCTGGTAACGCGCCGGTGATTAATTTaggctgttttatttgtatttcttttttattattattatttttttaagaaatacaaAGTGGGCTATTCTAACACACTGGGAGTTACTTGTTAAGGGAAACAGTAGATTTCGCCAAAATGATGGAGATCGAGTTACCTAAAGTGCACCCAAGTCAACAGGATATGGATCTGATTGATATCCTGTGGAGGCAGGATATAGACCTGGGAGCAGGCAGAGAGGTGTTTGACTTCAGCTACAGGCAGAAGGAGGTGCAGCTGCAGCGGCagaaggagctggaggaggagaagagacaACAGATAGTGAGGGAGCAAGAGAAGGCGCTTCTTGCCCAGCTACAGCTCGACGAGGAGACTGGAGAGTTTGTGCCTCGGCCCACGCCTACCAACAATGCTCTGACGCAGGCTAACACTGCGCCTGCTGAgatcacacagAATGTGGCATTCACGGAAGAGGATGGAGACGCAATGTCATTTGACGAGTGCATGCAGCTGCTGGCAGAGACGTTTCCTCTAGTGGAGCCAGCGGAGTCTGCTCCTACTTGTCTGGATCCCTCCATTCCTCCTTGCACAGACAGCACCCATCTCATGATGCCTGGAGAAATACCCATGCTTACCCAGAATCCCCTGCTGCCAGGACCCATGGACCAGACCTGGATGGATCTGCAACACTGCCTGAACATCCAGGAGATCCTGGATATGTCCGGATACGTAAACACAGCCCAGCCTGCCAATGTTCAAGAGTCCAACTACAGCCAGTATCTGCCTAAACTAGGTGATGTCACCACCGGCACTGCCGATATGTGCTCTCCTGACTTCATGAACACTTACGATGGGGCTTTTAGCAACGTTAATCAGATCAGCCTGAAGACCCCAGACATAAACGAAAGCTTTGGACCAGATGAATTCTGCGACATGTTCTACCCTGATCTGGAGGCTAAAGTGAACAGTGCATCTCTTCCTTGTGAAGGGGGAAACACAGATGGACAGCTAGACGAGCTCCCAAATGCTACTTTGCTGAAACCCATGGACCTGCACAGCCTGTCTCCTGGAAACTTCAGCATAGAAAAAACCGAAGACATGGCTGAATTCCCAGATTCAGATTCCGGTTTGTCCCTCGATGCCAGTCCGAAAACAAGCTCTCCCGGAAAGTCCCTGCACGGCGATGGCTCTGTTGGATTCAGTGACTCAGACATGGATGAGATGGAGAGTGGTCCTGGGAGTATGGAATCTGATTATGCTGAGATGTTTCCCCTGCTGTTCCAGAGTGACAGCCCTCAACAGTCACTTCCTGAGAAATCCGGCATAACTCTGGCGCAGGAGGACACTGTTAAACAACCAAAGACGGAGCAGGCAGAGGCGAGTGGATACTCCAAACAACCCTTCACCAAAGACAAGCAGAAAAAGCGCTTGGAGGCACGGCTCTCGCGAGACGAGGAGAGAGCAAGAGCCTTGCAGATCCCATTTGCCGTGGACCTGATCATCAACCTGCCAGTGGACGACTTTAACGAGATGATGGCCAAGCACCAGTTGAATGAGGCACAGCTCGCACTCGTGCGTGACATTCGCCGGCGTGGCAAGAACAAGGTAGCAGCGCAAAACTGCCGCAAGCGCAAGATGGAGAATATCATGGGCCTGGAGTATGAGCTGGACTCGCTCAAGGAGGAGAAGGAGCGTCTGATGaaggaaaagagcaaaaacaacagcagtctAAGGGAGATGAAGCGGCAGCTCAACTCACTGTATCTGGAGGTGTTCAGCATGCTGAAGGATGAGCAGGGAAAGCCCTACTCCCCTAACGACTACTCCCTTCAGCAGACTTCAGACGGCAGTGTCTTCCTTGTCCCTCGCATTAAAAAGACTCTCGTTAAGAGCAACTAGCActtttttctgcttcttctctttcttgGTACTACATAATTCTGTAGCTAAGTACTatgcaaaagaagaaaaaaaaaaaaaactttataggCATTTTTGCTTAATCTTTAGCAGTACAGATGGCAGAACTATTATATAGTTTTTGCTTATTCTACTTTCTTAATATTCTTAATATCTCCTATATTTTGtacttctttatattttatctgAGAATGTTTTATCTTAATGGTTTGtacatacatttatactttatttgcTATTGAAATAtcaaaaaacatactgtattgtactgttttAGAATGCTACTAATTGTGTTGCGATCACTGGCACtcaaaaaagtctgtttttataTCTTAATTTAAAATTCTATTGCAATGTTATCTCTTGACTTAgggctttataaaaaaaataaacctttcatttaatttta
>XM_034304176.1
ATGTCATAATTTATTATCACCAGTTTTAACCGATAGAAAGTACAGTGTGACCTTGTTTTGGAGGAAAATTTGTTTTGAACTACAACAAAGAACAGacatcaggaaataaaaattgGAGGATATGGATCTGATTGATATCCTGTGGAGGCAGGATATAGACCTGGGAGCAGGCAGAGAGGTGTTTGACTTCAGCTACAGGCAGAAGGAGGTGCAGCTGCAGCGGCagaaggagctggaggaggagaagagacaACAGATAGTGAGGGAGCAAGAGAAGGCGCTTCTTGCCCAGCTACAGCTCGACGAGGAGACTGGAGAGTTTGTGCCTCGGCCCACGCCTACCAACAATGCTCTGACGCAGGCTAACACTGCGCCTGCTGAgatcacacagAATGTGGCATTCACGGAAGAGGATGGAGACGCAATGTCATTTGACGAGTGCATGCAGCTGCTGGCAGAGACGTTTCCTCTAGTGGAGCCAGCGGAGTCTGCTCCTACTTGTCTGGATCCCTCCATTCCTCCTTGCACAGACAGCACCCATCTCATGATGCCTGGAGAAATACCCATGCTTACCCAGAATCCCCTGCTGCCAGGACCCATGGACCAGACCTGGATGGATCTGCAACACTGCCTGAACATCCAGGAGATCCTGGATATGTCCGGATACGTAAACACAGCCCAGCCTGCCAATGTTCAAGAGTCCAACTACAGCCAGTATCTGCCTAAACTAGGTGATGTCACCACCGGCACTGCCGATATGTGCTCTCCTGACTTCATGAACACTTACGATGGGGCTTTTAGCAACGTTAATCAGATCAGCCTGAAGACCCCAGACATAAACGAAAGCTTTGGACCAGATGAATTCTGCGACATGTTCTACCCTGATCTGGAGGCTAAAGTGAACAGTGCATCTCTTCCTTGTGAAGGGGGAAACACAGATGGACAGCTAGACGAGCTCCCAAATGCTACTTTGCTGAAACCCATGGACCTGCACAGCCTGTCTCCTGGAAACTTCAGCATAGAAAAAACCGAAGACATGGCTGAATTCCCAGATTCAGATTCCGGTTTGTCCCTCGATGCCAGTCCGAAAACAAGCTCTCCCGGAAAGTCCCTGCACGGCGATGGCTCTGTTGGATTCAGTGACTCAGACATGGATGAGATGGAGAGTGGTCCTGGGAGTATGGAATCTGATTATGCTGAGATGTTTCCCCTGCTGTTCCAGAGTGACAGCCCTCAACAGTCACTTCCTGAGAAATCCGGCATAACTCTGGCGCAGGAGGACACTGTTAAACAACCAAAGACGGAGCAGGCAGAGGCGAGTGGATACTCCAAACAACCCTTCACCAAAGACAAGCAGAAAAAGCGCTTGGAGGCACGGCTCTCGCGAGACGAGGAGAGAGCAAGAGCCTTGCAGATCCCATTTGCCGTGGACCTGATCATCAACCTGCCAGTGGACGACTTTAACGAGATGATGGCCAAGCACCAGTTGAATGAGGCACAGCTCGCACTCGTGCGTGACATTCGCCGGCGTGGCAAGAACAAGGTAGCAGCGCAAAACTGCCGCAAGCGCAAGATGGAGAATATCATGGGCCTGGAGTATGAGCTGGACTCGCTCAAGGAGGAGAAGGAGCGTCTGATGaaggaaaagagcaaaaacaacagcagtctAAGGGAGATGAAGCGGCAGCTCAACTCACTGTATCTGGAGGTGTTCAGCATGCTGAAGGATGAGCAGGGAAAGCCCTACTCCCCTAACGACTACTCCCTTCAGCAGACTTCAGACGGCAGTGTCTTCCTTGTCCCTCGCATTAAAAAGACTCTCGTTAAGAGCAACTAG
>XM_034304177.1
GACTTCAGCCATTAAATGTAGAAAGATATGGATCTGATTGATATCCTGTGGAGGCAGGATATAGACCTGGGAGCAGGCAGAGAGGTGTTTGACTTCAGCTACAGGCAGAAGGAGGTGCAGCTGCAGCGGCagaaggagctggaggaggagaagagacaACAGATAGTGAGGGAGCAAGAGAAGGCGCTTCTTGCCCAGCTACAGCTCGACGAGGAGACTGGAGAGTTTGTGCCTCGGCCCACGCCTACCAACAATGCTCTGACGCAGGCTAACACTGCGCCTGCTGAgatcacacagAATGTGGCATTCACGGAAGAGGATGGAGACGCAATGTCATTTGACGAGTGCATGCAGCTGCTGGCAGAGACGTTTCCTCTAGTGGAGCCAGCGGAGTCTGCTCCTACTTGTCTGGATCCCTCCATTCCTCCTTGCACAGACAGCACCCATCTCATGATGCCTGGAGAAATACCCATGCTTACCCAGAATCCCCTGCTGCCAGGACCCATGGACCAGACCTGGATGGATCTGCAACACTGCCTGAACATCCAGGAGATCCTGGATATGTCCGGATACGTAAACACAGCCCAGCCTGCCAATGTTCAAGAGTCCAACTACAGCCAGTATCTGCCTAAACTAGGTGATGTCACCACCGGCACTGCCGATATGTGCTCTCCTGACTTCATGAACACTTACGATGGGGCTTTTAGCAACGTTAATCAGATCAGCCTGAAGACCCCAGACATAAACGAAAGCTTTGGACCAGATGAATTCTGCGACATGTTCTACCCTGATCTGGAGGCTAAAGTGAACAGTGCATCTCTTCCTTGTGAAGGGGGAAACACAGATGGACAGCTAGACGAGCTCCCAAATGCTACTTTGCTGAAACCCATGGACCTGCACAGCCTGTCTCCTGGAAACTTCAGCATAGAAAAAACCGAAGACATGGCTGAATTCCCAGATTCAGATTCCGGTTTGTCCCTCGATGCCAGTCCGAAAACAAGCTCTCCCGGAAAGTCCCTGCACGGCGATGGCTCTGTTGGATTCAGTGACTCAGACATGGATGAGATGGAGAGTGGTCCTGGGAGTATGGAATCTGATTATGCTGAGATGTTTCCCCTGCTGTTCCAGAGTGACAGCCCTCAACAGTCACTTCCTGAGAAATCCGGCATAACTCTGGCGCAGGAGGACACTGTTAAACAACCAAAGACGGAGCAGGCAGAGGCGAGTGGATACTCCAAACAACCCTTCACCAAAGACAAGCAGAAAAAGCGCTTGGAGGCACGGCTCTCGCGAGACGAGGAGAGAGCAAGAGCCTTGCAGATCCCATTTGCCGTGGACCTGATCATCAACCTGCCAGTGGACGACTTTAACGAGATGATGGCCAAGCACCAGTTGAATGAGGCACAGCTCGCACTCGTGCGTGACATTCGCCGGCGTGGCAAGAACAAGGTAGCAGCGCAAAACTGCCGCAAGCGCAAGATGGAGAATATCATGGGCCTGGAGTATGAGCTGGACTCGCTCAAGGAGGAGAAGGAGCGTCTGATGaaggaaaagagcaaaaacaacagcagtctAAGGGAGATGAAGCGGCAGCTCAACTCACTGTATCTGGAGGTGTTCAGCATGCTGAAGGATGAGCAGGGAAAGCCCTACTCCCCTAACGACTACTCCCTTCAGCAGACTTCAGACGGCAGTGTCTTCCTTGTCCCTCGCATTAAAAAGACTCTCGTTAAGAGCAACTAG

Function

symbol description
nfe2l2 Enables several functions, including DNA-binding transcription factor activity; RNA polymerase II-specific DNA-binding transcription factor binding activity; and transcription cis-regulatory region binding activity. Involved in several processes, including negative regulation of cell death; positive regulation of macromolecule metabolic process; and proteasomal protein catabolic process. Located in several cellular components, including Golgi apparatus; centrosome; and nucleoplasm. Implicated in Alzheimer's disease; cataract; hepatocellular carcinoma; macular degeneration; and tuberculosis. Biomarker of amyotrophic lateral sclerosis; asthma; chronic obstructive pulmonary disease (multiple); obesity; and visceral leishmaniasis.

NR:

description
nuclear factor erythroid 2-related factor 2

GO:

id name namespace
GO:0006979 response to oxidative stress biological_process
GO:0071379 cellular response to prostaglandin stimulus biological_process
GO:0045893 positive regulation of transcription, DNA-templated biological_process
GO:0071466 cellular response to xenobiotic stimulus biological_process
GO:0005634 nucleus cellular_component
GO:0005667 transcription regulator complex cellular_component
GO:0005737 cytoplasm cellular_component
GO:0003677 DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function
GO:0046982 protein heterodimerization activity molecular_function

KEGG:

id description
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026912536.2 True 2351 mRNA 0.46 5 17881771 17892018
XM_034304176.1 False 1837 mRNA 0.51 5 17882201 17896933
XM_034304177.1 False 1743 mRNA 0.52 5 17882201 17887072

Neighbor

gene id symbol gene type direction distance location
lnpa lnpk coding downstream 202610 17667566 ~ 17679161 (-)
atp5mc3a atp5g3,LOC108266717,LOC108424356,LOC103027531,LOC105908030 coding downstream 321698 17556819 ~ 17560073 (-)
atf2 atf2,LOC107739459,LOC107671311,LOC107657392,LOC107742976 coding downstream 325606 17529937 ~ 17556165 (-)
chn1 chn1,LOC107742958,LOC107739458,LOC106590032 coding downstream 358720 17486048 ~ 17523051 (-)
LOC113547453 chrna1,LOC108266097 coding downstream 399762 17473115 ~ 17482009 (-)
pde11a pde11a,LOC107671328,LOC107657382 coding upstream 40120 17937053 ~ 17991511 (-)
prkra prkra coding upstream 157855 18054788 ~ 18062269 (-)
casp10 NA coding upstream 171295 18068228 ~ 18076322 (-)
LOC113526302 LOC108266276 coding upstream 185182 18082115 ~ 18084871 (-)
LOC113525937 adam23,LOC108267022,LOC108424345 coding upstream 191690 18088623 ~ 18114405 (-)
G84411 NA non-coding downstream 48182 17833375 ~ 17833589 (-)
LOC117597384 NA non-coding downstream 137746 17740637 ~ 17744025 (-)
G84394 NA non-coding downstream 153774 17726653 ~ 17727997 (-)
LOC117597450 NA non-coding downstream 450340 17407218 ~ 17431431 (-)
G84227 NA non-coding downstream 489824 17391684 ~ 17391947 (-)
G84881 NA non-coding upstream 234477 18131410 ~ 18131998 (-)
G84880 ino80d,LOC106582458 non-coding upstream 236469 18133402 ~ 18133689 (-)
G84882 LOC108266575 non-coding upstream 237903 18134836 ~ 18135614 (-)
G84883 LOC108266575,LOC108424342 non-coding upstream 238736 18135669 ~ 18137083 (-)
G84975 xirp2 non-coding upstream 643420 18540353 ~ 18555865 (-)
evx2 evx2,LOC107657379,LOC107671304 other downstream 181791 17695290 ~ 17699980 (-)
sp3a sp3 other downstream 500599 17371979 ~ 17381172 (-)
mettl8 mettl8 other downstream 841928 17028237 ~ 17039843 (-)
si:dkey-91i10.2 LOC108266132,LOC106530433,LOC107658202 other downstream 1475293 16370227 ~ 16406478 (-)
G83554 NA other downstream 1660905 16219964 ~ 16220866 (-)
LOC113526313 baz2b other upstream 1016454 18913387 ~ 18968492 (-)
grb14 grb14 other upstream 1546158 19443091 ~ 19494515 (-)
steap3 steap3,dbi,LOC107560815,LOC107747240 other upstream 1671816 19568749 ~ 19586103 (-)
G85848 NA other upstream 2329795 20226728 ~ 20237615 (-)
abcb6b LOC108266852,LOC108423985,LOC107596549,LOC107750068 other upstream 2497538 20394471 ~ 20423244 (-)

Expression


Co-expression Network