smad3b (smad3,LOC108264458,LOC108424035,LOC107740443,LOC107755098)



Basic Information


Item Value
gene id smad3b
gene name smad3,LOC108264458,LOC108424035,LOC107740443,LOC107755098
gene type misc
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information


Item Value
chromosome id NC_047600.1
NCBI id CM018546.1
chromosome length 31307711
location 13932539 ~ 13956351 (+)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence


>TU117370
aaaaaaatagattttgtaattcttatttttgcataacAACCAGACAGGAGAGTGCAGCAGTGTATTTTTGCTGTCActtagtgtatattattatgtCAGAGCCTGTAAGAAGGGCCCCAATGAGTAGCACAAACCCacccattttacatttattttttccccctctctctctctcatgcttttTGCTTTGCTACTTCTTgtctgcagcctcagctttacTAAAGTGTTTAGGCATTGAAAGCCTGATGAATCAAGAAACATTGCACGCAGCATCTACGGCTATTCAAGGCAGTATATGTAGTAtcagagaaccaggaggaaCTCCTGTTTTTTATAGAGTGATTGTcagtggtggtttttttttttttttttttttctcttggcaGTCCTAGTCAAATTTCTGAACCTCGAGCTTCAGAATAGCTAGACCCAGGCTGCCTGTGGGTGGCTGGATCAGGGCCCATGTTTATCAAGCGTTTAACAGTATGCTCATCCAAGATCATTGCCCTCTACTGCTTTTACCCTTACTCTTACTTACATATATGTGGATATGAGAGTAGGCCAATCCCATCTGAAGTTCCTTTGTTCACCGATATTTGTTCACCGATATATGGATGAAGACGGAACACTTGCTCTCACTATACGTACACCTTCACATCCTATGGGTGCGCCGCAGTCGCCTGTGGAGTTAATTCACTCAGTATACCATTATGTATGGCACATCAAACAGAGAATTCAAACTCAGGACCATCTGGCCACTTGAAAGAAAAATACTTCATGCACACATTACTATATAGTCAATTCTGTGTCACTGCCAATTATTTTTGTGTCAAAGGAAATGGATGGTCTATTGTAAATTGAAGACTataaagatatttttgaaagaATGTTAGGATGAGGAAAACACTGCTGGCAGCTCCTGATGTGTGCTCATATTTTTACTACAGAGGTTGAATTCTCACATGGGATGCTCtgttctcatggctggattgttTTTGAGCCAGGTCCTATCAGTAAGATGGGCATATTATCTTGTATGTAGTCTAAAGATtatgattatataattacaCTGACTGGATCCTTTTGATTAATTGCATGGTCTTGCAATTCTTGAATTTCCAACAAAGATCAGCAGTTGCACTTTGTTTGAGCAGGCACACTTCAGACTGCAGCTGCCTCCTGCTGATAGCTTAGGCAATTACATGTTGAAATATTgctcactctgtttctctcaaaGCTCTTAGAAAAAACTTGCTTATGAAAAATGAGCTTATGTCATCAATGAAGTCATAAGGAACTGCATTTACAGAATTGATCCCTGTGGTTTGATCTCCCTTTAACATAGAACCGTAAACTCTGCGTCCAGTGCTGTGGACCCTGCTAGAGCTCCTGTAACAGTGTCAGCAGTGTCCATGTAGGGTCATGattcttgtcattttttttcaaattgaaATACTGCTTTGTAGTATCATGTTCTTATCCATACACTCATTATGTGAGGCAAATGTAAATCTGTTTCTGTCTTATGGTTTCAATACGTAATAATTACccttatatatttttcagatgTTGCTTAGTTTTTGTTTGCCTGAAATGTGCTTACTCTCTGCTACTGTACCTACATAGCTTTTC
>XM_026927477.2
GCGGCGACATTACTGCGCTTCTGCACGCAATGCTCTACAGAGTTGCTGTTTTAGCCGTCAGCTAAATGTCTGTTGCAGGAACTAAAGTTTCGTTAACTGATATTTGGCGGATATTTTGGTGAAATCCTACGGGATTACTTTTTCAAACAAGCGATTGACTGAGCGTGCAAAGAGGCAGAGAGGTGAAACGAACATGTCTATTCTGCCGTTCACACCTCCGATTGTGAAGAAGCTCCTCGGATGGAAAAAGGGAGAGCAGAATGGACAAGAAGAGAAATGGTGTGAAAAGGCGGTGAAGAGTCTCGTGAAGAAGCTAAAGAAGACGGGGCAACTTGACGAATTGGAGAAGGCCATTACTACCCAGAATATAAATACGAAATGCATAACCATACCGAGGTCTTTGGATGGGCGTCTGCAGGTGTCTCACAGAAAAGGCCTCCCTCATGTAATCTACTGCCGGCTATGGCGCTGGCCTGACCTGCAGTCACACCACGAGCTGCGTGCTATAGACCAGTGCGAGTTCGCTTTCCACATGAAGAAGGACGAGGTGTGTGTCAACCCCTACCATTACCAGCGCGTGGAGACACCAGttCTTCCTCCAGTACTGGTTCCCCGACACACTGATATCCCTGCTGAGTTTCCCCCGCTGGATGACTACAGCCATTCTATCCCTGAGAACACCAACTTTCCTGCAGGCATAGAGCCTCTGATCAACTACATACCTGAGACACCCCCTCCAGGGTATCTCAGTGAAGATGGTGAAAGCAATGATCAACAGAATCGCAGCATGGACACAGGTTCCCCAAACTTGTCACCTAACCCTGTTTCCCCTGCAAGTAGCAACCCTGATCTGCAACCGGTGACATATTGTGAGTCAGCGTTCTGGTGCTCCATCTCTTACTACGAGCTGAACCAGCGGGTAGGGGAGATATTCCATGCCTCGCAGCCCTCTCTGACCGTGGATGGCTTCACTGATCCGTCCAATGCTGAGAGATTCTGCCTGGGTTTGCTGTCCAATGTTAACCGCAACACCGCTGTGGAGCTCACACGCAGACATATTGGTCGGGGAGTGCGGCTGTACTACATAGGTGGTGAAGTGTTTGCAGAGTGTCTGAGTGACAGTGCCATCTTTGTCCAGAGTCCTAATTGCAACCAGCGCTATGGCTGGCACCCCGCCACCGTGTGTAAGATTCCTCCAGGCTGTAATCTAAAAATCTTCAATAACCAGGAGTTTGCGGCTCTGTTGGCTCAGTCGGTGAATCAGGGATTTGAGGCTGTGTACCAATTGACCCGCATGTGCACAATCCGCATGAGTTTCGTCAAAGGCTGGGGAGCAGAATACAGGCGCCAGACTGTAACCAGCACCCCCTGTTGGATAGAGCTACACTTAAACGGCCCCCTGCAATGGCTAGACAAGGTGCTCACCCAGATGGGCTCACCCAGCATCCGCTGCTCCAGTGTGTCATAGGAGACCCAGCACCACCGGCTTCACAACCAGGAACCACCACCCGCCTGCATACTAACCGAGAAAACATGAAAAGGCtggacaggcagacagacagacagacagacagacaaacatacagacatacagacatcCTCTCAAGTGTTTCCTTTTAGTCTCACTCCACTGCTTGCCGGTCCAGTCATTCCCATACACACAGAGTTTTGAGCACTTTCTGTTGCTGATACCTATACAGCATGGCTTGTATAGCTGTGCATGAAATGTAGGTTTGTTTTGGTCATACAaagatagatatatattttggctgtttttttttttttacatttaattttaagcTTGGCTTAAAACATGAGGTATTGAACCTTACAGAGTTTAAACACTTTTCATATTCATTGAAGATGGATATGGATATATAACTGGTGAagtagatttttattattaatcacaTACATAAAGCTTGCAGTACTTGAAAAGCTGCAACACTATGTAATTTGGGGAAACTATCTGAATTTCTCTCAGGCCCAGCAGTTTGCTGTGCATGCATTTAGCAATTTCATAGGCCCTTAACCTCAGAGGGTTAGTACTGCATCCCCACGGCCTTCATTCAAGTGGCTGCGTGGGAGTATATCCCTAGCTGTTGGCTGTTTTAAAGTGAACAGTAGCTAGGTACTGCTCTTATGGTGTGTTGGCGCTCACATGCCATATTGGGCTACATGCACTGAGCAGTTCAGCACAATTTATAGGATGGTTCAATGCTGTTAACCTGGTTATTCTTTTTCTTGTAGTATGAAAACTAGATGTCTGTCTCTTTTCAAGATGATATAAAGCACCTCTTGATACAAGATGTGATGCCTGAAAGATGTATTTAAGATTTATGTTGTGACTTGGAGCTGTTTTTATGCGATACCATGTAATTCAGAtgctactaattttttttttttttcgacacTGGTTCCAGAAAAATATCCAGCAGGTATAAATCAGTATGACACGTTTTTGCTCCAATATTACCCGGAAAaggttttacatttacaacttACTGCTGTGCTATTAGGGGAACATTGGATGAATTGTGTTTGTAGTGCCCAACAACACATTTGGGATTTGGTAAGGAACTTATCAAACGTGCTGTTCTGTAGAGAGGCAGATGTCTTGCAGCTGCAATTATGTTTTGTGTgataaatcatgttttaaatgttccgCTGTTTTACTACATCCGAGAAATAGTCAGCACACGAGCCGGCATAGAGCCTTTGTTCCACTTTCTTTATCTTCAGAGCATGTGAACAGTTTCTGATTTTCATCAATATAAAACTAAGCTCAAAGTAAATAAGGTTACTCACCATGGTCGAGTAGACTGCATTTAAAAGACCAGCGACAGCTTTCTCAGTCGTTCTCCATAGCAAGTTGCAGTGCAGTTTACCTGGTAATGGCTACGTGTGGCTCACAAGATCAGACTAGGAAAATGTGATAAGGGTGTCCCAGAAAAACAATGTATATCATTAACTATGCGTTAACCTTAAAAGCCCTTGGTTGTAATGTTAGAAGCCCTTGGTATGTTTTGTAtcataaatactgaaaatgGTGCATTTTTGTGGTACTTAGTCCAGTGTAGCACAACCTTAACCATGTGAAGCACTTGTCTTTACTACTCTATCAGAGAGTAAACAAATCATTCTCTTCAACGCTGGAAATTGGAAGTTTGTCAGTGACATAACTGTATCCATTGTTTCAGAAAAActgaaatttgtaaaaaaaaaaaaaaaaaaagaaagaaaaaaaaaaatagattttgtaattcttatttttgcataacAACCAGACAGGAGAGTGCAGCAGTGTATTTTTGCTGTCActtagtgtatattattatgtCAGAGCCTGTAAGAAGGGCCCCAATGAGTAGCACAAACCCacccattttacatttattttttccccctctctctctctcatgcttttTGCTTTGCTACTTCTTgtctgcagcctcagctttacTAAAGTGTTTAGGCATTGAAAGCCTGATGAATCAAGAAACATTGCACGCAGCATCTACGGCTATTCAAGGCAGTATATGTAGTAtcagagaaccaggaggaaCTCCTGTTTTTTATAGAGTGATTGTcagtggtggtttttttttttttttttttttctcttggcaGTCCTAGTCAAATTTCTGAACCTCGAGCTTCAGAATAGCTAGACCCAGGCTGCCTGTGGGTGGCTGGATCAGGGCCCATGTTTATCAAGCGTTTAACAGTATGCTCATCCAAGATCATTGCCCTCTACTGCTTTTACCCTTACTCTTACTTACATATATGTGGATATGAGAGTAGGCCAATCCCATCTGAAGTTCCTTTGTTCACCGATATTTGTTCACCGATATATGGATGAAGACGGAACACTTGCTCTCACTATACGTACACCTTCACATCCTATGGGTGCGCCGCAGTCGCCTGTGGAGTTAATTCACTCAGTATACCATTATGTATGGCACATCAAACAGAGAATTCAAACTCAGGACCATCTGGCCACTTGAAAGAAAAATACTTCATGCACACATTACTATATAGTCAATTCTGTGTCACTGCCAATTATTTTTGTGTCAAAGGAAATGGATGGTCTATTGTAAATTGAAGACTataaagatatttttgaaagaATGTTAGGATGAGGAAAACACTGCTGGCAGCTCCTGATGTGTGCTCATATTTTTACTACAGAGGTTGAATTCTCACATGGGATGCTCtgttctcatggctggattgttTTTGAGCCAGGTCCTATCAGTAAGATGGGCATATTATCTTGTATGTAGTCTAAAGATtatgattatataattacaCTGACTGGATCCTTTTGATTAATTGCATGGTCTTGCAATTCTTGAATTTCCAACAAAGATCAGCAGTTGCACTTTGTTTGAGCAGGCACACTTCAGACTGCAGCTGCCTCCTGCTGATAGCTTAGGCAATTACATGTTGAAATATTgctcactctgtttctctcaaaGCTCTTAGAAAAAACTTGCTTATGAAAAATGAGCTTATGTCATCAATGAAGTCATAAGGAACTGCATTTACAGAATTGATCCCTGTGGTTTGATCTCCCTTTAACATAGAACCGTAAACTCTGCGTCCAGTGCTGTGGACCCTGCTAGAGCTCCTGTAACAGTGTCAGCAGTGTCCATGTAGGGTCATGattcttgtcattttttttcaaattgaaATACTGCTTTGTAGTATCATGTTCTTATCCATACACTCATTATGTGAGGCAAATGTAAATCTGTTTCTGTCTTATGGTTTCAATACGTAATAATTACccttatatatttttcagatgTTGCTTAGTTTTTGTTTGCCTGAAATGTGCTTACTCTCTGCTACTGTACCTACATAGCTTTTCCTTACATTAACTGTTTAAGCTATTGTTATATTGCTTCATTTTGTTATTcaaaaatttgtaataaaatatgtattttaaactgGA

Function


symbol description
smad3 Enables several functions, including DNA-binding transcription factor binding activity; SMAD binding activity; and enzyme binding activity. Contributes to DNA-binding transcription factor activity. Involved in several processes, including cell surface receptor signaling pathway; positive regulation of nitrogen compound metabolic process; and regulation of gene expression. Located in chromatin; cytosol; and nucleus. Part of heteromeric SMAD protein complex and receptor complex. Implicated in Loeys-Dietz syndrome 3; Lynch syndrome; and pancreatic cancer. Biomarker of cervical squamous cell carcinoma; endometrial cancer; and prostate cancer.

NR:

description
mothers against decapentaplegic homolog 3, partial

GO:

id name namespace
GO:0007179 transforming growth factor beta receptor signaling pathway biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0005634 nucleus cellular_component
GO:0005667 transcription regulator complex cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0005515 protein binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function

KEGG:

id description
K23605 SMAD3; mothers against decapentaplegic homolog 3

RNA


RNA id representative length rna type GC content exon number start site end site
TU117370 False 1632 lncRNA 0.39 1 13954636 13956267
XM_026927477.2 True 4960 mRNA 0.42 9 13932539 13956351

Neighbor


gene id symbol gene type direction distance location
smad6b smad6 coding upstream 36039 13872175 ~ 13896500 (+)
zwilch zwilch coding upstream 130943 13789823 ~ 13801596 (+)
map2k1 map2k1,LOC107583767,LOC107672217,LOC107596971,LOC107686295 coding upstream 152262 13768111 ~ 13780277 (+)
rab11a rab11a,LOC105007892,LOC100698633,LOC106591986,LOC103378951,LOC106588008,LOC106562755 coding upstream 280834 13645900 ~ 13651705 (+)
slc24a1 slc24a1 coding upstream 319746 13589003 ~ 13612793 (+)
iqch iqch coding downstream 5478 13961829 ~ 14027467 (+)
c6h15orf61 c4h15orf61,zgc:162898,cunh15orf61,LOC103025902,LOC107738714,LOC107686305,LOC107583911,LOC107718314 coding downstream 30473 13986824 ~ 13988185 (+)
pias1b pias1b,pias1,LOC108264782,LOC108424062,LOC107596961 coding downstream 89532 14045883 ~ 14073956 (+)
morf4l1 morf4l1,LOC107596963,LOC107686360,LOC107738770,LOC107708218,LOC107672187 coding downstream 122390 14078741 ~ 14088899 (+)
uacaa LOC108264780 coding downstream 135399 14091750 ~ 14106349 (+)
G98996 NA non-coding upstream 8226 13891424 ~ 13924313 (+)
LOC113534555 NA non-coding upstream 86394 13837717 ~ 13846145 (+)
G98960 NA non-coding upstream 147764 13740823 ~ 13784775 (+)
LOC113534369 NA non-coding upstream 174050 13757853 ~ 13758489 (+)
G98945 NA non-coding upstream 240971 13691346 ~ 13691568 (+)
G99006 NA non-coding downstream 33591 13989942 ~ 13990153 (+)
G99260 kif23 non-coding downstream 301561 14257912 ~ 14260742 (+)
G99261 NA non-coding downstream 305090 14261441 ~ 14262517 (+)
G99276 ighmbp2 non-coding downstream 361246 14317597 ~ 14318654 (+)
G99362 NA non-coding downstream 673984 14630335 ~ 14631361 (+)
G98972 NA other upstream 143149 13785095 ~ 13789390 (+)
G98946 megf11 other upstream 216773 13691607 ~ 13715766 (+)
nlrc5 nlrc5 other upstream 1074005 12837299 ~ 12858534 (+)
uri1 uri1 other upstream 2742430 11151714 ~ 11190109 (+)
vps9d1 vps9d1 other upstream 2765737 11145154 ~ 11166802 (+)
skor1b skor1 other downstream 78877 14035228 ~ 14042452 (+)
G99341 synm other downstream 564450 14520801 ~ 14524480 (+)
carmil2 carmil2,rltpr other downstream 1344131 15300482 ~ 15346146 (+)
G100306 NA other downstream 2393106 16349457 ~ 16349787 (+)
G100345 NA other downstream 2643906 16600257 ~ 16601067 (+)

Expression



Co-expression Network