idh2 (idh2,LOC107714782,LOC107691122,LOC106514339)


Basic Information

Item Value
gene id idh2
gene name idh2,LOC107714782,LOC107691122,LOC106514339
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047600.1
NCBI id CM018546.1
chromosome length 31307711
location 18681517 ~ 18732814 (+)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026932450.2
GTGGGGGGCACACGGGCATATTGCCGCGCACTGTAATTCATTCTGCTCTTCATTTCGTTCGGAGTGGTCGAACAGAAGCCGTATATCAGCTAAACATGGCAGGTTATCTAAAGGTTCTCAGCTCTCTGACCAGGTCTGCTACTGCTTTATCCAAAAGCCCCGCGGTCCTTGCTGCTCAAGCTTGCCAGACTTTACAGCAGAGGAACTATGCTGACAAGCGCATCAAGGTGGCCCAGCCAGTGGtggagatggatggagatgaGATGACTAGGATAATCTGGGAATTCATCaaagaaaagCTCATCCTGTCCAATGTTGATATGGAGCTGAAGTACTTTGACCTGGGCCTCCCCTACCGTGACCAGACTGATGACCAGGTCACCATTGACTCTGCCTTAGCAACTAAGAAGTACAATGTTGCTGTCAAGTGTGCGACCATCACTCCCGACGAGGCCAGGGTCGAAGAATTCAAGTTgaagaaaatgtggaaaagtccCAATGGAACCATCAGAAACATCTTGGGTGGCACAGTTTTTCGTGAACCCATCATCTGCAAGAACATTCCCAGACTTGTTCCTGGTTGGACACAGCCCATCACAATTGGCAGACATGCCTTTGGTGACCAGTACAGAGCCACAGACTTTGTTGTGAATACACCAGGCAAATTTATGATCAGCTTTATTCCAGCTGATGGAAGCAAAGGCCAGGAGTGGGAAGTGTTCGATTTCCCAGGGGGTGGCTGTGGAATGGGCATGTACAATACTGATGAGTCCATCACTGGGTTTGCTCACAGCTGCTTCCAGTATGCTATCCAGAAAAAATGGCCTCTATACATGAGCACCAAGAATACCATCTTGAAAGCGTATGATGGGCGCTTCAAGGACATCTTCCAGGACATCTTCGAGAAGAAATACAAGCCTGAGTTTGACAAGCTGAAGATCTGGTATGAGCACAGGCTTATTGATGACATGGTGGCACAAGTGTTGAAGTCCTCTGGTGCTTTTGTTTGGGCTTGCAAGAACTATGATGGAGATGTCCAGTCTGATATTTTGGCTCAAGGTTTTGGCTCCTTGGGCTTGATGACCTCTGTTCTTGTGTGCCCTGATGGAAAGACCATTGAGGCTGAAGCTGCCCATGGCACAGTAACTAGGCATTACCGTGAGCATCAGAAGGGAAGACCAACCAGCACCAATCCTATTGCGAGCATCTTTGCCTGGACCAGGGGACTGGAGCACAGAGGCAAGCTTGATGGAAACCCAGATTTGATCAAGTTTTCTCAGACTCTGGAACGAGTGTGTGTGGACACTGTGGAGAATGGTGTCATGACCAAGGATCTGGCAGGCTGCATTCATGGGCTCTCAAATGTCAAGCTTAATGAGCACTATGTCAACACCACGGACTTCCTAGATGCAATCAAGACCAACCTGGACAAAGCTCTGGGTAAATGAAGGAGGAGGACACTGAAGCACATCTTTTCCTTTTTGTACCTCATTTAACTTAAATGTCATTGTAACCATAACCATTATTGCTGAAGGGAAAAGTTGAAAAGAAacctatgttttttttctgcagcagTGCTGTTGGCTAGTGTTAGCTAAACTGTAAGTGTCATCAGTCCACTCCAATTCCAAACTGTCCTTATACCCGCAaggttttagtttttaaatatgaaGTACTGTATGTAATACTGTATTAAACCTGGAAACAAAGGTGAATGGCCATTTTGGAAACCTTCTAATAAA

Function

symbol description
idh2 Predicted to enable NAD binding activity; isocitrate dehydrogenase (NADP+) activity; and magnesium ion binding activity. Predicted to act upstream of or within glyoxylate cycle; isocitrate metabolic process; and tricarboxylic acid cycle. Is expressed in several structures, including blastoderm; brain; digestive system; pectoral fin bud; and renal system. Human ortholog(s) of this gene implicated in D-2-hydroxyglutaric aciduria 2; acute myeloid leukemia; hepatocellular clear cell carcinoma; intrahepatic cholangiocarcinoma; and lung cancer. Orthologous to human IDH2 (isocitrate dehydrogenase (NADP(+)) 2).

NR:

description
isocitrate dehydrogenase [NADP], mitochondrial

GO:

id name namespace
GO:0006099 tricarboxylic acid cycle biological_process
GO:0006102 isocitrate metabolic process biological_process
GO:0051287 NAD binding molecular_function
GO:0004450 isocitrate dehydrogenase (NADP+) activity molecular_function
GO:0000287 magnesium ion binding molecular_function

KEGG:

id description
K00031 IDH1, IDH2, icd; isocitrate dehydrogenase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026932450.2 True 1742 mRNA 0.46 11 18681517 18732814

Neighbor

gene id symbol gene type direction distance location
cd81b cd81b,LOC107690398,LOC108435318,LOC107554556,LOC107715206,LOC107691158,LOC107746582 coding upstream 439908 18224061 ~ 18241609 (+)
reln reln coding upstream 493033 17761517 ~ 18188484 (+)
kti12 kti12,LOC107715238,LOC107725737,LOC107562123 coding upstream 1079343 17581883 ~ 17602174 (+)
sec11a sec11a,LOC107691153,LOC107562127 coding upstream 1139864 17530434 ~ 17541653 (+)
slc28a1 LOC108263923 coding upstream 1303177 17363125 ~ 17378340 (+)
zgc:162879 NA coding downstream 427172 19159986 ~ 19239977 (+)
psmd8 psmd8,LOC108413249,LOC107672785,LOC107554985,LOC107714529 coding downstream 546336 19279150 ~ 19283703 (+)
spred3 spred3,LOC108264009,LOC107554984 coding downstream 562678 19295492 ~ 19308801 (+)
LOC113526414 LOC108263931,LOC108265089,LOC108443054 coding downstream 621312 19354126 ~ 19360323 (+)
lmo2 lmo2,LOC107554475 coding downstream 785789 19518603 ~ 19526473 (+)
G101422 NA non-coding upstream 79331 18601922 ~ 18602186 (+)
G101417 NA non-coding upstream 83811 18597491 ~ 18597706 (+)
G101411 NA non-coding upstream 111752 18568998 ~ 18569765 (+)
G101402 NA non-coding upstream 132264 18549045 ~ 18549253 (+)
LOC117597608 NA non-coding upstream 133228 18547925 ~ 18548289 (+)
G101436 NA non-coding downstream 10266 18743080 ~ 18743291 (+)
G101444 NA non-coding downstream 20267 18753081 ~ 18753287 (+)
LOC113538061 NA non-coding downstream 69822 18802636 ~ 18816962 (+)
G101583 NA non-coding downstream 136286 18869100 ~ 18869377 (+)
G101586 NA non-coding downstream 139428 18872242 ~ 18872458 (+)
G101419 NA other upstream 82142 18598714 ~ 18599375 (+)
G101403 NA other upstream 129793 18551446 ~ 18551724 (+)
LOC113539654 NA other upstream 1188425 17489546 ~ 17493092 (+)
LOC117597546 LOC107707548,LOC106676627,LOC106676599,LOC106675328,LOC106675542,LOC107675252 other upstream 1238049 17400426 ~ 17443468 (+)
rgma NA other upstream 2000724 16657601 ~ 16680793 (+)
G101434 znf710 other downstream 5529 18738343 ~ 18739998 (+)
G101466 NA other downstream 60821 18793635 ~ 18794273 (+)
sema4ba sema4b,sema4ba,LOC107691120,LOC107556264,LOC107714785 other downstream 224614 18957428 ~ 19122497 (+)
G101602 NA other downstream 389798 19122612 ~ 19123877 (+)
cdon cdon other downstream 1187235 19920049 ~ 19969787 (+)

Expression


Co-expression Network