alas2 (alas2,LOC108265738,LOC108441648,LOC107555603,LOC107745783,LOC107549233,LOC107731137)


Basic Information

Item Value
gene id alas2
gene name alas2,LOC108265738,LOC108441648,LOC107555603,LOC107745783,LOC107549233,LOC107731137
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047602.1
NCBI id CM018548.1
chromosome length 30442583
location 11841583 ~ 11849987 (+)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026923200.2
TGGGCAGTAAAGCAGGTTGGTGGGTATGTTGCTGAGAGGGTGGACCCAGAAACTGCGCTTATTGCGCTCACTCTCCTGCACACTCGGTCCAGTGAACTGTCGCATTTGTTCACGTTCAGACGTTCGTCCTCAGTGCAGGTCAACAGCTGCTGAAGTCATGTCTGCCTTTCTGCATCGCTGTCCATTTCTGAAGTCTGCTCCGGGTCCGGCGCTGAGACATGTGGGGGGATTTCTGGGTATGGCTGAACGATGCCCCATCATCGTGCGCCAGGTCACCGTCCAGTCCACGCAGAGTCATGATGAAAAAGGCTTGCTGCCGCAGAAGGAAGTCAAGCGCTCCTTGGCTACATCTGCTGCTCAGGTTGCTGTGTCCATGACCGAGGCCTGTCCCTTTGTCTCCTCTAAGATTGGACTAGTTAAAGCCAGCCCTCAAGTTCAGGAGGATGTCCACTCAGCGCTGCCTCCTATTGCAGAGGAGGAAGTCACTTCAGGAACGATCAGTTCTGTGTTTAGTGGCTTACAGGGCCTTCAGTCATCTTTTCCATCCCACCTTCTCAAGGACAACATTGTTGGATCCAGTTTTGACTATGATGACTTCTTCACCCAGAAGATCATTGAGAAGAGGAATGACCACACCTACCGTGTCTTTAAGACGGTGAATCGGTTTGCGGATGTTTTTCCCTTTGCTGAGGATTATTCCTTTCCAGGACGCCTTGGCTCACAGGTGTCTGTTTGGTGCAGCAACGACTACTTGGGCATGAGTCGCCATCCACGCGTCATTAAAGCAATATGGGATGTTTTGGAAAAACATGGTGCAGGAGCAGGTGGCACCAGGAATATCTCTGGGACAAGTTACTACCATGTGGCTCTTGAGAAAGAACTGGCTCTTCTTCACCAAAAAGATGCAGCCCTTGTCTTCTCCTCATGCTTCGTGGCCAATGATTCCACCCTCTTCACTCTAGCAAAAATGCTTCCAGGCTGTGAGATCTATTCAGACATGGGGAACCATGCATCCATGATTCAGGGCATCAGGAACAGTGGAGCCAAACGTTTCATCTTCCGACACAATGATGCAAGACATCTAGAAGAGCTGCTCAGTCGCTCTGATCCGAGGACACCTAAGATTGTGGCATTTGAGACAGTGCACTCCATGGATGgAGCTATCTGCCCCCTAGAGGAGCTGTGTGACGTTGCACACAAATATGGCGCTCTCACCTTTGTGGATGAGGTTCATGCAGTAGGCCTGTATGGACCACATGGAGCAGGGGTCGGTGAGAGAGACGGCGTCATGCACAAGATCGATATTGTCACTGGTACACTGGGTAAGGCATTTGGCTGTGTAGGGGGCTACATAGCCAGCACTGCTGCGCTGGTGGACACAGTGCGATCCTATGCAGCAGGCTTCATCTTCACCACCTCACTGCCTCCCATGGTGCTGGCTGGAGCTCTGGAGTCTGTACGGGTTCTGAGGAGCTCAGAGGGTCAGGCTCTGCGCCGAGCTCACCAGAGGAATGTTAAACACATGAGGCAGCTTTTGTTGGATGCAGGTCTGCCTGTCATCAATTGCCCAAGCCACATTATCCCCATACGGGTTGGAAATGCAGAGAAAAACTCCAAGGTGTGTGACATTCTGCTGGAGAGACACAACATCTATGTACAGGCGATAAACTACCCGACTGTGCCACGTGGAGAAGAGCTGCTGCGTTTGGCACCATCCCCTTTCCACAACCCCGTCATGATGGATTACTTTGTGGAGAAATTGGTGGATGTATGGCAGGAAGTTGGACTGCCACTCAATGCCCCTGCAACAGCCTCCTGCACTTTCTGTGACCGTCCCCTCTACTTTGACCTCATGAGCGAGTGGGAGAAAAGTTACTTTGGCAATATGGAACCAAGATATATTACAGTTGCAGCacaataagaaaaatgaaagggAAGAGAGATGGAAAGCAACATTCAGTATAatcagctgaaaagatcattattaaagaaaaaaatcataactgCTGAGATATCTTCTTTTACACTGTCATACATATTGCTGCCTGCTGCAGTTACGTCATTAGTACTGGCTTTGGTGCTGTTGGATTATATACCTTTTCATGGAATATTAGGTCTGTGTCCCCTCTGCATTATTAAAAACCTGCACATGGGCACTTTTAATggaaactatttaaaaatatttaaatactttaattttttattatttatattatattttattcacaatcCATATCTATGTCTCTTATGCATTAGACTTGAGTTCGAATGCATTAGACTTGAGTTTGACTTGAGTTTGAAAAGCTTTATCCCAAAGTCTTGACTACAGCCTAAATAGGCAACAACAAACATGGTCTTACACTTGCTAATTTCACAACACCATGTTCTAAAAAAGATATGAAAGTTAAGGTTATTGTTAGGGGCAGGGTTGGGATTCGTACCTTTTCTTACAACTCCAAATCAAATTGGTGTATTTAATTGGAATTTACACTGCACATTAACTTACACTAGTTTGCTAGGTAACCGGCTAATCATTATTTTCTCTAATTTTCCAaattacatgtacatttttagGCTTCAGAGTCCTTTTAAACAGCAGAACCTTTGTGATAGCAGCTGAGAAATACAGCCCACCTCAGCTGAAGCTTAAACACTGTGATGCACCTGTTATCTTATTAAATTTCCTATTTGGGTTTTGCATTTAGGCAGGAGTGTGCATAATGATCCCAGGAATATACAGAATCAATCTACTTTGCTTCTtcagatcattttattttcatgaggTCAATGTTttatgagaaataaaatcaaacaacacTCTTGAA
>XM_034306542.1
TTGGACCAAAAGTATTCTGCTTGCTGCCGCAGAAGGAAGTCAAGCGCTCCTTGGCTACATCTGCTGCTCAGGTTGCTGTGTCCATGACCGAGGCCTGTCCCTTTGTCTCCTCTAAGATTGGACTAGTTAAAGCCAGCCCTCAAGTTCAGGAGGATGTCCACTCAGCGCTGCCTCCTATTGCAGAGGAGGAAGTCACTTCAGGAACGATCAGTTCTGTGTTTAGTGGCTTACAGGGCCTTCAGTCATCTTTTCCATCCCACCTTCTCAAGGACAACATTGTTGGATCCAGTTTTGACTATGATGACTTCTTCACCCAGAAGATCATTGAGAAGAGGAATGACCACACCTACCGTGTCTTTAAGACGGTGAATCGGTTTGCGGATGTTTTTCCCTTTGCTGAGGATTATTCCTTTCCAGGACGCCTTGGCTCACAGGTGTCTGTTTGGTGCAGCAACGACTACTTGGGCATGAGTCGCCATCCACGCGTCATTAAAGCAATATGGGATGTTTTGGAAAAACATGGTGCAGGAGCAGGTGGCACCAGGAATATCTCTGGGACAAGTTACTACCATGTGGCTCTTGAGAAAGAACTGGCTCTTCTTCACCAAAAAGATGCAGCCCTTGTCTTCTCCTCATGCTTCGTGGCCAATGATTCCACCCTCTTCACTCTAGCAAAAATGCTTCCAGGCTGTGAGATCTATTCAGACATGGGGAACCATGCATCCATGATTCAGGGCATCAGGAACAGTGGAGCCAAACGTTTCATCTTCCGACACAATGATGCAAGACATCTAGAAGAGCTGCTCAGTCGCTCTGATCCGAGGACACCTAAGATTGTGGCATTTGAGACAGTGCACTCCATGGATGgAGCTATCTGCCCCCTAGAGGAGCTGTGTGACGTTGCACACAAATATGGCGCTCTCACCTTTGTGGATGAGGTTCATGCAGTAGGCCTGTATGGACCACATGGAGCAGGGGTCGGTGAGAGAGACGGCGTCATGCACAAGATCGATATTGTCACTGGTACACTGGGTAAGGCATTTGGCTGTGTAGGGGGCTACATAGCCAGCACTGCTGCGCTGGTGGACACAGTGCGATCCTATGCAGCAGGCTTCATCTTCACCACCTCACTGCCTCCCATGGTGCTGGCTGGAGCTCTGGAGTCTGTACGGGTTCTGAGGAGCTCAGAGGGTCAGGCTCTGCGCCGAGCTCACCAGAGGAATGTTAAACACATGAGGCAGCTTTTGTTGGATGCAGGTCTGCCTGTCATCAATTGCCCAAGCCACATTATCCCCATACGGGTTGGAAATGCAGAGAAAAACTCCAAGGTGTGTGACATTCTGCTGGAGAGACACAACATCTATGTACAGGCGATAAACTACCCGACTGTGCCACGTGGAGAAGAGCTGCTGCGTTTGGCACCATCCCCTTTCCACAACCCCGTCATGATGGATTACTTTGTGGAGAAATTGGTGGATGTATGGCAGGAAGTTGGACTGCCACTCAATGCCCCTGCAACAGCCTCCTGCACTTTCTGTGACCGTCCCCTCTACTTTGACCTCATGAGCGAGTGGGAGAAAAGTTACTTTGGCAATATGGAACCAAGATATATTACAGTTGCAGCacaataagaaaaatgaaagggAAGAGAGATGGAAAGCAACATTCAGTATAatcagctgaaaagatcattattaaagaaaaaaatcataactgCTGAGATATCTTCTTTTACACTGTCATACATATTGCTGCCTGCTGCAGTTACGTCATTAGTACTGGCTTTGGTGCTGTTGGATTATATACCTTTTCATGGAATATTAGGTCTGTGTCCCCTCTGCATTATTAAAAACCTGCACATGGGCACTTTTAATggaaactatttaaaaatatttaaatactttaattttttattatttatattatattttattcacaatcCATATCTATGTCTCTTATGCATTAGACTTGAGTTCGAATGCATTAGACTTGAGTTTGACTTGAGTTTGAAAAGCTTTATCCCAAAGTCTTGACTACAGCCTAAATAGGCAACAACAAACATGGTCTTACACTTGCTAATTTCACAACACCATGTTCTAAAAAAGATATGAAAGTTAAGGTTATTGTTAGGGGCAGGGTTGGGATTCGTACCTTTTCTTACAACTCCAAATCAAATTGGTGTATTTAATTGGAATTTACACTGCACATTAACTTACACTAGTTTGCTAGGTAACCGGCTAATCATTATTTTCTCTAATTTTCCAaattacatgtacatttttagGCTTCAGAGTCCTTTTAAACAGCAGAACCTTTGTGATAGCAGCTGAGAAATACAGCCCACCTCAGCTGAAGCTTAAACACTGTGATGCACCTGTTATCTTATTAAATTTCCTATTTGGGTTTTGCATTTAGGCAGGAGTGTGCATAATGATCCCAGGAATATACAGAATCAATCTACTTTGCTTCTtcagatcattttattttcatgaggTCAATGTTttatgagaaataaaatcaaacaacacTCTTGAA

Function

symbol description
alas2 Predicted to enable 5-aminolevulinate synthase activity. Acts upstream of or within heme biosynthetic process; hemoglobin biosynthetic process; and hemopoiesis. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Is expressed in erythroid progenitor cell; hematopoietic system; mesoderm; and pronephric duct. Used to study sideroblastic anemia. Human ortholog(s) of this gene implicated in cutaneous porphyria; erythropoietic protoporphyria; hemochromatosis; sideroblastic anemia; and sideroblastic anemia 1. Orthologous to human ALAS2 (5'-aminolevulinate synthase 2).

NR:

description
5-aminolevulinate synthase, erythroid-specific, mitochondrial-like

GO:

id name namespace
GO:0030218 erythrocyte differentiation biological_process
GO:0042541 hemoglobin biosynthetic process biological_process
GO:0006782 protoporphyrinogen IX biosynthetic process biological_process
GO:0035162 embryonic hemopoiesis biological_process
GO:0001666 response to hypoxia biological_process
GO:0005743 mitochondrial inner membrane cellular_component
GO:0005759 mitochondrial matrix cellular_component
GO:0003870 5-aminolevulinate synthase activity molecular_function
GO:0030170 pyridoxal phosphate binding molecular_function

KEGG:

id description
K00643 E2.3.1.37, ALAS; 5-aminolevulinate synthase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026923200.2 True 2825 mRNA 0.46 11 11841583 11849987
XM_034306542.1 False 2535 mRNA 0.44 10 11844351 11849987

Neighbor

gene id symbol gene type direction distance location
itpr3 itpr3,LOC108441646,LOC106572092,LOC107731245 coding upstream 1699 11803048 ~ 11839884 (+)
cry3a cry1ba,LOC108265656,LOC108441644,LOC107668038 coding upstream 50410 11766040 ~ 11791173 (+)
col2a1a col2a1a,LOC108265655,LOC107668081,LOC107585898,LOC107731244 coding upstream 77992 11738339 ~ 11763591 (+)
spryd4 spryd4 coding upstream 124909 11714943 ~ 11716674 (+)
magoh mgn,magoh,LOC106560432,LOC107387361,LOC101074452,LOC107731141,LOC107549138 coding upstream 142215 11696883 ~ 11699368 (+)
LOC113530463 LOC108266055 coding downstream 4180 11854167 ~ 11857253 (+)
fhad1 LOC108266054 coding downstream 8481 11858468 ~ 11861880 (+)
LOC113530451 LOC108266054 coding downstream 11470 11861457 ~ 11876088 (+)
efhd2 efhd2,LOC107711975,LOC107591793 coding downstream 32259 11882246 ~ 11904257 (+)
taf10 taf10,LOC106572212,LOC107679390,LOC107711978,LOC107591795,LOC107550511,LOC107707678 coding downstream 56761 11906748 ~ 11910004 (+)
G131061 NA non-coding upstream 123698 11716832 ~ 11717885 (+)
G130960 NA non-coding upstream 289552 11548962 ~ 11552031 (+)
LOC117597850 NA non-coding upstream 482203 11355449 ~ 11359380 (+)
LOC113527270 NA non-coding upstream 893237 10944657 ~ 10948346 (+)
G130618 NA non-coding upstream 924958 10916337 ~ 10916625 (+)
G131279 NA non-coding downstream 367017 12217004 ~ 12217214 (+)
G131282 NA non-coding downstream 376165 12226152 ~ 12226362 (+)
LOC117597859 NA non-coding downstream 669907 12519894 ~ 12533258 (+)
G131606 NA non-coding downstream 840180 12690167 ~ 12712485 (+)
LOC117597872 NA non-coding downstream 850725 12700712 ~ 12701501 (+)
porcn porcn,LOC108265120,LOC108441640,LOC107668076,LOC107585894,LOC107745789 other upstream 127551 11705547 ~ 11714032 (+)
uck2a uck2,uck2a,LOC108441637,LOC107731246,LOC107668082,LOC107745792,LOC107585889,LOC106584056,LOC107549113,LOC107695269 other upstream 144792 11677511 ~ 11696791 (+)
LOC113530800 LOC108266038 other upstream 207739 11622302 ~ 11633844 (+)
mrpl55 mrpl55 other upstream 967457 10870119 ~ 10874126 (+)
abl2 abl2,LOC107657876,LOC107699422,LOC107599009,LOC107758002,LOC107707589,LOC107603207 other upstream 1100158 10706719 ~ 10741425 (+)
foxp3a LOC108265789 other downstream 129199 11979186 ~ 11995852 (+)
kcnq2a LOC108265949,LOC108442249,LOC107668096,LOC107550457,LOC107711924,LOC107731192,LOC107679259 other downstream 346606 12196593 ~ 12230001 (+)
rbm15 rbm15,LOC107731203 other downstream 749711 12599698 ~ 12604705 (+)
LOC113527348 LOC108266008,LOC108437580,LOC107731173,LOC107549994,LOC107745767 other downstream 1855179 13705166 ~ 13791317 (+)
dock8 dock8 other downstream 2040417 13890404 ~ 13948808 (+)

Expression


Co-expression Network