b2ml (b2m)


Basic Information

Item Value
gene id b2ml
gene name b2m
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047602.1
NCBI id CM018548.1
chromosome length 30442583
location 25662794 ~ 25665298 (+)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026925487.2
ctttcatttcagtttcaggcGACTGTTGAGGAGGAGAGAGCAGTGCAGGTGTTCCGGAAAAGCTGTCCAGGTTCTGCGGcgaagattattttatttttgtcagatttttatTCGACTGTTTGTTCGGAAAGATGAAGGTGCTGCTTTCTTTCGTCGTGCTCGCTGTTTTCAGCGCAAGTGCCTTTGCTAAGGAGTCTTCACCAAAGATCCAGGTTTACAGCCGTAACCCTGGTGAGTATGGCAAAGAGAACACACTGATCTGCCACGTGAGTGACTTCCACCCCCCAGACATTGAAATCAAACTGCTGAAGAATGGTGTGGAGATTCCAAACGCCAAGCAGACTGACCTGGCCTTTGAGCAGGGCTGGAAGTTTCATCTGACTAAGAGCGTCGCCTTCACACCCACCAGCGGTGACACATTCTCCTGCAAGGTCAGACACCTGAGCAGTGAGAAGACCTTCACCTGGGAGCCAGACATGTAAATCTCCTGGGCTTCATTCCATCTGGCCGCTCTTTATTTCCACACTTGCAGTAATGATACCACTTTCTGACCATCAATTCACCTCTCATTAGTAAATTGAACTTCATTGTATATCTGACATAGGGCTGGGCGatacaataaaaatgtctttgtgatATTTGAAAAACACCTTCCAGGTATACAATATAGAACAAGGCGTTTAGTTTCACTTGTTGggttttgctaacaaaaaacccaaaatattGCTACTATTAATGAAAAAGCATGAATTATTTGATTCAGCATTCACTAAAGATTCAGATATTTAAGAAGGTAATCGgtggaaacatttaaaaaattagttATGTGTTACAATGAGCCACAGTGGCAttataaaagcagaaaaactcagaaaacaacaacaacaaaaaatatagtCCTATCGCCCAGCCCTGTGTGTCATCTACGCTTTAGTTAATCAAGCAATATCTCTacagtttaaaatgtaaaaactagAACTTTATGCGGTTTGGATAACTAAATTCCTAATGTGgggaatgtgttttttttttttttttaaagcttcatAATTTTTGTCtatcttcttttatttctgattcATCATGGTGTGTAAAGTTTGATAAATAACTTTTGTTATGctcctttaaaatgttttaaataattgacATAAGACTTCTAAATATTGGTTTTCTTGAGGTTTTCAATCACTGTTAATTGTAATGTAAAAAGAAGTAATAAAATTCTGTCCCCCTCCCCAA

Function

symbol description
b2m Predicted to enable MHC class II protein complex binding activity. Predicted to be involved in antigen processing and presentation of exogenous peptide antigen via MHC class II; peptide antigen assembly with MHC class II protein complex; and positive regulation of T cell activation. Predicted to act upstream of or within several processes, including MyD88-dependent toll-like receptor signaling pathway; negative regulation of innate immune response; and negative regulation of toll-like receptor signaling pathway. Predicted to be located in extracellular region and membrane. Predicted to be integral component of membrane. Predicted to be part of MHC class II protein complex. Is expressed in several structures, including eye; heart; integument; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in arthritis; familial visceral amyloidosis; immunodeficiency 43; and inflammatory bowel disease. Orthologous to human B2M (beta-2-microglobulin).

NR:

description
beta-2-microglobulin precursor

GO:

id name namespace
GO:0006955 immune response biological_process
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I biological_process
GO:0005576 extracellular region cellular_component
GO:0042612 MHC class I protein complex cellular_component

KEGG:

id description
K08055 B2M; beta-2-microglobulin

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026925487.2 True 1239 mRNA 0.38 4 25662794 25665298

Neighbor

gene id symbol gene type direction distance location
bin3 bin3,LOC107665194,LOC107678406,LOC107710841 coding upstream 55930 25563821 ~ 25606864 (+)
LOC113533497 pebp4 coding upstream 119206 25453639 ~ 25543588 (+)
LOC113533297 rhobtb2 coding upstream 215920 25435201 ~ 25446874 (+)
slc25a37 slc25a37,LOC107559458,LOC107710846,LOC107747712 coding upstream 371219 25276381 ~ 25291575 (+)
trnae-cuc_21 NA coding upstream 391114 25271609 ~ 25271680 (+)
ubl4a ubl4a,zgc:56596,LOC107665196,LOC107553161,LOC107562643 coding downstream 1627 25666925 ~ 25671900 (+)
si:dkey-32e23.4 si:dkey-32e23.4,LOC108426682,LOC108265374,LOC103036512,LOC107710834,LOC107562650,LOC107665195,LOC107678420 coding downstream 20907 25686205 ~ 25703125 (+)
disp3 disp3,LOC107710822,LOC107553125,LOC107678473,LOC107562651 coding downstream 97667 25762965 ~ 25804442 (+)
LOC113537824 NA coding downstream 252449 25917747 ~ 25919263 (+)
LOC117595683 NA coding downstream 273348 25938646 ~ 25940631 (+)
G138961 NA non-coding upstream 211217 25448615 ~ 25451577 (+)
LOC117597843 LOC108261789,LOC108265915 non-coding upstream 234606 25421054 ~ 25428188 (+)
LOC113533374 NA non-coding upstream 329181 25309905 ~ 25333613 (+)
G138907 NA non-coding upstream 377846 25277297 ~ 25284948 (+)
LOC113533216 NA non-coding upstream 813250 24848068 ~ 24849544 (+)
G139166 NA non-coding downstream 7220 25672518 ~ 25683091 (+)
G139172 NA non-coding downstream 144877 25810175 ~ 25815041 (+)
LOC113546140 NA non-coding downstream 283551 25948849 ~ 25950449 (+)
G139235 LOC108265343 non-coding downstream 367296 26032594 ~ 26036133 (+)
G139551 NA non-coding downstream 847594 26512892 ~ 26519482 (+)
egr3 egr3 other upstream 104063 25551894 ~ 25558731 (+)
LOC113533115 gnrh1 other upstream 528536 25132741 ~ 25134258 (+)
fkbp1aa fkb1b,fkbp1aa,fkbp1a,fkbp1ab,LOC103030299,LOC107553142,LOC107574256,LOC107752559,LOC107707744 other upstream 1649013 24011582 ~ 24013781 (+)
praf2 praf2,LOC107756831,LOC107702816,LOC107691574,LOC107565129 other upstream 1768069 23890416 ~ 23894725 (+)
G138010 iqsec2,LOC108265842,LOC108442091 other upstream 1905680 23750417 ~ 23757114 (+)
LOC117597866 NA other downstream 244277 25909575 ~ 25916807 (+)
car15 LOC108264895 other downstream 734893 26400191 ~ 26462321 (+)
LOC117597788 NA other downstream 897522 26562820 ~ 26567932 (+)
rimbp2 rimbp2,LOC108414005 other downstream 960755 26626053 ~ 26729946 (+)
fam160b2 LOC108265858 other downstream 1517723 27183021 ~ 27261741 (+)

Expression


Co-expression Network