chrna7a (chrna7,LOC108270560,LOC108434558,LOC107748270,LOC107679711,LOC107686877)


Basic Information

Item Value
gene id chrna7a
gene name chrna7,LOC108270560,LOC108434558,LOC107748270,LOC107679711,LOC107686877
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047605.1
NCBI id CM018551.1
chromosome length 26640196
location 5199143 ~ 5220239 (-)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026930897.2
CATCCCTGAAGGAGGAGCGGGTCTGACTCGGGATATTTCCCCAGTCCTGagttctttcttcttttccaggCTAAAATGGGAATTTGCGGTTTTGCGCTTTGTTTAGCAATCACTACATGTTTGTGGAGGGCATCCATTCAAGGAGAGCATCAGAGGAGGCTGTATCGAGACCTCATGAAAGATTACAACCCTCTAGAGAGACCTGTGTTTAATGACACCCAGTCACTGACCGTAAACTTCAGCTTCAGCTTGATGCAGATCATGGACGTGGATGAGAAGAATCAAGTTCTCACAACGAACATATGGCTACAGCTGTACTGGTTCGATCATTACCTTAAATGGAATGTCTCCGAATATCCCGGTGTGACGAGCGTCCGATTTCCTGATAGCCAGATTTGGAAGCCTGACATTTTGCTTTATAACAGTGCTGATGAGCGATTTGATGCCACCTTTCACACCAACGTGCTAGTCAGCTCCAACGGCGCCTGCCAATACTTACCACCAGGTATCTTTAAAAGCACATGTCACATCGACGTGCGGTGGTTTCCCTTCGATGTTCAGCGGTGTGACCTGAAGTTCGGCTCATGGACGTACGGTGGCTGGTCGCTGGACCTGCAGATGATTGAGGCTGATATCACAGGCTATATAGCCAATGGAGAATGGGACCTTGTAGAGGTTCCAGGTCACAGGAATGAAAGGTTCTATGACTGCTGTAAAGAACCGTACCCGGATGTGACGTTCACAGTGGTGATGCGGAGACGGACGCTGTACTACGGTCTAAACCTGCTCATTCCATGTGTCCTCATCTCCACACTGGCTCTGCTCGTCTTCCTCCTGCCTGCAGATTCAGGCGAGAAGATCTCCCTCGGAATCACAGTTTTGCTCTCACTGACTGTCTTCATGCTCCTGGTTGCCGAAATCATGCCTGCGACGTCAGACTCAGTGCCTTTAATCGCTCAGTATTTTGCCACTACCATGGTTATCGTCGGGTTGTCGGTGATAGCCACAGTTTGGGTCCTACAGTATCACTACCATGATCCCGATGGAGGAAAAATGCCAAGATGGACACGTGTGGTGCTGGTGAACTGGTGTGCATGGTTCTTGCGGATGAAAAGGCCGGGCGAGGAGCGAGTGCGCTCAGCGTGCCACGACAAGCGTCCACGCAGCAGCGTCTCCAGCGTGGAACCGACCAATGGAAACGTTCTCTACATGGGCCTGCGTGGTATGGAGAGCCTGCCCTGTGCCACGTCGCCCGACTCAGGGGTGGTGTGTGCCCGTCTCATGGGGACGTCCGAAGAGGCTCCGTCAGTGAGCAGCGGGCAGGGAGACACGGAGCTGTCCAAGATCCTGGACGAGGTGCGCTATATTGCCAAGAGGTTCCACGACCAGGATGAAGAGGAGTCTTTGTGTAGCGAGTGGAAGTTTGCTGCCTCGGTTATCGACCGCTTGTGTCTCATGGCCTTTTCCATGTTCACTGTCCTCTGCACCATCGGCATCCTCATGTCAGCTCCTAATTTCGTCGAAGCCATTTCCAAAGACTTCTTCACTTAAACGTTGTGTGTGTAGCTTTTCCTGCAGCTTTTCAGAGTTTACTGCAGAGTCAGAGGTGTAGTTCagattgaaataaaatgaaatgtacacattttttccttaaataaatagaaactaAATCAATTAGGACATAGATTCTCGATTCTCAATTTGGTCTCCAAGACAAAACTAAATAAGCAAACTTTAGACCTCAATCtttgtgtaaatttcattttttttagctgaactGTTTAAAGCAAGCGAGTAATAAAGGGTAGAAATGACTTGCAGTACTGACAGTTGTCTGGTGTTTTGTAGTTAAAATACAATTCATTTCTGTTATTACTCTCAGTTTATAAGTGAAAGTGATCTAAATGTGCAGCATATTCATAACTATTcatataatcaattataatcaTAATAGCCTTCACACAGTAGCTGGACTGTAACCTGATACACACTGGTAACgctctgcttttgtttttttttattttatttctcttcatttaCATGACAAAGTAAAGAAATCAGCAATATTTCAAAGTATTTTCATGTATCAGAGTGAGCACTGTGACCTTGTATCTGGTGGGGATGATATGTCCAGTTTCATACGTTTTCAACCTTAACGCCAGCGAACACTGCTATAAGCAGCTATAAGTCATCATTAAGCTGCATAGGTCTgagattcctttttttttaattttcttcaaaGTTGCCTTTATGATGTAGAGTGacaaataaagatatttttctATATCTTAGAAAAATAAA

Function

symbol description
chrna7 Enables several functions, including acetylcholine binding activity; amyloid-beta binding activity; and postsynaptic neurotransmitter receptor activity. Involved in several processes, including negative regulation of amyloid-beta formation; positive regulation of MAPK cascade; and positive regulation of angiogenesis. Acts upstream of or within negative regulation of tumor necrosis factor production. Located in plasma membrane. Part of acetylcholine-gated channel complex. Implicated in schizophrenia. Biomarker of Alzheimer's disease and Lewy body dementia.

NR:

description
PREDICTED: neuronal acetylcholine receptor subunit alpha-7-like

GO:

id name namespace
GO:0006811 ion transport biological_process
GO:0045211 postsynaptic membrane cellular_component
GO:0005892 acetylcholine-gated channel complex cellular_component
GO:0030054 cell junction cellular_component
GO:0015464 acetylcholine receptor activity molecular_function

KEGG:

id description
K04809 CHRNA7; nicotinic acetylcholine receptor alpha-7

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026930897.2 True 2301 mRNA 0.45 10 5199143 5220239

Neighbor

gene id symbol gene type direction distance location
znf609b LOC108271255,LOC108434576,LOC107679726,LOC107748266,LOC107738902 coding downstream 65593 5081652 ~ 5133550 (-)
gramd2aa gramd2,LOC108270961,LOC107748265,LOC106562775 coding downstream 124841 5047351 ~ 5074302 (-)
myo9aa myo9a coding downstream 166249 4923363 ~ 5032894 (-)
scamp2l LOC108271388 coding downstream 279884 4907933 ~ 4919259 (-)
neo1a LOC108271025,LOC108434571 coding downstream 337515 4738083 ~ 4861628 (-)
LOC113536575 adamts7 coding upstream 9087 5229326 ~ 5302351 (-)
trnai-uau_1 NA coding upstream 70263 5290502 ~ 5290594 (-)
trnai-uau_2 NA coding upstream 93923 5314162 ~ 5314254 (-)
cdhr5a LOC108270552,LOC108412775 coding upstream 98113 5318352 ~ 5325458 (-)
sirt3 sirt3,LOC107663051 coding upstream 140179 5360418 ~ 5366235 (-)
G176336 NA non-coding downstream 85875 5110114 ~ 5113268 (-)
G176029 NA non-coding downstream 352002 4840748 ~ 4847141 (-)
G176028 NA non-coding downstream 358450 4839988 ~ 4840693 (-)
G176015 NA non-coding downstream 462727 4732382 ~ 4736416 (-)
G175967 NA non-coding downstream 566358 4630348 ~ 4632785 (-)
G176354 NA non-coding upstream 84375 5304614 ~ 5407099 (-)
G176556 NA non-coding upstream 411587 5631826 ~ 5715020 (-)
G176817 NA non-coding upstream 862589 6082828 ~ 6167802 (-)
G176816 LOC108271104 non-coding upstream 951959 6172198 ~ 6176354 (-)
G176832 NA non-coding upstream 964096 6184335 ~ 6188288 (-)
trip4 trip4 other downstream 2325 5139610 ~ 5196818 (-)
G176307 NA other downstream 118248 5079817 ~ 5080895 (-)
lto1 oraov1 other downstream 694814 4498946 ~ 4504329 (-)
bola3 bola3,LOC107686851,LOC107727091 other downstream 1202690 3992726 ~ 3996453 (-)
mical2a mical2 other downstream 1289250 3851847 ~ 3909893 (-)
LOC113536561 srsf7,LOC107665899,LOC107693014 other upstream 476141 5696380 ~ 5708304 (-)
LOC113536608 LOC108270551 other upstream 1636516 6856755 ~ 6861348 (-)
si:dkey-56d12.4 LOC108270721 other upstream 2260183 7480422 ~ 7484117 (-)
si:ch1073-365p7.2 NA other upstream 2360195 7580434 ~ 7588815 (-)
igf1rb LOC108271091 other upstream 2455677 7675916 ~ 7764430 (-)

Expression


Co-expression Network