prkg1b (prkg1,prkg1b,LOC107654050,LOC107695529,LOC106589397)



Basic Information


Item Value
gene id prkg1b
gene name prkg1,prkg1b,LOC107654050,LOC107695529,LOC106589397
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information


Item Value
chromosome id NC_047606.1
NCBI id CM018552.1
chromosome length 26563515
location 6862071 ~ 7015737 (+)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence


>XM_026915239.2
TGTTTCGGCATTCCGGGAGCGCTCGCGCGTCTGAGCGGTTCTGTAAGACCATGTGCGTGAGAAGTGCGTGagaaaagaacacaaacaacttttgtgtgtgtgtgtgtgtgtgtgtgtgtgtatatgtgtgcgtgCGGTGTTTTTTTTCCGAGTGCGATGCATCGGGAATTCGTATGCGCGCGTGACTTTTTGCGTTGATTTCCTCAGTAGTGATCACGTGCGCGCGGCTTTGTGACAGCTTGACAGCTTTTGTTGCGCTTGCCACAGTCAGCTGGAAGCTCGGAGAGCATCAGGGGAGCATGGGCACCCTGCGCGACCTGCAGTACGCCTTGCAGGAGAAGATCGAGGAGCTGAGGCAGAGGGACGCGCTGATCGACGAGCTGGAGCTCGAGCTGGACCAGAAAGATGAGCTGATCCAGAAACTACAGACTGAGCTGGATAAGTACCGCTCTGTGATCAGACCAGCCACACAGCAGGTCCAGCAGAAACAGAACGAGCTGCAGGAGCAGCAGAGGACCAAACGGCAAGCCATCTCAGCTGAACCAACCGCCCTGGACATCCAGGATCTCAGCCAAGTCACCCTGCCCTTCTACCCCAAGAGCCCAGAGTCCAAGGAACTCATCAAGGAGGCCATTCTAGACAATGATTTCATGAAGAACCTGGAGCTCTCACAGATCCAGGAGATAGTGGACTGCATGTACCCGGTGGAATATGACAAAGAGAGCTGCATTATTAAAGAGGGCGACGTGGGCTCACTCGTCTATGTTATGGAAGATGGCAAGGTGGAGGTGACCAAGGAGGGCATGAAGCTGTGCACCATGGGACCAGGCAAAGTGTTCGGCGAGCTGGCCATCCTCTACAACTGCACACGCACCGCCACTGTTCAGACTCTCACTAATGTGAAGCTATGGGCTATTGACCGGCAGTGTTTCCAGACCATCATGATGAGGACAGGACTCATCAAGCATGCTGAGTACATGGAGTTCCTCAAGAGTGTTCCCACATTCCAAGGCCTTCCAGAAGAAATACTCAGCAAACTCGCAGATGTGCTGGAAGAGACTCACTATAGTGATGGAGAATACATAATCAGACAGGGCGCTAGAGGAGACACCTtcttcatcatcagtaaagGAAAGGTGAATGTTACCCGAGAGGATTCGCCCAATGACACTGTTCATCTGCGTGGCTTGGGGAAAGGGGACTGGTTTGGAGAAAAAGCTCTTCAAGGAGAAGACATTAGGACGGCCAATGTCATTGCTGCTGAGGCTGTCACCTGCCTGGTCATCGACAGAGATTCATTTAAGCATTTGATTGGAGGTCTGGATGACGTCTCGAACAAAGGCTATGAGGATGCTGGAGCCAAAGCAAAataCGAGGCAGAAAACGCCTTCTTCTCCAACCTGAAGCTGGTGGACTTCAACATCATCGATACCTTAGGGGTGGGAGGATTCGGACGAGTCGAGCTGGTACAGCTCAAAAGTGAGGAGACCAAAACGTTTGCCATGAAGATTCTGAAAAAGCGCCACATTGTGGACACACGGCAACAGGAACACATCCGCTCCGAGAAACACATCATGCAGGAAGCCCACTCAGACTTTATAGTGAGATTATACAGGACATTTAAAGACAGCAAATATCTGTATATGCTGATGGAAGCCTGTTTGGGAGGAGAACTATGGACCATTCTTAGAGATAGAGGATCTTTTGAAGACTCCACAACACGCTTTTACACAGCCTGTGTAGTGGAAGCCTTCGCTTATTTGCATTCCAAAGGGATAATTTACCGAGATCTCAAGCCAGAAAACCTCATCCTAGATCACAGAGGCTACGCCAAGCTGGTGGACTTTGGCTTTGCCAAAAAGATTGGATTTGGGAAGAAGACATGGACTTTCTGTGGAACACCGGAATATGTAGCCCCAGAAATTATTCTCAACAAAGGCCACGACATCTCAGCAGATTACTGGTCACTTGGTATCCTTATGTATGAACTCCTGACTGgcagCCCACCATTCTCAGGGCCAGATCCAATGAAGACATACAATATAATCTTAAGAGGTATTGATATGATTGAATTTCCAAAGAAGATCACCAAAAATGCTGCCAATCTAATAAAGAAGCTATGCAGGGACAATCCATCTGAGAGACTAGGGAACTTGAAAAATGGGGTGAAGGATATCCAAAAGCACAAATGGTTTGAAGGCTTTAACTGGGAAGGGTTGCGCAAAGGGACTCTCACCCCTCCTATTATCCCTGAAGTGTCATCACCCACCGACACCAGTAACTTTGACAGTTTCCCCGAGGACAACGAGGACCCGCCACCCGACGACAACTCAGGCTGGGACACGGATTTCTGATCCGATTGGCCTGTCTGAATGTCAGTCAGGACCTTCAGGACATGGTTGTGTTGAGTGACTGCTGCTCAAGGAggcaaacttaaaaaaaaaaaagaa
>XM_026915240.2
GATCTGAagactctgtctctctctctttctctctctctctctctctctctctctctctctcgcgcgcaCACGCACCACCGGCACCGGCACCGGCTTTTCTTCGTCGCGAGCGCCAAAGTTCCAAGATGAGCGATTTGGACGAGGATCTGGCCAAGCTGCTTGTGATGAAGGATGAAAGGATTAAGGAGATGGAAAGACGCCTCggagagaaggaagaggagaTCCAGGAGCTGAAGAGGAAGCTGCACAAATGTCAGTCGGTGTTACCGAGCGCGCAGATGATCGGACCGAGGACCAGGCGCGCGCAGGGCATCTCAGCAGAGCCGCAAAGCTTCACCTCCTTCACCGAGCTCACCGCAGAGGCTTTCCGCAAAATCCCCAAGTCTGACAGGTCCAAGGAACTCATCAAGGAGGCCATTCTAGACAATGATTTCATGAAGAACCTGGAGCTCTCACAGATCCAGGAGATAGTGGACTGCATGTACCCGGTGGAATATGACAAAGAGAGCTGCATTATTAAAGAGGGCGACGTGGGCTCACTCGTCTATGTTATGGAAGATGGCAAGGTGGAGGTGACCAAGGAGGGCATGAAGCTGTGCACCATGGGACCAGGCAAAGTGTTCGGCGAGCTGGCCATCCTCTACAACTGCACACGCACCGCCACTGTTCAGACTCTCACTAATGTGAAGCTATGGGCTATTGACCGGCAGTGTTTCCAGACCATCATGATGAGGACAGGACTCATCAAGCATGCTGAGTACATGGAGTTCCTCAAGAGTGTTCCCACATTCCAAGGCCTTCCAGAAGAAATACTCAGCAAACTCGCAGATGTGCTGGAAGAGACTCACTATAGTGATGGAGAATACATAATCAGACAGGGCGCTAGAGGAGACACCTtcttcatcatcagtaaagGAAAGGTGAATGTTACCCGAGAGGATTCGCCCAATGACACTGTTCATCTGCGTGGCTTGGGGAAAGGGGACTGGTTTGGAGAAAAAGCTCTTCAAGGAGAAGACATTAGGACGGCCAATGTCATTGCTGCTGAGGCTGTCACCTGCCTGGTCATCGACAGAGATTCATTTAAGCATTTGATTGGAGGTCTGGATGACGTCTCGAACAAAGGCTATGAGGATGCTGGAGCCAAAGCAAAataCGAGGCAGAAAACGCCTTCTTCTCCAACCTGAAGCTGGTGGACTTCAACATCATCGATACCTTAGGGGTGGGAGGATTCGGACGAGTCGAGCTGGTACAGCTCAAAAGTGAGGAGACCAAAACGTTTGCCATGAAGATTCTGAAAAAGCGCCACATTGTGGACACACGGCAACAGGAACACATCCGCTCCGAGAAACACATCATGCAGGAAGCCCACTCAGACTTTATAGTGAGATTATACAGGACATTTAAAGACAGCAAATATCTGTATATGCTGATGGAAGCCTGTTTGGGAGGAGAACTATGGACCATTCTTAGAGATAGAGGATCTTTTGAAGACTCCACAACACGCTTTTACACAGCCTGTGTAGTGGAAGCCTTCGCTTATTTGCATTCCAAAGGGATAATTTACCGAGATCTCAAGCCAGAAAACCTCATCCTAGATCACAGAGGCTACGCCAAGCTGGTGGACTTTGGCTTTGCCAAAAAGATTGGATTTGGGAAGAAGACATGGACTTTCTGTGGAACACCGGAATATGTAGCCCCAGAAATTATTCTCAACAAAGGCCACGACATCTCAGCAGATTACTGGTCACTTGGTATCCTTATGTATGAACTCCTGACTGgcagCCCACCATTCTCAGGGCCAGATCCAATGAAGACATACAATATAATCTTAAGAGGTATTGATATGATTGAATTTCCAAAGAAGATCACCAAAAATGCTGCCAATCTAATAAAGAAGCTATGCAGGGACAATCCATCTGAGAGACTAGGGAACTTGAAAAATGGGGTGAAGGATATCCAAAAGCACAAATGGTTTGAAGGCTTTAACTGGGAAGGGTTGCGCAAAGGGACTCTCACCCCTCCTATTATCCCTGAAGTGTCATCACCCACCGACACCAGTAACTTTGACAGTTTCCCCGAGGACAACGAGGACCCGCCACCCGACGACAACTCAGGCTGGGACACGGATTTCTGATCCGATTGGCCTGTCTGAATGTCAGTCAGGACCTTCAGGACATGGTTGTGTTGAGTGACTGCTGCTCAAGGAggcaaacttaaaaaaaaaaaagaa

Function


symbol description
prkg1b Predicted to enable ATP binding activity; cGMP binding activity; and cGMP-dependent protein kinase activity. Predicted to act upstream of or within protein phosphorylation. Is expressed in several structures, including female organism; heart; integument; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in thoracic aortic aneurysm. Orthologous to human PRKG1 (protein kinase cGMP-dependent 1).
prkg1 Enables cGMP-dependent protein kinase activity; calcium channel regulator activity; and identical protein binding activity. Involved in several processes, including negative regulation of platelet aggregation; negative regulation of vascular associated smooth muscle cell migration; and negative regulation of vascular associated smooth muscle cell proliferation. Located in cytoplasm and plasma membrane. Implicated in thoracic aortic aneurysm.

NR:

description
PREDICTED: cGMP-dependent protein kinase 1 isoform X1

GO: NA

KEGG:

id description
K07376 PRKG1; cGMP-dependent protein kinase 1

RNA


RNA id representative length rna type GC content exon number start site end site
XM_026915239.2 True 2450 mRNA 0.49 18 6869665 7015737
XM_026915240.2 False 2234 mRNA 0.49 18 6862071 7015737

Neighbor


gene id symbol gene type direction distance location
sgms1 sgms1 coding upstream 46626 6796007 ~ 6815445 (+)
trnap-cgg_7 NA coding upstream 72126 6789874 ~ 6789945 (+)
trnap-ugg_20 NA coding upstream 73305 6788695 ~ 6788766 (+)
trnap-agg_8 NA coding upstream 74469 6787531 ~ 6787602 (+)
trnap-cgg_6 NA coding upstream 75648 6786352 ~ 6786423 (+)
dkk1b dkk1 coding downstream 6186 7021923 ~ 7023638 (+)
bicc1b bicc1,bicc1b,LOC107653928,LOC107695510 coding downstream 431781 7447518 ~ 7514069 (+)
phyhiplb phyhipl,phyhiplb,LOC107695536,LOC107727060,LOC107746456 coding downstream 510851 7526588 ~ 7547407 (+)
rhobtb1 rhobtb1,LOC107654062,LOC107727061,LOC107745661 coding downstream 756607 7772344 ~ 7795900 (+)
cabcoco1 c13h10orf107 coding downstream 796713 7812450 ~ 7838426 (+)
G192043 NA non-coding upstream 76475 6778164 ~ 6785596 (+)
G192029 NA non-coding upstream 165101 6696732 ~ 6696970 (+)
G191868 NA non-coding upstream 388605 6463389 ~ 6473466 (+)
G191866 NA non-coding upstream 401057 6460811 ~ 6461014 (+)
G191719 NA non-coding upstream 591186 6268524 ~ 6270885 (+)
G192394 NA non-coding downstream 383606 7399343 ~ 7399628 (+)
G192422 NA non-coding downstream 458700 7474437 ~ 7475004 (+)
G192591 NA non-coding downstream 923304 7939041 ~ 7939584 (+)
G192650 NA non-coding downstream 1053406 8069143 ~ 8071592 (+)
G192644 NA non-coding downstream 1111036 8126773 ~ 8141060 (+)
asah2 asah2,LOC107598643 other upstream 25688 6822740 ~ 6836383 (+)
LOC113527389 NA other upstream 133680 6725321 ~ 6728391 (+)
G191581 NA other upstream 878834 5969743 ~ 5983237 (+)
LOC113527671 LOC108441166,LOC108273636 other upstream 1121166 5730154 ~ 5740905 (+)
LOC113527051 LOC108274342,LOC108274341,LOC108425932 other upstream 1521508 5330042 ~ 5340563 (+)
tfam tfam other downstream 412808 7428545 ~ 7436372 (+)
G192484 ank3 other downstream 590244 7605981 ~ 7628111 (+)
LOC113527534 dnah9 other downstream 2252756 9268493 ~ 9357961 (+)
G193383 LOC108273473 other downstream 2352506 9368243 ~ 9369915 (+)
trnaq-cug_13 NA other downstream 2496432 9512169 ~ 9512401 (+)

Expression



Co-expression Network