mtr (mtr)



Basic Information


Item Value
gene id mtr
gene name mtr
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information


Item Value
chromosome id NC_047606.1
NCBI id CM018552.1
chromosome length 26563515
location 20290593 ~ 20316556 (+)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence


>XM_026915459.2
TGCGCTGTTCACGCATGCGCAGAAACCAGTTAGGGCGCACGCGTCGCGTCGAGCATGTGCAGTAGACAGTGTTTGATTCGCTCACGCGAGAGAGCAGTTTTAACTGGGGTTTATGGGCAGAATTGCGGGGCAAACTAAAGGGGATGTTCATGTTTTAAGGGTGTAAAAGTCTTCGCTGAAGCTGTCCAGGTTGTTTTGGAACACGGTTGAGAATATACGTTTTAAAATGGGGCCGACGGTTCAGTATGAGACAGAAACAGGGGCTGGAGCAGCTTCTCTAGAGGCTGAGCTCAGAGAGACGCTGCAGAAGAGGATCATGGTCCTGGATGGTGGAATGGGTACCATGATTCAGCAGAGGAATCTACAGGAAGACGACTTCCGGGGTCAGGAGTTCAATGATCACCCACGAAGCCTGAAAGGCAACAATGACCTGCTGAGCATCACCAAGCCTGAGGTCATCTATGCTATCCACAAGGAGTACCTGCTTGCTGGAGCAGATATCATTGAGACGAACACATTCAGCAGTACACGGATTGCTCAGGCGGATTACGGGCTCGAGGAGCTGGCCTATCGGCTTAACAAGGCGTCGGCAGAATTAGCCCGGAAAGCCGCTGATGAAGTTTCTGCTCAGACAGGTGTTAAACGGTATGTGGCTGGAGCTGTAGGGCCGACCAACAGAACTCTGTCTGTGTCACCATCTGTGGAAAGACCAGACTTCAGAAACATCACATTTGATGAACTGGTTGAGGCGTACTCGGAGCAGGTTCAAGGGCTGCTGGATGGAGGATGTGATATCCTGCTGGTGGAAACGATCTTTGATACAGCTAATGCAAAGgcTGCTCTGTTTGCTATTGATAAACTGTTTGAGGAGTCGTATGAACCAAGACCCATATTTATCTCTGGGACTATTGTGGACAAGAGTGGCCGTACTTTATCAGGGCAGACAGGAGAGGCTTTTGTCATCAGCGTATCCCACGTAAAGCCACTCTGTATTGGTTTGAACTGTGCACTGGGAGCCACTGAAATGAGGCCATTTATCGAAGTGATTGGGAAGAGCACCGGGGCTTTCGTCATATGTTACCCCAACGCAGGTCTCCCCAACACATTTGGAGGCTATGATGAAACACCAGATTGCACTGCTACACATTTAAAGGAGTTTGCAACGGATGGTTTGGTGAATATCGTTGGTGGCTGCTGTGGTACGACGCCAGACCACATACGGGCCATTGCTGAGAGTGTGAAACAATGCCAGCCCAGAGTTCCTCCGACAGACGTGTTCAGCAATTACATGCTGCTTTCTGGTCTGGAGCCATGGATCGGGCCGTACACCAACTTTGTCAACATTGGCGAGCGCTGCAACGTGGCTGGATCACGCAAGTTTGCCAAACTCATCATGACTGGGAATTATGAGGAGGCATTGAGTATAGCTAAAGCACAAGTGGAAATGGGCGCTCAGGTGCTGGATATCAACATGGATGAGGGGATGCTGGAGGGACCCGTTGCCATGGCGCGTTTCTGCAACCTCATCGCCTCCGAGCCTGACATCGCCAGAGTGCCGCTGTGTATCGACTCGTCTAATTTTGCAGTGATCGAGGCAGGTCTGAAGTGCTGCCAGGGCAAGTGCATCGTCAACAGTATCAGCCTGAAGGAGGGAGAAGAGGCCTTCCTCAAACACGCCAAACAAGTGCATCGCTACGGTGCCGCCGTCGTCGTTATGGCTTTTGATGAAGAAGGGCAGgctacTGAAATTGATCAGAAGGTCAAGATCTGCACAAGAGCCTATCACCTCCTAACCAAAAAGGTGGGCTTTAACCCCAATGACATCATCTTCGACCCCAACATCCTGACCATTGGCACCGGGTTGGAGGAACACAACATGTACGCTATCAACTTCATCAAGGCCACGCGGATTATAAAGGAAACGTTGCCTGGAGCCCGGATCAGTGGTGGTCTGTCTAATTTGTCCTTCTCTTTTCGAGGCATGGATGCCATCAGGGAGGCCATGCACGGAACATTCCTCTACCATGCTATAAAGGACGGGATGGACATGGGGATTGTGAATGCAGGTTCTCTGCCTGTGTATGATGATATTGATAAAGAGCTGCTCGTGCTGTGTGAGAATCTCATCTGGAACCAAGACCCAGATGCCACAGAAAAGCTCCTTCTGTATGCTCAGAACAATGCTAAAGGAGGGAAGAAGGTGATTCAGACAGATGAGTGGAGAAAAGGAAGTGTGGAGGAGAGATTGGAGTATGCCCTTGTTAAGggtatAGAGAAGTTTGTAGTGGAGGACACAGAGGAGGCTCGTGCTCAGACAGATCGTTATTCCCGACCACTCCACATCATTGAGGGGCCGCTCATGAATGGCATGAAGACTGTGGGAGATCTGTTTGGAGCTGGCAAGATGTTCCTGCCACAGGTGATTAAATCAGCCCGTGTGATGAAGAAGGCCGTAGCCTATCTAATTCCCTTtatggagaaagagagggaggagatGATGGCTCTATCCGGAGTGCAGGATGACTCAGATCCTTATCAGGGCACGATAGTTCTGGCCACAGTAAAAGGAGACGTCCATGACATCGGCAAGAACATTGTGGGTGTTGTGCTGGGATGCAACAACTTTCGGGTGATTGATTTAGGAGTGATGATTCCATGTGATCAGATCCTGAAGGTGGCCATTGACAAGAAAGCAGatATTATTGGTTTGTCGggcctcatcacaccatccctCGACGAGATGATTTACGTAGCAAAGGAGATGGAACGTCTGGGCATGAAAATCCCTCTGCTGATTGGAGGAGCCACAACTTCAAAGACTCACACAGCAGTAAAGATTGCCCCTCGATACACCGCTCCTGTTATTCACGTTCTCGATGCATCCCGTAGTGTTGTCGTGTGTTCTCAGCTGTTGGATGAAGGAGTGAGTGAGGATTTCTTTGAGGAGATAACGGACGAGTATGAAGAGATCAGGCAGGATCACTACGACTCTCTTAAGGATAGGCGATACATGTCTCTTGCGCAGGCACGGGAAAAAGGCCTACACATCGACTGGCTCTCACAGCCACCACCAAGTCAGCCACAGTTCCTGGGCACGCGTGTGTTTGACCCATATGACCTGAGGAAGCTGTTGGACTTCATCGACTGGAAGCCTTTCTTTGACGTGTGGCAGCTAAGGGGGAAATATCCCAACCGAGGGTACCCCAAAATCTTTAAAGATAAAACCGTGGGAGAAGAGGCCAGGCGTGTGTTTGACGATGCTCTGCGGCTTCTGAACAGGCTGATTGACAGTAAGGGCCTGCAGGCAAGAGGCATCGTGGGCTTCTGGCGGGCACAAAGCCACGGCGATGACATTCTCGTATACACCGATGATGTCACTCCAACCTTATCTAACCACACTGCTACTTTGTACGGGCTTAGACAGCAGGCAGAGAAGGACTCCGCGAGTTCGGAGCCATACCTCTGTTTGGCGGATTTTGTTGCTCCATTGGAAAGCGGAGTGCAGGACTACGTCGGGCTCTTTGCAGTCGCGGTGTTTGGTGCCGAAAAGCTCAGCCAAGATTTTCAGCGGCAGGGCGATGATTACAGCAGCATAATGGTGAAAGCGCTTGCTGACAGACTCGCTGAGGCGTTTGCTGAGGAGCTCCATGCCCGTGTAAGGAGGGAGTTTTGGGGTTATAGTAAGGAGGGAGATCTGCTGGCTAGCGACCTGCACAAGCTGCGTTACTCTGGCATTCGGCCTGCTCCAGGCTATCCCAGCCAGCCTGACCATACCGAGAAACACACCATGTGGAGACTCGCCCAAATTCAGGAGAAAACTGCTATTGGTCTGACTGAATCACTGGCCATGACTCCAGCTGCAGCTGTATCTGGTCTCTACTTTTCCAACCCCAAATCTACCTACTTTGCTGTGGGCAAGATCACCAAGGAGCAGGTGGAAGATTATGCCAAGAGGAAGGAGATTTCCGTGACTGAGGCAGAGAAATGGCTGGCACCAAACCTGGCCTATGACACCGACTAAGCCACATAACAGCCTGCCCAACAGAACATCTGATCAAAATGGTTTTAAACCTGTGGTTTCGAATGTGGACCCTGAAACTAGATAAGCCAAATTGTTATAGTAGTGGcaaactattattttatttatttttatcaatgACAGTTTGCCTGTCagggtttttcttttaaatgctgtaaatttagTTTTCGCATTTTAAATCCAAGTTCTGGTAAAATTGCACCTTACATACGTATTTAATacgtatttttaaaaagttatataATTGAGCTTATCTGGACGCAAATGCGTGAGATTATTATGGAAAACGTTTTCCACAGTTGTCCCATTTGAAGGGATTTTcccaaataaattatttgtcaAAGCAAGACAAATTATCTCCAAAGATGCTCAAAGTGATTGTCGTAGTTCTTCACTTAATGGTTTTATGTTGTATAGTTGACcatgcctttaaaaaaaaaaaagcatctcaaa

Function


symbol description
mtr Predicted to enable cobalamin binding activity; methionine synthase activity; and zinc ion binding activity. Predicted to act upstream of or within methionine biosynthetic process; methylation; and pteridine-containing compound metabolic process. Predicted to be located in cytoplasm and membrane. Predicted to be integral component of membrane. Is expressed in several structures, including anterior neural tube; central nervous system; digestive system; immature eye; and mesoderm. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; autistic disorder; hematologic cancer (multiple); hyperhomocysteinemia; and methylmalonic aciduria and homocystinuria type cblG. Orthologous to human MTR (5-methyltetrahydrofolate-homocysteine methyltransferase).

NR:

description
PREDICTED: methionine synthase

GO:

id name namespace
GO:0009086 methionine biosynthetic process biological_process
GO:0042558 pteridine-containing compound metabolic process biological_process
GO:0032259 methylation biological_process
GO:0005622 intracellular anatomical structure cellular_component
GO:0008705 methionine synthase activity molecular_function
GO:0008270 zinc ion binding molecular_function
GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity molecular_function
GO:0031419 cobalamin binding molecular_function

KEGG:

id description
K00548 metH, MTR; 5-methyltetrahydrofolate--homocysteine methyltransferase

RNA


RNA id representative length rna type GC content exon number start site end site
XM_026915459.2 True 4492 mRNA 0.49 34 20290593 20316556

Neighbor


gene id symbol gene type direction distance location
zgc:165653 LOC108274081,LOC108437900,LOC105888795 coding upstream 2454 20258874 ~ 20288139 (+)
LOC113527333 LOC108273935 coding upstream 61596 20202594 ~ 20228997 (+)
LOC113527727 LOC108274321 coding upstream 90321 20186805 ~ 20200272 (+)
gpx9 LOC108273566,LOC108439462 coding upstream 273089 20012707 ~ 20017504 (+)
mrpl38 mrpl38 coding upstream 419190 19863312 ~ 19871403 (+)
ryr2a ryr2 coding downstream 2733 20319289 ~ 20500533 (+)
LOC113527089 chrm3 coding downstream 240035 20556591 ~ 20657465 (+)
fmn2b fmn2,fmn2b,LOC108413081,LOC107674408 coding downstream 347138 20663694 ~ 20753768 (+)
hhex hhex,LOC107597790,LOC104952083 coding downstream 596162 20912718 ~ 20918024 (+)
lzts2b LOC108274048,LOC108439452 coding downstream 662631 20979187 ~ 21008385 (+)
LOC113527335 NA non-coding upstream 39119 20234815 ~ 20251474 (+)
G199217 psd non-coding upstream 337285 19950787 ~ 19953308 (+)
G199216 NA non-coding upstream 346127 19944244 ~ 19944466 (+)
G199187 NA non-coding upstream 404605 19876741 ~ 19885988 (+)
G199161 trim65 non-coding upstream 434113 19792634 ~ 19856480 (+)
G199796 NA non-coding downstream 278685 20595241 ~ 20595444 (+)
G200325 NA non-coding downstream 1067520 21384076 ~ 21386033 (+)
G200418 NA non-coding downstream 1293698 21610254 ~ 21610457 (+)
G200420 NA non-coding downstream 1323138 21639694 ~ 21643654 (+)
G200430 NA non-coding downstream 1336675 21653231 ~ 21654736 (+)
LOC113527713 fam196a other upstream 723909 19526642 ~ 19566684 (+)
si:ch211-221j21.3 LOC108273429 other upstream 1478331 18806077 ~ 18812262 (+)
G198737 ppp2r2d,LOC107706599,LOC107653113,LOC107582184,LOC107553689 other upstream 1780434 18441886 ~ 18510159 (+)
pde6gb pde6g,LOC102781464,LOC103367935,LOC102221623 other upstream 2130507 18155145 ~ 18160086 (+)
mta3 LOC108273982,LOC108430512,LOC107582777,LOC107728718,LOC107698822 other upstream 2718528 17545793 ~ 17572065 (+)
si:ch211-216b21.2 LOC108273439,LOC107082319,LOC108429207,LOC107704231,LOC105932487,LOC108246656,LOC108274355,LOC102229454,LOC106946734 other downstream 1140835 21457391 ~ 21500929 (+)
G200571 NA other downstream 1686268 22002824 ~ 22003274 (+)
srsf2a srsf2,LOC106612293,LOC107702465,LOC107566380 other downstream 1691955 22008511 ~ 22012304 (+)
LOC113527202 NA other downstream 1697250 22013806 ~ 22026481 (+)
mrpl27 mrpl27,LOC107665862,LOC108430158 other downstream 2481586 22798142 ~ 22871284 (+)

Expression



Co-expression Network