egr2b (egr2,egr2b,LOC107739063,LOC107596614,LOC107653961,LOC107596611,LOC107593522,LOC107745678)


Basic Information

Item Value
gene id egr2b
gene name egr2,egr2b,LOC107739063,LOC107596614,LOC107653961,LOC107596611,LOC107593522,LOC107745678
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047606.1
NCBI id CM018552.1
chromosome length 26563515
location 7979556 ~ 7990069 (-)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026915476.2
ATGGGGTTGAAGAGAAACCGGAATTCCTGATTCAGAGTGATACATGCACCCGAACCTGTCgatttcttttcatttagtAAACTACATATGTGTCACTTTTATTCTGGGACTGAGTGGTGCTTTTTTGCGCACCAGAAAATGTTCACGTTAAAACTATTTTGTTTGCATGcaaacttttcttcttttcaaccCGGAATAAGTGCGGGCTGTAGCAATTTTCCTACCGCTGGCCCATCGGTGTAAGCAAAAGAGCGAAGTCTCCATTGACAACTATCGCTTGGTTCGTCACAAGGCcgcacagccaatcagatctcGCGACTCCACTGTTCCTTATATGGTCAGTGACGTAACGGTACATCAATGGCTctccataaatacacacatagtACCAATAAGAGGCGCCGTGAGGGTCTGTCAttcaacaaaacacacacagcctgatgAGAGGCTCGCTTTCCTGGTCACATTTGAGTGAGCGCTAAACACTCCCTAGGTTAAGTGACAGCCCTGCTGATGTGAGTTTAGTGTCAGAGGTGAAAAAGCAGAGGGTCATCCGcacgcaaacacaaacacttctcTCGCGACTGAACGATGACCGCTAAAACTTTGGAGAAAAGCCCTGTCACTCTCGGCGGCTTCGTGCACCCGCTGTCCGAGAGCATCTACTCACTGGACGACACCACACCGCTGCCAGCCTCGGTCGCAATTTTTCCAAACAGTGATCTAGGTGGACATTACGACCCAATAAATGGACTTTCAGCAGATGGCTTGGTTAGCGGGGATATGAGCGCAGAGAAGCGCGCCGTCGACCTGCCCTACTCCAGCAGCTTCGCGCAGCCGGCTGGTCCTCGCAGTCAGACGTTTACCTACATGGGCAAGTTCTCCATCGACTCCCAGTATCCGGGCAACTGGAACCCAGAGGGCGTGATCAACATCGTGAGCGCGGGCATCCTGGGCATGACCCAGGCCTCATCGGCGTCCTCTTCgccgtcctcctcctcctcggtGTCTCCCGCTCACTTCTCCAGCACGCTCAGCTGCACGGTGGCTCAGGGCCAGACGGACATGGAGCAGCAGCACATCTACTCCCCTCCTCCGCCCTATTCGGGCTGCGCGGAGGTCTACCAGGACCCGTCCGCATTCCTCTCCACCTCCACGTGCCCCATCTCCTCGTACCCGCCGCCGGCCTACTCCTCTCCTAAACCGAGCGCTGATGCCGGCCTCTTCCCCATCCTCCCGGACTACACCGGCTTTTTCCAGCCCCCGTGCCAGCGGGACGTGCAGTCCATCCCCGAGCGCAAACCTTTTGCGTGCCCTCTCGAGCCTTTCCGGGTGCCGCCGCCTCTTACGCCACTGAACACAATTAGGAACTTCACTTTGGCTGCACCGGTGGCCGAGGGAGCACGCTTACCCGCCGCTTACAGCCCGCAGAACCTGCCACTGAGGCCCATCCTGCGCCCGCGGAAATACCCGAACAGGCCCAGCAAAACGCCCGTGCACGAGCGCCCGTATCCATGCCCGGCTGAGGGCTGCGACCGGCGCTTCTCGCGCTCTGACGAGCTCACCCGGCACATCCGCATCCACACGGGCCACAAGCCCTTCCAGTGTCGCATCTGCATGCGGAACTTCAGCCGCAGCGACCACCTGACCACACACATCCGCACGCACACCGGCGAGAAGCCTTTCGCCTGCGACTACTGCGGCCGCAAATTCGCGCGCAGCGACGAAAGAAAGAGGCACACCAAGATCCACCTGAGGCAGAAGGACAGGAAAGCCACGgtgtcctcatcctcctcttcctcctcggTTCCCGCCGGTGGCTCAAACTCCACGTCCGGAATCAGCCAATGAGGAACCGCGGCGCGCAACCACGACTAGGAAACGGTCGCGATGGTAACCGAGCACGCGCAGCCAAATCCTCAGCACCGAACTGAGTTAAGTCATCATACAGTGTTTACTTTGCAGGTGCACATGGACAGGTGTAAACAAATCAGGTGTTCAATTCAAAGCAAAAAACGGGAAATGACCTGAAATCACTTTGGATGAGGGACACTAACAGTGCGCGTCCTCGAATGGCACGCTGTTTTTCTGACTTTCTCAGTCACATGTTGACTGATCAAACGCACTTTGTTTGTATATTTAggttaaataatttaatggaATAACCTTAAACAGCATGTGGGAGTGTACGTATTCTACTGACAGTGTGAGATGTCCGTGTTGGCCACATGAGAGAGTGGGCTTTAATGCTAAAGCCGCTTTCTGCAATAAGTCGGAACAGTTAATCTAATGTGTGAGATGAATCtaactctctctttcctcctgtTTATTGTGCCTTCGTCCGTTCTTTTATTGTACATAACTGCATATGTGCGGAGGCATTTAAACAGTGTACAGTGGATCCtttaataagtttttttttttttttgaaaaaaaaaaaaaatctctattttTGTACAACTTGTTTGGTGTTGCATTGTTCCATGGTGgctaaaaaaagtaaatgtaaataatagaTCTCATTGTTTTGTGAATGTCATATATAATTGGAATGAAATAACTAACGCAGGTTAGTAACTTTCtgtcatcattaaaaaaaaacataatcaatAAAACCCAAAGTCTGAAATG
>XM_034309107.1
TTGGAGAGCGATCCGATCGGATGAGGAGCCCAAGCTATCCcaagagcgtgtgtgtgtgtatgtgtgtgtgtatgtgtgtgtgtgtatgccggatagtgtttgtgtgagtgtgttgctACTGGATCAGTGTAATGCTCTTGGAGGAGCCCACTCATGTGATGGGATTCACAAAGAGCCACTTCTCTCCAAGCCCTGATAATATGGCTTGGTTAGCGGGGATATGAGCGCAGAGAAGCGCGCCGTCGACCTGCCCTACTCCAGCAGCTTCGCGCAGCCGGCTGGTCCTCGCAGTCAGACGTTTACCTACATGGGCAAGTTCTCCATCGACTCCCAGTATCCGGGCAACTGGAACCCAGAGGGCGTGATCAACATCGTGAGCGCGGGCATCCTGGGCATGACCCAGGCCTCATCGGCGTCCTCTTCgccgtcctcctcctcctcggtGTCTCCCGCTCACTTCTCCAGCACGCTCAGCTGCACGGTGGCTCAGGGCCAGACGGACATGGAGCAGCAGCACATCTACTCCCCTCCTCCGCCCTATTCGGGCTGCGCGGAGGTCTACCAGGACCCGTCCGCATTCCTCTCCACCTCCACGTGCCCCATCTCCTCGTACCCGCCGCCGGCCTACTCCTCTCCTAAACCGAGCGCTGATGCCGGCCTCTTCCCCATCCTCCCGGACTACACCGGCTTTTTCCAGCCCCCGTGCCAGCGGGACGTGCAGTCCATCCCCGAGCGCAAACCTTTTGCGTGCCCTCTCGAGCCTTTCCGGGTGCCGCCGCCTCTTACGCCACTGAACACAATTAGGAACTTCACTTTGGCTGCACCGGTGGCCGAGGGAGCACGCTTACCCGCCGCTTACAGCCCGCAGAACCTGCCACTGAGGCCCATCCTGCGCCCGCGGAAATACCCGAACAGGCCCAGCAAAACGCCCGTGCACGAGCGCCCGTATCCATGCCCGGCTGAGGGCTGCGACCGGCGCTTCTCGCGCTCTGACGAGCTCACCCGGCACATCCGCATCCACACGGGCCACAAGCCCTTCCAGTGTCGCATCTGCATGCGGAACTTCAGCCGCAGCGACCACCTGACCACACACATCCGCACGCACACCGGCGAGAAGCCTTTCGCCTGCGACTACTGCGGCCGCAAATTCGCGCGCAGCGACGAAAGAAAGAGGCACACCAAGATCCACCTGAGGCAGAAGGACAGGAAAGCCACGgtgtcctcatcctcctcttcctcctcggTTCCCGCCGGTGGCTCAAACTCCACGTCCGGAATCAGCCAATGAGGAACCGCGGCGCGCAACCACGACTAGGAAACGGTCGCGATGGTAACCGAGCACGCGCAGCCAAATCCTCAGCACCGAACTGAGTTAAGTCATCATACAGTGTTTACTTTGCAGGTGCACATGGACAGGTGTAAACAAATCAGGTGTTCAATTCAAAGCAAAAAACGGGAAATGACCTGAAATCACTTTGGATGAGGGACACTAACAGTGCGCGTCCTCGAATGGCACGCTGTTTTTCTGACTTTCTCAGTCACATGTTGACTGATCAAACGCACTTTGTTTGTATATTTAggttaaataatttaatggaATAACCTTAAACAGCATGTGGGAGTGTACGTATTCTACTGACAGTGTGAGATGTCCGTGTTGGCCACATGAGAGAGTGGGCTTTAATGCTAAAGCCGCTTTCTGCAATAAGTCGGAACAGTTAATCTAATGTGTGAGATGAATCtaactctctctttcctcctgtTTATTGTGCCTTCGTCCGTTCTTTTATTGTACATAACTGCATATGTGCGGAGGCATTTAAACAGTGTACAGTGGATCCtttaataagtttttttttttttttgaaaaaaaaaaaaaatctctattttTGTACAACTTGTTTGGTGTTGCATTGTTCCATGGTGgctaaaaaaagtaaatgtaaataatagaTCTCATTGTTTTGTGAATGTCATATATAATTGGAATGAAATAACTAACGCAGGTTAGTAACTTTCtgtcatcattaaaaaaaaacataatcaatAAAACCCAAAGTCTGAAATGTTTGTTGCAAGCtaaaattcattttcatattcacattacatattatatagcAGTAGGAAAGTCTGATGTACACCTGAATAGGAAATTCCCAATTTCACACCAGTCAGATCTGACTCACTGTCTCACAaggacacacacccacatacccacccacccacacacacatatacaaacattacacacattacattatcCTTGTAATGCAGCAAACTAATGCCATGCCTACACTTAACCTTAAGCTTAACCTCAGAAACCAAAAGGATGCCTTTTTGCtcttttagtttatttacacagtgtcccaaaagtctccatatataGGGATCTATGCTTGCCAGCACCACATaggttgtgccttcatcagtggatgttcggatatccacttctcagttggtccgcaacacttccagtctttctgaatttgttaataTGTTTGGCAAGAGTGTCGTGTGTTATGTGCTTAccatttttcctgttaaagtccatcgcaaccttgtgacagcttcccga

Function

symbol description
egr2b Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within embryonic organ development and nervous system development. Predicted to be located in nucleus. Is expressed in several structures, including nervous system; neural crest; neural keel; neural plate; and neural rod. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 1D; Charcot-Marie-Tooth disease type 3; Charcot-Marie-Tooth disease type 4E; and motor peripheral neuropathy. Orthologous to human EGR2 (early growth response 2).
egr2 Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and ubiquitin protein ligase binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in nucleoplasm. Implicated in Charcot-Marie-Tooth disease type 1D; Charcot-Marie-Tooth disease type 3; Charcot-Marie-Tooth disease type 4E; and motor peripheral neuropathy.

NR:

description
PREDICTED: E3 SUMO-protein ligase EGR2

GO:

id name namespace
GO:0048168 regulation of neuronal synaptic plasticity biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0071320 cellular response to cAMP biological_process
GO:0021575 hindbrain morphogenesis biological_process
GO:0071371 cellular response to gonadotropin stimulus biological_process
GO:0043066 negative regulation of apoptotic process biological_process
GO:0021654 rhombomere boundary formation biological_process
GO:0035914 skeletal muscle cell differentiation biological_process
GO:0048932 myelination of posterior lateral line nerve axons biological_process
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0046872 metal ion binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function

KEGG:

id description
K12496 EGR2; early growth response protein 2

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026915476.2 True 2631 mRNA 0.52 2 7980063 7982977
XM_034309107.1 False 2575 mRNA 0.50 2 7979556 7990069

Neighbor

gene id symbol gene type direction distance location
tmem26b tmem26 coding downstream 169790 7804520 ~ 7809766 (-)
slc16a9b slc16a9 coding downstream 399684 7574076 ~ 7579872 (-)
fam13c fam13c coding downstream 418806 7547063 ~ 7560750 (-)
zgc:171971 LOC108273425 coding downstream 536844 7435509 ~ 7442712 (-)
ube2d1b ube2d1,ube2d1b,LOC106607701,LOC105891213,LOC107717106,LOC107553913,LOC107733527,LOC105010549 coding downstream 551722 7421966 ~ 7427834 (-)
jmjd1cb jmjd1c,jmjd1cb,LOC108412835 coding upstream 31465 8021534 ~ 8141060 (-)
LOC113527613 cyp26a1,LOC108273895,LOC108412396,LOC103044660,LOC107745679,LOC107653962 coding upstream 208015 8198084 ~ 8201220 (-)
exoc6 exoc6,LOC107654070 coding upstream 217875 8207944 ~ 8261110 (-)
adam8b LOC108273892 coding upstream 279522 8269591 ~ 8282862 (-)
LOC113527290 ffar4 coding upstream 311265 8301334 ~ 8302419 (-)
G192665 ado non-coding downstream 2402 7974214 ~ 7977154 (-)
G192611 NA non-coding downstream 101857 7874766 ~ 7877699 (-)
G192585 NA non-coding downstream 136922 7842060 ~ 7842634 (-)
G192584 NA non-coding downstream 137609 7841629 ~ 7841947 (-)
G192583 NA non-coding downstream 138096 7840363 ~ 7841460 (-)
G192685 NA non-coding upstream 81853 8071922 ~ 8126557 (-)
G192681 NA non-coding upstream 100616 8090685 ~ 8095357 (-)
G192881 sun1 non-coding upstream 389158 8379227 ~ 8383599 (-)
G192937 NA non-coding upstream 439235 8429304 ~ 8436084 (-)
G192948 NA non-coding upstream 462128 8452197 ~ 8455303 (-)
ank3b ank3,LOC107746453,LOC107654059 other downstream 212044 7601218 ~ 7767512 (-)
ccdc6b ccdc6,ccdc6b,LOC107695538,LOC107654058,LOC107727062,LOC107746455 other downstream 383675 7581350 ~ 7595881 (-)
ipmkb ipmk other downstream 561178 7400000 ~ 7418378 (-)
itga3b itga3 other downstream 1385166 6546941 ~ 6594390 (-)
LOC113527291 LOC108274042 other downstream 2188286 5768528 ~ 5791270 (-)
si:dkey-94l16.4 LOC108273749 other upstream 857593 8847662 ~ 8857748 (-)
LOC113527700 shisa6,LOC108273473,LOC108424875,LOC107706559 other upstream 1378148 9368217 ~ 9419487 (-)
trnam-cau_28 NA other upstream 1525745 9515814 ~ 9515885 (-)
trnar-ucg_9 NA other upstream 1526003 9516072 ~ 9516144 (-)
LOC113527759 LOC108273488 other upstream 1597097 9587166 ~ 9590116 (-)

Expression


Co-expression Network