LOC117595680 (rac1,RAC1,LOC108273830,LOC108437155,LOC105898786,LOC108412270)


Basic Information

Item Value
gene id LOC117595680
gene name rac1,RAC1,LOC108273830,LOC108437155,LOC105898786,LOC108412270
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047606.1
NCBI id CM018552.1
chromosome length 26563515
location 8395833 ~ 8401469 (+)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_034309288.1
agagggaAGGAGTTTATGGCTTAGGAGCAAGAAGAGGGCGTTAAAGGAGCTGTGATTGTATCCTGAGTTGTTTTTGGGTGGTGGCTGCTGCTGATTGTTTCACTGGAGCATTTCTCGCTAGCAGAGGAGTCTGGAATGCAGCTTACTGATCAACTAGCAGCAGAGAAACAGCTGTGACATGCAGGCCATAAAGTGTGTAGTGGTCGGAGacggggCAGTCGGAAAAACATGCCTTCTGATCAGCTACACCACAAATGCCTTCCCCGGAGAGTACATCCCCACAGTgttTGATAATTATTCTGCAAATGTAATGGTAGATGGGAAGCCAGTGAACCTGGGGCTGTGGGACACAGCAGGACAGGAGGACTACGACAGACTGAGACCACTCTCCTATCCTCAAACGGTACAGCGCCGAGAGCAAACTCAATGCAGAGAcgtgtttttaatttgtttctcGCTGGTGAGCCCTGCCTCGTTCGAGAACGTCCGTGCCAAATGGTATCCTGAGGTCAGACATCACTGCCCCAACACCCCAATCATTCTTGTTGGGACCAAGATCGACTTAAGAGACGACAAGGACACTATTGAGaagctgaaagaaaagaaactcacTCCCATTACTTACCCACAAGGCCTTGCTATGGCTAAAGAAATAGGTTCTGTGAAATATCTGGAATgctcagctttaactcagcgtGGCCTTAAGACAGTGTTCGACGAAGCCATCCGTGCAGTCCTGTGCCCACCGCCGGTCAAAAAGCCAAAGCCAAAGTGCCGTCTCCTCTGAAGAAGTCGTCCATAAAGAACCATCTGCAGTCTGCACTCGCCTGAGGAGAGGTTTCAGGAATAGTGGGGAGGGAGGACGTGTTAGGAGAAAGAGGGAAGACTCTATGAACCATACCCATACATCTCTCTTACTTACATATTGTAGTTCTAATTAGATTTGCTTCTCTGAGTCTGTTTTAGGATCCTAGAGTTTGTCTCGAGGACATGGGGATGCGTTTCCTTGTTATATCCCTTCACACTAAGTAATTCCTGCTGCcttttaataatgtgtttttcgTGTTTATGTAATGGTAAACCAAATGatcctttctttatttcatccATCAGAGcctatatattttgtttacacactgcatttttttttatagaaaatgaaaagttaCCAAAAATGCAAACCTGCTTATAATAGCTTTTACTTTTGTAGGAAAGAGTCCACAATTCAGAAGTTGCTGAGTGCTtacttagatagatagatgtactttattgatccctgagggGAAATTTGGGAATCACTCTTATGatattattagtttttattagttttattagtttACTCATTTAGTGTACATATTGGGGTCAAACATTTGGTACATAAATGTTACACTAGAAAAAGCACgtattcactgactcactgtcATCTGAGCACtctaaattacaaaacaaaatttgGCTCAATGCTTATTAATATGTGCTGCATTTACTATGCAGTCATTGTGAAAGAACTTTTTATTCCCACGCAGTATTGTATAAAGCCTGTAGTTTGGCCGATGAATAGAATGTGGACAGATGTAGAATGAGAATTGTCTGTCCAAAATCTGCTGTCAGTATGGAATCACGCCCCCAAGAGAAGTGGATCTTGGATCACCAAGTTTAACTGAAATTCCTTTTCACAGGAAGGCACACTGAGAGGACATATAAGAGAACAAGTCGAGAACAATTCCCAACAGATGTCTTATTTTTTATCTCTTGTATGATTTCAATCATGtcagattgttttgttttgtttttactgtattCCAACTACTTTTACAATGTATTAACAATATTCTctggaaatgaaaaacagtGTCCTTTGTCCTAAGCTTTAGTGATTTTATTCAAGTGTTAATCAGTTAGTTCCTCTGAAATCAGTTTCCACTGTCATGATTATGTCTGTTGAATAGAGATTTACTTCACGTG
>XM_034309289.1
aaaatcagagggaAGGAGTTTATGGCTTAGGAGCAAGAAGAGGGCGTTAAAGGAGCTGTGATTGTATCCTGAGTTGTTTTTGGGTGGTGGCTGCTGCTGATTGTTTCACTGGAGCATTTCTCGCTAGCAGAGGAGTCTGGAATGCAGCTTGTGAGCTCAGTTTACAGAGGAAGTTTTCACCATTTGGCTTGATTTGCTGTGGTATTTTTGTGAAGGCGGTTTAACTCCAGTGTcgcagagtgtgtgagagagtgtgtgtgtgtgagagagtgtgtgtgtgagagagtgtgtgtttgatttcttCAGACTGATCAACTAGCAGCAGAGAAACAGCTGTGACATGCAGGCCATAAAGTGTGTAGTGGTCGGAGacggggCAGTCGGAAAAACATGCCTTCTGATCAGCTACACCACAAATGCCTTCCCCGGAGAGTACATCCCCACAGTgttTGATAATTATTCTGCAAATGTAATGGTAGATGGGAAGCCAGTGAACCTGGGGCTGTGGGACACAGCAGGACAGGAGGACTACGACAGACTGAGACCACTCTCCTATCCTCAAACGGAcgtgtttttaatttgtttctcGCTGGTGAGCCCTGCCTCGTTCGAGAACGTCCGTGCCAAATGGTATCCTGAGGTCAGACATCACTGCCCCAACACCCCAATCATTCTTGTTGGGACCAAGATCGACTTAAGAGACGACAAGGACACTATTGAGaagctgaaagaaaagaaactcacTCCCATTACTTACCCACAAGGCCTTGCTATGGCTAAAGAAATAGGTTCTGTGAAATATCTGGAATgctcagctttaactcagcgtGGCCTTAAGACAGTGTTCGACGAAGCCATCCGTGCAGTCCTGTGCCCACCGCCGGTCAAAAAGCCAAAGCCAAAGTGCCGTCTCCTCTGAAGAAGTCGTCCATAAAGAACCATCTGCAGTCTGCACTCGCCTGAGGAGAGGTTTCAGGAATAGTGGGGAGGGAGGACGTGTTAGGAGAAAGAGGGAAGACTCTATGAACCATACCCATACATCTCTCTTACTTACATATTGTAGTTCTAATTAGATTTGCTTCTCTGAGTCTGTTTTAGGATCCTAGAGTTTGTCTCGAGGACATGGGGATGCGTTTCCTTGTTATATCCCTTCACACTAAGTAATTCCTGCTGCcttttaataatgtgtttttcgTGTTTATGTAATGGTAAACCAAATGatcctttctttatttcatccATCAGAGcctatatattttgtttacacactgcatttttttttatagaaaatgaaaagttaCCAAAAATGCAAACCTGCTTATAATAGCTTTTACTTTTGTAGGAAAGAGTCCACAATTCAGAAGTTGCTGAGTGCTtacttagatagatagatgtactttattgatccctgagggGAAATTTGGGAATCACTCTTATGatattattagtttttattagttttattagtttACTCATTTAGTGTACATATTGGGGTCAAACATTTGGTACATAAATGTTACACTAGAAAAAGCACgtattcactgactcactgtcATCTGAGCACtctaaattacaaaacaaaatttgGCTCAATGCTTATTAATATGTGCTGCATTTACTATGCAGTCATTGTGAAAGAACTTTTTATTCCCACGCAGTATTGTATAAAGCCTGTAGTTTGGCCGATGAATAGAATGTGGACAGATGTAGAATGAGAATTGTCTGTCCAAAATCTGCTGTCAGTATGGAATCACGCCCCCAAGAGAAGTGGATCTTGGATCACCAAGTTTAACTGAAATTCCTTTTCACAGGAAGGCACACTGAGAGGACATATAAGAGAACAAGTCGAGAACAATTCCCAACAGATGTCTTATTTTTTATCTCTTGTATGATTTCAATCATGtcagattgttttgttttgtttttactgtattCCAACTACTTTTACAATGTATTAACAATATTCTctggaaatgaaaaacagtGTCCTTTGTCCTAAGCTTTAGTGATTTTATTCAAGTGTTAATCAGTTAGTTCCTCTGAAATCAGTTTCCACTGTCATGATTATGTCTGTTGAATAGAGATTTACTTCACGTG

Function

symbol description
rac1 Enables GTP binding activity; GTPase activity; and enzyme binding activity. Involved in several processes, including plasma membrane bounded cell projection assembly; positive regulation of cellular component biogenesis; and regulation of cell migration. Acts upstream of or within actin cytoskeleton organization; positive regulation of lamellipodium assembly; and ruffle organization. Located in several cellular components, including recycling endosome membrane; ruffle membrane; and trans-Golgi network. Is extrinsic component of cytoplasmic side of plasma membrane. Is active in glutamatergic synapse and postsynapse. Colocalizes with actin filament. Implicated in autosomal dominant mental retardation 48; colon adenocarcinoma; and pancreatic adenocarcinoma. Biomarker of colon adenocarcinoma; colon adenoma; colorectal cancer; and pancreatic ductal adenocarcinoma.

GO:

id name namespace
GO:0060071 Wnt signaling pathway, planar cell polarity pathway biological_process
GO:0072659 protein localization to plasma membrane biological_process
GO:0042074 cell migration involved in gastrulation biological_process
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity biological_process
GO:0045087 innate immune response biological_process
GO:0071542 dopaminergic neuron differentiation biological_process
GO:0021799 cerebral cortex radially oriented cell migration biological_process
GO:0045453 bone resorption biological_process
GO:0045740 positive regulation of DNA replication biological_process
GO:0034446 substrate adhesion-dependent cell spreading biological_process
GO:0003382 epithelial cell morphogenesis biological_process
GO:0002551 mast cell chemotaxis biological_process
GO:0021831 embryonic olfactory bulb interneuron precursor migration biological_process
GO:0007520 myoblast fusion biological_process
GO:0006954 inflammatory response biological_process
GO:0030168 platelet activation biological_process
GO:0031295 T cell costimulation biological_process
GO:0038095 Fc-epsilon receptor signaling pathway biological_process
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis biological_process
GO:0035025 positive regulation of Rho protein signal transduction biological_process
GO:0048532 anatomical structure arrangement biological_process
GO:0006972 hyperosmotic response biological_process
GO:0048813 dendrite morphogenesis biological_process
GO:0043065 positive regulation of apoptotic process biological_process
GO:0048261 negative regulation of receptor-mediated endocytosis biological_process
GO:0043652 engulfment of apoptotic cell biological_process
GO:0002093 auditory receptor cell morphogenesis biological_process
GO:0050690 regulation of defense response to virus by virus biological_process
GO:0090103 cochlea morphogenesis biological_process
GO:0045216 cell-cell junction organization biological_process
GO:0032707 negative regulation of interleukin-23 production biological_process
GO:0097178 ruffle assembly biological_process
GO:0006184 obsolete GTP catabolic process biological_process
GO:0097190 apoptotic signaling pathway biological_process
GO:0008283 cell population proliferation biological_process
GO:0048011 neurotrophin TRK receptor signaling pathway biological_process
GO:0030838 positive regulation of actin filament polymerization biological_process
GO:0016601 Rac protein signal transduction biological_process
GO:0060263 regulation of respiratory burst biological_process
GO:0007411 axon guidance biological_process
GO:0001934 positive regulation of protein phosphorylation biological_process
GO:0030334 regulation of cell migration biological_process
GO:0016032 viral process biological_process
GO:0010310 regulation of hydrogen peroxide metabolic process biological_process
GO:0007160 cell-matrix adhesion biological_process
GO:0010592 positive regulation of lamellipodium assembly biological_process
GO:0071526 semaphorin-plexin signaling pathway biological_process
GO:0051668 localization within membrane biological_process
GO:0032587 ruffle membrane cellular_component
GO:0005802 trans-Golgi network cellular_component
GO:0005829 cytosol cellular_component
GO:0042470 melanosome cellular_component
GO:0000139 Golgi membrane cellular_component
GO:0019897 extrinsic component of plasma membrane cellular_component
GO:0001891 phagocytic cup cellular_component
GO:0030027 lamellipodium cellular_component
GO:0003924 GTPase activity molecular_function
GO:0005525 GTP binding molecular_function
GO:0030742 GTP-dependent protein binding molecular_function
GO:0019901 protein kinase binding molecular_function
GO:0051022 Rho GDP-dissociation inhibitor binding molecular_function
GO:0031996 thioesterase binding molecular_function

KEGG:

id description
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1

RNA

RNA id representative length rna type GC content exon number start site end site
XM_034309288.1 False 1965 mRNA 0.41 7 8395839 8401469
XM_034309289.1 True 2097 mRNA 0.41 6 8395833 8401469

Neighbor

gene id symbol gene type direction distance location
zgc:152977 sun1 coding upstream 2239 8359423 ~ 8393594 (+)
myof myof coding upstream 37661 8326152 ~ 8358172 (+)
tubgcp2 tubgcp2,gcp2,LOC106589265 coding upstream 71308 8312121 ~ 8324525 (+)
reep3b reep3,LOC108412837 coding upstream 218634 8149279 ~ 8177199 (+)
nrbf2b nrbf2 coding upstream 376619 8011864 ~ 8019214 (+)
LOC113527453 LOC101159016,LOC101485652,LOC100697553,LOC103373537,LOC107376513,LOC108239271 coding downstream 6660 8408129 ~ 8413358 (+)
LOC113527454 rac1,RAC1,LOC105898786,LOC106601744,LOC108437155,LOC107569188,LOC105026138 coding downstream 22827 8424296 ~ 8431581 (+)
LOC113527452 rac1,RAC1,LOC106601744,LOC105898786,LOC105026138,LOC108239271,LOC107376513 coding downstream 31715 8433184 ~ 8440360 (+)
LOC113527605 LOC108274277,LOC108412267,LOC107753296,LOC107695555,LOC107569185,LOC107745655,LOC107684747 coding downstream 50738 8452207 ~ 8464652 (+)
mosmob c13h16orf52,cunh16orf52,C20H16orf52,c16orf52.L,c17h16orf52,LOC105910214,LOC107569180,LOC106518731 coding downstream 64162 8465631 ~ 8473820 (+)
G192737 NA non-coding upstream 7716 8310878 ~ 8388117 (+)
G192716 NA non-coding upstream 125607 8269148 ~ 8270226 (+)
LOC117598703 NA non-coding upstream 134410 8259214 ~ 8261423 (+)
G192644 NA non-coding upstream 254773 8126773 ~ 8141060 (+)
G192650 NA non-coding upstream 324241 8069143 ~ 8071592 (+)
G192760 NA non-coding downstream 112913 8514382 ~ 8515934 (+)
LOC117598667 NA non-coding downstream 195185 8596654 ~ 8601770 (+)
G192858 NA non-coding downstream 516571 8918040 ~ 8918245 (+)
G193170 NA non-coding downstream 655930 9057399 ~ 9093247 (+)
G193169 NA non-coding downstream 756690 9158159 ~ 9158568 (+)
G192484 ank3 other upstream 767722 7605981 ~ 7628111 (+)
tfam tfam other upstream 959461 7428545 ~ 7436372 (+)
asah2 asah2,LOC107598643 other upstream 1559450 6822740 ~ 6836383 (+)
LOC113527389 NA other upstream 1667442 6725321 ~ 6728391 (+)
G191581 NA other upstream 2412596 5969743 ~ 5983237 (+)
LOC113527534 dnah9 other downstream 867024 9268493 ~ 9357961 (+)
G193383 LOC108273473 other downstream 966774 9368243 ~ 9369915 (+)
trnaq-cug_13 NA other downstream 1110700 9512169 ~ 9512401 (+)
trnaq-cug_14 NA other downstream 1111091 9512560 ~ 9512631 (+)
mrpl58 mrpl58 other downstream 1111315 9512784 ~ 9515616 (+)

Expression


Co-expression Network