fzd4 (fzd4)



Basic Information


Item Value
gene id fzd4
gene name fzd4
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information


Item Value
chromosome id NC_047608.1
NCBI id CM018554.1
chromosome length 25848897
location 1682765 ~ 1690584 (-)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence


>XM_026943604.2
GCGCCTGTCCGAGCGCTCCAGTCCGGTGAAGCTCGCGACCCGGGGGTTTCAGCGCCACGTGCATAGAGGAGACGGGATCCCGGGATGTTCTTTTCCATCACAGAGCGCAAGCCACACTCGGGATAATTCTCATCGTCGCTGGTATTAATTCTCTGCTTGTCTTggagtctttcttttttctgtttttcctggGATGGAAGAGTGCGCGCGCGGCACTATGGCTTGGAGCTCGCGCTCGGGTCTGGCGCTGCCCGCtcgcctgctgctgctgctgctgctgctgctgttgagCGGCGGGGCAGGAGTGGCGCGCGCGTTCGGTACAGGCGgcgcggaggaggaggaggagtcgGAGTCCGCGTGCGAACCGATCCGCATGTCCATGTGCCGTGACCTGGGCTACAACGTCACGCGCATGCCGAACCTGGTTGGCAACGTGCTGCAGGCGGACGCCGAGTTACAGCTGTCCACTTTCACCCCGCTCATCCAGTACGGCTGCGCCAAACAGCTgcggTTCTTCCTGTGTTCAGTCTACGCCCCAATGTGTACGGAGAAGGTTCCGGAGCTGATTGGTCCGTGTGGCAGCATGTGTCTGTCCGTTCAGAGGAAGTGTTTGCCCGTGCTGCAGGAGTTCGGCTTCTCGTGGCCTGACCTGCTGAACTGCAGCTTGTTCCCGCCCACAAATGATCACGCCCACATGTGCATGGAGGGTCCGAGTGAGGAGGACGAGGACGACGCTCGCTTTCCATCGGTGCGCACGCTGCGGCCACGCCACGGCCTTGACGCTGAGTGCATCCCTCTTGACCATGACCCTGGAGATGACCCCACTCCCCCAGACCGCTACGTGTGGTCAAAGCGCAGCGGTTCCTGCGTGCTGCAGTGTGGCTACGACTCTGGATTATACAGCCGCTCTGCCAAGACATTTGCTGATGCCTGGATGGCtctgtgggcggggctttgcTTCGTCTCCACCTCCTTCACAGTGTTGACATTCCTGCTGGACTCGGGACGGTTCTCCTACCCGGAGCGTCCCATTGCATTTCTGAGTGTGTGCTACAACGCATACAGCGCCGCCTTTCTGGTGTTGCTAGCAGCTGGACGTGAGCGCGTGTCATGTGATTCGGATGAGGCTGCTGTCCCCGTCCTGGCTCGGGATGGATTAAAGAACTCGGGCTGCGCTGTGGTCTTCTTGTTAGCTTACTTTTTCGGTATGGCAAGCTCCGTATGGTGGGTGATCCTCACACTAACGTGGTTCCTAGCAGCAGGACTTAAGTGGGGACACGAGGCCATTGAGATGCACAGCTCCTACTTCCACGTGGCAGCGTGGGCCATCCCAGCGATCAAAACCATCGTGGTGCTCGTCATGCGCCTGGTCGATGCGGATGACCTCACCGGCCTGTGCTACGTCGGCAACCAGAACCTGGAGGCGCTCACTGGTTTCGTGGTGGCACCACTGTTTACTTATTTGGCTGTTGGGACGCTGTTCATTGCCGCCGGACTTGTCTCGCTGTTTAAGATCCGGTCCAACTTGCAGAAGGACGGCGCCAAGACGGACAAGCTGGAGCGGCTTATGGTAAAGATCGGCGTCTTCTCCGTGCTCTACACCGTCCCGGCCTCCTGCGTTGTGGCGTGCTACTTCTACCGCGTCTCAAATTGGTCTGACTTCCAGCGAGCGCCGAGTGACTCGTACGCCGCTGCTGAGATGCTCAGGATCTTCATGTCCTTGCTGGTGGGCGTAACTTGTGGCATGTGGGTGTGGTCTGCCAAGACACTGCAGACCTGGAAACGTCGCTGTCTACGCCTGCTCTGCCCACAGAGCAACACGCGACGGACCCACACCAGCAAAAACGGCGGTGGTAAAGGGAATGAGACTGTGGTGTGAGGCAGTGAGGAACCGTGTGACATGGACAGAGCGACATCTGGTGGACACTTGCTGTCACTGTAGCACATCATTGTTCTCTCTCGACAAATATCaccagattgttttttttttacactggacAACATGGCGCAGTGGAAAACATGCAGTAAGATACAATAGGAAGTTGTGTCAGGACAGGAAGCTGTGACGTGGCAGGAAGTAGCAGGGCCACTTCTCCAATTTTGTGAATGCACAGTGAGCCGACTGAAGTGCCTTGTTTCTCAGACCTCCTGCTACTCTTCACGTTGTGGTAGCTTTCATCTATAATGCAGCAAAGACacctgggaaatggagtttttCCTCTTCTCAGTAAACAGCACCATTTACCTCGGATCAAGACCACAGCCATGTGTCCTCTGCGTTCGGATTCTTGCTGTATGCAAAATGGCCACTCACCATCTCTTCCGTCATTAGCACTATGTAGCAAAAAACAGATCGAGTGATGTTCAGTAGTGGTTTTGTTTCACTGCAGCTCACTCCAATGTGGATGTATCCTCAGTGCCACACTCTATTCACTACATAGTTCACAGAAAACCCCTCGAACATCATCAGTCCCTTGTGGACATGTGGAGTACATCATTTGtatgcagtgcattatgggattttgTGTGTGCACTGGATGTCCTCCATTACAGGCCCTTTTCTTGTTTCCTGGGTAGCGACATAACCAGAGCAGGGTTTTCCCTCGGCTTTCAGAGGGCTTAGGTGCTGCCTGGGCTCTGGGGCCGCGGTGCTGGTTGGGGGTTTGAAATTATTCGAAGGaaattttaagttatttaaaaaaattttatgttgtttgcgaccatttgtatttgtatttgtgaaGAAAACCTGGCAACACTTATCGTACTTATAGTCAAAAGTCTATTCATTTCACCAAGTACCATGTTGGAGATTTAATAAACGTATATATGGAgctgcatttatatttatatatatatatataaatggcaaaatatgctacaaataattttacaaaaatgaaatatgcaaattttgTAGGCAGTCAAGGCACCTTGCACAATATGACTGATGAGATGAGGTAGACGAGGACTTGCATCACTGATTTCGACTGGTTCTTACACTACACTAAAGGAACGGGGGAGAAAACTATTTCTGTCAGGGGCAGTTGTGGGAAATGCCACTCAACCCGCAAGCATTTAAGGCTGTTTGTGTTAAGgataacatctttttttttttttttttttttttttttttttttttgaagcggTCAGCACCTGTTTTACATAATAATCCAATGGAGTAGACCGCGTTTTCAAAAAATGCCCTGAGCTTCATTTGGGACGCTCTGAACTgcattttgaaacttttttttttttatatgaaaaaacaCTTTGGCCAGCGGttttcatcagaaaaaaaaaaaaacgctacgCGGTGAACAAAGCGTAACTTTGTTTAGCTACCAAGCCACGTTAGATATTAACGTTAGTCCAGTCGAGGTATCGTTATCTAACGTCATCTAACTAGCTACGCTGCCTAACGTAACTTAATTCAGTATCTACGTGAGTTAGCTAGGTTAGCAATTTCTtaagttatattatattataacattAGTTGTATCTTTTGATATGTTATCAATAGTGCGATATTGATATCGCGTGCACAAAAATccctaaaaaaaagtttataccTGATTTATTCTTTGTTGATGCTTACCATAGTGATGGCTTGCAACTTGCTTATCCGAGTTGATGGTTCCATCCTGAGGTGAAGGTACAGAGAAATGTCCAATCAGCTGTTTGATTAGCAAAGAAATGTCCAATCAGCTGTTTGATTAGCAAAGAAATGTCCAATTAGCTGTTTGATTAGCAAAGAAATGTCCAATCAGCTGTTTGATTAGCAAAGAAATGTCCAATCAGCTGTTTGATTAGCTTTGTGATGAGTTTCTGCCCCAGGCCAATCTAACAAACACTGATTGCTCATTCCTGTTGCCAGCTTACCTTCCCGTCCCAGATCATGCcacttctctgtttcttttttggtCAGCGCATAAAACTCTCACTGTTGTTTTAACTTTCATTCTGATATTTAGTCACCTAAATGCCTCATTTGGTTTAAGGTGCTCTGCAAAAATACTTAGGCCTCTATCTAAGCCTTTCTATGGTGGGGAAAACCCTGCCAGAGGTCCAGATATTAGCAACAGGGTAAAATTAGGACGGatcaaaaaacattaataaatatcttTGAAGTTCACGACTCATAAGTTAGGTGATGAGTTTAACCTGGTGACAGGGAGCTGGGAAAACTTCAGATAACTGCGTCTTATAGAAATTAATACGCATTTTCAAGTGAGTAATAGACCAAGGAAGCCTTATACTcatctttgtaaaaaaaaaaaaaaaaaaaaatcagatgcagtgtgttgatGGTGACCTGatagctgaaaaaaacaaaacaaaactgtgaaATCAGATTACTGGAAATCTGTGTGTTTCCGATTAGAAATCTATTTTTTCTAgttatgcaaatgtaaatgtaaatttaaaaaaaaaaaaaaaaaaaaaaaaa

Function


symbol description
fzd4 Predicted to enable Wnt-protein binding activity. Predicted to be involved in Wnt signaling pathway; negative regulation of canonical Wnt signaling pathway; and retina vasculature morphogenesis in camera-type eye. Predicted to act upstream of or within Wnt signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in extracellular space. Is expressed in central nervous system; neural plate; and neurogenic placode. Human ortholog(s) of this gene implicated in exudative vitreoretinopathy 1. Orthologous to human FZD4 (frizzled class receptor 4).

NR:

description
PREDICTED: frizzled-4

GO:

id name namespace
GO:0007186 G protein-coupled receptor signaling pathway biological_process
GO:0007275 multicellular organism development biological_process
GO:0016055 Wnt signaling pathway biological_process
GO:0016021 integral component of membrane cellular_component
GO:0004930 G protein-coupled receptor activity molecular_function

KEGG:

id description
K02354 FZD4, fz4, CD344; frizzled 4

RNA


RNA id representative length rna type GC content exon number start site end site
XM_026943604.2 True 4453 mRNA 0.47 3 1682765 1690584

Neighbor


gene id symbol gene type direction distance location
LOC113544557 parl coding downstream 85293 1592593 ~ 1597472 (-)
cldn15lb cldn1 coding downstream 94310 1581397 ~ 1588455 (-)
atg16l1 atg16l1,LOC107689588,LOC107551872 coding downstream 101736 1560569 ~ 1581029 (-)
sagb LOC108411842,LOC107756220,LOC107670108,LOC107689591,LOC107600819 coding downstream 124461 1546943 ~ 1558304 (-)
LOC113544537 dgkd coding downstream 142043 1521327 ~ 1540722 (-)
pdgfd pdgfd coding upstream 108096 1798680 ~ 1813081 (-)
gucy1a2 gucy1a2,LOC107706059,LOC107669873 coding upstream 233084 1923668 ~ 1946156 (-)
cwf19l2 cwf19l2 coding upstream 259397 1949981 ~ 1965960 (-)
trnag-ucc_22 NA coding upstream 278828 1969412 ~ 1969483 (-)
naalad2 folh1b,LOC107670141,LOC108412465 coding upstream 328724 2019308 ~ 2035377 (-)
G218720 NA non-coding downstream 678 1624484 ~ 1682087 (-)
G218734 NA non-coding downstream 6551 1675764 ~ 1676214 (-)
LOC117599072 NA non-coding downstream 65827 1603411 ~ 1616938 (-)
G218695 NA non-coding downstream 105554 1576881 ~ 1577211 (-)
LOC113544681 NA non-coding downstream 114574 1546445 ~ 1568191 (-)
G218768 NA non-coding upstream 79631 1770215 ~ 1770452 (-)
G218773 NA non-coding upstream 87162 1777746 ~ 1786974 (-)
G218825 NA non-coding upstream 227129 1917713 ~ 1918020 (-)
G218840 NA non-coding upstream 258694 1949278 ~ 1949551 (-)
G218850 NA non-coding upstream 287458 1978042 ~ 1980907 (-)
trnag-ucc_18 NA other downstream 185354 1497340 ~ 1497411 (-)
trnag-ucc_17 NA other downstream 185659 1496879 ~ 1497106 (-)
G218302 nyap2 other downstream 528065 1154410 ~ 1154700 (-)
G218265 NA other downstream 548747 1080288 ~ 1134018 (-)
mecom LOC108278348,LOC108269179 other downstream 579881 955480 ~ 1102884 (-)
scaf4b LOC108411133 other upstream 590817 2281401 ~ 2320915 (-)
gal3st2 LOC108261785,LOC108277996 other upstream 922273 2612857 ~ 2629901 (-)
G219642 NA other upstream 1197323 2887907 ~ 2963350 (-)
G219651 NA other upstream 1216742 2907326 ~ 2911165 (-)
igsf11 igsf11 other upstream 2036793 3727377 ~ 3807114 (-)

Expression



Co-expression Network