drd2a (drd2,LOC107586233,LOC107670954,LOC107717269,LOC107709110)



Basic Information


Item Value
gene id drd2a
gene name drd2,LOC107586233,LOC107670954,LOC107717269,LOC107709110
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information


Item Value
chromosome id NC_047608.1
NCBI id CM018554.1
chromosome length 25848897
location 8729942 ~ 8772841 (-)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence


>XM_034310393.1
CTCACTCACTCCACCTGCCACACGCGCTCGCTGCGCACGAGGACTTTTCGTGCTGTACTGTACGCGTCACACTTTCACTCCAAACCtccagaggagaaagagaggagaaacaCGGGACATTTGTGGCTCAAAACAAGTTGGAAGGCGACTTTGAAAGAAGTcgggtttatttgtttttcctgtTGGCGTGAAGTCTTGACGAAGTAGTTGGTGAAAGCAGTGAGTTATTTATTCGACTGCTCCTCATGGACAGGCGCATGCGCCGGAGAAAAGTGGATTTAAAACACCTTCGGCTCTGTACTTCTCTGTTAATGAAACTGACACCGTGAAGGGCCTCTTCTTGGCCTCGGACCCTCACAGCTGATGGAAGTCTTGGAGGAGTATGCTTACAATGAAAGCTTCCTCAAAAATGGATTCAATGGCCTCAACACTACAGATGGAGGCAGAAGACATCAGTACAATTATTATGCCATGCTACTCACTCTGCTCATTTTCGTCATCGTCTTCGGAAACGTACTCGTGTGCATGGCTGTGTCAAGAGAGAAAGCTCTACAGACCACTACTAACTACCTGATCGTGAGCTTGGCTGTCGCTGACCTGCTGGTGGCGACTCTGGTTATGCCTTGGGTGGTATATCTTGAGgtggtGGGAGAATGGAGGTTTAGCACAATCCACTGTGACATCTTTGTCACTCTTGATGTTATGATGTGCACAGCAAGCATCCTTAATCTTTGTGCCATTAGCATTGATAGGTATACAGCAGTTGCCATGCCAATGTTGTATAATACACGCTACAGCTCCAAGAGGAGAGTCACAGTCATGATCTCAGTAGTGTGGATCCTGTCCTTTGCCATTTCATGCCCCCTGCTGTTTGGACTCAATAACACAGAGAGCCACAATGAAGCCATGTGTGTAATCGCGAACCCTGCCTTTGTAGTCTACTCGTCTGTTGTGTCCTTCTATGTACCCTTCATCATCACCCTGCTCGTATACGTGCAGATCTACGTAGTGCTGCGTAGACGGCGGAAACGTGTTAGCACAAAGCGCACGTACCCAAGCAGCAACATGGACATGGGTGCTTTGAAGAAATGCACTCACCCTGATGATGTGAAGCTGTGCACGGTCGCTGTGAAGTCCAATGGGAATTTCCCTGTTAATAACAAAAATGTTTTCATAAAGGAGGTGGcaaacaatgaaaatgaaagccAAATGGATGAAATCACAAACCTTAATCCTCCAAACCAGAGGACACTTCAGCAGACAGGTGAGAGTCAGCATGGGCTTCTGCTTGGTTCGAACCACAGTGAAATAGATACAGCACCCTCCGCTCCTGAGCTCAAGCCAACAAGGAACGGAAAGACCTACGACGCCTCCAAAATGGCTAAAGCATTTGAGACTCAGGTGTCTCCCAGTGGCAAAATGCAGACATCAATGAAGTCCATTAGCAAGCGCAAAATCTCTCagcagaaagagaagaaagctACTCAGATGTTGGCTATTGTGCTCGGTGTGTTCATTATATGCTGGCTGCCgttcttcatcacacacataaTGAATACGTACTGTCACGTCCCTGCAGAACTCTACACAGCTTTTACCTGGCTCGGTTACGTCAACAGCGCCGTGAACCCCATCATATACACCACCTTCAATATTGAATTCCGCAAGGCTTTTATTAAGATCCTGCACTGCTGAGAGTGGAATTATCCATAAGTGAAGACAAACACAGCTCATCCACATGTGGCCTACATAAAGCTCCTTCCTGAAGACTGTTTTAAAAGGGAGCTAAACTTGAAGGAGATTACTGGGAATGACACGGATGTACATATGAAGTTGAAGATGTATTATAAAAGCAAGCAATTCTCCCAGTGTCATCTCATGCAACAGTAAGACATTTCTGGATAATTCCTAAGGAGGTGTCATTCAGTATAAGCTTCACAGTATtacttttgtttattaattacacaataaaggTAAAGTAAACATCATTTAGATTATAATACTGCAGTCTTCATAGTGGTGGTAACATACAGCAGTGTAATATgcagcaacagtaagaaaattTTAATACACTAATGCAAGTGTTGATGCTCAGCTGACAAcaaattacatatatacatgtgtgtataaaagtaATATGCACAAGAacaaaaagtgctttttttgaaaataatattgAGGAAATATTGATCCTCATAAACATGGTGGTGCTGTGCATTTTGGTCTCAGCTATCACTATCAAGACGCATTCAATCACTGTAGCTTGATGATTGATGATTTGGTCTTTAGGGTCAAACTGATCCCATGAGAAATTTGTACTAAGTGCAATTTGGTTGGAGTTTGTTAAATTTCATATGAACGAAATCATAAGAAAAGGTACAAATGGTAACCATAACTCAAACTTTGGTGAATGGAGTGTGAGAGGAAAACACCACTCAAGATCATTAAACCAGTTTGCAAAAATTTTGTCACAAAATGACTGTGCAATTATAA
>XM_034310394.1
GTTGGAGAGCCTAAGGCTTGAGGCGCTTGGGAGTAAAAGGGCCTCTTCTTGGCCTCGGACCCTCACAGCTGATGGAAGTCTTGGAGGAGTATGCTTACAATGAAAGCTTCCTCAAAAATGGATTCAATGGCCTCAACACTACAGATGGAGGCAGAAGACATCAGTACAATTATTATGCCATGCTACTCACTCTGCTCATTTTCGTCATCGTCTTCGGAAACGTACTCGTGTGCATGGCTGTGTCAAGAGAGAAAGCTCTACAGACCACTACTAACTACCTGATCGTGAGCTTGGCTGTCGCTGACCTGCTGGTGGCGACTCTGGTTATGCCTTGGGTGGTATATCTTGAGgtggtGGGAGAATGGAGGTTTAGCACAATCCACTGTGACATCTTTGTCACTCTTGATGTTATGATGTGCACAGCAAGCATCCTTAATCTTTGTGCCATTAGCATTGATAGGTATACAGCAGTTGCCATGCCAATGTTGTATAATACACGCTACAGCTCCAAGAGGAGAGTCACAGTCATGATCTCAGTAGTGTGGATCCTGTCCTTTGCCATTTCATGCCCCCTGCTGTTTGGACTCAATAACACAGAGAGCCACAATGAAGCCATGTGTGTAATCGCGAACCCTGCCTTTGTAGTCTACTCGTCTGTTGTGTCCTTCTATGTACCCTTCATCATCACCCTGCTCGTATACGTGCAGATCTACGTAGTGCTGCGTAGACGGCGGAAACGTGTTAGCACAAAGCGCACGTACCCAAGCAGCAACATGGACATGGGTGCTTTGAAGAAATGCACTCACCCTGATGATGTGAAGCTGTGCACGGTCGCTGTGAAGTCCAATGGGAATTTCCCTGTTAATAACAAAAATGTTTTCATAAAGGAGGTGGcaaacaatgaaaatgaaagccAAATGGATGAAATCACAAACCTTAATCCTCCAAACCAGAGGACACTTCAGCAGACAGGTGAGAGTCAGCATGGGCTTCTGCTTGGTTCGAACCACAGTGAAATAGATACAGCACCCTCCGCTCCTGAGCTCAAGCCAACAAGGAACGGAAAGACCTACGACGCCTCCAAAATGGCTAAAGCATTTGAGACTCAGGTGTCTCCCAGTGGCAAAATGCAGACATCAATGAAGTCCATTAGCAAGCGCAAAATCTCTCagcagaaagagaagaaagctACTCAGATGTTGGCTATTGTGCTCGGTGTGTTCATTATATGCTGGCTGCCgttcttcatcacacacataaTGAATACGTACTGTCACGTCCCTGCAGAACTCTACACAGCTTTTACCTGGCTCGGTTACGTCAACAGCGCCGTGAACCCCATCATATACACCACCTTCAATATTGAATTCCGCAAGGCTTTTATTAAGATCCTGCACTGCTGAGAGTGGAATTATCCATAAGTGAAGACAAACACAGCTCATCCACATGTGGCCTACATAAAGCTCCTTCCTGAAGACTGTTTTAAAAGGGAGCTAAACTTGAAGGAGATTACTGGGAATGACACGGATGTACATATGAAGTTGAAGATGTATTATAAAAGCAAGCAATTCTCCCAGTGTCATCTCATGCAACAGTAAGACATTTCTGGATAATTCCTAAGGAGGTGTCATTCAGTATAAGCTTCACAGTATtacttttgtttattaattacacaataaaggTAAAGTAAACATCATTTAGATTATAATACTGCAGTCTTCATAGTGGTGGTAACATACAGCAGTGTAATATgcagcaacagtaagaaaattTTAATACACTAATGCAAGTGTTGATGCTCAGCTGACAAcaaattacatatatacatgtgtgtataaaagtaATATGCACAAGAacaaaaagtgctttttttgaaaataatattgAGGAAATATTGATCCTCATAAACATGGTGGTGCTGTGCATTTTGGTCTCAGCTATCACTATCAAGACGCATTCAATCACTGTAGCTTGATGATTGATGATTTGGTCTTTAGGGTCAAACTGATCCCATGAGAAATTTGTACTAAGTGCAATTTGGTTGGAGTTTGTTAAATTTCATATGAACGAAATCATAAGAAAAGGTACAAATGGTAACCATAACTCAAACTTTGGTGAATGGAGTGTGAGAGGAAAACACCACTCAAGATCATTAAACCAGTTTGCAAAAATTTTGTCACAAAATGACTGTGCAATTATAA
>XM_034310395.1
ATGAAGACAACACGATAGGGACACTGTTCCACTCATTAACAGCTTTTCATCTCTCTGCTGACAATCTGCTAGAGACATTTTCGAGCAACTGAAACTTGAGGAACTCAAGGACTTGGTTTGAATACATCAGTCTTACAAAGAAGGGCCTCTTCTTGGCCTCGGACCCTCACAGCTGATGGAAGTCTTGGAGGAGTATGCTTACAATGAAAGCTTCCTCAAAAATGGATTCAATGGCCTCAACACTACAGATGGAGGCAGAAGACATCAGTACAATTATTATGCCATGCTACTCACTCTGCTCATTTTCGTCATCGTCTTCGGAAACGTACTCGTGTGCATGGCTGTGTCAAGAGAGAAAGCTCTACAGACCACTACTAACTACCTGATCGTGAGCTTGGCTGTCGCTGACCTGCTGGTGGCGACTCTGGTTATGCCTTGGGTGGTATATCTTGAGgtggtGGGAGAATGGAGGTTTAGCACAATCCACTGTGACATCTTTGTCACTCTTGATGTTATGATGTGCACAGCAAGCATCCTTAATCTTTGTGCCATTAGCATTGATAGGTATACAGCAGTTGCCATGCCAATGTTGTATAATACACGCTACAGCTCCAAGAGGAGAGTCACAGTCATGATCTCAGTAGTGTGGATCCTGTCCTTTGCCATTTCATGCCCCCTGCTGTTTGGACTCAATAACACAGAGAGCCACAATGAAGCCATGTGTGTAATCGCGAACCCTGCCTTTGTAGTCTACTCGTCTGTTGTGTCCTTCTATGTACCCTTCATCATCACCCTGCTCGTATACGTGCAGATCTACGTAGTGCTGCGTAGACGGCGGAAACGTGTTAGCACAAAGCGCACGTACCCAAGCAGCAACATGGACATGGGTGCTTTGAAGAAATGCACTCACCCTGATGATGTGAAGCTGTGCACGGTCGCTGTGAAGTCCAATGGGAATTTCCCTGTTAATAACAAAAATGTTTTCATAAAGGAGGTGGcaaacaatgaaaatgaaagccAAATGGATGAAATCACAAACCTTAATCCTCCAAACCAGAGGACACTTCAGCAGACAGGTGAGAGTCAGCATGGGCTTCTGCTTGGTTCGAACCACAGTGAAATAGATACAGCACCCTCCGCTCCTGAGCTCAAGCCAACAAGGAACGGAAAGACCTACGACGCCTCCAAAATGGCTAAAGCATTTGAGACTCAGGTGTCTCCCAGTGGCAAAATGCAGACATCAATGAAGTCCATTAGCAAGCGCAAAATCTCTCagcagaaagagaagaaagctACTCAGATGTTGGCTATTGTGCTCGGTGTGTTCATTATATGCTGGCTGCCgttcttcatcacacacataaTGAATACGTACTGTCACGTCCCTGCAGAACTCTACACAGCTTTTACCTGGCTCGGTTACGTCAACAGCGCCGTGAACCCCATCATATACACCACCTTCAATATTGAATTCCGCAAGGCTTTTATTAAGATCCTGCACTGCTGAGAGTGGAATTATCCATAAGTGAAGACAAACACAGCTCATCCACATGTGGCCTACATAAAGCTCCTTCCTGAAGACTGTTTTAAAAGGGAGCTAAACTTGAAGGAGATTACTGGGAATGACACGGATGTACATATGAAGTTGAAGATGTATTATAAAAGCAAGCAATTCTCCCAGTGTCATCTCATGCAACAGTAAGACATTTCTGGATAATTCCTAAGGAGGTGTCATTCAGTATAAGCTTCACAGTATtacttttgtttattaattacacaataaaggTAAAGTAAACATCATTTAGATTATAATACTGCAGTCTTCATAGTGGTGGTAACATACAGCAGTGTAATATgcagcaacagtaagaaaattTTAATACACTAATGCAAGTGTTGATGCTCAGCTGACAAcaaattacatatatacatgtgtgtataaaagtaATATGCACAAGAacaaaaagtgctttttttgaaaataatattgAGGAAATATTGATCCTCATAAACATGGTGGTGCTGTGCATTTTGGTCTCAGCTATCACTATCAAGACGCATTCAATCACTGTAGCTTGATGATTGATGATTTGGTCTTTAGGGTCAAACTGATCCCATGAGAAATTTGTACTAAGTGCAATTTGGTTGGAGTTTGTTAAATTTCATATGAACGAAATCATAAGAAAAGGTACAAATGGTAACCATAACTCAAACTTTGGTGAATGGAGTGTGAGAGGAAAACACCACTCAAGATCATTAAACCAGTTTGCAAAAATTTTGTCACAAAATGACTGTGCAATTATAA

Function


symbol description
drd2 Enables dopamine neurotransmitter receptor activity, coupled via Gi/Go and identical protein binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; arachidonic acid secretion; and negative regulation of transport. Acts upstream of or within phospholipase C-activating dopamine receptor signaling pathway. Located in ciliary membrane and non-motile cilium. Is integral component of plasma membrane. Implicated in several diseases, including end stage renal disease; mental depression; migraine with aura; obesity; and type 2 diabetes mellitus. Biomarker of Alzheimer's disease and schizophrenia.

NR:

description
D(2) dopamine receptor isoform X1

GO:

id name namespace
GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway biological_process
GO:0071875 adrenergic receptor signaling pathway biological_process
GO:0007268 chemical synaptic transmission biological_process
GO:0005887 integral component of plasma membrane cellular_component
GO:0004935 adrenergic receptor activity molecular_function
GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go molecular_function

KEGG:

id description
K04145 DRD2; dopamine receptor D2

RNA


RNA id representative length rna type GC content exon number start site end site
XM_034310393.1 True 2493 mRNA 0.43 8 8729942 8748249
XM_034310394.1 False 2201 mRNA 0.42 8 8729942 8757781
XM_034310395.1 False 2305 mRNA 0.42 8 8729942 8772841

Neighbor


gene id symbol gene type direction distance location
zgc:162608 LOC108277432 coding downstream 82704 8645643 ~ 8647238 (-)
laynb LOC108277700 coding downstream 99788 8615437 ~ 8630154 (-)
sik2b LOC108277697,LOC108436519,LOC107657230 coding downstream 116518 8563170 ~ 8613424 (-)
il4i1 il4i1 coding downstream 217740 8502694 ~ 8512202 (-)
sdhdb sdhd,LOC107709126,LOC107670952,LOC107657257,LOC107586238,LOC107601715 coding downstream 231473 8491788 ~ 8498469 (-)
scn3b scn3b coding upstream 2305 8775146 ~ 8796028 (-)
LOC113532830 LOC108277452,LOC107578747 coding upstream 26626 8799467 ~ 8814548 (-)
mcamb mcam coding upstream 760209 9533050 ~ 9567354 (-)
c1qtnf5 c1qtnf5,LOC107690457,LOC107601727 coding upstream 812803 9585644 ~ 9589292 (-)
kmt2a kmt2a coding upstream 822113 9594954 ~ 9635702 (-)
G222610 ppp2r1b,LOC108277698,LOC104918016,LOC106612458 non-coding downstream 181568 8544912 ~ 8548374 (-)
G222591 NA non-coding downstream 238658 8464576 ~ 8491284 (-)
G222522 NA non-coding downstream 487766 8241064 ~ 8242176 (-)
G222391 NA non-coding downstream 532735 8196805 ~ 8197207 (-)
G222377 NA non-coding downstream 567094 8162633 ~ 8162848 (-)
G222852 NA non-coding upstream 264639 9037480 ~ 9043751 (-)
LOC117599042 NA non-coding upstream 985317 9758158 ~ 9758966 (-)
LOC117599044 NA non-coding upstream 1029651 9802492 ~ 9806509 (-)
LOC117599021 NA non-coding upstream 1114175 9887016 ~ 9895761 (-)
G223353 NA non-coding upstream 1158515 9931356 ~ 9978560 (-)
sorl1 sorl1,LOC107717255 other downstream 251030 8404829 ~ 8478912 (-)
zgc:77784 LOC108277423 other downstream 1266443 7392415 ~ 7463499 (-)
LOC113532805 NA other downstream 2076524 6619172 ~ 6653418 (-)
dynll2a dynll2a,LOC107554284 other downstream 2705589 6021145 ~ 6024353 (-)
LOC113532612 LOC108277970 other downstream 2925969 5797928 ~ 5803973 (-)
G222809 oaf other upstream 168177 8941018 ~ 8946899 (-)
LOC113532707 LOC108277821,LOC108277480,LOC108277820,LOC108277479,LOC108277478 other upstream 904418 9677259 ~ 9713059 (-)
LOC113533081 LOC108277503,LOC108425821,LOC103022652 other upstream 1535209 10308050 ~ 10312516 (-)
appbp2 appbp2 other upstream 1935411 10708252 ~ 10721333 (-)
aipl1 aipl1,LOC106612843 other upstream 2415409 11188250 ~ 11220656 (-)

Expression



Co-expression Network