zgc:114200 (aph1a,LOC108427283,LOC100304952,LOC107572194,LOC107670051)



Basic Information


Item Value
gene id zgc:114200
gene name aph1a,LOC108427283,LOC100304952,LOC107572194,LOC107670051
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information


Item Value
chromosome id NC_047611.1
NCBI id CM018557.1
chromosome length 24879021
location 16538769 ~ 16552518 (+)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence


>XM_026941568.2
GGCCGAGTGAAGGGTTGGTGTGATTGGAACGAGGCCCAGTGCTGCTGGCGTGGAAAACCCGGAAGTACAAAGCAAATAATCTGACAAACAAAAGCCTCAGGAAGTCGCATGCTTTGCTACGAGAAAAAAGGGGAATTCAAGGGTTTGAAGATGGCACACAAGAAAAAGTGGATATAAAATCGGCGTTAAGTGACATTAAATCAAACTAAAACACTATTAGTCGCAGGTTTACTCCTCAGTCCGTTAGCAGCACTGCTGGTGTAGCCGTGGTGGGGTTCCTAGCAGCCGgtgaaatgacatttttcttgcATGTGTGCTTTCTTTGTTCTGTTTAAGGGAAGTTTAGCAATCATCATCTGTCGAGGCGTTTACTTGGAGTCGAAAAACTTCAACCCAAGACTTTAGGTGTTTAAAAAGCCCTCACATCTCGGCTTGTAGTGCTAACCCGCTAGCTGGAAGTTTGTTGATTAGAATGACTGTGGCGGTGTTTTTCGGTTGTGCTTTTATAGCATTTGGCCCTGCTTTCGccctttttcttttcaccatCGCCAGAGATCCACTGCGAGTCATCATCCTGATCGCGGGtgctttCTTCTGGCTCCTGTCCCTCCTGTTATCCTCTCTGGTTTGGTTCATTGCTGTGAAAGCTAGCAATGTAGACGATGCCAAGGTACAGAAGGGTCTGCTGGTATTCGGGGTCGTGTTCTCAGTCCTCCTTCAGGAGGTTTTCCGATTTGCCTACTATAGACTGCTCAGGAAGGCTAATGAAGGCCTGGCAGCTATTAGCGATGAAGAAGCTTCACCCATTTCCGTCCGGCAAATGGCTTATGTGGCAGGGCTCGGCTTTGGGATAATAAGCGGGGCTTTCTCCATGATCAACATCCTATCTGACTCTCTGGGCCCAGGTACTGTGGGCATCTTTGGAGACTCTCAGTACTATTTTATCACCTCAGCTCTGATGACTCTGGCCATAACATTGCTGCACACGTTCTGGGGTGTGGTGTTCTTCGAGGGTTGTGAGAAGAGCCGCTGGTGGGTCATCGCTGTGGTGGTGTGTCTCCATCTGCTGGTCTCCAGTCTGTCTCTGATGAACCCGCTGTACGAAGGCAGTCTGCCTCCTGTGTATGTTGTAACGGCAGCCATGGCTGTGTGGGCGTTCTTCTCTTCAGGAGGGTCTCTGAACAACCTCTCCCAGCTCTGCACGCGTAAGAGGACCGAGGCAGCGTCTTCGTAAGGCAGCAAAGTCCTGACCTCACAGCAAGACGCAGGCAGTTTATTGGAAGGCTGCATTCACTGCTCGAAGTAACAGAAGCAGCTGGAGCAAGAACAGTAGCAGTGGCCTTCTGTTCTGATGATGGCTCTGGGGTTGAACTCGAACCCCCACCAACAGGGCTGCCTTACAGGTTATAGGACTCTCAGATCATGCTCAGTGTAAATAGCTTGACATCTGTACACACATAGGAATCCATGCTTTTAATGAATTTCTTTGATCGCAAGCATTTCAGAGTAGTATTTTACATATaacacagtgttgttttttttttgttttttttttgttaaatcatGAATGCTACTTTTCGTATTTTCTCTGGtaaaactgtaatgtaaatattaaaagtaagcCTTAGGAGgacaattttgttttaaaatcagAGGTAGGAGAGATGGCCTGGGGCCAGACTATGTCTTCCTTACAATCTGGATTTGTCCcatttaaactgtaaaactgGACTGGGAATAGTTCAAAAGGCAAACTGCAAACACTGAACCTGAAGAAAATAACTCTAATGTTGCCTCGAGCCAAATATGATGGACAGAGATAAGGTGCAACATTCTTCTAAATGTGAAATTTACAAAGTTATTCCTATGcctaaaaacatgacattttttgaGTCATACTACTATGTTTTGCATTTGTACTGCAGTAAACTAAACACATTTAGCCATGATTGACTGCATGGTGAAAAAACTGCCACCTAGTTTGTGGAATGATAATGAATCCAGACTTTAAAGCCGAACCAAAGCCATTGGTCTGACACAGTCTGGTCCCAGGCAAATGTCGAGACGTTTCAGCTGCTAATGCACCCCCTTAATAACACAGCACAAACCACAGTGGATCAGGATCAACAGTTCATTGATTTCCATTTCACACATTTAGCACTGAATATTTTCAGTGAGCCCTTTGAGCAGAGAACCTGATGCATTTGCTCTCATCAAACACCACATGGACAGAAATCCTCCGTCTGATGAGTTCTACATTGGGGCACACGTATGCAATGTGAATGTTCAAAGTGTATGTCCTCAGAGGCAGTCCACTGGCAAATATGTCGAATCAtctactgtgtatatatactaaTTATGCAGAATTAGCTTTGTAATTTGTGTCTCTTACATTGATTCATCAAAAGTTTTCTCTACATGTTCCTCAACTTTGAGAGTTCAATTAACAAGTCCGTCTAGATCGCCGGTCAGTAGAAGTCAGGAACACAGGTCCTCCTTAATGTAGCAGCGAATTCCCCTGCATCctcttccttttatttttcccGGTTTCTCTACTAACAGACTGTTGAGGGCTTCATTTTTAAGATCTCTCAAACTTTTATCTTGTGTAACTGGGTACAAACTTTCCTGTAGACAACAAGCAATATAACAGCTCTTTCTAGCGTTTGGTTCTACCGCTTCAAACACTGGTGCTGGCTTGTGTTATTTCAGGAGACATTCTTTAATTGTGTTTTCATTTCCATGAAATGTTCACTCTGTCATGGATGaacaagtgctttttttttacgCCCATATGGTTATTTAACCAACATAATGCTGCTTTGCTCTTTGTGAGATTATTTGTTTGAAACTGTTTGACTTTCCGCTGGTTTTGATTCGCCGCTCAAAGAACAGTTTCCAGACCAGCACACTGATAACGCATGTCCATAATCACATCCGTCATGATTGTAATATAAATCTGTGCCAGGTAAAgagatggttttttttgtttgttagtttgtttgtttttagtagAACCATTCATTAAGGTACATTATGGGCCTGAGCGGATGTTAGTGGTTGATTTCTCCAGTTTTATTTTGGCACAGCCATTTTGTACCTGGCTAACTGGTACCACATCATACAACCTCTGTCTCAGGACTCACTGTGTGATTAAGAACAAGCAACCTGATGTTCTGGACTAGTCCAAGGCAGCTTCATCTTTCTGAGGCACAGCTGGATTTTTATAGCTACCTAGAACATATCATCTCTTTGGGCATTTCTCTGTCCTAAATAAAATGCCACCTTCAGTATGCACCAAGTTCTGCAGAAGAATATGCTTCTGTTGTGGTTTATTTCACTCCGTTATCTACTCGTCTTTAAGACTACCATGATAAGCGACCTTGTTTGAACCTtgtaaatgaacttttttttttttttttttaaacagcagatAGAAAACTTGGTAGAGTTGCAGTGATACTACCTGTGCCTGGGTCATACTACAAGATTTATACAGTCTGTACCTTTCTGtttgctggggtggtacccttaTCTTTTGTACACAGAATACATTTCTTTCATGTAGAAACatgaatatagtgtacctttaaaaaaatacattctacAGGTACAAGGGTAAGGCTAAGTGTACTACCCCAGCGATAAGAAAAGGTGCAGTTTAgtaccttgttttttttgtttttttttctgagagtgtaacaGAAGGGAAAAATATGAGTGTACCCAGATGCAATGAGAGATCGTCTGGATCATCTTTCAGTTATCAATCCTCCCACACTACAAGATTTACCCAGAATAAAACAGCACAAGCTTTCCGATTATACTCAGCCAATGATCCTGACTCTCAGAACTTGGGATTTTGCAAAATTTCTTGTAAACAAACATGACTTCCGATCAAAGTGAACATGACAGAGACCAATTGTGCTTGGTTGCCATTGTTATGTTGTAAATGTTGAACATGTTTATTATTGAAAATTTGGATTTAACATACCCTATACCACAGGATAAAATCAGGACACCTTGTGATCATCAGAAGGGGCGACTCAACCTCAAAGTAGGCCTGATTATCCTTTAGCATGGCCCGTCTCCTGGACAGTCTCCTTCTTAATACACACTTCTCTATCCTCTATCATCCTGCATTGAACTTACGCTGCATTCAACTTAGCTTGGAAGTGGGAAGCTGGAGCTctgatttaaataattttcaacCGCATTTGAGCTGcacagtgggggaaaaaaaagggtgcctccatgtttgtcttttgttgcaACAATCTAGCCAGCGAACAGTGATGAgaaatttaacaagctaatatgtctgtGGTGATCAATTTAAATCAAATACTAGTAGATACAGTATAATtcaattaaaagaaagaagtaatactttgtttactgttgatgctgttaCTTGCTGAACTTGGAATTGACAAGACCTTCCCCACTTTccaagtaggaattctgagttgaagaggctttttctttggtttttcctagtcagaggttGGAAATTCCCAATTACAAGTTTTAGTTGACTGCAGCAATAATCACAACCGGTGCTCACCAGGATTTTGGACAGACTATGACAAATGGCATTGACATTTTATGCTGCTTTATAAAGTTTCAATGATTAGAATGTAACAAACAGGAAAACTCTTAATGTTAGAAACTCTTTCATCTTGggttaataaaaatgcagtgtagtggtgaaatgaaaatta

Function


symbol description
aph1a Enables endopeptidase activator activity and protein-macromolecule adaptor activity. Involved in several processes, including Notch receptor processing; amyloid-beta formation; and proteolysis. Located in Golgi apparatus and endoplasmic reticulum. Is integral component of plasma membrane. Part of gamma-secretase complex.

NR:

description
gamma-secretase subunit Aph-1b-like

GO:

id name namespace
GO:0016485 protein processing biological_process
GO:0043085 positive regulation of catalytic activity biological_process
GO:0016021 integral component of membrane cellular_component

KEGG: NA

RNA


RNA id representative length rna type GC content exon number start site end site
XM_026941568.2 True 4724 mRNA 0.41 7 16538769 16552518

Neighbor


gene id symbol gene type direction distance location
tpm2 tpm2,LOC108276716,LOC108427282,LOC103044350,LOC107102752,LOC102218310,LOC103389160,LOC107670037,LOC108242564,LOC106571564,LOC107572193,LOC107394912,LOC107737084,LOC105894628 coding upstream 3826 16511235 ~ 16534943 (+)
tln1 tln1 coding upstream 31133 16433574 ~ 16507636 (+)
hmgcs1 hmgcs1,LOC108277226,LOC108427280,LOC107715876 coding upstream 109546 16420040 ~ 16429223 (+)
map3k1 map3k1 coding upstream 120996 16378393 ~ 16417773 (+)
LOC113543581 NA coding upstream 228463 16299094 ~ 16310306 (+)
reep5 reep5,LOC108246451 coding downstream 30518 16583036 ~ 16589994 (+)
LOC113543669 LOC108276552 coding downstream 39375 16591893 ~ 16594397 (+)
trnam-cau_35 NA coding downstream 72391 16624909 ~ 16624980 (+)
trnar-ccu_8 NA coding downstream 72882 16625400 ~ 16625472 (+)
trnam-cau_36 NA coding downstream 72964 16625482 ~ 16625553 (+)
G270525 NA non-coding upstream 28022 16510543 ~ 16510747 (+)
G270520 NA non-coding upstream 152837 16385030 ~ 16385932 (+)
LOC117599337 NA non-coding upstream 174027 16327619 ~ 16364742 (+)
G270536 dcp2,LOC107564107,LOC107702577 non-coding downstream 23845 16576363 ~ 16577240 (+)
G270626 NA non-coding downstream 73466 16625984 ~ 16626358 (+)
G270716 NA non-coding downstream 245327 16797845 ~ 16798435 (+)
G270833 NA non-coding downstream 508463 17060981 ~ 17078555 (+)
G270856 NA non-coding downstream 534877 17087395 ~ 17087922 (+)
vps36 vps36,LOC107701118 other upstream 1767696 14762313 ~ 14771073 (+)
scaf4a scaf4,LOC107555128 other upstream 5656504 10865612 ~ 10882265 (+)
G266868 LOC108276566 other upstream 5968064 10569028 ~ 10570705 (+)
dclk1a dclk1,LOC107728871,LOC107577778 other upstream 6776072 9704360 ~ 9762697 (+)
LOC113543674 NA other upstream 7113914 9419665 ~ 9424855 (+)
trnar-ccu_11 NA other downstream 535150 17087668 ~ 17087740 (+)
trnam-cau_40 NA other downstream 535230 17087748 ~ 17087819 (+)
trnar-ccu_12 NA other downstream 535931 17088449 ~ 17088521 (+)
trnam-cau_41 NA other downstream 536011 17088529 ~ 17088600 (+)
trnar-ccu_13 NA other downstream 536709 17089227 ~ 17089299 (+)

Expression



Co-expression Network