manf (manf,LOC107592842,LOC107691893,LOC107750980,LOC106583751)


Basic Information

Item Value
gene id manf
gene name manf,LOC107592842,LOC107691893,LOC107750980,LOC106583751
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047614.1
NCBI id CM018560.1
chromosome length 21552800
location 15375847 ~ 15382948 (+)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026932414.2
CTCGGAGTAGCAACGTTTTCGTGTTCAAGAACCGGTATCCGGACCtttggtgtgtgcgtgtgtctgtctgtgtgtgtctgagagaacGTGCTATACATGTAACGTGTGTTTTAGAAGTTTAAATACAATTTCAGCTATGTTTGGTTTAAGTGGACTTTCGGTGGCTCTTGTTTTCGCTTTAGTGCCGAGCAGTAGCGAGGCTTTAAAAGAGGGAGAGTGTGAAGTATGTTTAAGCTTTCTGGGGAAGTTTTACCAGTCACTACAAGACAATAATGTACAGTTTACCAGTGATGCCATTGAAAAGGCTCTAGTCAAAGCCTGCAAGGATgcgaaaggaaaggaaaatcgATTTTGCTACTATATCGGAGCAACGAGCGACGCTGCTACAAAAATCATTAACGAGGTCTCTAAACCGTTGAGTTACCACGTGCCGGTGGAGAAGGTGTGCGAAAAGCTCAAGAAAAAAGACAGTCAGATCTGCGAACTGAAGTACGATAAACAAGTGGACTTGAGCACAGTGGACCTAAAGAAGCTGAAGGTGAAGGACCTGAAGAAGATTCTGGATGAATGGGGAGAGTCTTGTAAGGGCTGCGCGGAGAAATCAGATTTCATCCGTAAGATCACCGAGCTCATGCCCAAGTACGCCCCGAATGCAGCCAAGGCACGGACAGACCTGTAAACTCTCTGTGGACTTGTGGGACCAAAGGAGCAGCTAAGAGCATCGTGGGTGTGATTTCTGCGCTGATGGGGAGCGTGGTTTTGTTTGTATTGCCTGTTAATCTAGTGGTAAACATGAAGATTGTGAcctttcatccattcattctttTAAGGCACACTGTACTGTCAATATTAGACAACACTGTACTGTTTCAACCCAGAgttcatatataatataatagcaacTCTCCTGAATAACATACACTTTACTTATAGTGTTGACTTGCATAAATGCTTCAGATGCTAACATGGACTTCAAATCAACTGGGTTTAACTGGTTATTAATTCAGAAATGTGATCAAATGTCtgttatacatatatattacacatattatatataaatggaTCCTTTTATTAGATTGTTTAGCAAATGGGGCCAAAGCTTACCAGAAAAAGCTGAGTTTGCACGCAGGTGTGCAGCGATAATGATTCACTAACTTTCATGCAAAACAATCATAATGCAGAAGTCAGCTAAACTTTGAGTTGAAACAGACTACAGAAACTGAAAAGGTTTATACCTAGACATGATGGGTAAGATCACAAACCACTGTCACCCTGTAGTCACCTATAGTTTCTTTTCAAAtggaatagttttttttttatttgtctattaTATGGAAGAGGATGTGGGAGAATCCAAACTGATTCAAGTCACGTTGACGTCACtgtaaaacatgtttattaagGTTGTACtatactttttcattaaaataagaaaatggc

Function

symbol description
manf Predicted to enable growth factor activity. Acts upstream of or within dopaminergic neuron differentiation. Predicted to be located in extracellular region. Predicted to be active in endoplasmic reticulum and extracellular space. Is expressed in several structures, including axis; brain; hatching gland; pleuroperitoneal region; and sensory system. Human ortholog(s) of this gene implicated in Parkinsonism; breast cancer; carcinoma (multiple); and pancreatic cancer. Orthologous to human MANF (mesencephalic astrocyte derived neurotrophic factor).

NR:

description
mesencephalic astrocyte-derived neurotrophic factor isoform X1

GO:

id name namespace
GO:0071542 dopaminergic neuron differentiation biological_process

KEGG:

id description
K22556 MANF, ARMET; mesencephalic astrocyte-derived neurotrophic factor

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026932414.2 True 1440 mRNA 0.40 4 15375847 15382948

Neighbor

gene id symbol gene type direction distance location
dock3 dock3 coding upstream 7717 15138351 ~ 15368130 (+)
si:dkey-49n23.1 si:dkey-49n23.1,LOC108255172,LOC108436691,LOC107719940,LOC107571036 coding upstream 249449 15064877 ~ 15126398 (+)
ssuh2.1 LOC108255262,LOC108436692 coding upstream 313847 15045544 ~ 15062000 (+)
LOC113538136 LOC108255245 coding upstream 335713 15029134 ~ 15040134 (+)
cand2 cand2,LOC107557972,LOC107691187,LOC107719941,LOC107720354,LOC107657311 coding upstream 352173 15012865 ~ 15023674 (+)
rbm15b rbm15b coding downstream 2346 15385294 ~ 15389128 (+)
nicn1 nicn1 coding downstream 480508 15863456 ~ 15877266 (+)
ccdc66 NA coding downstream 1289872 16672820 ~ 16687543 (+)
atp6ap1la atp6ap1l,LOC108254970,LOC107680564 coding downstream 1499054 16882002 ~ 16891308 (+)
pde12 pde12 coding downstream 1510283 16893231 ~ 16897114 (+)
G308018 NA non-coding upstream 575705 14798973 ~ 14800142 (+)
G307997 NA non-coding upstream 595089 14699997 ~ 14780758 (+)
LOC113537908 NA non-coding upstream 612673 14760831 ~ 14763174 (+)
G307976 NA non-coding upstream 777235 14598393 ~ 14598612 (+)
G307971 NA non-coding upstream 786615 14589025 ~ 14589232 (+)
LOC113537967 NA non-coding downstream 10661 15393609 ~ 15407641 (+)
G308404 NA non-coding downstream 29151 15412099 ~ 15413822 (+)
G308707 NA non-coding downstream 491057 15874005 ~ 15875206 (+)
G308737 LOC105913228,LOC107592839,LOC107701594,LOC108431596,LOC107691887,LOC100331190 non-coding downstream 610447 15993395 ~ 15994043 (+)
G308758 LOC108280992,LOC108431596,LOC107756932,LOC107592839 non-coding downstream 638268 16021216 ~ 16022142 (+)
gpd1b gpd1,gpd1b,LOC107698578,LOC107727040,LOC107721242,LOC107694423 other upstream 850871 14514592 ~ 14524976 (+)
asic1b asic1,asic1b,LOC107721241,LOC107569540 other upstream 899030 14179783 ~ 14476817 (+)
ippk ippk,LOC107755999,LOC106566243 other upstream 1682935 13674354 ~ 13692912 (+)
G306480 tuba1c,LOC103148207,LOC106920718,LOC102311436,LOC101065103 other upstream 2913311 12457601 ~ 12462536 (+)
G306103 NA other upstream 3860034 11515059 ~ 11515813 (+)
dag1 dag1,LOC107757307,LOC107592827,LOC108415278,LOC108415277 other downstream 373942 15756890 ~ 15799890 (+)
amigo3 amigo3 other downstream 1106413 16489361 ~ 16501684 (+)
LOC113537865 LOC108280979 other downstream 1878031 17260979 ~ 17263663 (+)
snrpe snrpe other downstream 3304449 18687397 ~ 18692014 (+)
G310681 LOC108254836 other downstream 3704077 19087025 ~ 19087806 (+)

Expression


Co-expression Network