pparda (ppard,ppardb,LOC108281076)



Basic Information


Item Value
gene id pparda
gene name ppard,ppardb,LOC108281076
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information


Item Value
chromosome id NC_047614.1
NCBI id CM018560.1
chromosome length 21552800
location 282867 ~ 295160 (+)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence


>XM_034314382.1
AGTTAAAGCTGCAGAGACGCAGAGCGCATCAGTCTGCAGATCCTCCACTTTCCTCCACTTTCCTCCACTTTCCTTCTGCTTTCCTTCTGCTTTCCTCCACTTTCCTCTGCTTTCCTTCTGCCCTGTAACTCTGCTGAGGAGAAACAACCCGCTTTAACactttccttcattcatttcacttttcttctggggttttctgtttgtgttcagtggcAGCGGAGACAAAGTGAAAAACTAACAAACCTGACACACGGAGGactgggactgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtggaattagACATGATGgtggataaacacacacactcctgatcCACACAGCAGGTTCGTCCTGGTCATGCGGACATCGAGGACGTTCTGCCATGGAAGGCACTGAGTCGGCCATTTTAGCAATGAAGAACAGGAAGTCGGTGGAGGTGGACAGAGCTTCCTCCCCTtgcagaagccacgcctccccGAAAGCGGGTCCAGAGGAGGAGGGTTTTGAGAAGGTGCTGTCAGAGCTGAGTGCTGCTGCAAATTTGAATGTGGAGGCGGAGCTGGGTGTGGAGGCGGGATTTGAGGAGACGCCAGACTGGGGGCGGGGCTGTGAGGAAGGAGATGCAGCAGATGAGGTGGAACCTGAGAACAGCAATGGCAGCATGACTGAGTTCCAAAATCCTGCTCCATCTACAGatgtgtcgCACACTCCGTTGTCAGAGCAGCTCCTGTTGGGTCGTGATGACGTGAAGGTGGTTAATGTGGAGTGTCGGATCTGTGGAGATCAAGCATCAGGATTTCATTATGGAGTGCACGCCTGCGAAGGGTGTAAGGGTTTTTTCCGCCGCACGGTGAGAATGAAACTCGAGTATGATAAATGTGAACGCAGCTGCAAGATCCACAAGAAAAACCGCAACAAGTGTCAGTACTGCCGCTTCCAGAAGTGTCTGATGCTCGGTATGAGTCACGATGcgatTCGGTACGGCCGCATGCCTGAGGCGGAGAAGAGGAAGTTGGTGGAGGGAATGTTATCAGACAGTCGGACAGCGAGCAGCTCCAACCTGAAATCTCTGGCTAAAAAAGTGTACAATGCGTATCTGAAACACCTGAACATGACCAAGAGGAAAGCACGCAGCATCCTGACAGGAAGAACCACCTCCAACCctTTTGTGATCTATGACCTGGGCTCTCTGTGGCGTGCGGAGAGCGGGATGGTGTGGGACAGCGGGGTTCTGAGTGGACGAGCGCAGAAGGAGATCGGCGTTCACGTCTTCTACCGCTGTCAGTGCAGCACCGTGGAGACTGTACGACAAATCACCGAGTTCTCCAAGTGCATCCCGGGATTCATCGACCTGTACCTCAACGACCagGTGACGCTGCTGAAGTACGGTGTTCACGAAGCGATCTTCGCCATGCTGCCATCTCTGATGAATAAGGACGGGTTGCTAGTGGCGAATGGGCGGGGCTTCGTCACGCGTGAGTTCCTGCGCAGTCTCAGGAAGCCGTTCAGTGAAATCATGGAGCCGAAGTTCGAGTTTGCTCTCAAGTTCAACGCGCTGGAGCTGGACGACAGTGACCTCGCGCTGTTCGTTGCCGCCATCATCCTGTGTGGAGatcGTCCTGGGCTGATGAACGTGAAGCAGGTGGAGGAGATTCAGGATAAGATCCTGCAGGCGTTGGATCAgcacctgcagcacacacaccccGACGCCGCGTacattttccccaaactgctgcagAAACTGGCAGACCTGCGACAGCTCGTCACTGAGAATGCACAGCTCGTCCAGATGATCAAAAAAACTGAGTCTGAGACCTCACTGCACCCTCTACTGCAAGAGATCTACAGAGACATGTACtgaacgcacacacactcacacacacactcacacacacacacacacacacacactcacacacacacacacacacactcacactcacacacacacacacacacacacacacacacacacacacacacactcacacacacacacacatcagcagaaCAGCTGTGCTGAATCACAGTGTGATAAAAGAATCACAGACGAATCGGTTTCAGAACGACTCATTTAAATGAACGAGGAAATTCATTGGATTTGGAAGCAGGATTCAATCCAtagagtttatatttatttttatttgtttttttttctgtgtatgtttattaatgttagaaactatttaataatgtacataTTCAGAGGATTTAACAAGGTTTAAGTGATGAATCAGATGAATCGAATGAATCGAAATGTAATTAACTGTAATGGGTTATTTAAAGAGAATCTAATCAGTAAAGTGAGTCATAATGTCCATaactgaatcacacacacacacacacacacacacacacacacacacacacacgcatcgcacacacacacacaca
>XM_034314383.1
CGCTCCTCACTTCTCCGTTTAACTGAAATCTCTTCGTCTTTCCTCTTTCACACATCCTGAAAATCTGCATGTAAAATCCATCACATTCCCTTTTCATCCCAAACCGCTCTTCTGGTTATTCCACACTGAAATCCAATCCCAACTCTCCCGTCTCACTCCGTCTCACTCCGTCTCACTCCGTCTCACTCCGTCCTGCACCCAGAGCCTGGTGTCTCGTCCCCACGTCTCGTCTGAAGCTCCCTCCATCACTGCAGCTCACATCCCGTCCTCAGCACCTCGCCTCGTCCCGCTCCGCTTCCTCCTGCTCGATCCGAACGCAGCTGAACCAACTTTCAGTTCTGTAGTGAGATTTATTGTTTCTTGAATTGGCCAATCGCAGGAAAGACGCAGGGAGTCTGTTCGTCCTGGTCATGCGGACATCGAGGACGTTCTGCCATGGAAGGCACTGAGTCGGCCATTTTAGCAATGAAGAACAGGAAGTCGGTGGAGGTGGACAGAGCTTCCTCCCCTtgcagaagccacgcctccccGAAAGCGGGTCCAGAGGAGGAGGGTTTTGAGAAGGTGCTGTCAGAGCTGAGTGCTGCTGCAAATTTGAATGTGGAGGCGGAGCTGGGTGTGGAGGCGGGATTTGAGGAGACGCCAGACTGGGGGCGGGGCTGTGAGGAAGGAGATGCAGCAGATGAGGTGGAACCTGAGAACAGCAATGGCAGCATGACTGAGTTCCAAAATCCTGCTCCATCTACAGatgtgtcgCACACTCCGTTGTCAGAGCAGCTCCTGTTGGGTCGTGATGACGTGAAGGTGGTTAATGTGGAGTGTCGGATCTGTGGAGATCAAGCATCAGGATTTCATTATGGAGTGCACGCCTGCGAAGGGTGTAAGGGTTTTTTCCGCCGCACGGTGAGAATGAAACTCGAGTATGATAAATGTGAACGCAGCTGCAAGATCCACAAGAAAAACCGCAACAAGTGTCAGTACTGCCGCTTCCAGAAGTGTCTGATGCTCGGTATGAGTCACGATGcgatTCGGTACGGCCGCATGCCTGAGGCGGAGAAGAGGAAGTTGGTGGAGGGAATGTTATCAGACAGTCGGACAGCGAGCAGCTCCAACCTGAAATCTCTGGCTAAAAAAGTGTACAATGCGTATCTGAAACACCTGAACATGACCAAGAGGAAAGCACGCAGCATCCTGACAGGAAGAACCACCTCCAACCctTTTGTGATCTATGACCTGGGCTCTCTGTGGCGTGCGGAGAGCGGGATGGTGTGGGACAGCGGGGTTCTGAGTGGACGAGCGCAGAAGGAGATCGGCGTTCACGTCTTCTACCGCTGTCAGTGCAGCACCGTGGAGACTGTACGACAAATCACCGAGTTCTCCAAGTGCATCCCGGGATTCATCGACCTGTACCTCAACGACCagGTGACGCTGCTGAAGTACGGTGTTCACGAAGCGATCTTCGCCATGCTGCCATCTCTGATGAATAAGGACGGGTTGCTAGTGGCGAATGGGCGGGGCTTCGTCACGCGTGAGTTCCTGCGCAGTCTCAGGAAGCCGTTCAGTGAAATCATGGAGCCGAAGTTCGAGTTTGCTCTCAAGTTCAACGCGCTGGAGCTGGACGACAGTGACCTCGCGCTGTTCGTTGCCGCCATCATCCTGTGTGGAGatcGTCCTGGGCTGATGAACGTGAAGCAGGTGGAGGAGATTCAGGATAAGATCCTGCAGGCGTTGGATCAgcacctgcagcacacacaccccGACGCCGCGTacattttccccaaactgctgcagAAACTGGCAGACCTGCGACAGCTCGTCACTGAGAATGCACAGCTCGTCCAGATGATCAAAAAAACTGAGTCTGAGACCTCACTGCACCCTCTACTGCAAGAGATCTACAGAGACATGTACtgaacgcacacacactcacacacacactcacacacacacacacacacacacactcacacacacacacacacacactcacactcacacacacacacacacacacacacacacacacacacacacacactcacacacacacacacatcagcagaaCAGCTGTGCTGAATCACAGTGTGATAAAAGAATCACAGACGAATCGGTTTCAGAACGACTCATTTAAATGAACGAGGAAATTCATTGGATTTGGAAGCAGGATTCAATCCAtagagtttatatttatttttatttgtttttttttctgtgtatgtttattaatgttagaaactatttaataatgtacataTTCAGAGGATTTAACAAGGTTTAAGTGATGAATCAGATGAATCGAATGAATCGAAATGTAATTAACTGTAATGGGTTATTTAAAGAGAATCTAATCAGTAAAGTGAGTCATAATGTCCATaactgaatcacacacacacacacacacacacacacacacacacacacacacgcatcgcacacacacacacaca

Function


symbol description
ppardb Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and nuclear receptor activity. Predicted to be involved in several processes, including negative regulation of cholesterol storage; positive regulation of fatty acid metabolic process; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in brain; intestine; liver; and ovary. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human PPARD (peroxisome proliferator activated receptor delta).
ppard Enables several functions, including linoleic acid binding activity; nuclear receptor activity; and transcription coactivator binding activity. Involved in apoptotic signaling pathway and positive regulation of transcription, DNA-templated. Predicted to be located in chromatin. Implicated in type 2 diabetes mellitus. Biomarker of biliary tract cancer and pancreatic cancer.

NR:

description
PREDICTED: peroxisome proliferator-activated receptor delta-like

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0043401 steroid hormone mediated signaling pathway biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0004879 nuclear receptor activity molecular_function
GO:0003707 steroid hormone receptor activity molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG: NA

RNA


RNA id representative length rna type GC content exon number start site end site
XM_034314382.1 False 2408 mRNA 0.50 8 282867 295160
XM_034314383.1 True 2447 mRNA 0.51 8 284346 295160

Neighbor


gene id symbol gene type direction distance location
LOC113525392 stk38,stk38b,LOC105900354,LOC107667630,LOC105016867,LOC108265501 coding upstream 41201 226264 ~ 241666 (+)
wdr77 wdr77 coding downstream 20808 315968 ~ 326307 (+)
zgc:153675 LOC108255011 coding downstream 81402 376562 ~ 380543 (+)
btg2 LOC108255010 coding downstream 110948 406108 ~ 409450 (+)
arl8a arl8a,LOC107671521,LOC107722853,LOC107569762,LOC107750681 coding downstream 136352 431512 ~ 439177 (+)
apobec2a LOC108281085 coding downstream 196885 492045 ~ 495637 (+)
G299528 NA non-coding upstream 28635 251723 ~ 254232 (+)
G299522 NA non-coding upstream 46377 236076 ~ 236490 (+)
G299482 NA non-coding upstream 65458 209994 ~ 217409 (+)
G299486 NA non-coding upstream 77955 203812 ~ 204912 (+)
G299503 NA non-coding upstream 104202 173753 ~ 178665 (+)
G299618 NA non-coding downstream 270116 565276 ~ 565508 (+)
G299625 NA non-coding downstream 306398 601558 ~ 602113 (+)
G299679 NA non-coding downstream 512999 808159 ~ 809350 (+)
G299708 NA non-coding downstream 543203 838363 ~ 838915 (+)
G299695 NA non-coding downstream 550308 845468 ~ 847722 (+)
LOC113525237 LOC108281078 other upstream 93550 165615 ~ 189317 (+)
dram2b NA other downstream 56428 351588 ~ 360258 (+)
cdkn1a cdkn1a other downstream 220380 515540 ~ 520943 (+)
LOC117599902 NA other downstream 383757 678917 ~ 726922 (+)
mfap2 mfap2 other downstream 463349 758509 ~ 805098 (+)
LOC113539702 LOC108281106 other downstream 547693 842853 ~ 844870 (+)

Expression



Co-expression Network