abcb4 (abcb1,abcb4,LOC107549227,LOC107738866,LOC107689873)


Basic Information

Item Value
gene id abcb4
gene name abcb1,abcb4,LOC107549227,LOC107738866,LOC107689873
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047616.1
NCBI id CM018562.1
chromosome length 21037487
location 5332129 ~ 5349833 (-)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026924200.2
TAAAAGCTCGCGCACGCACTGACCGCGCGCTACCTCTCCAAGCTCGTCGACCTGAAAAACGCGCGCGAGCTCTCCGTAAGGAAGCCGCAGAGCTCAAGTTAACATCATTCCTGAACAACAAGCGGCTTCagagaaacaagacaaaaacagacacCATGGGCAAAAAGTACGACTTAAAGAAGGAGGAAAGACAAGGCAGTCCAAATGGAGACATAAGtggggaaaaaaagggaaagaaagaaaagaaagctgcCCCAGAGCCAATGGTGGGACTGCTGGAAATTTTTCGCTTTGCTGATAGTCTGGACATTTTCCTGATGTTGGTTGGAGCCATTATGGCCATGGCCAATGGAGCAGTGCTTCCTGCAATGGTGATTGTATTTGGAGAAATGACTAACAGCTTTGTGGACAACAGTATTTTAGAGAGCCTGTCTCCAAACATGACTGAGAACATGACCTGGCCATTTTCCAATCAAACACTTGGAGAACAGATGACAAGGCATGCCATTTACTACAGCATCATGGGAGGCATAGTCCTTTTTGCAGCCTATATGCAGGTGGCCTTCTGGACCCTGGCTGCAGGGCGACAAGTGAAGAGGCTCAGAAAGATGTTCTTTCACTCCATCCTCAAACAGGACATTGGTTGGTTTGATGTCAATGAGACAGGACAGCTCAACACACGGCTCACAGATGACATCTTTAAGATAAATGAAGGCATTGGAGACAAGCTGGGCACATTAATTCAGTCCATCAGCACCTTTTTAACAGGCTTCATCATTGGCTTTATCAAAGGCTGGAAGCTCACCCTTGTCATCATCTCCATAAGCCCCCTGCTAGGCATCTCAGGTGCTGTCATTACCAAGGTGATGACCTCATTCACGTCGAGGGAGCAGACAGCATATGCGAAAGCTGGAGCTGTAGCTGAAGAGGTGCTGTCTGCCATCAGAACTGTCTTTGCCTTTGGAGGACAGAAGAAGGAACTAaagagGTATCAGAAAAACCTGGAAGAAGCCAAGAACGTTGGTATAAAGAAAGCCATTACAGTAAACATTGCTGTGGGTTTCACATACTTCATGATCTACATCTCCTACGCTCTGTCCTTCTGGTATGGCAGCACGCTGATTTTCGCTGGAGAGTATGACATCGGAACACTCCTGACAGTTTTTTTCGCTGTTGTGATTGGAGCATTCGGCCTTGGCCAGACCTCTCCTAACATTCAAGCGTTTTCTAGCGCACGAGGGGCTGCTCACAAGGTTTTTAACATCATCGATCATAAATCCAGCATCAACAGTTTCTCAGATGAAGGCCACAAACCCGACATGGTCAAAGGAAATATTGAGTTCAAAGACGTTCACTTTAGCTACCCTTCGCGGCAGGATGTGAAAGTCCTAAATGGCGTGAATCTTAAGATCAGCAGTGGACAGACTATTGCTCTTGTAGGGAGCAGCGGTTGTGGTAAAAGTACAACAGTCCAACTGATTCAGCGCTTCTACGACCCCCAAGAAGGAGCAGTGAGTATAGATGGCCATGACATTCGCACTCTGAACGTGCGTTGTCTGAGGGAGATGATCGGCGTTGTGAGTCAGGAGCCCGTTCTTTTTGCCACCACAATTGCCGAGAACATTCGATATGGCCGTGAGGATGTGACGCAGGAGGAGATAGAGCAGGCCACGCGTGAAGCCAATGCTTATGATTTCATCATGAAACTTCCTGATAAATTTGAGACTCTGGTGGGAGACAGAGGCACACAGATGAGTGGAGGACAGAAACAGCGAATTGCCATCGCCCGAGCTCTTGTGCGCAATCCCAAGATCCTCCTGTTGGATGAGGCAACATCAGCTTTGGACACAGAAAGTGAGGCGATTGTACAAGCAGCCCTGGATAAGGTGAGACTTGGCAGGACGACCATCATAGTGGCCCACCGTTTGTCCACTATCCGCAATGCTGACGTCATCGCTGGATTCCAGAACGGGAACATTGTAGAGCTCGGCACACACGATGAACtgatggagagaaagggagtCTACCACTCACTGGTCACTATGCAGACGTTTAAGAGCACAGAAGCCACAGAATTAAAAGCAGAGGAGGCAGGGCTGGATGAGAAGAGCCCCTCTACCACGTCtgtgacagaacacacactctacagaCAGAAATCCAAGAGTTTCATTGGCTCAGAGAAAGGCCAGGAGGATGAACTCAAAGATTCAGCACAGGAGGAAAAGGTCCCAGAAGTGTCATTCTTCAGAGTACTGAGTCTGAATAAGGCAGAATGGCCCTACATGGTGGTGGGCATCTTCTGTGCGATCATCAATGGGGGCCTGCAGCCTGCTTTTGCTGTTATCTTCTCCAAAATCACTGCTgtGTTTGCTGAGGTAAACGAGGACATTAAAAGGGAAAAGGCGAATCTCTTCTCACTGCTGTTTGCTATCATTGGGGTGGTTTCCTTCATCGCTCTTTTCTTACAGGGTTTCTGTTTTGGGAAAGCTGGTGAGATTCTGACCATGAGACTGAGGTACAGAGCCTTTAAATCCATGATGAGACAGgacCTAGGTTGGTATGATGACCCTAAGAATAGTGTGGGAGCACTGACGACCAGACTGGCCACAGACACTGCTCAAGTGCAGGGTGCAACGGGGTTGAGACTGGCCACATTGGCTCAGAATGTGGCCAACCTTGGCACTGCAATCATCATCTCGTTTGTGTACGGCTGGCAGCTCaccctcctcatcctctccaTTGTGCCAGTTATGGCTGTAGCAGGAGCTATTCAAATGAAGTTGTTAGGAGGCCATGCTGCAAAGGACAAGAAGGAGTTAGAGCAAGCTGGAAAGatTGCTACTGAAGCCATAGAAAATATCCGCACAGTCGTATCATTGACCAGAGAGAGGAAGTTTGAGAGTCTTTACCAGCAGAACCTAATTGTTCCATACAAgaatgCTCAGAAGAAGGCACATATCTTTGgctttactttctctttttcccaAGCCATGATCTACTTTGCCTATGCAGGCTGCTTCAAGTTTGGTGCATGGCTCATTGAGCAGAAAATGATGACGTTTGAGGGTGTTTTTCTtgtaatcTCAGCTGTAATATATGGAGCCATGGCAATGGGAGAAGCCAACTCCTTTACTCCAAACTACGCCAAGGCTAAGATGTCGGCCTCCCATATCCTAATGCTCATCAATCGAGTGCCAGATATCGACAATGACTCAGAGAAGGGAGAAAAGCCGGATCACTTCGAAGGGAATGTGCGCTTTCAGGATGTGAAATTTAGATATCCGTCACGGCCAGACGTGCCTGTACTGCAGGGCCTGCGGCTCAGAGTGAAGAAGGGTCAGACCCTTGCTCTGGTGGGCAGCAGCGGCTGTGGCAAGAGTACCACCATACAGCTGCTGGAGAGATTTTACGATCCCCTAGAAGGCACagtgATGCTAGATGATAACAACGTCAAACAGCTAAACATCCACTGGCTGCGCTCTCAGATTGGTATTGTATCCCAAGAGCCTGTGCTATTTGACTGCAGCCTGGCCGAGAACATCGCATACGGAGATAATAGCAGGCAGGTCGCTCAGGAGGAGATCGAACAAGCTGCCAAGGCTGCCAATATACACTCTTTCGTAGAGGGGCTTCCACAGCAATATCAGACTCAGGCAGGTGATAAAGGCACTCAGCTGTCAGGCGGACAGAAGCAGCGCATCGCTATTGCTAGAGCCATCCTGCGCAACCCCAAACTGCTGCTACTGGACGAGGCCACATCGGCTCTTGACACAGAAAGTGAAAAGATCGTGCAAGAAGCCTTGGATAAGGCTCGTGAGGGTCGTACCTGCATCATAGTGGCTCACCGGCTGTCCACCATCAAGAATGCTGATGTTATTGCTGTGTTTCAGAATGGTGTGGTGGTGGAGCAgggcacacacaaacagctccTCAGCCAGCAGGGGGTTTACTACACCCTCGTCAATTCCCAAATGGGTTACAGCAAATAGGCAACTACTTGAGAAGAATGACAGGGAATCAGGATGTTTTATGCAGTATGGAAATTTAACTTTACTGCAAAGAGGAATGGGGTTGATCATAACATTTGAGATGATCTGTTATGTAAGACAGGATTTAGATGAGGTCGtaagatttaatatttaaaagctgTAATAGATGTGGTAGAGGAAAAACCATGGTCACAGTAAGAAAAGTGACATGGACAGAAGACTACTGAAGATGTTAGTACTTTTAAAATAACCTCTGTCTGCTGGACATGTACTCACTTCTAATCTGTAAGTTTATTTAACTATTTCACTCACTCAGTTCAGCTTCATAATCAGTTACAATCCATAATACAACTAAAcgcatttattaaaataacaatttagcCACACACTTCCAATCATAATGACAGGGAGAGATATGGAGTCTGATTTACAGCGAGCCAAAATGTGCCACAGAAGTAATAAGAATCATTGGCTACTTTGTGTTTGGCAAGTTTGAATGTATGTAATTATGactaatacatatttatttaaattaaggaaggtttataaagaaaacaggttttcaaaaataaaaattggttctgaattattattaattcttataattattattaaagttctGTGATGGCACTGTATTGTGTTCTAATAGGGcacaaatgtttttatactggctagctacttttttttggaataaaGTTTCACTTATTTACATTT
>XM_026924201.2
GCTGGGCACATTAATTCAGTCCATCAGCACCTTTTTAACAGGCTTCATCATTGGCTTTATCAAAGGCTGGAAGCTCACCCTTGTCATCATCTCCATAAGCCCCCTGCTAGGCATCTCAGGTGCTGTCATTACCAAGTGATGACCTCATTCACGTCGAGGGAGCAGACAGCATATGCGAAAGCTGGAGCTGTAGCTGAAGAGGTGCTGTCTGCCATCAGAACTGTCTTTGCCTTTGGAGGACAGAAGAAGGAACTAaagagGTATCAGAAAAACCTGGAAGAAGCCAAGAACGTTGGTATAAAGAAAGCCATTACAGTAAACATTGCTGTGGGTTTCACATACTTCATGATCTACATCTCCTACGCTCTGTCCTTCTGGTATGGCAGCACGCTGATTTTCGCTGGAGAGTATGACATCGGAACACTCCTGACAGTTTTTTTCGCTGTTGTGATTGGAGCATTCGGCCTTGGCCAGACCTCTCCTAACATTCAAGCGTTTTCTAGCGCACGAGGGGCTGCTCACAAGGTTTTTAACATCATCGATCATAAATCCAGCATCAACAGTTTCTCAGATGAAGGCCACAAACCCGACATGGTCAAAGGAAATATTGAGTTCAAAGACGTTCACTTTAGCTACCCTTCGCGGCAGGATGTGAAAGTCCTAAATGGCGTGAATCTTAAGATCAGCAGTGGACAGACTATTGCTCTTGTAGGGAGCAGCGGTTGTGGTAAAAGTACAACAGTCCAACTGATTCAGCGCTTCTACGACCCCCAAGAAGGAGCAGTGAGTATAGATGGCCATGACATTCGCACTCTGAACGTGCGTTGTCTGAGGGAGATGATCGGCGTTGTGAGTCAGGAGCCCGTTCTTTTTGCCACCACAATTGCCGAGAACATTCGATATGGCCGTGAGGATGTGACGCAGGAGGAGATAGAGCAGGCCACGCGTGAAGCCAATGCTTATGATTTCATCATGAAACTTCCTGATAAATTTGAGACTCTGGTGGGAGACAGAGGCACACAGATGAGTGGAGGACAGAAACAGCGAATTGCCATCGCCCGAGCTCTTGTGCGCAATCCCAAGATCCTCCTGTTGGATGAGGCAACATCAGCTTTGGACACAGAAAGTGAGGCGATTGTACAAGCAGCCCTGGATAAGGTGAGACTTGGCAGGACGACCATCATAGTGGCCCACCGTTTGTCCACTATCCGCAATGCTGACGTCATCGCTGGATTCCAGAACGGGAACATTGTAGAGCTCGGCACACACGATGAACtgatggagagaaagggagtCTACCACTCACTGGTCACTATGCAGACGTTTAAGAGCACAGAAGCCACAGAATTAAAAGCAGAGGAGGCAGGGCTGGATGAGAAGAGCCCCTCTACCACGTCtgtgacagaacacacactctacagaCAGAAATCCAAGAGTTTCATTGGCTCAGAGAAAGGCCAGGAGGATGAACTCAAAGATTCAGCACAGGAGGAAAAGGTCCCAGAAGTGTCATTCTTCAGAGTACTGAGTCTGAATAAGGCAGAATGGCCCTACATGGTGGTGGGCATCTTCTGTGCGATCATCAATGGGGGCCTGCAGCCTGCTTTTGCTGTTATCTTCTCCAAAATCACTGCTgtGTTTGCTGAGGTAAACGAGGACATTAAAAGGGAAAAGGCGAATCTCTTCTCACTGCTGTTTGCTATCATTGGGGTGGTTTCCTTCATCGCTCTTTTCTTACAGGGTTTCTGTTTTGGGAAAGCTGGTGAGATTCTGACCATGAGACTGAGGTACAGAGCCTTTAAATCCATGATGAGACAGgacCTAGGTTGGTATGATGACCCTAAGAATAGTGTGGGAGCACTGACGACCAGACTGGCCACAGACACTGCTCAAGTGCAGGGTGCAACGGGGTTGAGACTGGCCACATTGGCTCAGAATGTGGCCAACCTTGGCACTGCAATCATCATCTCGTTTGTGTACGGCTGGCAGCTCaccctcctcatcctctccaTTGTGCCAGTTATGGCTGTAGCAGGAGCTATTCAAATGAAGTTGTTAGGAGGCCATGCTGCAAAGGACAAGAAGGAGTTAGAGCAAGCTGGAAAGatTGCTACTGAAGCCATAGAAAATATCCGCACAGTCGTATCATTGACCAGAGAGAGGAAGTTTGAGAGTCTTTACCAGCAGAACCTAATTGTTCCATACAAgaatgCTCAGAAGAAGGCACATATCTTTGgctttactttctctttttcccaAGCCATGATCTACTTTGCCTATGCAGGCTGCTTCAAGTTTGGTGCATGGCTCATTGAGCAGAAAATGATGACGTTTGAGGGTGTTTTTCTtgtaatcTCAGCTGTAATATATGGAGCCATGGCAATGGGAGAAGCCAACTCCTTTACTCCAAACTACGCCAAGGCTAAGATGTCGGCCTCCCATATCCTAATGCTCATCAATCGAGTGCCAGATATCGACAATGACTCAGAGAAGGGAGAAAAGCCGGATCACTTCGAAGGGAATGTGCGCTTTCAGGATGTGAAATTTAGATATCCGTCACGGCCAGACGTGCCTGTACTGCAGGGCCTGCGGCTCAGAGTGAAGAAGGGTCAGACCCTTGCTCTGGTGGGCAGCAGCGGCTGTGGCAAGAGTACCACCATACAGCTGCTGGAGAGATTTTACGATCCCCTAGAAGGCACagtgATGCTAGATGATAACAACGTCAAACAGCTAAACATCCACTGGCTGCGCTCTCAGATTGGTATTGTATCCCAAGAGCCTGTGCTATTTGACTGCAGCCTGGCCGAGAACATCGCATACGGAGATAATAGCAGGCAGGTCGCTCAGGAGGAGATCGAACAAGCTGCCAAGGCTGCCAATATACACTCTTTCGTAGAGGGGCTTCCACAGCAATATCAGACTCAGGCAGGTGATAAAGGCACTCAGCTGTCAGGCGGACAGAAGCAGCGCATCGCTATTGCTAGAGCCATCCTGCGCAACCCCAAACTGCTGCTACTGGACGAGGCCACATCGGCTCTTGACACAGAAAGTGAAAAGATCGTGCAAGAAGCCTTGGATAAGGCTCGTGAGGGTCGTACCTGCATCATAGTGGCTCACCGGCTGTCCACCATCAAGAATGCTGATGTTATTGCTGTGTTTCAGAATGGTGTGGTGGTGGAGCAgggcacacacaaacagctccTCAGCCAGCAGGGGGTTTACTACACCCTCGTCAATTCCCAAATGGGTTACAGCAAATAGGCAACTACTTGAGAAGAATGACAGGGAATCAGGATGTTTTATGCAGTATGGAAATTTAACTTTACTGCAAAGAGGAATGGGGTTGATCATAACATTTGAGATGATCTGTTATGTAAGACAGGATTTAGATGAGGTCGtaagatttaatatttaaaagctgTAATAGATGTGGTAGAGGAAAAACCATGGTCACAGTAAGAAAAGTGACATGGACAGAAGACTACTGAAGATGTTAGTACTTTTAAAATAACCTCTGTCTGCTGGACATGTACTCACTTCTAATCTGTAAGTTTATTTAACTATTTCACTCACTCAGTTCAGCTTCATAATCAGTTACAATCCATAATACAACTAAAcgcatttattaaaataacaatttagcCACACACTTCCAATCATAATGACAGGGAGAGATATGGAGTCTGATTTACAGCGAGCCAAAATGTGCCACAGAAGTAATAAGAATCATTGGCTACTTTGTGTTTGGCAAGTTTGAATGTATGTAATTATGactaatacatatttatttaaattaaggaaggtttataaagaaaacaggttttcaaaaataaaaattggttctgaattattattaattcttataattattattaaagttctGTGATGGCACTGTATTGTGTTCTAATAGGGcacaaatgtttttatactggctagctacttttttttggaataaaGTTTCACTTATTTACATTT

Function

symbol description
abcb4 Enables ABC-type protein transporter activity; efflux transmembrane transporter activity; and toxin transmembrane transporter activity. Acts upstream of or within response to toxic substance. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in digestive system and head. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); cholestasis (multiple); human immunodeficiency virus infectious disease (multiple); and leukemia (multiple). Orthologous to several human genes including ABCB4 (ATP binding cassette subfamily B member 4).
abcb1 Enables several functions, including ATP binding activity; ATPase-coupled intramembrane lipid transporter activity; and ubiquitin protein ligase binding activity. Involved in several processes, including lipid translocation; regulation of anion transport; and xenobiotic detoxification by transmembrane export across the plasma membrane. Located in apical plasma membrane; cell surface; and nucleoplasm. Implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); human immunodeficiency virus infectious disease (multiple); inflammatory bowel disease (multiple); and leukemia (multiple). Biomarker of several diseases, including familial temporal lobe epilepsy 3; human immunodeficiency virus infectious disease; kidney cancer (multiple); nasal type extranodal NK/T-cell lymphoma; and ovarian cancer.

NR:

description
multidrug resistance protein 1

GO:

id name namespace
GO:0055085 transmembrane transport biological_process
GO:0016021 integral component of membrane cellular_component
GO:0005524 ATP binding molecular_function
GO:0042626 ATPase-coupled transmembrane transporter activity molecular_function

KEGG:

id description
K05658 ABCB1, CD243; ATP-binding cassette, subfamily B (MDR/TAP), member 1

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026924200.2 True 4703 mRNA 0.46 28 5332129 5349833
XM_026924201.2 False 3975 mRNA 0.46 22 5332129 5345883

Neighbor

gene id symbol gene type direction distance location
rpp38 rpp38 coding downstream 23025 5307441 ~ 5309104 (-)
si:dkey-65b12.6 LOC108256587 coding downstream 115829 5205561 ~ 5216300 (-)
LOC117595762 NA coding downstream 153111 5178282 ~ 5179018 (-)
LOC117595761 NA coding downstream 163503 5167096 ~ 5168626 (-)
brd9 brd9,LOC107754443,LOC107659091 coding downstream 234943 5085898 ~ 5097186 (-)
slc25a40 slc25a40,LOC107666862,LOC107592430 coding upstream 41584 5391417 ~ 5400856 (-)
cldn12 cldn12 coding upstream 108400 5458233 ~ 5463036 (-)
washc5 kiaa0196,strumpellin coding upstream 143396 5493229 ~ 5512596 (-)
LOC113532914 LOC108256385,LOC108440755,LOC103044808 coding upstream 165009 5514842 ~ 5522545 (-)
LOC113532747 atad2 coding upstream 172960 5522793 ~ 5540977 (-)
G326995 NA non-coding downstream 17474 5314207 ~ 5314655 (-)
G326989 NA non-coding downstream 21864 5310049 ~ 5310265 (-)
G326981 NA non-coding downstream 36897 5294732 ~ 5295232 (-)
G326960 NA non-coding downstream 74853 5257051 ~ 5257276 (-)
G326958 NA non-coding downstream 76118 5255795 ~ 5256011 (-)
G327100 NA non-coding upstream 42389 5392222 ~ 5393582 (-)
G327362 NA non-coding upstream 388704 5738537 ~ 5739588 (-)
G327505 NA non-coding upstream 486237 5836070 ~ 5836306 (-)
G327507 NA non-coding upstream 487656 5837489 ~ 5837782 (-)
G327508 NA non-coding upstream 488050 5837883 ~ 5838277 (-)
ubr5 ubr5 other downstream 354602 4932155 ~ 4977527 (-)
LOC113532858 LOC103367052,LOC107379323,LOC101466533,LOC100706402,LOC103139281,LOC108413244,LOC102311978,LOC103477771,LOC567622 other downstream 984876 4308606 ~ 4347253 (-)
vsig10l vsig10l other downstream 1366014 3957497 ~ 3966115 (-)
znf385d znf385d other downstream 1535761 3720689 ~ 3796368 (-)
LOC113532799 rftn1 other downstream 1927711 3319544 ~ 3404418 (-)
zfpm2a zfpm2,zfpm2a,LOC107714317,LOC107592441 other upstream 479641 5829474 ~ 5978379 (-)
arhgap33 LOC108256528,LOC108438098,LOC106605587 other upstream 906570 6256403 ~ 6383588 (-)
G328342 LOC108256401 other upstream 1706961 7056794 ~ 7062428 (-)
sec61b sec61b,LOC102796100 other upstream 2028898 7378731 ~ 7386347 (-)
LOC113541109 NA other upstream 4801664 10151497 ~ 10156800 (-)

Expression


Co-expression Network