drd3 (drd3)



Basic Information


Item Value
gene id drd3
gene name drd3
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information


Item Value
chromosome id NC_047616.1
NCBI id CM018562.1
chromosome length 21037487
location 17336192 ~ 17353309 (+)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence


>XM_026938106.2
tggAGAGCGAGGACCATCACTCACTTCTCATGTCCAATGCTGCTTTAAGGACTTCTGCGCTGATGGACAAATCTCAGATCCATCTTTTGCACTTTGTTGAAAGAAGATCTGGTGCAGGATGTTCTCCAGCGTGAAAAGCGCTCGGCTCGTGCACACGGGAACAGCTGGAAAAGGCGCGCGCTCTCAGGAGCCGCACGGAGATGCGTCCGCACGGCACGTGCTCGCAAACAACTCCTGGATTTTAGTGAAATAAATGGATGACAGAAAGCGCAGTGGGGGTCTTTCAAATCCTCTGTGCAGCACTGTGCATTGATGCCAAGCTCTATAtgctctctgtcctgaagaagacAGGGGGGGAATGGAGAAGAGGACAGGCGAAGTGTCGGGAGAAGTTTGAGCGCACAGGAGCAGGTGCTTTCCCGAGCTGAACGAGCAGCACAGGTTTTACTATCCATGGCAATGTTACACAGCAGTGAATGGTGGTGGAATGACTCTGAGCGATCTGCAAATGCGATGCCGAACTCCAGCCTGGGTCCAGCTGTGGAGGATGTGGTGCGCAACTACTACGCCATGCTCTATTCGCTACTTATCCTGGCGATTGTATTCGGGAATGTGCTAGTTTGTTTGGCAGTGGTCAGAGAGAAGTCGCTTCAAACCACGACCAATTATCTTGTGGTTAGTCTGGCTGTGGCTGATCTGCTGGTGGCTTCGCTGGTCATGCCTTGGGCTGTCTATTTAGAGGTGGTTGGTGGCTCTTGGCTCTTTAGCCGTTTGtactgcaatatttttgtgACGTTGGACGTGATGATGTGTACAGCCAGCATCCTCAACCTGTGCGCCATCAGCATCGACAGGTACACAGCCGTGGTGATGCCTGTACTGTACAACACAACTGACAGTTCACGTAAAAGAGTGTCAGTCATGATAGCCACAGTGTGGATCCTGGCCTTCGCTGTCTCCTGCCCTTTACTGTTTGGCTTCAACACCACAGaCGATCCACTGGTGTGCTCCATATCGAACCCTGATTTTGTCATCTACTCATCTGTAGTATCGTTCTACCTTCCCTTCGTGGTGACGTTGCTGGTTTACGTGCGCATCTACATCTTcctcaggaggaggaggaagaggataaCGTTCCGGCAAGCCAGCAGTGAAGCTCCACCAGGATCTACACTGCCAACTGCAGAGACCTGTTTGCAAGAGGACACTCGAAAAGATAGACGTGACCTGTCTCCCATCAGGATCAATGtgGAGAGCACAGAGAAGGTGGTTCGTCCCCGGCTGCTCCCAGGCTGCCTACGGCGTAAACGACCCAAGACCGTCCCCGTTGATAACTCTCTCCTTCCCCCGGCGGACACGCCGAACTACTGCAGCATTAGCCAGGCCTCCTTCGCACGTACAGAACCCGAGCCCAACCGCGAGGAAGAGGCAgggcaagaagaagaagagcaggCGACTGTGAGGAGTAGTGAGGTGAAGGAGATGTCTAATGGACGTGCTCTCACCACAGTTCGGCCTGCTCGAGTCTCACGATGCAACAACCAGAGCCGCTACAGGAACCGACAGTCCAGAGAGAAGAAAGCCACACAGATGCTGGCTATTGTACTGGGGGTCTTTCTCATCTGCTGGTTGCCCTTCTTTGTGACTCACATCTTGAACACTCACTGCAGGAAGTGTCATGTGCCACCCGAGCTGTACAGCGCCTTTACCTGGCTCGGCTACGTCAACAGCGCCCTCAATCCGGTCATTTACACCACCTTCAACATCGAGTTTCGAAGAGCCTTCATCAAAATCCTGACCTGCTGATCTTGACTTTGCAATTCTTCAAACTTTTCTGCTCTAGGATTGAGTGCCAAAATGTCAAAGAACTTTGAAAGCTGGTCGTAGACTGGCCATGTTCGAAATCACTTCATGCTTCCAACAAAGAGCCCCAGTGAACTGGACATTTAAGAGGCCACAGGATTCAGTAATGAAACGAGGGAATAGAGTGCTAGGCTTCTTGATTCTAGGATGATTGAACTGAAGACTATCAAGGGAAAAGTGATTTGGATCATGTAAACAACACTCAAGAATGCAATTGGCATCCGTTGGACTAAAAGCGTGTGGATTACATATCACTTGAGGACCTGATCTGCGTAATATGACCTAAAAGTGGTTTGGGTTGCATATCAGGAGATCTCAAGGGCTCAATCAGCATCCGAGCCTGTACAAATCATGGACGTAACCAGACTTTGTTCTGTTCCTTACACACTTAAAGAAGCTGTTTTTCCAGTTTCTGGTCTGGTGCTTcatctgtatttgcatgtgtctCTAAGAGTCTGTCTCTGCCCTTTTGGGTGGAAATGTTCAGAAAGCATCCATCCAGTGTTTGAGGAAGTGAAGTATTATTAAGTCTAGTACACGTCTGGGACTAGCTTCTTTAAATGGGATGCTTTGAGGTCTGAGTGGCACCTAAGACTTATGAAAACCAT
>XM_034298150.1
tggAGAGCGAGGACCATCACTCACTTCTCATGTCCAATGCTGCTTTAAGGACTTCTGCGCTGATGGACAAATCTCAGATCCATCTTTTGCACTTTGTTGAAAGAAGATCTGGTGCAGGATGTTCTCCAGCGTGAAAAGCGCTCGGCTCGTGCACACGGGAACAGCTGGAAAAGGCGCGCGCTCTCAGGAGCCGCACGGAGATGCGTCCGCACGGCACGTGCTCGCAAACAACTCCTGGATTTTAGTGAAATAAATGGATGACAGAAAGCGCAGTGGGGGTCTTTCAAATCCTCTGTGCAGCACTGTGCATTGATGCCAAGCTCTATAtgctctctgtcctgaagaagacAGGGGGGGAATGGAGAAGAGGACAGGCGAAGTGTCGGGAGAAGTTTGAGCGCACAGGAGCAGGTGCTTTCCCGAGCTGAACGAGCAGCACAGGTTTTACTATCCATGGCAATGTTACACAGCAGTGAATGGTGGTGGAATGACTCTGAGCGATCTGCAAATGCGATGCCGAACTCCAGCCTGGGTCCAGCTGTGGAGGATGTGGTGCGCAACTACTACGCCATGCTCTATTCGCTACTTATCCTGGCGATTGTATTCGGGAATGTGCTAGTTTGTTTGGCAGTGGTCAGAGAGAAGTCGCTTCAAACCACGACCAATTATCTTGTGGTTAGTCTGGCTGTGGCTGATCTGCTGGTGGCTTCGCTGGTCATGCCTTGGGCTGTCTATTTAGAGGTGGTTGGTGGCTCTTGGCTCTTTAGCCGTTTGtactgcaatatttttgtgACGTTGGACGTGATGATGTGTACAGCCAGCATCCTCAACCTGTGCGCCATCAGCATCGACAGGTACACAGCCGTGGTGATGCCTGTACTGTACAACACAACTGACAGTTCACGTAAAAGAGTGTCAGTCATGATAGCCACAGTGTGGATCCTGGCCTTCGCTGTCTCCTGCCCTTTACTGTTTGGCTTCAACACCACAGaCGATCCACTGGTGTGCTCCATATCGAACCCTGATTTTGTCATCTACTCATCTGTAGTATCGTTCTACCTTCCCTTCGTGGTGACGTTGCTGGTTTACGTGCGCATCTACATCTTcctcaggaggaggaggaagaggataaCGTTCCGGCAAGCCAGCAGTGAAGCTCCACCAGGATCTACACTGCCAACTGCAGAGACCTGTTTGCAAGAGGACACTCGAAAAGATAGACGTGACCTGTCTCCCATCAGGATCAATGtggtaaatGAGAGCACAGAGAAGGTGGTTCGTCCCCGGCTGCTCCCAGGCTGCCTACGGCGTAAACGACCCAAGACCGTCCCCGTTGATAACTCTCTCCTTCCCCCGGCGGACACGCCGAACTACTGCAGCATTAGCCAGGCCTCCTTCGCACGTACAGAACCCGAGCCCAACCGCGAGGAAGAGGCAgggcaagaagaagaagagcaggCGACTGTGAGGAGTAGTGAGGTGAAGGAGATGTCTAATGGACGTGCTCTCACCACAGTTCGGCCTGCTCGAGTCTCACGATGCAACAACCAGAGCCGCTACAGGAACCGACAGTCCAGAGAGAAGAAAGCCACACAGATGCTGGCTATTGTACTGGGGGTCTTTCTCATCTGCTGGTTGCCCTTCTTTGTGACTCACATCTTGAACACTCACTGCAGGAAGTGTCATGTGCCACCCGAGCTGTACAGCGCCTTTACCTGGCTCGGCTACGTCAACAGCGCCCTCAATCCGGTCATTTACACCACCTTCAACATCGAGTTTCGAAGAGCCTTCATCAAAATCCTGACCTGCTGATCTTGACTTTGCAATTCTTCAAACTTTTCTGCTCTAGGATTGAGTGCCAAAATGTCAAAGAACTTTGAAAGCTGGTCGTAGACTGGCCATGTTCGAAATCACTTCATGCTTCCAACAAAGAGCCCCAGTGAACTGGACATTTAAGAGGCCACAGGATTCAGTAATGAAACGAGGGAATAGAGTGCTAGGCTTCTTGATTCTAGGATGATTGAACTGAAGACTATCAAGGGAAAAGTGATTTGGATCATGTAAACAACACTCAAGAATGCAATTGGCATCCGTTGGACTAAAAGCGTGTGGATTACATATCACTTGAGGACCTGATCTGCGTAATATGACCTAAAAGTGGTTTGGGTTGCATATCAGGAGATCTCAAGGGCTCAATCAGCATCCGAGCCTGTACAAATCATGGACGTAACCAGACTTTGTTCTGTTCCTTACACACTTAAAGAAGCTGTTTTTCCAGTTTCTGGTCTGGTGCTTcatctgtatttgcatgtgtctCTAAGAGTCTGTCTCTGCCCTTTTGGGTGGAAATGTTCAGAAAGCATCCATCCAGTGTTTGAGGAAGTGAAGTATTATTAAGTCTAGTACACGTCTGGGACTAGCTTCTTTAAATGGGATGCTTTGAGGTCTGAGTGGCACCTAAGACTTATGAAAACCAT

Function


symbol description
drd3 Predicted to enable G protein-coupled receptor activity and dopamine neurotransmitter receptor activity, coupled via Gi/Go. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; negative regulation of cytosolic calcium ion concentration; and regulation of ion transport. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in myotome; nervous system; and somite. Human ortholog(s) of this gene implicated in Parkinson's disease; essential tremor; essential tremor 1; and schizophrenia. Orthologous to human DRD3 (dopamine receptor D3).

NR:

description
unnamed protein product

GO:

id name namespace
GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway biological_process
GO:0005887 integral component of plasma membrane cellular_component
GO:0004952 dopamine neurotransmitter receptor activity molecular_function

KEGG:

id description
K04146 DRD3; dopamine receptor D3

RNA


RNA id representative length rna type GC content exon number start site end site
XM_026938106.2 False 2471 mRNA 0.50 8 17336192 17353309
XM_034298150.1 True 2477 mRNA 0.50 8 17336192 17353309

Neighbor


gene id symbol gene type direction distance location
si:ch211-161h7.8 LOC108256135 coding upstream 2683 17329834 ~ 17333509 (+)
fam162a NA coding upstream 20492 17310721 ~ 17315700 (+)
LOC113541297 LOC108256406 coding upstream 36802 17296573 ~ 17299390 (+)
LOC117595788 NA coding upstream 45297 17287140 ~ 17290895 (+)
LOC113541296 csta,LOC108256407,LOC107654238,LOC107701640,LOC108256406,LOC108256405,LOC107591268 coding upstream 49456 17285104 ~ 17286736 (+)
ccdc191 ccdc191 coding downstream 24992 17378301 ~ 17390639 (+)
urad urad coding downstream 78737 17432046 ~ 17434825 (+)
lnx2a lnx2,lnx2a,LOC107716412,LOC107584972,LOC107701681,LOC107591221 coding downstream 97414 17450723 ~ 17466452 (+)
usp12a usp12,usp12a,LOC107705210,LOC107584971,LOC107591222,LOC107654221 coding downstream 130384 17483693 ~ 17492318 (+)
gpr12 gpr12,LOC107701646,LOC107716385,LOC107654195,LOC107705188 coding downstream 142768 17496077 ~ 17503703 (+)
G333360 NA non-coding upstream 149517 17186129 ~ 17186675 (+)
G333244 map3k20,LOC108439325,LOC108256334,LOC102795565,LOC101475626 non-coding upstream 438337 16893006 ~ 16897855 (+)
LOC113541357 NA non-coding upstream 446031 16888906 ~ 16890161 (+)
G333232 NA non-coding upstream 506213 16732916 ~ 16829979 (+)
G333148 NA non-coding upstream 702409 16605148 ~ 16633783 (+)
G333548 NA non-coding downstream 9562 17362871 ~ 17363075 (+)
G333582 NA non-coding downstream 92876 17446185 ~ 17447043 (+)
G333787 NA non-coding downstream 314327 17667636 ~ 17667844 (+)
G333791 NA non-coding downstream 317107 17670416 ~ 17670625 (+)
G333779 usf3 non-coding downstream 354413 17707722 ~ 17712380 (+)
G333388 csta,LOC108256407,LOC107654238,LOC107701640,LOC108256406,LOC108256405,LOC107591268 other upstream 34188 17285082 ~ 17302004 (+)
hhatlb hhatl,hhatlb,LOC108256744,LOC107585011,LOC107701661 other upstream 226165 17100164 ~ 17110027 (+)
G332636 NA other upstream 1769529 15566175 ~ 15566663 (+)
stau2 stau2,LOC107691439 other upstream 2021224 15134353 ~ 15314968 (+)
rnf6 rnf6,LOC106590444 other downstream 182635 17535944 ~ 17542387 (+)
pan3 pan3,LOC107705213 other downstream 408222 17761531 ~ 17796521 (+)
G333943 LOC108256468 other downstream 633453 17986762 ~ 17993014 (+)
mtfr1 mtfr1 other downstream 962045 18315354 ~ 18323295 (+)
mcmdc2 mcmdc2 other downstream 1114569 18467878 ~ 18486009 (+)

Expression



Co-expression Network