mcoln1a (mcoln1,mcoln1a,LOC108428233,LOC107561871,LOC107676888,LOC107718592,LOC107603030)


Basic Information

Item Value
gene id mcoln1a
gene name mcoln1,mcoln1a,LOC108428233,LOC107561871,LOC107676888,LOC107718592,LOC107603030
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047620.1
NCBI id CM018566.1
chromosome length 19313417
location 11025293 ~ 11046065 (-)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026932266.2
ACTCAGTTCACAAGGACCATCCGGTTAAAATTTGGTATCTTTAAACGTTTTGACTCTATGGAAGGAAACGAGAAGTTACCAGCAAACAGAAGTCGCCTGAAAAGTGAAAGGAAAGAGAAGTGTGTCGTCACGCGGTGTGGTCACATGACCGCTGTGTGGAAGCGCGAGCGTCCTCTCCGGGTCTCTACAGAGAGCTCTATAACACAGCGCGAGCCGAGCGCGCACACGAAAAACCAACGCAAGCCTTTTATTTTTTGCGGATTAGCACAGGTTtgttttctattattttaatgcatCGTGACCCAGACTCCCTTTTGATGACGGATATTTCTTTCGCGCTGCCAACATGGCCGTGGTTGACCAAAATAACGCCGTTCACGACTCCACCGaAAGGGATCGATTGCTGTCTCCTGTGAACTGCTATGGTTCTCATGACTGCAGCATTGACCATGGCAACTCCAAGTTGTACCCAGCAAAAGGAACCTGGGTTACCATGGACCAGGAAGAGGAAGAGTTGAGGAGGAAGTTGAAATATTTCTTCATGAGCCCATGTGATAAGTACCATGCCAAGGGCAGAAAGCCATTTAAATTGGTCCTGCAGCTCCTAAAGATCATCCTAGTGACAGCACAGCTTGTGCTATTTGGTTTGAGTAACCAGATGGTGGTGAcatttaaagaagaaaacacagcCTCCTTTAAACATCTCTTCCTTAAAGACTACAGCGATGGTGCAGATGACACACTGGCAGTGTACACGCAGAGTGACGTCTATGAACACATCTATTACGCAATAGAACAGTACCTGCACTTGCCGGACACCACTGTGGGGCGCTACGCATACGTGTACGGAGTGGGTGTCAACGGTagtgctctgtctctctgccagCAATATTATAAAAAAGGCCGCATCGACCCAGCAAATGACACCTTCATCATCGACCCACACATTATTACAGATTGTGTAGGAGTCTCACCGCTCGATGTACCTGATGGCTTTTTGAAAAAAGAGTACAAAAATTTCACTCTTAAATTTCACAAGCTCATCAATGTTACAATACAGTTTCAGCTAAAGGCTATAAATCTTCAGACCATCATAAACAACGAGATTCCAGACTGTTACACTTTTATAATCACGATCGTCCTGGACAATAAGGCTCACAGTGGCAAGGTGAAGATTAGTCTGGATAACCAGGTCTCTATCAAGGAGTGCAGAGACCCCAGTGTATCCGGCCATGCGGAGAACTACACCCGGGTGGCCTTTGATGTGGCTGTAGCGATGATTTGTGGCCTCTCTCTGGTGCTCTGTGGGCGCTCCATTCTCAGAGGAATCCTCCTTCAGCATGAGTTTGTACagtactttaaaaataaactgaagcacacagtttGTTGGGGGGACAGGATGGAGTTCATCAATGGCTGGTACATCCTGCTCATCATCAGTGACCTGCTTACCATCGCTGGCTCCTTCATAAAGATTGGCATTGAGTCCAAGAACATCTCGTCCTATGACGTATGTGGGATTTTGTTGGGAACATCAACACTGTTGGTGTGGGTGGGGGTGATTCGCTACCTCAGCTTCTTCCAGAAGTACAATATTCTGATCGTGACGTTACGTGCAGCGTTCCCTAACGTGATCCGTTTCTGCTGCTGTGTGGCAGTGATCTATCTGGGATACTGCTTCTGTGGCTGGATTGTTTTAGGGCCATACCACGTCAAGTTCCGCTCTCTGTCCATGGTGTCAGAGTGCCTGTTCTCTCTGATAAATGGAGATGACATGTTTGTCACTTTCAGTGGCATGCAGGAGAGCAGCACACTGGTGTGGGTCTTCAGCCAGGTGTACCTGTACACATTTATCTCTCTGTTCATTTACATGGTGCTCTCACTCTTCATCGCCCTCATCACCGGGGCGTACGAGACCATCAAGCACCAAACTCAGGAGCCCATTCACATCACCGATTTGCATGCGTTCATCGCCGAGTGCAAAGACACACCCAGCTCTGGAAAGTTCCGGGGACTGGAGACGTCACCGTGCTccttcttctgctgctgtgacaGGACCACCACCTATGAAGACGTTCTACTGGTGAACTAGTCATTCAACTACAGCTCTTATGCTCCCTGCTGGTGACAGTATGATGCTGCATCCATTCCACATTTAGAAACAGGATAAGTACAGATACCAAGTGCTGCATCCAATACACATTTACctccacacactcatcacacactgcaggagAGAGGATTTTCCTCCTGGACGTGATGGTGATGTGACTCCTCCTGGATGTGACTCCATATTTTTCAGCTGAGCATGAAAAGAACAGagcaatggggaaaaaaagcaatttcTGTCTGTCACCCGCTTCACAGAGAGCAGCACTACGTTGGTGCAGTGCACAAGCTTTATTTAGGAAAACAGTGTATGTTAGGAGGTCAGTGTTTTATGTGTCGTATTTAACATGATTTTAGTGTGCTGTTAACTTAGCAGGAGCTAATATATTTAGTGCTACTGTTAatgtttttgcattgttttaaaCTTATAAGTCATGGCTAACTTATcattttgaagaagaagaactgcTATTGCACCGTACCTCACTTTCACTACCCCAGACATCTCATCTCAGCACTCATCACTTCCTTAATTTTCCTTTCAAGATACAAGAATAAGCTGCCCTAAGATATAGTGAGCTGTTTTGTAATTTTACGTTCTCCACACATTCCAGCAGCAGTTAGTAAAATATCTGCTCAAACAAATGATTTGGACCACCAACATTCAACCAGTCCAGACAAAGAGGCATCTCTGCCGGCTTAGTCGTGTCTCCTGTCCTTTCAGAAAACTCCCTCTGTTGCACTAGCATTCAGGGATTCTAGCCTAGGCATGTGCTTTGAAGTTAACAATGAAGTGAGGGGCCATGATTGGATTTTGTGCTTCTGTTATCTTCTGCCAAAATTGTGTGTCTTGTGAGTGTCCTAAACTAGTTCATCTTTTGCTGCATTCAAAGAAATGTGTCTAAAATGCTAATACATTTTGCTGATTCAAACTTGAGACAAATGTTAATTGGTTCAGATAAGGTGGGTTTTAATTGGGAACAGCATGTAAAGATTTAGAACATGGTTGAGGGCATTATCACTTTGCAAACTtgggaaataaaagaaattttgATCGGTTCAAACATCTTTGAGAAGCTGAACAGAATGTTCACTGATGCAGTCATTATATCCTGGATAAACTGGAAGGGTTGCATTGACAGTGTATGACCTACATCATGAACAGGAAACACGTATGTTCAGTTCTGGATTTTAGAGATAGCCACTGCAACTATGGGTCGCTGTGGGGACTGATTTAGATTTACTGCCATTAATATTCCTGAAGGTTCATTCAGAAGAGCTAATCGAGTAAGAAATGGAGTGGAGTGTGATTTTGTCGCAATGATGCAGTATGCAAacacttgtttattttcttctctcAGTGACAATGTCTATGTCTGTACagaattttaaattattcatgtatacactcactggtcactttattaggaaaacctgtatacctgctcatttatgcagttatccagtcagccaatcctctggtctctcttatcaa

Function

symbol description
mcoln1a Predicted to enable NAADP-sensitive calcium-release channel activity. Acts upstream of or within several processes, including neuromast hair cell development; regulation of late endosome to lysosome transport; and retina homeostasis. Located in late endosome and lysosome. Is expressed in several structures, including intermediate cell mass of mesoderm; nervous system; pleuroperitoneal region; yolk; and yolk syncytial layer. Used to study mucolipidosis type IV. Human ortholog(s) of this gene implicated in glycoproteinosis and mucolipidosis type IV. Orthologous to human MCOLN1 (mucolipin TRP cation channel 1).
mcoln1 Enables identical protein binding activity and ligand-gated calcium channel activity. Involved in calcium ion transmembrane transport; phagosome maturation; and protein homotetramerization. Located in several cellular components, including Golgi apparatus; late endosome; and lysosome. Is integral component of membrane. Part of receptor complex. Implicated in glycoproteinosis and mucolipidosis type IV.

NR:

description
PREDICTED: mucolipin-1-like isoform X1

GO:

id name namespace
GO:0005764 lysosome cellular_component
GO:0005770 late endosome cellular_component

KEGG:

id description
K04992 MCOLN1, TRPML1; mucolipin 1

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026932266.2 True 3604 mRNA 0.44 15 11025293 11046065

Neighbor

gene id symbol gene type direction distance location
si:ch211-214c7.4 prr36,LOC108258951 coding downstream 5308 11001667 ~ 11019985 (-)
pkn1a LOC108428230,LOC107603033,LOC107712223,LOC107676851,LOC107561874 coding downstream 29528 10949078 ~ 10995765 (-)
map2k7 map2k7,LOC107712243,LOC107692141 coding downstream 78591 10934145 ~ 10946702 (-)
eif5b eif5b,LOC102778822 coding downstream 155197 10850376 ~ 10870096 (-)
arhgef7b arhgef7,arhgef7b,LOC107718510,LOC107567796,LOC107676887 coding downstream 186332 10806435 ~ 10838961 (-)
trappc5 trappc5,LOC107712234,LOC107692146,LOC107676838 coding upstream 694 11046759 ~ 11052112 (-)
si:ch211-243a20.3 NA coding upstream 201744 11247809 ~ 11258475 (-)
emp1 emp1,LOC108258510,LOC107718756,LOC107692152,LOC107603024,LOC107676894 coding upstream 229197 11275262 ~ 11280128 (-)
LOC113537574 LOC108258505,LOC108439141,LOC107376145,LOC106957017,LOC103468358,LOC106517844,LOC102204789,LOC106930820,LOC102799753,LOC101476653,LOC102083067 coding upstream 256718 11302783 ~ 11308486 (-)
si:ch211-239f4.1 evi5l,LOC108258486,LOC108428244,LOC107676895,LOC107718810,LOC107692153 coding upstream 266700 11312765 ~ 11352381 (-)
G374039 NA non-coding downstream 91886 10929739 ~ 10933407 (-)
G374040 NA non-coding downstream 95739 10928467 ~ 10929554 (-)
LOC117596123 NA non-coding downstream 228096 10676632 ~ 10797197 (-)
G373762 NA non-coding downstream 460369 10495636 ~ 10564924 (-)
LOC113537663 NA non-coding downstream 732715 10290637 ~ 10292578 (-)
G374091 sept3 non-coding upstream 21666 11067731 ~ 11067952 (-)
G374093 atf7ip non-coding upstream 38577 11084642 ~ 11120831 (-)
G374105 NA non-coding upstream 93118 11139183 ~ 11139811 (-)
G374111 NA non-coding upstream 101389 11147454 ~ 11147673 (-)
G374196 LOC108258482,LOC107676879,LOC107551907,LOC107603025,LOC107692185 non-coding upstream 190997 11237062 ~ 11237431 (-)
lipt1 lipt1 other downstream 152737 10871224 ~ 10872556 (-)
cab39l cab39l,LOC107676861,LOC107718429 other downstream 589926 10422152 ~ 10435367 (-)
LOC117596103 LOC102201964,LOC102304430 other downstream 1106514 9878843 ~ 9918779 (-)
tsga10 LOC108258346 other downstream 2414452 8591407 ~ 8610841 (-)
LOC113537606 nhlh2,LOC108258389,LOC103035065,LOC108434665,LOC107739819,LOC105019883 other downstream 2592855 8429562 ~ 8432438 (-)
mzt1 mzt1,si:dkey-15d12.2,LOC107556706 other upstream 1032826 12078891 ~ 12084049 (-)
LOC113537246 NA other upstream 1578986 12625051 ~ 12630403 (-)
gyg2 gyg2 other upstream 2261648 13307713 ~ 13320530 (-)
G375428 NA other upstream 2393154 13439219 ~ 13439535 (-)
klf5a LOC108259069 other upstream 2926271 13972336 ~ 13980251 (-)

Expression


Co-expression Network